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library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

knight

Elastic-net DNA-methylation estimator of gestational age at birth trained across six cord-blood and neonatal blood-spot cohorts, using 148 CpGs shared across the 27K and 450K arrays.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts gestational age
Species Homo sapiens
Tissue cord blood, neonatal blood spots
Data type DNA methylation
Model type elastic net regression
Year 2016

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["knight"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Knight, A. K., et al. "An epigenetic clock for gestational age at birth based on blood methylation data." Genome Biology 17 (2016): 206.

https://doi.org/10.1186/s13059-016-1068-z