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library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

hannum

Whole-blood elastic-net predictor of chronological age from 71 CpG methylation fractions, derived in a 482-person primary cohort and validated in 174 independent participants.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts chronological age
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type elastic net regression
Year 2013

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["hannum"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Hannum, G., et al. “Genome-wide methylation profiles reveal quantitative views of human aging rates.” Molecular Cell 49(2), 359–367 (2013).

https://doi.org/10.1016/j.molcel.2012.10.016