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library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---
# hep
HepClock is a hepatocyte-specific chronological-age clock trained by lasso on hepatocyte age-DMCTs identified with CellDMC after estimating five liver cell fractions.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| | |
|---|---|
| **Predicts** | chronological age |
| **Species** | Homo sapiens |
| **Tissue** | liver |
| **Data type** | DNA methylation |
| **Model type** | LASSO regression |
| **Year** | 2024 |
## Use with pyaging
```python
import pyaging as pya
pya.pred.predict_age(adata, ["hep"])
```
Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
## Citation
Tong, Huige, et al. "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution." Aging 16 (2024): 14204–14237.
https://doi.org/10.18632/aging.206184
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