metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
senmortalityage
Senescence-enriched elastic-net Cox predictor of mortality, restricted to direction-concordant senescence/age/mortality CpGs and trained in the Framingham Heart Study.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | mortality risk |
| Species | Homo sapiens |
| Tissue | whole blood |
| Data type | DNA methylation |
| Model type | elastic net Cox regression |
| Year | 2026 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["senmortalityage"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Kasamoto, K., Gibson, J., Moqri, M., Smith, R. & Higgins-Chen, A.T. DNA methylation signatures of cellular senescence are not reversed by senolytic treatment. Aging Cell 25, e70430 (2026).