| { |
| "approved_by_author": "\u231b", |
| "citation": "Wang, Y. et al. DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy. BMC Genomics 22, 484 (2021).", |
| "citations": 38, |
| "citations_date": "2026-07-05", |
| "clock_name": "xchrom", |
| "data_type": "DNA methylation", |
| "doi": "https://doi.org/10.1186/s12864-021-07675-2", |
| "journal": "BMC Genomics", |
| "last_author": "Leonard C. Schalkwyk", |
| "model_type": "principal component analysis", |
| "n_features": 4047, |
| "notes": "X-chromosome first-principal-component score used with the Y score to infer X dosage and classify 46,XX, 46,XY, 45,X, and 47,XXY samples.", |
| "platform": [ |
| "Illumina 450K", |
| "Illumina EPIC" |
| ], |
| "population": "adults", |
| "predicts": [ |
| "X-chromosome dosage" |
| ], |
| "preprocess": "sex_estimation_autosomal_zscore", |
| "reference_values": true, |
| "research_only": null, |
| "species": "Homo sapiens", |
| "tissue": [ |
| "whole blood" |
| ], |
| "training_target": [ |
| "X-chromosome dosage" |
| ], |
| "unit": [ |
| "unitless" |
| ], |
| "version": "0.5.0", |
| "year": 2021 |
| } |
