design.md + rules.md compliance: dark theme, teal palette, pulsing dot, Pydantic models, api.ts routing, config fixes, db/max_hits threading, Supabase migration 004

fix: Analyze button on retrieve page + sessionStorage handoff to blast wizard

fix: E-value underflow, AlphaFold step, steps_completed append, UniProt always runs

Deploy prep: Render config + Dockerfile, refactored backend auth flow, dashboard, landing page, error states, guest flow

AlphaFold 3D viewer via 3Dmol.js — pLDDT confidence coloring, style selector, spin toggle

Core pipeline testability: progress callback, rate limiter 429, history table

Initial commit: Bio Nexus pipeline engine — BLAST + UniProt + AlphaFold + AI interpretation (Phase 1)