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| library_name: pyaging | |
| tags: | |
| - pyaging | |
| - aging-clock | |
| - biology | |
| - dna-methylation | |
| # pedbe | |
| Pediatric chronological-age estimator developed specifically for noninvasive buccal epithelial-cell samples. | |
| Model weights retain the original authors' terms; the pyaging software license does not relicense them. | |
| | | | | |
| |---|---| | |
| | **Predicts** | chronological age | | |
| | **Species** | Homo sapiens | | |
| | **Tissue** | buccal epithelium | | |
| | **Data type** | DNA methylation | | |
| | **Model type** | elastic net regression | | |
| | **Year** | 2020 | | |
| ## Use with pyaging | |
| ```python | |
| import pyaging as pya | |
| pya.pred.predict_age(adata, ["pedbe"]) | |
| ``` | |
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). | |
| ## Citation | |
| McEwen, Lisa M., et al. "The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells." Proceedings of the National Academy of Sciences 117 (2020): 23329–23335. | |
| https://doi.org/10.1073/pnas.1820843116 | |