grimage2timp1 / README.md
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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

grimage2timp1

TIMP-1 inhibits metalloproteinases and has proliferative/anti-apoptotic roles; DNAm TIMP-1 is a GrimAge component.

Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.

Predicts TIMP-1
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type elastic net regression
Year 2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["grimage2timp1"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Lu, A. T., et al. “DNA methylation GrimAge version 2.” Aging 14(23): 9484–9549 (2022).

https://doi.org/10.18632/aging.204434