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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

pchannum

Principal-component proxy trained to reproduce the original Hannum whole-blood age-clock score.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts chronological age
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type PCA + elastic net regression
Year 2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["pchannum"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Higgins-Chen, Albert T., et al. "A computational solution for bolstering reliability of epigenetic clocks: implications for clinical trials and longitudinal tracking." Nature Aging 2 (2022): 644–661.

https://doi.org/10.1038/s43587-022-00248-2