metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
thompson
Full-lifespan multi-tissue mouse DNA-methylation clock fit by elastic net to RRBS CpG methylation across 1,147 samples from ten tissues and multiple strains; the 582-site all-CpG model estimates chronological age and detects intervention- and genotype-associated age acceleration.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | chronological age |
| Species | Mus musculus |
| Tissue | adipose tissue, blood, cerebellum, brain cortex, heart, kidney, liver, lung, skeletal muscle, spleen |
| Data type | DNA methylation |
| Model type | elastic net regression |
| Year | 2018 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["thompson"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Thompson, M. J., Chwiałkowska, K., Rubbi, L. et al. A multi-tissue full lifespan epigenetic clock for mice. Aging (Albany NY) 10, 2832–2854 (2018).