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def runSearchContinuousSets(self, request): """ Returns a SearchContinuousSetsResponse for the specified SearchContinuousSetsRequest object. """ return self.runSearchRequest( request, protocol.SearchContinuousSetsRequest, protocol.SearchContinuousSetsRespo...
def runSearchContinuous(self, request): """ Returns a SearchContinuousResponse for the specified SearchContinuousRequest object. :param request: JSON string representing searchContinuousRequest :return: JSON string representing searchContinuousResponse """ return...
def runSearchRnaQuantificationSets(self, request): """ Returns a SearchRnaQuantificationSetsResponse for the specified SearchRnaQuantificationSetsRequest object. """ return self.runSearchRequest( request, protocol.SearchRnaQuantificationSetsRequest, protoc...
def runSearchRnaQuantifications(self, request): """ Returns a SearchRnaQuantificationResponse for the specified SearchRnaQuantificationRequest object. """ return self.runSearchRequest( request, protocol.SearchRnaQuantificationsRequest, protocol.SearchRnaQu...
def runSearchExpressionLevels(self, request): """ Returns a SearchExpressionLevelResponse for the specified SearchExpressionLevelRequest object. """ return self.runSearchRequest( request, protocol.SearchExpressionLevelsRequest, protocol.SearchExpressionLev...
def populateFromRow(self, dataset): """ Populates the instance variables of this Dataset from the specified database row. """ self._description = dataset.description self.setAttributesJson(dataset.attributes)
def addVariantSet(self, variantSet): """ Adds the specified variantSet to this dataset. """ id_ = variantSet.getId() self._variantSetIdMap[id_] = variantSet self._variantSetNameMap[variantSet.getLocalId()] = variantSet self._variantSetIds.append(id_)
def addBiosample(self, biosample): """ Adds the specified biosample to this dataset. """ id_ = biosample.getId() self._biosampleIdMap[id_] = biosample self._biosampleIds.append(id_) self._biosampleNameMap[biosample.getName()] = biosample
def addIndividual(self, individual): """ Adds the specified individual to this dataset. """ id_ = individual.getId() self._individualIdMap[id_] = individual self._individualIds.append(id_) self._individualNameMap[individual.getName()] = individual
def addFeatureSet(self, featureSet): """ Adds the specified featureSet to this dataset. """ id_ = featureSet.getId() self._featureSetIdMap[id_] = featureSet self._featureSetIds.append(id_) name = featureSet.getLocalId() self._featureSetNameMap[name] = feat...
def addContinuousSet(self, continuousSet): """ Adds the specified continuousSet to this dataset. """ id_ = continuousSet.getId() self._continuousSetIdMap[id_] = continuousSet self._continuousSetIds.append(id_) name = continuousSet.getLocalId() self._contin...
def addReadGroupSet(self, readGroupSet): """ Adds the specified readGroupSet to this dataset. """ id_ = readGroupSet.getId() self._readGroupSetIdMap[id_] = readGroupSet self._readGroupSetNameMap[readGroupSet.getLocalId()] = readGroupSet self._readGroupSetIds.appen...
def addRnaQuantificationSet(self, rnaQuantSet): """ Adds the specified rnaQuantification set to this dataset. """ id_ = rnaQuantSet.getId() self._rnaQuantificationSetIdMap[id_] = rnaQuantSet self._rnaQuantificationSetIds.append(id_) name = rnaQuantSet.getLocalId()...
def getVariantSet(self, id_): """ Returns the VariantSet with the specified name, or raises a VariantSetNotFoundException otherwise. """ if id_ not in self._variantSetIdMap: raise exceptions.VariantSetNotFoundException(id_) return self._variantSetIdMap[id_]
def getVariantSetByName(self, name): """ Returns a VariantSet with the specified name, or raises a VariantSetNameNotFoundException if it does not exist. """ if name not in self._variantSetNameMap: raise exceptions.VariantSetNameNotFoundException(name) return s...
def addPhenotypeAssociationSet(self, phenotypeAssociationSet): """ Adds the specified g2p association set to this backend. """ id_ = phenotypeAssociationSet.getId() self._phenotypeAssociationSetIdMap[id_] = phenotypeAssociationSet self._phenotypeAssociationSetNameMap[ ...
def getFeatureSet(self, id_): """ Returns the FeatureSet with the specified id, or raises a FeatureSetNotFoundException otherwise. """ if id_ not in self._featureSetIdMap: raise exceptions.FeatureSetNotFoundException(id_) return self._featureSetIdMap[id_]
def getFeatureSetByName(self, name): """ Returns the FeatureSet with the specified name, or raises an exception otherwise. """ if name not in self._featureSetNameMap: raise exceptions.FeatureSetNameNotFoundException(name) return self._featureSetNameMap[name]
def getContinuousSet(self, id_): """ Returns the ContinuousSet with the specified id, or raises a ContinuousSetNotFoundException otherwise. """ if id_ not in self._continuousSetIdMap: raise exceptions.ContinuousSetNotFoundException(id_) return self._continuous...
def getContinuousSetByName(self, name): """ Returns the ContinuousSet with the specified name, or raises an exception otherwise. """ if name not in self._continuousSetNameMap: raise exceptions.ContinuousSetNameNotFoundException(name) return self._continuousSet...
def getBiosampleByName(self, name): """ Returns a Biosample with the specified name, or raises a BiosampleNameNotFoundException if it does not exist. """ if name not in self._biosampleNameMap: raise exceptions.BiosampleNameNotFoundException(name) return self._...
def getBiosample(self, id_): """ Returns the Biosample with the specified id, or raises a BiosampleNotFoundException otherwise. """ if id_ not in self._biosampleIdMap: raise exceptions.BiosampleNotFoundException(id_) return self._biosampleIdMap[id_]
def getIndividualByName(self, name): """ Returns an individual with the specified name, or raises a IndividualNameNotFoundException if it does not exist. """ if name not in self._individualNameMap: raise exceptions.IndividualNameNotFoundException(name) return ...
def getIndividual(self, id_): """ Returns the Individual with the specified id, or raises a IndividualNotFoundException otherwise. """ if id_ not in self._individualIdMap: raise exceptions.IndividualNotFoundException(id_) return self._individualIdMap[id_]
def getReadGroupSetByName(self, name): """ Returns a ReadGroupSet with the specified name, or raises a ReadGroupSetNameNotFoundException if it does not exist. """ if name not in self._readGroupSetNameMap: raise exceptions.ReadGroupSetNameNotFoundException(name) ...
def getReadGroupSet(self, id_): """ Returns the ReadGroupSet with the specified name, or raises a ReadGroupSetNotFoundException otherwise. """ if id_ not in self._readGroupSetIdMap: raise exceptions.ReadGroupNotFoundException(id_) return self._readGroupSetIdMa...
def getRnaQuantificationSetByName(self, name): """ Returns the RnaQuantification set with the specified name, or raises an exception otherwise. """ if name not in self._rnaQuantificationSetNameMap: raise exceptions.RnaQuantificationSetNameNotFoundException(name) ...
def getRnaQuantificationSet(self, id_): """ Returns the RnaQuantification set with the specified name, or raises a RnaQuantificationSetNotFoundException otherwise. """ if id_ not in self._rnaQuantificationSetIdMap: raise exceptions.RnaQuantificationSetNotFoundExceptio...
def parseMalformedBamHeader(headerDict): """ Parses the (probably) intended values out of the specified BAM header dictionary, which is incompletely parsed by pysam. This is caused by some tools incorrectly using spaces instead of tabs as a seperator. """ headerString = " ".join( "{}...
def _getReadAlignments( self, reference, start, end, readGroupSet, readGroup): """ Returns an iterator over the specified reads """ # TODO If reference is None, return against all references, # including unmapped reads. samFile = self.getFileHandle(self._dataU...
def convertReadAlignment(self, read, readGroupSet, readGroupId): """ Convert a pysam ReadAlignment to a GA4GH ReadAlignment """ samFile = self.getFileHandle(self._dataUrl) # TODO fill out remaining fields # TODO refine in tandem with code in converters module ret ...
def addReadGroup(self, readGroup): """ Adds the specified ReadGroup to this ReadGroupSet. """ id_ = readGroup.getId() self._readGroupIdMap[id_] = readGroup self._readGroupIds.append(id_)
def getReadGroup(self, id_): """ Returns the ReadGroup with the specified id if it exists in this ReadGroupSet, or raises a ReadGroupNotFoundException otherwise. """ if id_ not in self._readGroupIdMap: raise exceptions.ReadGroupNotFoundException(id_) return se...
def toProtocolElement(self): """ Returns the GA4GH protocol representation of this ReadGroupSet. """ readGroupSet = protocol.ReadGroupSet() readGroupSet.id = self.getId() readGroupSet.read_groups.extend( [readGroup.toProtocolElement() for readGrou...
def getReadAlignmentId(self, gaAlignment): """ Returns a string ID suitable for use in the specified GA ReadAlignment object in this ReadGroupSet. """ compoundId = datamodel.ReadAlignmentCompoundId( self.getCompoundId(), gaAlignment.fragment_name) return str(c...
def getStats(self): """ Returns the GA4GH protocol representation of this read group set's ReadStats. """ stats = protocol.ReadStats() stats.aligned_read_count = self._numAlignedReads stats.unaligned_read_count = self._numUnalignedReads return stats
def getReadAlignments(self, reference, start=None, end=None): """ Returns an iterator over the specified reads """ return self._getReadAlignments(reference, start, end, self, None)
def populateFromRow(self, readGroupSetRecord): """ Populates the instance variables of this ReadGroupSet from the specified database row. """ self._dataUrl = readGroupSetRecord.dataurl self._indexFile = readGroupSetRecord.indexfile self._programs = [] for ...
def populateFromFile(self, dataUrl, indexFile=None): """ Populates the instance variables of this ReadGroupSet from the specified dataUrl and indexFile. If indexFile is not specified guess usual form. """ self._dataUrl = dataUrl self._indexFile = indexFile ...
def toProtocolElement(self): """ Returns the GA4GH protocol representation of this ReadGroup. """ # TODO this is very incomplete, but we don't have the # implementation to fill out the rest of the fields currently readGroup = protocol.ReadGroup() readGroup.id = se...
def getStats(self): """ Returns the GA4GH protocol representation of this read group's ReadStats. """ stats = protocol.ReadStats() stats.aligned_read_count = self.getNumAlignedReads() stats.unaligned_read_count = self.getNumUnalignedReads() # TODO base_cou...
def getExperiment(self): """ Returns the GA4GH protocol representation of this read group's Experiment. """ experiment = protocol.Experiment() experiment.id = self.getExperimentId() experiment.instrument_model = pb.string(self.getInstrumentModel()) experim...
def populateFromHeader(self, readGroupHeader): """ Populate the instance variables using the specified SAM header. """ self._sampleName = readGroupHeader.get('SM', None) self._description = readGroupHeader.get('DS', None) if 'PI' in readGroupHeader: self._pred...
def populateFromRow(self, readGroupRecord): """ Populate the instance variables using the specified DB row. """ self._sampleName = readGroupRecord.samplename self._biosampleId = readGroupRecord.biosampleid self._description = readGroupRecord.description self._pred...
def getNameFromPath(filePath): """ Returns the filename of the specified path without its extensions. This is usually how we derive the default name for a given object. """ if len(filePath) == 0: raise ValueError("Cannot have empty path for name") fileName = os.path.split(os.path.normpat...
def repoExitError(message): """ Exits the repo manager with error status. """ wrapper = textwrap.TextWrapper( break_on_hyphens=False, break_long_words=False) formatted = wrapper.fill("{}: error: {}".format(sys.argv[0], message)) sys.exit(formatted)
def _updateRepo(self, func, *args, **kwargs): """ Runs the specified function that updates the repo with the specified arguments. This method ensures that all updates are transactional, so that if any part of the update fails no changes are made to the repo. """ #...
def addOntology(self): """ Adds a new Ontology to this repo. """ self._openRepo() name = self._args.name filePath = self._getFilePath(self._args.filePath, self._args.relativePath) if name is None: name = getNameFrom...
def addDataset(self): """ Adds a new dataset into this repo. """ self._openRepo() dataset = datasets.Dataset(self._args.datasetName) dataset.setDescription(self._args.description) dataset.setAttributes(json.loads(self._args.attributes)) self._updateRepo(se...
def addReferenceSet(self): """ Adds a new reference set into this repo. """ self._openRepo() name = self._args.name filePath = self._getFilePath(self._args.filePath, self._args.relativePath) if name is None: name = ...
def addReadGroupSet(self): """ Adds a new ReadGroupSet into this repo. """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) dataUrl = self._args.dataFile indexFile = self._args.indexFile parsed = urlparse.urlparse(dataUrl) ...
def addVariantSet(self): """ Adds a new VariantSet into this repo. """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) dataUrls = self._args.dataFiles name = self._args.name if len(dataUrls) == 1: if self._args.na...
def addPhenotypeAssociationSet(self): """ Adds a new phenotype association set to this repo. """ self._openRepo() name = self._args.name if name is None: name = getNameFromPath(self._args.dirPath) dataset = self._repo.getDatasetByName(self._args.datase...
def removePhenotypeAssociationSet(self): """ Removes a phenotype association set from the repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) phenotypeAssociationSet = dataset.getPhenotypeAssociationSetByName( self._args.nam...
def removeReferenceSet(self): """ Removes a referenceSet from the repo. """ self._openRepo() referenceSet = self._repo.getReferenceSetByName( self._args.referenceSetName) def func(): self._updateRepo(self._repo.removeReferenceSet, referenceSet) ...
def removeReadGroupSet(self): """ Removes a readGroupSet from the repo. """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) readGroupSet = dataset.getReadGroupSetByName( self._args.readGroupSetName) def func(): ...
def removeVariantSet(self): """ Removes a variantSet from the repo. """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) variantSet = dataset.getVariantSetByName(self._args.variantSetName) def func(): self._updateRepo(sel...
def removeDataset(self): """ Removes a dataset from the repo. """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) def func(): self._updateRepo(self._repo.removeDataset, dataset) self._confirmDelete("Dataset", dataset.get...
def addFeatureSet(self): """ Adds a new feature set into this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) filePath = self._getFilePath(self._args.filePath, self._args.relativePath) na...
def removeFeatureSet(self): """ Removes a feature set from this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) featureSet = dataset.getFeatureSetByName(self._args.featureSetName) def func(): self._updateRepo(se...
def addContinuousSet(self): """ Adds a new continuous set into this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) filePath = self._getFilePath(self._args.filePath, self._args.relativePath) ...
def removeContinuousSet(self): """ Removes a continuous set from this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) continuousSet = dataset.getContinuousSetByName( self._args.continuousSetName) ...
def addBiosample(self): """ Adds a new biosample into this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) biosample = bio_metadata.Biosample( dataset, self._args.biosampleName) biosample.populateFromJson(self._a...
def removeBiosample(self): """ Removes a biosample from this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) biosample = dataset.getBiosampleByName(self._args.biosampleName) def func(): self._updateRepo(self._re...
def addIndividual(self): """ Adds a new individual into this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) individual = bio_metadata.Individual( dataset, self._args.individualName) individual.populateFromJson(s...
def removeIndividual(self): """ Removes an individual from this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) individual = dataset.getIndividualByName(self._args.individualName) def func(): self._updateRepo(se...
def addPeer(self): """ Adds a new peer into this repo """ self._openRepo() try: peer = peers.Peer( self._args.url, json.loads(self._args.attributes)) except exceptions.BadUrlException: raise exceptions.RepoManagerException("The URL ...
def removePeer(self): """ Removes a peer by URL from this repo """ self._openRepo() def func(): self._updateRepo(self._repo.removePeer, self._args.url) self._confirmDelete("Peer", self._args.url, func)
def removeOntology(self): """ Removes an ontology from the repo. """ self._openRepo() ontology = self._repo.getOntologyByName(self._args.ontologyName) def func(): self._updateRepo(self._repo.removeOntology, ontology) self._confirmDelete("Ontology", on...
def addRnaQuantification(self): """ Adds an rnaQuantification into this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) biosampleId = "" if self._args.biosampleName: biosample = dataset.getBiosampleByName(self._a...
def initRnaQuantificationSet(self): """ Initialize an empty RNA quantification set """ store = rnaseq2ga.RnaSqliteStore(self._args.filePath) store.createTables()
def addRnaQuantificationSet(self): """ Adds an rnaQuantificationSet into this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) if self._args.name is None: name = getNameFromPath(self._args.filePath) else: ...
def removeRnaQuantificationSet(self): """ Removes an rnaQuantificationSet from this repo """ self._openRepo() dataset = self._repo.getDatasetByName(self._args.datasetName) rnaQuantSet = dataset.getRnaQuantificationSetByName( self._args.rnaQuantificationSetName...
def rnaseq2ga(quantificationFilename, sqlFilename, localName, rnaType, dataset=None, featureType="gene", description="", programs="", featureSetNames="", readGroupSetNames="", biosampleId=""): """ Reads RNA Quantification data in one of several formats and stores the da...
def addRNAQuantification(self, datafields): """ Adds an RNAQuantification to the db. Datafields is a tuple in the order: id, feature_set_ids, description, name, read_group_ids, programs, biosample_id """ self._rnaValueList.append(datafields) if len(self._...
def addExpression(self, datafields): """ Adds an Expression to the db. Datafields is a tuple in the order: id, rna_quantification_id, name, expression, is_normalized, raw_read_count, score, units, conf_low, conf_hi """ self._expressionValueList.append(datafields) ...
def createIndices(self): """ Index columns that are queried. The expression index can take a long time. """ sql = '''CREATE INDEX name_index ON Expression (name)''' self._cursor.execute(sql) self._dbConn.commit() sql = '''CREATE INDEX ex...
def writeExpression(self, rnaQuantificationId, quantfilename): """ Reads the quantification results file and adds entries to the specified database. """ isNormalized = self._isNormalized units = self._units with open(quantfilename, "r") as quantFile: q...
def _fetchSequence(ac, startIndex=None, endIndex=None): """Fetch sequences from NCBI using the eself interface. An interbase interval may be optionally provided with startIndex and endIndex. NCBI eself will return just the requested subsequence, which might greatly reduce payload sizes (especially with...
def createBamHeader(self, baseHeader): """ Creates a new bam header based on the specified header from the parent BAM file. """ header = dict(baseHeader) newSequences = [] for index, referenceInfo in enumerate(header['SQ']): if index < self.numChromoso...
def createRepo(self): """ Creates the repository for all the data we've just downloaded. """ repo = datarepo.SqlDataRepository(self.repoPath) repo.open("w") repo.initialise() referenceSet = references.HtslibReferenceSet("GRCh37-subset") referenceSet.popul...
def _configure_backend(app): """A helper function used just to help modularize the code a bit.""" # Allocate the backend # We use URLs to specify the backend. Currently we have file:// URLs (or # URLs with no scheme) for the SqlDataRepository, and special empty:// and # simulated:// URLs for empty o...
def configure(configFile=None, baseConfig="ProductionConfig", port=8000, extraConfig={}): """ TODO Document this critical function! What does it do? What does it assume? """ file_handler = StreamHandler() file_handler.setLevel(logging.WARNING) app.logger.addHandler(file_handler...
def getFlaskResponse(responseString, httpStatus=200): """ Returns a Flask response object for the specified data and HTTP status. """ return flask.Response(responseString, status=httpStatus, mimetype=MIMETYPE)
def handleHttpPost(request, endpoint): """ Handles the specified HTTP POST request, which maps to the specified protocol handler endpoint and protocol request class. """ if request.mimetype and request.mimetype != MIMETYPE: raise exceptions.UnsupportedMediaTypeException() request = reque...
def handleException(exception): """ Handles an exception that occurs somewhere in the process of handling a request. """ serverException = exception if not isinstance(exception, exceptions.BaseServerException): with app.test_request_context(): app.log_exception(exception) ...
def startLogin(): """ If we are not logged in, this generates the redirect URL to the OIDC provider and returns the redirect response :return: A redirect response to the OIDC provider """ flask.session["state"] = oic.oauth2.rndstr(SECRET_KEY_LENGTH) flask.session["nonce"] = oic.oauth2.rndstr...
def checkAuthentication(): """ The request will have a parameter 'key' if it came from the command line client, or have a session key of 'key' if it's the browser. If the token is not found, start the login process. If there is no oidcClient, we are running naked and we don't check. If we're be...
def handleFlaskGetRequest(id_, flaskRequest, endpoint): """ Handles the specified flask request for one of the GET URLs Invokes the specified endpoint to generate a response. """ if flaskRequest.method == "GET": return handleHttpGet(id_, endpoint) else: raise exceptions.MethodNot...
def handleFlaskPostRequest(flaskRequest, endpoint): """ Handles the specified flask request for one of the POST URLS Invokes the specified endpoint to generate a response. """ if flaskRequest.method == "POST": return handleHttpPost(flaskRequest, endpoint) elif flaskRequest.method == "OPT...
def getVariantAnnotationSets(self, datasetId): """ Returns the list of ReferenceSets for this server. """ # TODO this should be displayed per-variant set, not per dataset. variantAnnotationSets = [] dataset = app.backend.getDataRepository().getDataset(datasetId) f...
def auth_decorator(app=None): """ This decorator wraps a view function so that it is protected when Auth0 is enabled. This means that any request will be expected to have a signed token in the authorization header if the `AUTH0_ENABLED` configuration setting is True. The authorization header wi...
def decode_header(auth_header, client_id, client_secret): """ A function that threads the header through decoding and returns a tuple of the token and payload if successful. This does not fully authenticate a request. :param auth_header: :param client_id: :param client_secret: :return: (...
def logout(cache): """ Logs out the current session by removing it from the cache. This is expected to only occur when a session has """ cache.set(flask.session['auth0_key'], None) flask.session.clear() return True
def callback_maker( cache=None, domain='', client_id='', client_secret='', redirect_uri=''): """ This function will generate a view function that can be used to handle the return from Auth0. The "callback" is a redirected session from auth0 that includes the token we can use to authentic...
def render_login( app=None, scopes='', redirect_uri='', domain='', client_id=''): """ This function will generate a view function that can be used to handle the return from Auth0. The "callback" is a redirected session from auth0 that includes the token we can use to authenticate that session. ...
def render_key(app, key=""): """ Renders a view from the app and a key that lets the current session grab its token. :param app: :param key: :return: Rendered view """ return app.jinja_env.from_string(KEY_HTML).render( key=key)
def _decode_header(auth_header, client_id, client_secret): """ Takes the header and tries to return an active token and decoded payload. :param auth_header: :param client_id: :param client_secret: :return: (token, profile) """ try: token = auth_header.split()[1] paylo...
def is_active(cache, token): """ Accepts the cache and ID token and checks to see if the profile is currently logged in. If so, return the token, otherwise throw a NotAuthenticatedException. :param cache: :param token: :return: """ profile = cache.get(token) if not profile: ...
def addReference(self, reference): """ Adds the specified reference to this ReferenceSet. """ id_ = reference.getId() self._referenceIdMap[id_] = reference self._referenceNameMap[reference.getLocalId()] = reference self._referenceIds.append(id_)