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metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
systemsageinflammation
Inflammation-system component of Systems Age: a whole-blood DNAm score built from inflammatory biomarkers and mortality training, returned on an age-like scale.
Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.
| Predicts | inflammatory-system biological age |
| Species | Homo sapiens |
| Tissue | whole blood |
| Data type | DNA methylation |
| Model type | PCA + elastic net regression |
| Year | 2025 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["systemsageinflammation"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Sehgal, R., Markov, Y., Qin, C., et al. (2025). Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems. Nature Aging, 5, 1880–1896.