pastamouse / README.md
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Correct publication references, input guidance and output units
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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - transcriptomics

pastamouse

Mouse application of the human Pasta model after one-to-one orthologue mapping, rank transformation, and median imputation of missing genes. The output is a human-year-scaled relative age difference, not mouse chronological age.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts transcriptomic age
Species Mus musculus
Tissue multi-tissue
Data type transcriptomics
Model type orthologue-transferred ridge logistic regression
Year 2026

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["pastamouse"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Salignon, J., et al. (2026). Pasta, a versatile transcriptomic clock, maps the chemical and genetic determinants of aging and rejuvenation. Advanced Science, e76740.

https://doi.org/10.1002/advs.76740