LiteFold/InterPro · Datasets at Hugging Face

IPR002557

2,557

Chitin binding domain

Chitin-bd_dom

Domain

40,619

false

This entry represents a chitin binding domain [ ]. It is found in the Peritrophin-A chitin binding proteins, particularly the peritrophic matrix proteins of insects and animal chitinases [ , , ] and related proteins. Copies of the domain are also found in some baculoviruses. It is an extracellular domain characterised ...

[ "GO:0008061", "GO:0005576" ]

[ "chitin binding", "extracellular region" ]

[ "molecular_function", "cellular_component" ]

2

[ "PFAM", "PROFILE", "SMART" ]

[ "PF01607", "PS50940", "SM00494" ]

[ "CBM_14", "CHIT_BIND_II", "ChtBD2" ]

[ 37351, 38914, 34070 ]

3

[ "PROSITEDOC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "PDOC50940", "R-CEL-189085", "R-CEL-6798695", "R-DME-6798695", "R-HSA-189085", "R-HSA-6798695", "R-MMU-189085", "R-MMU-6798695", "R-RNO-189085" ]

[ "PROSITEDOC:PDOC50940", "REACTOME:R-CEL-189085", "REACTOME:R-CEL-6798695", "REACTOME:R-DME-6798695", "REACTOME:R-HSA-189085", "REACTOME:R-HSA-6798695", "REACTOME:R-MMU-189085", "REACTOME:R-MMU-6798695", "REACTOME:R-RNO-189085" ]

9

[ "1dqc", "1waw", "1wb0", "2mfk", "3w4r", "4z4a", "4zce", "5hbf", "5wus", "5wvf", "5wvg", "5wvh", "5zjl", "6bn0", "6g9c", "6g9e", "6so0", "7bwe", "7bwo", "8in3", "8in4", "8in6" ]

22

[ "PUB00003019", "PUB00007195", "PUB00007196", "PUB00018405", "PUB00018406" ]

[ "9651363", "8621536", "9256413", "14563358", "10770921" ]

[ "A type I peritrophic matrix protein from the malaria vector Anopheles gambiae binds to chitin. Cloning, expression, and characterization.", "Characterization of a major peritrophic membrane protein, peritrophin-44, from the larvae of Lucilia cuprina. cDNA and deduced amino acid sequences.", "Antibody-mediated ...

[ 1998, 1996, 1997, 2003, 2000 ]

5

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "freshwater metagenome" ]

[ 246, 39883, 486, 4 ]

4

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 14, 14, 234, 8, 4, 8 ]

6

true

Domain

Chitin binding domain

Chitin-bd_dom

9

IPR002558

2,558

I/LWEQ domain

ILWEQ_dom

Domain

11,174

false

The I/LWEQ domain is a ~250-residue actin-binding module that is found in the C termini of functionally diverse proteins from yeast to mammals. The I/LWEQ domain contains four conserved blocks and has been named after the conserved initial residues of blocks 1-4. The I/LWEQ domain is generally found near the C terminus...

[ "GO:0003779" ]

[ "actin binding" ]

[ "molecular_function" ]

1

[ "PFAM", "PROFILE", "SMART" ]

[ "PF01608", "PS50945", "SM00307" ]

[ "I_LWEQ", "I_LWEQ", "ILWEQ" ]

[ 10965, 10939, 10869 ]

3

[ "PROSITEDOC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACT...

[ "PDOC50945", "R-CEL-432722", "R-CEL-8856828", "R-DDI-114608", "R-HSA-114608", "R-HSA-354192", "R-HSA-354194", "R-HSA-372708", "R-HSA-381038", "R-HSA-399955", "R-HSA-432722", "R-HSA-445355", "R-HSA-5674135", "R-HSA-6802946", "R-HSA-6802948", "R-HSA-6802952", "R-HSA-6802955", "R-HSA-...

[ "PROSITEDOC:PDOC50945", "REACTOME:R-CEL-432722", "REACTOME:R-CEL-8856828", "REACTOME:R-DDI-114608", "REACTOME:R-HSA-114608", "REACTOME:R-HSA-354192", "REACTOME:R-HSA-354194", "REACTOME:R-HSA-372708", "REACTOME:R-HSA-381038", "REACTOME:R-HSA-399955", "REACTOME:R-HSA-432722", "REACTOME:R-HSA-445...

33

[ "1r0d", "1sj8", "2jsw", "2qdq", "6r9t", "8vdo", "8vdp", "8vdq", "8vdr", "9az6", "9hdd" ]

11

[ "PUB00004911", "PUB00018420", "PUB00033725" ]

[ "9159132", "10581178", "16415883" ]

[ "The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals.", "Functional genomic analysis reveals the utility of the I/LWEQ module as a predictor of protein:actin interaction.", "Structural definition of the F-actin-binding THATCH domain from ...

[ 1997, 1999, 2006 ]

3

[]

0

null

[ "Actinomycetota", "Eukaryota" ]

[ 2, 11172 ]

2

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strai...

[ 6, 25, 8, 13, 26, 1, 30, 1, 1 ]

9

true

Domain

I/LWEQ domain

ILWEQ_dom

1

IPR002562

2,562

3'-5' exonuclease domain

3'-5'_exonuclease_dom

Domain

70,966

false

This entry represents the domain that is responsible for the 3'-5' exonuclease proofreading activity of Escherichia coli DNA polymerase I (polI) and other enzymes which catalyse the hydrolysis of unpaired or mismatched nucleotides. This domain consists of the amino-terminal half of the Klenow fragment in E. coli polI a...

[ "GO:0003676", "GO:0008408", "GO:0006139" ]

[ "nucleic acid binding", "3'-5' exonuclease activity", "nucleobase-containing compound metabolic process" ]

[ "molecular_function", "molecular_function", "biological_process" ]

3

[ "PFAM", "SMART" ]

[ "PF01612", "SM00474" ]

[ "DNA_pol_A_exo1", "35EXOc" ]

[ 63914, 60418 ]

2

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-CEL-6791226", "R-CEL-9930044", "R-DME-6791226", "R-DME-9930044", "R-HSA-174414", "R-HSA-174437", "R-HSA-3108214", "R-HSA-5685938", "R-HSA-5685942", "R-HSA-5693554", "R-HSA-5693568", "R-HSA-5693579", "R-HSA-5693607", "R-HSA-5693616", "R-HSA-6791226", "R-HSA-6804756", "R-HSA-69473",...

[ "REACTOME:R-CEL-6791226", "REACTOME:R-CEL-9930044", "REACTOME:R-DME-6791226", "REACTOME:R-DME-9930044", "REACTOME:R-HSA-174414", "REACTOME:R-HSA-174437", "REACTOME:R-HSA-3108214", "REACTOME:R-HSA-5685938", "REACTOME:R-HSA-5685942", "REACTOME:R-HSA-5693554", "REACTOME:R-HSA-5693568", "REACTOME:...

39

[ "1d8y", "1d9d", "1d9f", "1dpi", "1kfd", "1kfs", "1kln", "1krp", "1ksp", "1l3s", "1l3t", "1l3u", "1l3v", "1l5u", "1lv5", "1njw", "1njx", "1njy", "1njz", "1nk0", "1nk4", "1nk5", "1nk6", "1nk7", "1nk8", "1nk9", "1nkb", "1nkc", "1nke", "1qsl", "1u45", "1u47"...

250

[ "PUB00003905", "PUB00003908", "PUB00004476", "PUB00099670", "PUB00099671" ]

[ "9288107", "9697700", "9224595", "33926956", "15377656" ]

[ "The Werner syndrome protein is a DNA helicase.", "Replication focus-forming activity 1 and the Werner syndrome gene product.", "DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system.", "Noncanonical DNA polymerization by aminoadenine-based siphoviruses.", "The highly p...

[ 1997, 1998, 1997, 2021, 2004 ]

5

[]

[ "IPR037432", "IPR049559", "IPR054690" ]

0

3

0

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 9, 41079, 27314, 1376, 1188 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 87, 7, 10, 10, 2, 12, 18, 3, 60, 13, 1, 1, 117 ]

13

true

Domain

3'-5' exonuclease domain

3'-5'_exonuclease_dom

6

IPR002563

2,563

Flavin reductase like domain

Flavin_Rdtase-like_dom

Domain

67,141

false

This domain can be found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes, and various other oxidoreductase and monooxygenase enzymes [ , , ]. This domain consists of a β-barrel with Greek key topol...

[ "GO:0010181" ]

[ "FMN binding" ]

[ "molecular_function" ]

1

[ "PFAM", "SMART" ]

[ "PF01613", "SM00903" ]

[ "Flavin_Reduct", "Flavin_Reduct" ]

[ 67137, 60120 ]

2

[ "EC" ]

[ "1.5.1" ]

[ "EC:1.5.1" ]

1

[ "1eje", "1i0r", "1i0s", "1rz0", "1rz1", "1usc", "1usf", "1wgb", "1yoa", "2d36", "2d37", "2d38", "2d5m", "2ecr", "2ecu", "2ed4", "2qck", "2r0x", "2r6v", "3bnk", "3bpk", "3cb0", "3e4v", "3fge", "3hmz", "3k86", "3k87", "3k88", "3nfw", "3pft", "3rh7", "3zoc"...

53

[ "PUB00008047", "PUB00016340", "PUB00016341" ]

[ "11017201", "12829278", "15461461" ]

[ "Structural proteomics of an archaeon.", "Microbial ferric iron reductases.", "Aminobacter aminovorans NADH:flavin oxidoreductase His140: a highly conserved residue critical for NADH binding and utilization." ]

[ 2000, 2003, 2004 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Enterobacteria phage VT2-Sa", "Eukaryota", "unclassified sequences" ]

[ 878, 60087, 1, 5395, 780 ]

5

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 1, 2, 2, 1 ]

4

true

Domain

Flavin reductase like domain

Flavin_Rdtase-like_dom

4

IPR002565

2,565

Orbivirus NS3

Orbi_NS3

Family

1,112

false

This is a family of Orbivirus non structural protein of unknown function, but which may play a role in release of the virus from infected cells [ ].

[]

0

[ "PFAM" ]

[ "PF01616" ]

[ "Orbi_NS3" ]

[ 1112 ]

1

[ "GP" ]

[ "GenProp1006" ]

[ "GP:GenProp1006" ]

1

[]

0

[ "PUB00003141" ]

[ "1654377" ]

[ "Localization of the non-structural protein NS3 in bluetongue virus-infected cells." ]

[ 1991 ]

1

[]

0

null

[ "Poseidonibacter ostreae", "Riboviria" ]

[ 1, 1111 ]

2

[]

0

true

Family

Orbivirus NS3

Orbi_NS3

6

IPR002566

2,566

Msp4/OMP-like

Msp4_OMP-like

Domain

6,745

false

This entry includes a number of bacterial surface antigens expressed on the surface of pathogens. The Anaplasma marginale surface proteins are targets of protective immune responses but are antigenically polymorphic [ , ]. They display a β-barrel like fold.

[]

0

[ "PFAM" ]

[ "PF01617" ]

[ "Surface_Ag_2" ]

[ 6745 ]

1

[]

0

[]

0

[ "PUB00001840", "PUB00006309" ]

[ "8294020", "8063397" ]

[ "Derivation of the complete msp4 gene sequence of Anaplasma marginale without cloning.", "The immunoprotective Anaplasma marginale major surface protein 2 is encoded by a polymorphic multigene family." ]

[ 1993, 1994 ]

2

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 6681, 62, 2 ]

3

[]

0

true

Domain

Msp4/OMP-like

Msp4_OMP-like

9

IPR002567

2,567

Envelope glycoprotein K

GK

Family

215

false

Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) glycoprotein K (gK) plays an essential role in viral replication and cell fusion. gK is a very hydrophobic membrane protein that contains a signal sequence and several hydrophobic regions. gK contains three transmembrane domains (amino acids 125-139, 226-239, a...

[ "GO:0016020" ]

[ "membrane" ]

[ "cellular_component" ]

1

[ "PFAM" ]

[ "PF01621" ]

[ "Fusion_gly_K" ]

[ 215 ]

1

[]

0

[]

0

[ "PUB00006395" ]

[ "9407122" ]

[ "Determination of the transmembrane topology of herpes simplex virus type 1 glycoprotein K." ]

[ 1997 ]

1

[]

0

null

[ "Alphaherpesvirinae", "Pseudomonadati" ]

[ 212, 3 ]

2

[]

0

true

Family

Envelope glycoprotein K

GK

7

IPR002568

2,568

Carlavirus nucleic acid-binding protein

Carla-bd

Family

654

false

This family of carlavirus nucleic acid binding proteins includes a motif for a potential C-4 type zinc finger this has four highly conserved cysteine residues and is a conserved feature of the carlaviruses 3' terminal ORF [ ]. These proteins may function as viral transcriptional regulators. The carlavirus family includ...

[ "GO:0003676", "GO:0006355" ]

[ "nucleic acid binding", "regulation of DNA-templated transcription" ]

[ "molecular_function", "biological_process" ]

2

[ "PFAM" ]

[ "PF01623" ]

[ "Carla_C4" ]

[ 654 ]

1

[]

0

[]

0

[ "PUB00001597" ]

[ "2265707" ]

[ "The 12 kDa protein of potato virus M displays properties of a nucleic acid-binding regulatory protein." ]

[ 1990 ]

1

[]

0

null

[ "Pentapetalae", "Riboviria" ]

[ 118, 536 ]

2

[]

0

true

Family

Carlavirus nucleic acid-binding protein

Carla-bd

4

IPR002569

2,569

Peptide methionine sulphoxide reductase MsrA domain

Met_Sox_Rdtase_MsrA_dom

Domain

45,850

false

Peptide methionine sulphoxide reductase (Msr) reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, Met(O), to methionine [ ]. It is present in most living organisms, and the cognate structural gene belongs to the so-called minimum gene set [ ...

[ "GO:0008113" ]

[ "peptide-methionine (S)-S-oxide reductase activity" ]

[ "molecular_function" ]

1

[ "HAMAP", "PFAM", "NCBIFAM" ]

[ "MF_01401", "PF01625", "TIGR00401" ]

[ "MsrA", "PMSR", "msrA" ]

[ 42520, 45848, 42672 ]

3

[ "EC", "GP", "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "1.8.4.11", "GenProp0182", "GenProp0213", "R-BTA-5676934", "R-HSA-1222538", "R-HSA-5676934", "R-MMU-5676934", "R-RNO-5676934" ]

[ "EC:1.8.4.11", "GP:GenProp0182", "GP:GenProp0213", "REACTOME:R-BTA-5676934", "REACTOME:R-HSA-1222538", "REACTOME:R-HSA-5676934", "REACTOME:R-MMU-5676934", "REACTOME:R-RNO-5676934" ]

8

[ "1ff3", "1fva", "1fvg", "1nwa", "2gt3", "2iem", "2j89", "2l90", "3bqe", "3bqf", "3bqg", "3bqh", "3e0m", "3pil", "3pim", "3pin", "4d7l", "4gwb", "4lwj", "4lwk", "4lwl", "4lwm", "4u66", "4w8c", "5fa9", "6agv", "6yev", "7c13", "7e43", "7ot4" ]

30

[ "PUB00006537", "PUB00015591", "PUB00015592", "PUB00015593" ]

[ "10841552", "8994848", "8816789", "12837786" ]

[ "Thiol-disulfide exchange is involved in the catalytic mechanism of peptide methionine sulfoxide reductase.", "Complete genome sequences of cellular life forms: glimpses of theoretical evolutionary genomics.", "A minimal gene set for cellular life derived by comparison of complete bacterial genomes.", "Struct...

[ 2000, 1996, 1996, 2003 ]

4

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Imitervirales", "unclassified sequences" ]

[ 842, 35897, 8461, 2, 648 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 18, 1, 7, 9, 1, 6, 2, 1, 7, 6, 1, 1, 13 ]

13

true

Domain

Peptide methionine sulphoxide reductase MsrA domain

Met_Sox_Rdtase_MsrA_dom

9

IPR002574

2,574

M matrix/glycoprotein, coronavirus

M_CoV

Family

2,972

false

This family consists of various coronavirus matrix proteins which are transmembrane glycoproteins [ ]. The membrane (M) protein is the most abundant structural protein and defines the shape of the viral envelope. It is also regarded as the central organiser of coronavirus assembly, interacting with all other major coro...

[ "GO:0039660", "GO:0016020", "GO:0055036" ]

[ "structural constituent of virion", "membrane", "virion membrane" ]

[ "molecular_function", "cellular_component", "cellular_component" ]

3

[ "HAMAP", "PFAM", "PROFILE" ]

[ "MF_04202", "PF01635", "PS51927" ]

[ "BETA_CORONA_M", "CoV_M", "COV_M" ]

[ 495, 2963, 2952 ]

3

[ "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "GenProp1009", "R-HSA-1257604", "R-HSA-389357", "R-HSA-5218920", "R-HSA-918233", "R-HSA-9678110", "R-HSA-9679509", "R-HSA-9683612", "R-HSA-9683701", "R-HSA-9692916", "R-HSA-9694322", "R-HSA-9694594", "R-HSA-9694614", "R-HSA-9694635", "R-HSA-9705671", "R-HSA-9733458", "R-HSA-9735871",...

[ "GP:GenProp1009", "REACTOME:R-HSA-1257604", "REACTOME:R-HSA-389357", "REACTOME:R-HSA-5218920", "REACTOME:R-HSA-918233", "REACTOME:R-HSA-9678110", "REACTOME:R-HSA-9679509", "REACTOME:R-HSA-9683612", "REACTOME:R-HSA-9683701", "REACTOME:R-HSA-9692916", "REACTOME:R-HSA-9694322", "REACTOME:R-HSA-96...

19

[ "7vgr", "7vgs", "7y9b", "8ctk", "8w2e", "9ctu", "9ctw", "9exa", "9l9t", "9nz3", "9nz4", "9nz5" ]

12

[ "PUB00003985", "PUB00094065", "PUB00094066", "PUB00099876" ]

[ "6325918", "31133031", "25855243", "34580920" ]

[ "Sequence and topology of a model intracellular membrane protein, E1 glycoprotein, from a coronavirus.", "Coronavirus envelope protein: current knowledge.", "Incorporation of spike and membrane glycoproteins into coronavirus virions.", "Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the ...

[ 1984, 2019, 2015, 2021 ]

4

[]

[ "IPR042550", "IPR042551", "IPR044346", "IPR044360", "IPR044361", "IPR044362", "IPR044363" ]

0

7

0

[ "Nidovirales" ]

[ 2972 ]

1

[]

0

true

Family

M matrix/glycoprotein, coronavirus

M_CoV

4

IPR002575

2,575

Aminoglycoside phosphotransferase

Aminoglycoside_PTrfase

Domain

161,253

false

This entry consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include:- aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosp...

[]

0

[ "PFAM" ]

[ "PF01636" ]

[ "APH" ]

[ 161253 ]

1

[ "EC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "2.7.1", "R-BTA-71064", "R-DRE-71064", "R-HSA-71064", "R-HSA-77289", "R-MMU-71064", "R-MMU-77289", "R-RNO-77289" ]

[ "EC:2.7.1", "REACTOME:R-BTA-71064", "REACTOME:R-DRE-71064", "REACTOME:R-HSA-71064", "REACTOME:R-HSA-77289", "REACTOME:R-MMU-71064", "REACTOME:R-MMU-77289", "REACTOME:R-RNO-77289" ]

8

[ "1j7i", "1j7l", "1j7u", "1l8t", "1nd4", "1zyl", "2b0q", "2bkk", "2olc", "2ppq", "2pu8", "2pui", "2pul", "2pun", "2pup", "2pyw", "3ats", "3att", "3csv", "3dxp", "3dxq", "3ham", "3hav", "3i0o", "3i0q", "3i1a", "3n4t", "3n4u", "3n4v", "3q2j", "3q2m", "3sg8"...

152

[ "PUB00004379" ]

[ "2167474" ]

[ "PCR cloning of a streptomycin phosphotransferase (aphE) gene from Streptomyces griseus ATCC 12475." ]

[ 1990 ]

1

[]

[ "IPR022359", "IPR041726" ]

0

2

0

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "plasmids", "unclassified sequences" ]

[ 1000, 120933, 37782, 75, 11, 1452 ]

6

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 9, 1, 6, 2, 3, 9, 9, 3, 8, 13, 16 ]

11

true

Domain

Aminoglycoside phosphotransferase

Aminoglycoside_PTrfase

6

IPR002579

2,579

Peptide methionine sulphoxide reductase MrsB domain

Met_Sox_Rdtase_MsrB_dom

Domain

40,183

false

Peptide methionine sulphoxide reductase (Msr) reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, Met(O), to methionine [ ]. It is present in most living organisms, and the cognate structural gene belongs to the so-called minimum gene set [ ...

[ "GO:0033743" ]

[ "peptide-methionine (R)-S-oxide reductase activity" ]

[ "molecular_function" ]

1

[ "HAMAP", "PFAM", "PROFILE", "NCBIFAM" ]

[ "MF_01400", "PF01641", "PS51790", "TIGR00357" ]

[ "MsrB", "SelR", "MSRB", "" ]

[ 15857, 40100, 40073, 36405 ]

4

[ "EC", "EC", "GP", "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "1.8.4", "1.8.4.12", "GenProp0182", "GenProp0213", "R-CEL-5676934", "R-DME-5676934", "R-DRE-5676934", "R-HSA-5676934", "R-MMU-5676934", "R-RNO-5676934", "R-SSC-5676934" ]

[ "EC:1.8.4", "EC:1.8.4.12", "GP:GenProp0182", "GP:GenProp0213", "REACTOME:R-CEL-5676934", "REACTOME:R-DME-5676934", "REACTOME:R-DRE-5676934", "REACTOME:R-HSA-5676934", "REACTOME:R-MMU-5676934", "REACTOME:R-RNO-5676934", "REACTOME:R-SSC-5676934" ]

11

[ "1l1d", "2k8d", "2kv1", "2kzn", "2l1u", "3cez", "3cxk", "3e0m", "3e0o", "3hcg", "3hch", "3hci", "3hcj", "3mao", "5fa9", "6q9v", "6qa0", "6sym", "6tr8", "6z1p", "7cto", "7e43" ]

22

[ "PUB00006537", "PUB00014251", "PUB00015591", "PUB00015592" ]

[ "10841552", "11938352", "8994848", "8816789" ]

[ "Thiol-disulfide exchange is involved in the catalytic mechanism of peptide methionine sulfoxide reductase.", "The mirrored methionine sulfoxide reductases of Neisseria gonorrhoeae pilB.", "Complete genome sequences of cellular life forms: glimpses of theoretical evolutionary genomics.", "A minimal gene set f...

[ 2000, 2002, 1996, 1996 ]

4

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 631, 29845, 9175, 4, 528 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 33, 2, 11, 5, 1, 14, 6, 1, 6, 12, 1, 1, 13 ]

13

true

Domain

Peptide methionine sulphoxide reductase MrsB domain

Met_Sox_Rdtase_MsrB_dom

7

IPR002580

2,580

Herpesvirus UL24

Herpes_UL24

Family

530

false

This entry consists of the human herpes virus protein UL24 and its orthologues, which are universally present in avian, mammalian and reptilian herpes viruses. Though the functions of these proteins are not known, computational analysis suggests that they may belong to the restriction endonuclease-like fold superfamily...

[]

0

[ "PFAM" ]

[ "PF01646" ]

[ "Herpes_UL24" ]

[ 530 ]

1

[ "REACTOME", "REACTOME" ]

[ "R-HSA-9609690", "R-HSA-9610379" ]

[ "REACTOME:R-HSA-9609690", "REACTOME:R-HSA-9610379" ]

2

[]

0

[ "PUB00033393" ]

[ "16474163" ]

[ "Human herpesvirus 1 UL24 gene encodes a potential PD-(D/E)XK endonuclease." ]

[ 2006 ]

1

[]

0

null

[ "Herpesvirales", "Homo sapiens", "Pseudomonadati" ]

[ 527, 1, 2 ]

3

[ "Homo sapiens" ]

[ 1 ]

1

true

Family

Herpesvirus UL24

Herpes_UL24

2

IPR002582

2,582

Holo-[acyl carrier protein] synthase

ACPS

Family

20,332

false

Holo-acyl carrier protein synthase (ACPS) transfers the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to Ser-36 of acyl carrier protein (ACP) in Escherichia coli. This post-translational modification renders holo-ACP capable of acyl group activation via thioesterification of the cysteamine thiol of 4'-PP [...

[ "GO:0000287", "GO:0008897", "GO:0006633" ]

[ "magnesium ion binding", "holo-[acyl-carrier-protein] synthase activity", "fatty acid biosynthetic process" ]

[ "molecular_function", "molecular_function", "biological_process" ]

3

[ "HAMAP", "NCBIFAM" ]

[ "MF_00101", "TIGR00516" ]

[ "AcpS", "acpS" ]

[ 20126, 16375 ]

2

[ "EC", "GP", "METACYC", "METACYC" ]

[ "2.7.8.7", "GenProp1104", "PWY-6012", "PWY-6289" ]

[ "EC:2.7.8.7", "GP:GenProp1104", "METACYC:PWY-6012", "METACYC:PWY-6289" ]

4

[ "1f7l", "1f7t", "1f80", "1fte", "1ftf", "1fth", "2bdd", "2jbz", "2jca", "2qg8", "2uv8", "2vkz", "2was", "2wat", "2wdo", "2wds", "2wdy", "3gwm", "3h7q", "3hmj", "3hqj", "3hyk", "3ne1", "3ne3", "3ne9", "3nfd", "3qmn", "4dxe", "4hc6", "4jm7", "4v58", "4v59"...

77

[ "PUB00002924", "PUB00089646" ]

[ "7559576", "21195204" ]

[ "Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase.", "Functional analysis of a mitochondrial phosphopantetheinyl transferase (PPTase) gene pptB in Aspergillus fumigatus." ]

[ 1995, 2011 ]

2

[]

[ "IPR026025" ]

0

1

0

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 43, 17776, 2110, 403 ]

4

[ "Escherichia coli (strain K12)", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 1, 1, 1, 2 ]

4

true

Family

Holo-[acyl carrier protein] synthase

ACPS

2

IPR002583

2,583

Small ribosomal subunit protein bS20

Ribosomal_bS20

Family

25,069

false

This family consists of bacterial (and chloroplast) examples of the ribosomal small subunit protein bS20. Bacterial ribosomal protein bS20 forms part of the 30S ribosomal subunit, and interacts with 16S rRNA. Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons of the m...

[ "GO:0003723", "GO:0003735", "GO:0006412", "GO:0005840" ]

[ "RNA binding", "structural constituent of ribosome", "translation", "ribosome" ]

[ "molecular_function", "molecular_function", "biological_process", "cellular_component" ]

4

[ "HAMAP", "PFAM", "PANTHER", "NCBIFAM" ]

[ "MF_00500", "PF01649", "PTHR33398", "TIGR00029" ]

[ "Ribosomal_bS20", "Ribosomal_S20p", "", "S20" ]

[ 24338, 25025, 24017, 24987 ]

4

[]

0

[ "1fjg", "1hnw", "1hnx", "1hnz", "1hr0", "1i94", "1i95", "1i96", "1i97", "1ibk", "1ibl", "1ibm", "1j5e", "1jgo", "1jgp", "1jgq", "1ml5", "1n32", "1n33", "1n34", "1n36", "1vvj", "1vy4", "1vy5", "1vy6", "1vy7", "1xmo", "1xmq", "1xnq", "1xnr", "2e5l", "2f4v"...

1,174

[ "PUB00007068", "PUB00007069", "PUB00007070" ]

[ "11297922", "11290319", "11114498" ]

[ "Atomic structures at last: the ribosome in 2000.", "The ribosome in focus.", "The end of the beginning: structural studies of ribosomal proteins." ]

[ 2001, 2001, 2000 ]

3

[]

0

null

[ "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 23382, 1193, 494 ]

3

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 1, 3, 3 ]

4

true

Family

Small ribosomal subunit protein bS20

Ribosomal_bS20

7

IPR002586

2,586

CobQ/CobB/MinD/ParA nucleotide binding domain

CobQ/CobB/MinD/ParA_Nub-bd_dom

Domain

72,438

false

This domain is found in various cobyrinic acid a,c-diamide synthases. These include CbiA ( ) and CbiP ( ) from S. typhimurium [ ], and CobQ ( ) from R. capsulatus [ ]. These amidases catalyse amidations to various side chains of hydrogenobyrinic acid or cobyrinic acid a,c-diamide in the biosynthesis of cobalamin (vitam...

[]

0

[ "PFAM" ]

[ "PF01656" ]

[ "CbiA" ]

[ 72438 ]

1

[]

0

[ "1hyq", "3cwq", "3ea0", "3kje", "3kjg", "3kjh", "3kji", "3q9l", "3r9i", "3r9j", "4dzz", "4e03", "4e07", "4e09", "4v02", "4v03", "5u1g", "6riq" ]

18

[ "PUB00002275", "PUB00003797", "PUB00015329" ]

[ "7635831", "2149583", "8501034" ]

[ "Identification and sequence analysis of genes involved in late steps in cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus.", "A family of ATPases involved in active partitioning of diverse bacterial plasmids.", "Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimur...

[ 1995, 1990, 1993 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "plasmids", "unclassified sequences" ]

[ 4323, 66022, 1079, 65, 10, 939 ]

6

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 1, 3, 2 ]

4

true

Domain

CobQ/CobB/MinD/ParA nucleotide binding domain

CobQ/CobB/MinD/ParA_Nub-bd_dom

1

IPR002587

2,587

Myo-inositol-1-phosphate synthase

Myo-inos-1-P_Synthase

Family

13,541

false

Myo-inositol 1-phosphate synthase ( ), also known as Inositol-3-phosphate synthase 1 (INO1), is a key enzyme in myo-inositol biosynthesis pathway that catalyses the conversion of glucose 6-phosphate to 1D-myo-inositol 3-phosphate in a NAD-dependent manner [ , ]. The enzyme exists in a cytoplasmic form in a wide range o...

[ "GO:0004512", "GO:0006021", "GO:0008654" ]

[ "inositol-3-phosphate synthase activity", "inositol biosynthetic process", "phospholipid biosynthetic process" ]

[ "molecular_function", "biological_process", "biological_process" ]

3

[ "PFAM", "PIRSF", "PANTHER" ]

[ "PF07994", "PIRSF015578", "PTHR11510" ]

[ "NAD_binding_5", "Myoinos-ppht_syn", "" ]

[ 8374, 12334, 8383 ]

3

[ "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "5.5.1.4", "PWY-2301", "PWY-4661", "PWY-6372", "PWY-6580", "PWY-6664", "R-BTA-1855183", "R-DDI-1855183", "R-DME-1855183", "R-HSA-1855183", "R-MMU-1855183", "R-MTU-879299", "R-PFA-1855183", "R-RNO-1855183", "R-SCE-1855183" ]

[ "EC:5.5.1.4", "METACYC:PWY-2301", "METACYC:PWY-4661", "METACYC:PWY-6372", "METACYC:PWY-6580", "METACYC:PWY-6664", "REACTOME:R-BTA-1855183", "REACTOME:R-DDI-1855183", "REACTOME:R-DME-1855183", "REACTOME:R-HSA-1855183", "REACTOME:R-MMU-1855183", "REACTOME:R-MTU-879299", "REACTOME:R-PFA-1855183...

15

[ "1gr0", "1jkf", "1jki", "1la2", "1p1f", "1p1h", "1p1i", "1p1j", "1p1k", "1rm0", "1u1i", "1vko", "3cin", "3qvs", "3qvt", "3qvw", "3qvx", "3qw2", "6k96", "7nwr", "9f2k" ]

21

[ "PUB00005654", "PUB00006393", "PUB00101379", "PUB00106885" ]

[ "7975896", "9370339", "35725777", "35080445" ]

[ "Comparison of INO1 gene sequences and products in Candida albicans and Saccharomyces cerevisiae.", "1L-myo-inositol-1-phosphate synthase.", "Characterization of inositol lipid metabolism in gut-associated Bacteroidetes.", "Lipidomics Analysis of Outer Membrane Vesicles and Elucidation of the Inositol Phospho...

[ 1994, 1997, 2022, 2022 ]

4

[]

[ "IPR017815" ]

0

1

0

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 543, 7031, 5713, 254 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S...

[ 21, 1, 1, 9, 4, 1, 4, 3, 1, 55 ]

10

true

Family

Myo-inositol-1-phosphate synthase

Myo-inos-1-P_Synthase

5

IPR002588

2,588

Alphavirus-like methyltransferase domain

Alphavirus-like_MT_dom

Domain

9,566

false

This domain is found at the N terminus of the non-structural poly-protein of Tymoviruses, it spans the RNA methyltransferase domain of the replicase large subunit, which is a RNA-dependent RNA polymerase active in viral RNA replication [ ] is found in a wide range of ssRNA viruses (Tymovirales), including Hordeivirus, ...

[ "GO:0003723", "GO:0008174", "GO:0006396", "GO:0016556" ]

[ "RNA binding", "mRNA methyltransferase activity", "RNA processing", "mRNA modification" ]

[ "molecular_function", "molecular_function", "biological_process", "biological_process" ]

4

[ "PFAM", "PROFILE" ]

[ "PF01660", "PS51743" ]

[ "Vmethyltransf", "ALPHAVIRUS_MT" ]

[ 8533, 9298 ]

2

[ "EC", "EC", "EC", "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", ...

[ "2.1.1.-", "2.7.7", "2.7.7.48", "3.6.4.13", "PWY-1061", "PWY-2083", "PWY-3542", "PWY-4021", "PWY-4161", "PWY-4202", "PWY-5059", "PWY-5105", "PWY-5301", "PWY-5305", "PWY-5479", "PWY-5665", "PWY-5729", "PWY-5748", "PWY-5765", "PWY-5773", "PWY-5846", "PWY-5883", "PWY-5975", ...

[ "EC:2.1.1.-", "EC:2.7.7", "EC:2.7.7.48", "EC:3.6.4.13", "METACYC:PWY-1061", "METACYC:PWY-2083", "METACYC:PWY-3542", "METACYC:PWY-4021", "METACYC:PWY-4161", "METACYC:PWY-4202", "METACYC:PWY-5059", "METACYC:PWY-5105", "METACYC:PWY-5301", "METACYC:PWY-5305", "METACYC:PWY-5479", "METACYC:P...

149

[ "6z0u", "6z0v", "7dop", "7fgg", "7fgh", "7fgi", "7x01", "7y38", "8aov", "8aow", "8aox", "8apx", "8axv", "8jce" ]

14

[ "PUB00005631", "PUB00020543", "PUB00020545", "PUB00020546", "PUB00020547" ]

[ "10364504", "10982322", "1645151", "10559320", "8985362" ]

[ "The N-terminal half of the brome mosaic virus 1a protein has RNA capping-associated activities: specificity for GTP and S-adenosylmethionine.", "Helicase and capping enzyme active site mutations in brome mosaic virus protein 1a cause defects in template recruitment, negative-strand RNA synthesis, and viral RNA c...

[ 1999, 2000, 1992, 1999, 1997 ]

5

[]

0

null

[ "Bacillati", "Eukaryota", "Viruses", "viral metagenome" ]

[ 2, 60, 9503, 1 ]

4

[]

0

true

Domain

Alphavirus-like methyltransferase domain

Alphavirus-like_MT_dom

3

IPR002589

2,589

Macro domain

Macro_dom

Domain

53,905

false

The Macro or A1pp domain is a module of about 180 amino acids which can bind ADP-ribose (an NAD metabolite) or related ligands. Binding to ADP-ribose could be either covalent or non-covalent [ ]: in certain cases it is believed to bind non-covalently [ ]; while in other cases (such as Aprataxin) it appears to bind both...

[]

0

[ "PFAM", "PROFILE", "SMART" ]

[ "PF01661", "PS51154", "SM00506" ]

[ "Macro", "MACRO", "A1pp" ]

[ 49367, 52561, 46648 ]

3

[ "PROSITEDOC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACT...

[ "PDOC51154", "R-BTA-5696395", "R-BTA-5696400", "R-DRE-5696395", "R-DRE-5696400", "R-HSA-191859", "R-HSA-196807", "R-HSA-5696395", "R-HSA-5696400", "R-HSA-918233", "R-HSA-9679504", "R-HSA-9682706", "R-HSA-9682708", "R-HSA-9683439", "R-HSA-9683610", "R-HSA-9684325", "R-HSA-9692916", ...

[ "PROSITEDOC:PDOC51154", "REACTOME:R-BTA-5696395", "REACTOME:R-BTA-5696400", "REACTOME:R-DRE-5696395", "REACTOME:R-DRE-5696400", "REACTOME:R-HSA-191859", "REACTOME:R-HSA-196807", "REACTOME:R-HSA-5696395", "REACTOME:R-HSA-5696400", "REACTOME:R-HSA-918233", "REACTOME:R-HSA-9679504", "REACTOME:R-H...

28

[ "1hjz", "1njr", "1spv", "1txz", "1ty8", "1vhu", "1yd9", "1zr3", "1zr5", "2acf", "2afc", "2bfq", "2bfr", "2dx6", "2eee", "2fav", "2fg1", "2fxk", "2l8r", "2lgr", "2vri", "2x47", "2xd7", "3ejf", "3ejg", "3eke", "3eti", "3ew5", "3ewo", "3ewp", "3ewq", "3ewr"...

1,132

[ "PUB00018391", "PUB00019075", "PUB00021032", "PUB00021744", "PUB00033734", "PUB00043976", "PUB00052325", "PUB00052327", "PUB00052328", "PUB00094075", "PUB00094076" ]

[ "11343911", "10550052", "15902274", "12842467", "15965484", "16912299", "18983849", "16959969", "18172500", "21525212", "31095648" ]

[ "The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation.", "A biochemical genomics approach for identifying genes by the activity of their products.", "The macro domain is an ADP-ribose binding module.", "The crystal structure of AF1521 a protein from Archaeoglobus fulgidus...

[ 2001, 1999, 2005, 2003, 2005, 2006, 2009, 2006, 2008, 2011, 2019 ]

11

[]

[ "IPR035793", "IPR035796", "IPR044371" ]

0

3

0

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 615, 17316, 23852, 11814, 308 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 16, 1, 47, 8, 1, 38, 18, 1, 19, 37, 2, 24 ]

12

true

Domain

Macro domain

Macro_dom

7

IPR002591

2,591

Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase

Phosphodiest/P_Trfase

Family

59,048

false

This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1/alkaline phosphodiesterase I/nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulphate bonds in NAD, deoxynucleotides and nucleotide sugars [ , ]. Another member of thi...

[]

0

[ "PFAM" ]

[ "PF01663" ]

[ "Phosphodiest" ]

[ 59048 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-BTA-6798695", "R-BTA-6814848", "R-CEL-196843", "R-DRE-6798695", "R-DRE-6814848", "R-HSA-162710", "R-HSA-196843", "R-HSA-199220", "R-HSA-6798695", "R-HSA-6814848", "R-HSA-9840310", "R-MMU-162710", "R-MMU-196843", "R-MMU-6798695", "R-MMU-6814848", "R-MMU-9840310", "R-RNO-196843", ...

[ "REACTOME:R-BTA-6798695", "REACTOME:R-BTA-6814848", "REACTOME:R-CEL-196843", "REACTOME:R-DRE-6798695", "REACTOME:R-DRE-6814848", "REACTOME:R-HSA-162710", "REACTOME:R-HSA-196843", "REACTOME:R-HSA-199220", "REACTOME:R-HSA-6798695", "REACTOME:R-HSA-6814848", "REACTOME:R-HSA-9840310", "REACTOME:R-...

31

[ "1ei6", "2gsn", "2gso", "2gsu", "2rh6", "2xr9", "2xrg", "3nkm", "3nkn", "3nko", "3nkp", "3nkq", "3nkr", "3q3q", "3szy", "3szz", "3t00", "3t01", "3t02", "3wav", "3waw", "3wax", "3way", "4b56", "4gtw", "4gtx", "4gty", "4gtz", "4lqy", "4lr2", "4zg6", "4zg7"...

314

[ "PUB00001983", "PUB00002881", "PUB00002950", "PUB00002981", "PUB00087462", "PUB00087464", "PUB00097864", "PUB00097865", "PUB00100963", "PUB00151894" ]

[ "9344668", "7982964", "7730366", "8617788", "15632136", "28337824", "12176993", "29717535", "28630303", "25002587" ]

[ "Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes.", "cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases.", "Affinity purification and cDNA cloning of rat neural differentiatio...

[ 1997, 1994, 1995, 1996, 2005, 2017, 2002, 2018, 2017, 2014 ]

10

[]

[ "IPR026263", "IPR039524", "IPR039527" ]

0

3

0

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 1911, 27874, 28493, 16, 754 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 26, 14, 45, 7, 53, 38, 3, 12, 52, 4, 4, 28 ]

12

true

Family

Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase

Phosphodiest/P_Trfase

5

IPR002592

2,592

Outer capsid protein sigma-1, C-terminal domain

S1_C

Domain

174

false

This entry represents the C-terminal domain of Outer capsid protein sigma-1 from Reovirus type 1 (S1, also known as Cell attachment protein) and similar proteins from reovirales. This glycoprotein is a minor capsid protein and also determines the serotype-specific humoral immune response. Sigma 1 consist of a fibrous t...

[ "GO:0007155", "GO:0019058", "GO:0019062" ]

[ "cell adhesion", "viral life cycle", "virion attachment to host cell" ]

[ "biological_process", "biological_process", "biological_process" ]

3

[ "PFAM" ]

[ "PF01664" ]

[ "Reo_sigma1" ]

[ 174 ]

1

[]

0

[ "1kke", "2oj5", "2oj6", "3eoy", "3s6x", "3s6y", "3s6z", "4gu3", "4gu4", "4odb", "4xc5", "5mhr", "5mhs" ]

13

[ "PUB00003490", "PUB00063831", "PUB00154343" ]

[ "2398530", "21829363", "29695426" ]

[ "Sequence diversity in S1 genes and S1 translation products of 11 serotype 3 reovirus strains.", "Crystal structure of reovirus attachment protein σ1 in complex with sialylated oligosaccharides.", "Structural and Functional Features of the Reovirus σ1 Tail." ]

[ 1990, 2011, 2018 ]

3

[]

0

null

[ "Reovirales" ]

[ 174 ]

1

[]

0

true

Domain

Outer capsid protein sigma-1, C-terminal domain

S1_C

5

IPR002593

2,593

Domain of unknown function DX

DX

Domain

127

false

This domain has no known function. It is found in several Caenorhabditis proteins. The domain contains 6 conserved cysteines that probably form three disulphide bridges.

[]

0

[ "PFAM" ]

[ "PF01666" ]

[ "DX" ]

[ 127 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Caenorhabditis" ]

[ 127 ]

1

[ "Caenorhabditis elegans" ]

[ 5 ]

1

true

Domain

Domain of unknown function DX

DX

3

IPR002594

2,594

Glycoside hydrolase family 12

GH12

Family

6,881

false

Glycoside hydrolase family 12 comprises enzymes with two known activities: Endo-β-1,4-glucanase ( ) and Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase ( ). These enzymes were formerly known as cellulase family H. O-Glycosyl hydrolases ( ) are a widespread group of enzymes that hydrolyse the glycosidic bo...

[ "GO:0008810", "GO:0000272" ]

[ "cellulase activity", "polysaccharide catabolic process" ]

[ "molecular_function", "biological_process" ]

2

[ "PFAM", "PANTHER" ]

[ "PF01670", "PTHR34002" ]

[ "Glyco_hydro_12", "" ]

[ 6693, 6653 ]

2

[ "CAZY", "EC" ]

[ "GH12", "3.2.1" ]

[ "CAZY:GH12", "EC:3.2.1" ]

2

[ "1h0b", "1h8v", "1ks4", "1ks5", "1nlr", "1oa2", "1oa3", "1oa4", "1olq", "1olr", "1uu4", "1uu5", "1uu6", "1w2u", "2bw8", "2bwa", "2bwc", "2jem", "2jen", "2nlr", "3amh", "3amm", "3amn", "3amp", "3amq", "3b7m", "3o7o", "3vgi", "3vhn", "3vho", "3vhp", "3vl8"...

61

[ "PUB00004870", "PUB00005266" ]

[ "7624375", "8535779" ]

[ "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases.", "Structures and mechanisms of glycosyl hydrolases." ]

[ 1995, 1995 ]

2

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "metagenomes" ]

[ 120, 2470, 4276, 15 ]

4

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Zea mays" ]

[ 2, 1 ]

2

true

Family

Glycoside hydrolase family 12

GH12

6

IPR002596

2,596

Plasmid partition protein

Plasmid_parti

Family

663

false

This family consists of conserved hypothetical proteins from Borrelia burgdorferi (Lyme disease spirochete) and similar sequences from Borreliella and Borrelia species. Some members are putative plasmid partition proteins [ ].

[]

0

[ "NCBIFAM" ]

[ "NF033725" ]

[ "borfam_49" ]

[ 663 ]

1

[]

0

[]

0

[ "PUB00003601", "PUB00105273" ]

[ "9695920", "15150244" ]

[ "Evidence of past recombination events among the genes encoding the Erp antigens of Borrelia burgdorferi.", "The essential nature of the ubiquitous 26-kilobase circular replicon of Borrelia burgdorferi." ]

[ 1998, 2004 ]

2

[]

0

null

[ "Borreliaceae" ]

[ 663 ]

1

[]

0

true

Family

Plasmid partition protein

Plasmid_parti

8

IPR002597

2,597

Herpesvirus major envelope glycoprotein

Herpes_env

Family

515

false

This family consists of probable major envelope glycoproteins from members of the herpesviridae including Human herpesvirus 1 (HHV-1), Human cytomegalovirus (HHV-5) and Human herpesvirus 3 (HHV-3). Members of the herpesviridae have a dsDNA genome and do not have an RNA stage during their replication.

[ "GO:0019031" ]

[ "viral envelope" ]

[ "cellular_component" ]

1

[ "PFAM", "PROFILE" ]

[ "PF01673", "PS51988" ]

[ "Herpes_env", "HERPESVIRUS_UL32" ]

[ 515, 515 ]

2

[ "REACTOME" ]

[ "R-HSA-9610379" ]

[ "REACTOME:R-HSA-9610379" ]

1

[ "6xf9", "6xfa" ]

2

[]

0

[]

0

null

[ "Herpesvirales", "Homo sapiens" ]

[ 514, 1 ]

2

[ "Homo sapiens" ]

[ 1 ]

1

true

Family

Herpesvirus major envelope glycoprotein

Herpes_env

7

IPR002600

2,600

Herpesvirus UL7-like

Herpes_UL7

Family

334

false

This family consists of various functionally undefined proteins from the herpesviridae and UL7 from Bovine herpesvirus 1 [ , ]. UL7 is not essential for virus replication in cell culture, and is found localized in the cytoplasm of infected cells accumulated around the nucleus but could not be detected in purified virio...

[]

0

[ "HAMAP", "PFAM" ]

[ "MF_04038", "PF01677" ]

[ "HSV_CEP1", "Herpes_UL7" ]

[ 310, 334 ]

2

[ "REACTOME", "REACTOME" ]

[ "R-HSA-9609690", "R-HSA-9610379" ]

[ "REACTOME:R-HSA-9609690", "REACTOME:R-HSA-9610379" ]

2

[ "6lqn", "6lqo", "6t5a" ]

3

[ "PUB00003518", "PUB00005609", "PUB00082595", "PUB00084208" ]

[ "8551568", "7793062", "21345947", "24899189" ]

[ "Identification and characterization of the bovine herpesvirus 1 UL7 gene and gene product which are not essential for virus replication in cell culture.", "Nucleotide sequence analysis of a 30-kb region of the bovine herpesvirus 1 genome which exhibits a colinear gene arrangement with the UL21 to UL4 genes of he...

[ 1996, 1995, 2011, 2014 ]

4

[]

0

null

[ "Homo sapiens", "Orthoherpesviridae" ]

[ 1, 333 ]

2

[ "Homo sapiens" ]

[ 1 ]

1

true

Family

Herpesvirus UL7-like

Herpes_UL7

5

IPR002602

2,602

Domain of unknown function DB

DB

Domain

3,003

false

This domain has no known function being found in several Caenorhabditis elegans proteins. The domain contains 12 conserved cysteines that probably form six disulphide bridges. This domain is found associated with Ig and Fibronectin, type III domains.

[]

0

[ "PFAM" ]

[ "PF01682" ]

[ "DB" ]

[ 3003 ]

1

[ "REACTOME" ]

[ "R-CEL-114608" ]

[ "REACTOME:R-CEL-114608" ]

1

[]

0

[]

0

[]

0

null

[ "Bilateria" ]

[ 3003 ]

1

[ "Caenorhabditis elegans", "Drosophila melanogaster" ]

[ 30, 5 ]

2

true

Domain

Domain of unknown function DB

DB

6

IPR002603

2,603

ET repeat

ET_repeat

Repeat

168

false

This repeat is found in proteins of unknown function, mainly from Caenorhabditis. Each repeat contains 8-10 conserved cysteines that probably form 4-5 disulphide bridges. By inspection of the conservation of cysteines it looks like cysteines 1, 2, 3, 4, 9 and 10 are always present and that sometimes the pair 5 and 8 or...

[]

0

[ "PFAM" ]

[ "PF01684" ]

[ "ET" ]

[ 168 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Rhabditida" ]

[ 168 ]

1

[ "Caenorhabditis elegans" ]

[ 2 ]

1

true

Repeat

ET repeat

ET_repeat

5

IPR002605

2,605

Adenovirus penton base protein

Adeno_Penton_B

Family

1,442

false

This family consists of various adenovirus penton base proteins (also known as Protein III) [ ], from both the mastadenoviridae having mammalian hosts and the aviadenoviridae having avian hosts. The penton base is a major structural protein forming part of the penton which consists of a base and a fibre, the pentons ho...

[ "GO:0075509", "GO:0039623" ]

[ "endocytosis involved in viral entry into host cell", "T=25 icosahedral viral capsid" ]

[ "biological_process", "cellular_component" ]

2

[ "HAMAP", "PFAM" ]

[ "MF_04052", "PF01686" ]

[ "ADV_CAPSP", "Adeno_Penton_B" ]

[ 691, 1442 ]

2

[]

0

[ "1x9p", "1x9t", "2c6s", "2c9f", "2c9g", "3izo", "3zif", "4aqq", "4ar2", "4v4u", "6b1t", "6cgv", "6hcr", "6qi5", "6yba", "6z7n", "6z7q", "7rd1", "7s78", "7tau", "8c9n", "8coi", "8qb3", "8qbx", "8roq", "9lr9" ]

26

[ "PUB00005586", "PUB00076673", "PUB00087145" ]

[ "1316685", "20798312", "20615244" ]

[ "Characterization of the avian adenovirus penton base.", "Atomic structure of human adenovirus by cryo-EM reveals interactions among protein networks.", "Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells." ]

[ 1992, 2010, 2010 ]

3

[]

0

null

[ "Adenoviridae", "Mycobacterium simiae" ]

[ 1441, 1 ]

2

[]

0

true

Family

Adenovirus penton base protein

Adeno_Penton_B

9

IPR002606

2,606

Riboflavin kinase, bacterial

Riboflavin_kinase_bac

Family

24,458

false

Riboflavin is converted into catalytically active cofactors (FAD and FMN) by the actions of riboflavin kinase ( ), which converts it into FMN, and FAD synthetase ( ), which adenylates FMN to FAD. Eukaryotes usually have two separate enzymes, while most prokaryotes have a single bifunctional protein that can carry out b...

[ "GO:0003919", "GO:0008531", "GO:0009231" ]

[ "FMN adenylyltransferase activity", "riboflavin kinase activity", "riboflavin biosynthetic process" ]

[ "molecular_function", "molecular_function", "biological_process" ]

3

[ "PIRSF", "NCBIFAM" ]

[ "PIRSF004491", "TIGR00083" ]

[ "FAD_Synth", "ribF" ]

[ 24111, 23840 ]

2

[ "EC", "EC", "GP", "METACYC", "METACYC", "METACYC", "METACYC" ]

[ "2.7.1.26", "2.7.7.2", "GenProp1734", "PWY-5523", "PWY-6167", "PWY-6168", "PWY-7863" ]

[ "EC:2.7.1.26", "EC:2.7.7.2", "GP:GenProp1734", "METACYC:PWY-5523", "METACYC:PWY-6167", "METACYC:PWY-6168", "METACYC:PWY-7863" ]

7

[ "1mrz", "1s4m", "1t6x", "1t6y", "1t6z", "2i1l", "2x0k", "3op1", "3zug", "4uze", "4uzf", "5fnz", "5fo0", "5fo1" ]

14

[ "PUB00010127", "PUB00030175", "PUB00035657" ]

[ "12517446", "14580199", "17049878" ]

[ "A conserved domain in prokaryotic bifunctional FAD synthetases can potentially catalyze nucleotide transfer.", "Ligand binding-induced conformational changes in riboflavin kinase: structural basis for the ordered mechanism.", "Over-expression in Escherichia coli, purification and characterization of isoform 2 ...

[ 2003, 2003, 2007 ]

3

[ "IPR023468" ]

[]

1

0

1

[ "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 23976, 28, 454 ]

3

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Family

Riboflavin kinase, bacterial

Riboflavin_kinase_bac

7

IPR002608

2,608

Paramyxovirus non-structural protein C

Paramyxo_C

Family

233

false

This family consist of the C proteins (C', C, Y1, Y2) found in the Paramyxovirinae, e.g. Human parainfluenza virus 3, and Sendai virus. The C proteins effect viral RNA synthesis having both a positive and negative effect during the course of infection [ ]. The paramyxovirinae have a negative-strand ssRNA genome of 15.3...

[ "GO:0052031" ]

[ "symbiont-mediated perturbation of host defense response" ]

[ "biological_process" ]

1

[ "PFAM" ]

[ "PF01692" ]

[ "Paramyxo_C" ]

[ 233 ]

1

[]

0

[ "3wwt", "6kp3" ]

2

[ "PUB00001182", "PUB00003545" ]

[ "2542021", "9621061" ]

[ "Scanning independent ribosomal initiation of the Sendai virus Y proteins in vitro and in vivo.", "The various Sendai virus C proteins are not functionally equivalent and exert both positive and negative effects on viral RNA accumulation during the course of infection." ]

[ 1989, 1998 ]

2

[]

0

null

[ "Respirovirus" ]

[ 233 ]

1

[]

0

true

Family

Paramyxovirus non-structural protein C

Paramyxo_C

8

IPR002610

2,610

Peptidase S54, RHOMBOID-like

Peptidase_S54_rhomboid-like

Family

7,635

false

This group of proteins contain serine peptidases belonging to the MEROPS peptidase family S54 (Rhomboid, clan ST). They are integral membrane proteins related to the Drosophila melanogaster (Fruit fly) rhomboid protein . Members of this family are found in bacteria, archaea, and eukaryotes, mainly plant and fungi. Plan...

[ "GO:0006508", "GO:0016020" ]

[ "proteolysis", "membrane" ]

[ "biological_process", "cellular_component" ]

2

[ "PANTHER" ]

[ "PTHR22936" ]

[ "" ]

[ 7635 ]

1

[ "EC" ]

[ "3.4.21.105" ]

[ "EC:3.4.21.105" ]

1

[]

0

[ "PUB00152817", "PUB00152819" ]

[ "22007993", "35682638" ]

[ "Rhomboid proteases in plants - still in square one?", "<i>KOMPEITO</i>, an Atypical <i>Arabidopsis</i> Rhomboid-Related Gene, Is Required for Callose Accumulation and Pollen Wall Development." ]

[ 2012, 2022 ]

2

[]

[ "IPR017092" ]

0

1

0

[ "Archaea", "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 19, 600, 7010, 6 ]

4

[ "Arabidopsis thaliana", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 32, 1, 22, 45 ]

4

true

Family

Peptidase S54, RHOMBOID-like

Peptidase_S54_rhomboid-like

5

IPR002611

2,611

IstB-like ATP-binding domain

IstB_ATP-bd

Domain

33,281

false

Proteins in this entry contain an ATP/GTP binding P-loop motif, including the DNA replication protein DnaC and IS21 transposase regulator IstB, which are close paralogues [ , , ]. DnaC interacts with DnaB and form a primosome complex for DNA replication [ , ].

[ "GO:0005524" ]

[ "ATP binding" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF01695" ]

[ "IstB_IS21" ]

[ 33281 ]

1

[]

0

[ "3ec2", "3ecc", "5bq5", "6qel", "6qem", "8q3w", "8q4d" ]

7

[ "PUB00001737", "PUB00001854", "PUB00068110", "PUB00105619", "PUB00151011" ]

[ "9141667", "7698671", "2844800", "26276634", "30797687" ]

[ "Characterization of IS1474, an insertion sequence of the IS21 family isolated from Pseudomonas alcaligenes NCIB 9867.", "Characterization and sequence of a novel insertion sequence, IS1162, from Pseudomonas fluorescens.", "Operon structure of dnaT and dnaC genes essential for normal and stable DNA replication ...

[ 1997, 1995, 1988, 2015, 2019 ]

5

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "other sequences", "unclassified sequences" ]

[ 126, 31859, 103, 396, 7, 790 ]

6

[ "Escherichia coli (strain K12)" ]

[ 2 ]

1

true

Domain

IstB-like ATP-binding domain

IstB_ATP-bd

4

IPR002612

2,612

Adenovirus large t-antigen, E1B 55kDa protein

Adeno_E1B_55kDa

Family

478

false

This family consists of adenovirus E1B 55kDa protein or large t-antigen. E1B 55kDa binds p53 the tumor suppressor protein converting it from a transcriptional activator which responds to damaged DNA in to an unregulated repressor of genes with a p53 binding site [ ]. This protects the virus against p53 induced host ant...

[]

0

[ "PFAM" ]

[ "PF01696" ]

[ "Adeno_E1B_55K" ]

[ 478 ]

1

[]

0

[ "5g5n", "5g5o", "6qi5" ]

3

[ "PUB00003708" ]

[ "10207064" ]

[ "Corepressor required for adenovirus E1B 55,000-molecular-weight protein repression of basal transcription." ]

[ 1999 ]

1

[]

0

null

[ "Adenoviridae", "Bacteria", "Bodo saltans" ]

[ 451, 26, 1 ]

3

[]

0

true

Family

Adenovirus large t-antigen, E1B 55kDa protein

Adeno_E1B_55kDa

3

IPR002614

2,614

Inner layer core protein VP3, Orbivirus

Inner_layer_core_VP3_Orbivir

Family

944

false

This entry represents the inner layer core protein VP3 from Orbiviruses, a family of Reoviruses that have dsRNA genomes of 10-12 linear segments [ ]. Orbiviruses include Broadhaven virus (BRD), Epizootic hemorrhagic disease virus and Bluetongue virus (BTV) [ ]. The Orbivirus VP3 protein is part of the virus core and ma...

[ "GO:0005198" ]

[ "structural molecule activity" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF01700" ]

[ "Orbi_VP3" ]

[ 944 ]

1

[ "GP" ]

[ "GenProp1006" ]

[ "GP:GenProp1006" ]

1

[ "2btv", "6pns", "6po2", "8w12", "8w19", "8w1c", "8w1i", "8w1o", "8w1r", "8w1s" ]

10

[ "PUB00003147", "PUB00004287" ]

[ "1328474", "9774103" ]

[ "Comparison of the major structural core proteins of tick-borne and Culicoides-borne orbiviruses.", "The atomic structure of the bluetongue virus core." ]

[ 1992, 1998 ]

2

[]

0

null

[ "Neoptera", "Riboviria" ]

[ 7, 937 ]

2

[]

0

true

Family

Inner layer core protein VP3, Orbivirus

Inner_layer_core_VP3_Orbivir

5

IPR002615

2,615

Photosystem I PsaJ, reaction centre subunit IX

PSI_PsaJ

Family

13,739

false

This family consists of the photosystem I reaction centre subunit IX or PsaJ from various organisms including Synechocystis sp. (strain PCC 6803), Pinus thunbergii (Japanese black pine) and Zea mays (Maize). PsaJ ( ) is a small 4.4kDa, chloroplast encoded, hydrophobic subunit of the photosystem I reaction complex whose...

[ "GO:0015979", "GO:0009522" ]

[ "photosynthesis", "photosystem I" ]

[ "biological_process", "cellular_component" ]

2

[ "HAMAP", "PFAM", "PANTHER" ]

[ "MF_00522", "PF01701", "PTHR36082" ]

[ "PSI_PsaJ", "PSI_PsaJ", "" ]

[ 13579, 13737, 13578 ]

3

[ "GP", "GP" ]

[ "GenProp0660", "GenProp1353" ]

[ "GP:GenProp0660", "GP:GenProp1353" ]

2

[ "1jb0", "2o01", "2wsc", "2wse", "2wsf", "3lw5", "3pcq", "4fe1", "4kt0", "4l6v", "4rku", "4xk8", "4y28", "5l8r", "5oy0", "5zf0", "5zgb", "5zgh", "5zji", "6fos", "6hqb", "6igz", "6ijj", "6ijo", "6jeo", "6jo5", "6jo6", "6k33", "6k61", "6kif", "6kig", "6l35"...

138

[ "PUB00000458", "PUB00152828" ]

[ "10220342", "33846594" ]

[ "A large fraction of PsaF is nonfunctional in photosystem I complexes lacking the PsaJ subunit.", "Structural insights into photosystem II assembly." ]

[ 1999, 2021 ]

2

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "marine sediment metagenome" ]

[ 415, 13318, 5, 1 ]

4

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 4, 4, 2 ]

3

true

Family

Photosystem I PsaJ, reaction centre subunit IX

PSI_PsaJ

3

IPR002616

2,616

tRNA-guanine(15) transglycosylase-like

tRNA_ribo_trans-like

Domain

33,769

false

Queuine tRNA-ribosyltransferases, also known as tRNA-guanine transglycosylases (TGT) , modify tRNAs for asparagine, aspartic acid, histidine and tyrosine with queuine at position 34 and with archaeosine at position 15 in archaeal tRNAs. In bacteria it catalyses the exchange of guanine-34 at the wobble position with 7-a...

[ "GO:0006400" ]

[ "tRNA modification" ]

[ "biological_process" ]

1

[ "PFAM", "NCBIFAM" ]

[ "PF01702", "TIGR00449" ]

[ "TGT", "tgt_general" ]

[ 33767, 32103 ]

2

[ "EC", "EC", "METACYC", "METACYC", "REACTOME" ]

[ "2.4.2", "2.4.2.29", "PWY-6700", "PWY-8106", "R-HSA-6782315" ]

[ "EC:2.4.2", "EC:2.4.2.29", "METACYC:PWY-6700", "METACYC:PWY-8106", "REACTOME:R-HSA-6782315" ]

5

[ "1efz", "1enu", "1f3e", "1iq8", "1it7", "1it8", "1j2b", "1k4g", "1k4h", "1n2v", "1ozm", "1ozq", "1p0b", "1p0d", "1p0e", "1pud", "1pxg", "1q2r", "1q2s", "1q4w", "1q63", "1q65", "1q66", "1r5y", "1s38", "1s39", "1wkd", "1wke", "1wkf", "1y5v", "1y5w", "1y5x"...

192

[ "PUB00001287", "PUB00003305", "PUB00082327", "PUB00101146", "PUB00101147" ]

[ "8654383", "8323579", "11255023", "30159947", "26929322" ]

[ "Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.", "tRNA-guanine transglycosylase from Escherichia coli. Overexpression, purification and quaternary structure.", "Characterization of cDNA encoding the human tRNA-guanine transglycosylase (TGT) catalytic subunit.", "Identi...

[ 1996, 1993, 2001, 2018, 2016 ]

5

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified Caudoviricetes", "unclassified sequences" ]

[ 1570, 22449, 9023, 8, 719 ]

5

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Schizosaccharomyces po...

[ 2, 4, 2, 1, 9, 6, 3, 6, 9, 2, 27 ]

11

true

Domain

tRNA-guanine(15) transglycosylase-like

tRNA_ribo_trans-like

4

IPR002618

2,618

UDPGP family

UDPGP_fam

Family

19,012

false

This family contains UTP--glucose-1-phosphate uridylyltransferases ( ), UDP-sugar pyrophosphorylases ( ), UDP-N-acetylglucosamine pyrophosphorylases ( ) and UDP-N-acetylhexosamine pyrophosphorylases, all of which catalyse the transfer of an uridylyl group.

[ "GO:0070569" ]

[ "uridylyltransferase activity" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF01704" ]

[ "UDPGP" ]

[ 19012 ]

1

[ "EC", "GP", "GP", "GP", "GP", "GP", "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "2.7.7", "GenProp1222", "GenProp1330", "GenProp1347", "GenProp1459", "GenProp1639", "GenProp1743", "R-BTA-173599", "R-BTA-3322077", "R-CEL-446210", "R-DDI-173599", "R-DDI-3322077", "R-DDI-446210", "R-HSA-173599", "R-HSA-3322077", "R-HSA-446210", "R-MMU-173599", "R-MMU-3322077", "...

[ "EC:2.7.7", "GP:GenProp1222", "GP:GenProp1330", "GP:GenProp1347", "GP:GenProp1459", "GP:GenProp1639", "GP:GenProp1743", "REACTOME:R-BTA-173599", "REACTOME:R-BTA-3322077", "REACTOME:R-CEL-446210", "REACTOME:R-DDI-173599", "REACTOME:R-DDI-3322077", "REACTOME:R-DDI-446210", "REACTOME:R-HSA-17...

25

[ "1jv1", "1jv3", "1jvd", "1jvg", "1vm8", "1z90", "2i5k", "2icx", "2icy", "2oef", "2oeg", "2q4j", "2yqc", "2yqh", "2yqj", "2yqs", "3gue", "3oc9", "3ogz", "3oh0", "3oh1", "3oh2", "3oh3", "3oh4", "3r2w", "3r3i", "4bma", "4bqh", "4j18", "4m28", "4m2a", "4m2b"...

57

[]

0

[]

[ "IPR016267", "IPR039741" ]

0

2

0

[ "Bacteria", "Eukaryota", "Klosneuvirinae", "metagenomes" ]

[ 2123, 16841, 4, 44 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 28, 8, 11, 8, 22, 10, 2, 19, 13, 3, 3, 107 ]

12

true

Family

UDPGP family

UDPGP_fam

1

IPR002619

2,619

Domain of unknown function CX

CX

Domain

735

false

This domain of unknown function is found in proteins from nematodes, including Uncharacterized protein C07A9.12 from Caenorhabditis elegans. The domain contains 6 conserved cysteines that probably form three disulphide bridges.

[]

0

[ "PFAM" ]

[ "PF01705" ]

[ "CX" ]

[ 735 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Nematoda" ]

[ 735 ]

1

[ "Caenorhabditis elegans" ]

[ 25 ]

1

true

Domain

Domain of unknown function CX

CX

6

IPR002620

2,620

Alphavirus nsp2 protease domain

Alphavirus_nsp2pro

Domain

1,840

false

The family of alphaviruses includes 26 known members. They infect a variety of hosts including mosquitoes, birds, rodents and other mammals with worldwide distribution. Alphaviruses also pose a potential threat to human health in many area. For example, Venezuelan Equine Encephalitis Virus (VEEV) causes encephalitis in...

[]

0

[ "PFAM", "PROFILE" ]

[ "PF01707", "PS51520" ]

[ "Peptidase_C9", "NSP2PRO" ]

[ 1797, 1830 ]

2

[ "EC", "EC", "EC", "EC", "EC", "EC", "EC", "EC", "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC",...

[ "2.1.1.-", "2.7.7.-", "2.7.7.19", "2.7.7.48", "3.1.3.84", "3.4.22.-", "3.6.1.15", "3.6.1.74", "3.6.4.13", "PWY-1061", "PWY-2083", "PWY-3542", "PWY-4021", "PWY-4161", "PWY-4202", "PWY-5059", "PWY-5105", "PWY-5301", "PWY-5305", "PWY-5479", "PWY-5665", "PWY-5729", "PWY-5748"...

[ "EC:2.1.1.-", "EC:2.7.7.-", "EC:2.7.7.19", "EC:2.7.7.48", "EC:3.1.3.84", "EC:3.4.22.-", "EC:3.6.1.15", "EC:3.6.1.74", "EC:3.6.4.13", "METACYC:PWY-1061", "METACYC:PWY-2083", "METACYC:PWY-3542", "METACYC:PWY-4021", "METACYC:PWY-4161", "METACYC:PWY-4202", "METACYC:PWY-5059", "METACYC:PW...

175

[ "2hwk", "3trk", "4gua", "4ztb", "5ezq", "5ezs", "6bcm", "6jim", "7y38", "8duf", "8t8n" ]

11

[ "PUB00011704", "PUB00020025", "PUB00030423", "PUB00041527", "PUB00055516", "PUB00076953" ]

[ "11517925", "9891971", "14725770", "16962975", "19013248", "7044372" ]

[ "Evolutionary lines of cysteine peptidases.", "Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases.", "The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall.", ...

[ 2001, 1998, 2004, 2006, 2009, 1982 ]

6

[]

0

null

[ "Alphavirus", "Bacteria", "Eukaryota", "Halopenitus malekzadehii" ]

[ 1806, 21, 12, 1 ]

4

[ "Oryza sativa subsp. japonica", "Zea mays" ]

[ 1, 1 ]

2

true

Domain

Alphavirus nsp2 protease domain

Alphavirus_nsp2pro

1

IPR002621

2,621

Geminivirus infecting protein

Gemini_mov

Family

503

false

This family consists of putative movement proteins from Maize streak virus and Wheat dwarf virus [ ].

[ "GO:0046740", "GO:0016020" ]

[ "transport of virus in host, cell to cell", "membrane" ]

[ "biological_process", "cellular_component" ]

2

[ "PFAM" ]

[ "PF01708" ]

[ "Gemini_mov" ]

[ 503 ]

1

[]

0

[]

0

[ "PUB00034766" ]

[ "3947330" ]

[ "Sequence homology between the coat proteins of DNA and RNA plant viruses." ]

[ 1986 ]

1

[]

0

null

[ "Aldrovandia affinis", "Mastrevirus" ]

[ 1, 502 ]

2

[]

0

true

Family

Geminivirus infecting protein

Gemini_mov

2

IPR002622

2,622

Transposase, Synechocystis PCC 6803

Transposase_14

Domain

2,911

false

Transposase proteins are necessary for efficient DNA transposition. This entry includes insertion sequences from Synechocystis sp. (strain PCC 6803) three of which are characterised as homologous to bacterial IS5- and IS4- and to several members of the IS630-Tc1-mariner superfamily [ ].

[]

0

[ "PFAM" ]

[ "PF01710" ]

[ "HTH_Tnp_IS630" ]

[ 2911 ]

1

[]

0

[]

0

[ "PUB00001874" ]

[ "9305771" ]

[ "Three insertion sequences from the cyanobacterium Synechocystis PCC6803 support the occurrence of horizontal DNA transfer among bacteria." ]

[ 1997 ]

1

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "metagenomes" ]

[ 9, 2801, 86, 5, 10 ]

5

[]

0

true

Domain

Transposase, Synechocystis PCC 6803

Transposase_14

8

IPR002624

2,624

Deoxynucleoside kinase

DCK/DGK

Family

12,426

false

This family consists of various deoxynucleoside kinases including cytidine ( ), guanosine ( ), adenosine ( ) and thymidine kinase ( ), which also phosphorylates deoxyuridine and deoxycytosine. These enzymes catalyse the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside, using ATP and yielding ADP in...

[ "GO:0005524", "GO:0019136", "GO:0006139" ]

[ "ATP binding", "deoxynucleoside kinase activity", "nucleobase-containing compound metabolic process" ]

[ "molecular_function", "molecular_function", "biological_process" ]

3

[ "PIRSF" ]

[ "PIRSF000705" ]

[ "DNK" ]

[ 12426 ]

1

[ "EC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "2.7.1", "R-BTA-73614", "R-BTA-74217", "R-DME-73614", "R-HSA-73614", "R-HSA-74217", "R-MMU-73614", "R-MMU-74217", "R-RNO-73614", "R-RNO-74217" ]

[ "EC:2.7.1", "REACTOME:R-BTA-73614", "REACTOME:R-BTA-74217", "REACTOME:R-DME-73614", "REACTOME:R-HSA-73614", "REACTOME:R-HSA-74217", "REACTOME:R-MMU-73614", "REACTOME:R-MMU-74217", "REACTOME:R-RNO-73614", "REACTOME:R-RNO-74217" ]

10

[ "1j90", "1oe0", "1ot3", "1p5z", "1p60", "1p61", "1p62", "1zm7", "1zmx", "2a2z", "2a30", "2a7q", "2jaq", "2jas", "2jat", "2jcs", "2jj8", "2no0", "2no1", "2no6", "2no7", "2no9", "2noa", "2ocp", "2qrn", "2qro", "2vp0", "2vp2", "2vp4", "2vp5", "2vp6", "2vp9"...

79

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "metagenomes" ]

[ 9027, 2939, 171, 289 ]

4

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 5, 2, 13, 9, 10 ]

5

true

Family

Deoxynucleoside kinase

DCK/DGK

9

IPR002625

2,625

Smr domain

Smr_dom

Domain

39,445

false

The Smr domain is an around 90-residue domain found in: The C-terminal region of the MutS2 proteins from bacteria and plants, such as Endonuclease MutS2 from Bacillus thuringiensis. The small MutS related (Smr) proteins from bacteria and eukaryotes, including Ribosome rescue factor SmrB from Escherichia coli. Other Smr...

[]

0

[ "PFAM", "PROFILE", "SMART" ]

[ "PF01713", "PS50828", "SM00463" ]

[ "Smr", "SMR", "SMR" ]

[ 29847, 37485, 32352 ]

3

[ "PROSITEDOC" ]

[ "PDOC50828" ]

[ "PROSITEDOC:PDOC50828" ]

1

[ "2d9i", "2vkc", "2zqe", "3fau", "3qd7", "4och", "4od6", "7qgn", "7qgr", "7qv3", "8qpp", "8r55", "8r5o", "8r6s", "8ras", "8rdj", "8w9z", "8wa0", "8wa1", "9epc" ]

20

[ "PUB00005494", "PUB00018300", "PUB00060369" ]

[ "10431172", "10973051", "12730195" ]

[ "Smr: a bacterial and eukaryotic homologue of the C-terminal region of the MutS2 family.", "Dual recognition-incision enzymes might be involved in mismatch repair and meiosis.", "Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination." ]

[ 1999, 2000, 2003 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Caudoviricetes", "Eukaryota", "unclassified sequences" ]

[ 16, 24073, 4, 14968, 384 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 52, 6, 3, 2, 2, 3, 1, 3, 40, 4, 2, 2, 61 ]

13

true

Domain

Smr domain

Smr_dom

3

IPR002629

2,629

Cobalamin-independent methionine synthase MetE, C-terminal/archaeal

Met_Synth_C/arc

Domain

34,598

false

Methionine synthases catalyse the the final step of methionine biosynthesis. Two apparently unrelated families of proteins catalyse this step: cobalamin-dependent methionine synthase, which catalyses the transfer of a methyl group from N5-methyltetrahydrofolate to L-homocysteine and requires cobalamin as a cofactor (Me...

[ "GO:0003871", "GO:0008270" ]

[ "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity", "zinc ion binding" ]

[ "molecular_function", "molecular_function" ]

2

[ "PFAM", "CDD" ]

[ "PF01717", "cd03311" ]

[ "Meth_synt_2", "CIMS_C_terminal_like" ]

[ 33843, 30143 ]

2

[ "EC", "METACYC", "METACYC", "METACYC", "METACYC" ]

[ "2.1.1.14", "PWY-5041", "PWY-6151", "PWY-6936", "PWY-702" ]

[ "EC:2.1.1.14", "METACYC:PWY-5041", "METACYC:PWY-6151", "METACYC:PWY-6936", "METACYC:PWY-702" ]

5

[ "1t7l", "1u1h", "1u1j", "1u1u", "1u22", "1xdj", "1xpg", "1xr2", "1ypx", "2nq5", "3bq5", "3bq6", "3l7r", "3ppc", "3ppf", "3ppg", "3pph", "3rpd", "3t0c", "4l5z", "4l61", "4l64", "4l65", "4l6h", "4l6o", "4qqu", "4ztx", "4zty" ]

28

[ "PUB00037682", "PUB00070291", "PUB00070292" ]

[ "15630480", "1339288", "10469143" ]

[ "Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved by gene duplication.", "Comparison of cobalamin-independent and cobalamin-dependent methionine synthases from Escherichia coli: two solutions to the same chemical problem.", "Methylcobalamin:homocysteine methyltransfera...

[ 2005, 1992, 1999 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences", "uncultured virus" ]

[ 867, 26415, 6993, 322, 1 ]

5

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]

[ 12, 1, 3, 9, 1, 1, 19 ]

7

true

Domain

Cobalamin-independent methionine synthase MetE, C-terminal/archaeal

Met_Synth_C/arc

9

IPR002630

2,630

Orbivirus non-structural protein NS1/hydrophobic tubular protein

Orbi_NS1

Family

878

false

This family consists of orbivirus non-structural protein NS1, or hydrophobic tubular protein. NS1 has no specific function in virus replication, it is however thought to play a role in transport of mature virus particles from virus inclusion bodies to the cell membrane [ ]. Orbivirus are part of the larger reoviridae w...

[]

0

[ "PFAM" ]

[ "PF01718" ]

[ "Orbi_NS1" ]

[ 878 ]

1

[ "GP" ]

[ "GenProp1006" ]

[ "GP:GenProp1006" ]

1

[ "6n9y" ]

1

[ "PUB00003168" ]

[ "9152425" ]

[ "Characterization of tubular structures composed of nonstructural protein NS1 of African horsesickness virus expressed in insect cells." ]

[ 1997 ]

1

[]

0

null

[ "Riboviria" ]

[ 878 ]

1

[]

0

true

Family

Orbivirus non-structural protein NS1/hydrophobic tubular protein

Orbi_NS1

5

IPR002631

2,631

Plasmid replication protein, origin binding domain

Plasmid_rep_OBD

Domain

1,056

false

This entry represents the N-terminal origin binding domain (OBD) of various bacterial plasmid replication (Rep) proteins. Rep is a rolling-circle replication (RCR) initiation protein and provides endonuclease activity. It is generally found as hexamer, in contrast to other RCR proteins that are purified as monomers or ...

[ "GO:0003677", "GO:0003916", "GO:0006260", "GO:0005727" ]

[ "DNA binding", "DNA topoisomerase activity", "DNA replication", "extrachromosomal circular DNA" ]

[ "molecular_function", "molecular_function", "biological_process", "cellular_component" ]

4

[ "PFAM" ]

[ "PF01719" ]

[ "Rep_OBD" ]

[ 1056 ]

1

[]

0

[ "3dkx", "3dky", "4u87", "8amt", "8amu", "8amv" ]

6

[ "PUB00001783", "PUB00097405" ]

[ "2695401", "26875695" ]

[ "Characterization of a cryptic plasmid from Lactobacillus plantarum.", "Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158." ]

[ 1989, 2016 ]

2

[]

0

null

[ "Bacteria", "Ecdysozoa", "Inoviridae", "unclassified sequences" ]

[ 990, 5, 6, 55 ]

4

[]

0

true

Domain

Plasmid replication protein, origin binding domain

Plasmid_rep_OBD

9

IPR002633

2,633

Bacteriocin, class IIa

Bacteriocin_IIa

Family

270

false

Many Gram-positive bacteria produce ribosomally synthesized antimicrobial peptides, often termed bacteriocins. One important and well studied class of bacteriocins is the class IIa or pediocin-like bacteriocins produced by lactic acid bacteria. All class IIa bacteriocins are produced by food-associated strains, isolate...

[ "GO:0042742", "GO:0005576" ]

[ "defense response to bacterium", "extracellular region" ]

[ "biological_process", "cellular_component" ]

2

[ "PFAM" ]

[ "PF01721" ]

[ "Bacteriocin_II" ]

[ 270 ]

1

[ "PROSITEDOC" ]

[ "PDOC60030" ]

[ "PROSITEDOC:PDOC60030" ]

1

[ "1cw5", "1cw6", "1og7", "1ohm", "1ohn", "1ry3", "2a2b", "2leu", "2ljq", "2n4k", "3leu", "5ukz", "7vly", "7xno", "7xtg" ]

15

[ "PUB00033828", "PUB00033829", "PUB00033830" ]

[ "16232543", "15611086", "16059970" ]

[ "Class IIa bacteriocins from lactic acid bacteria: antibacterial activity and food preservation.", "The C-terminal domain of pediocin-like antimicrobial peptides (class IIa bacteriocins) is involved in specific recognition of the C-terminal part of cognate immunity proteins and in determining the antimicrobial sp...

[ 1999, 2005, 2005 ]

3

[]

0

null

[ "Bacteria", "uncultured prokaryote" ]

[ 268, 2 ]

2

[]

0

true

Family

Bacteriocin, class IIa

Bacteriocin_IIa

3

IPR002634

2,634

BolA protein

BolA

Family

29,929

false

This family consist of the morpho-protein BolA from Escherichia coli and its various homologues. In E. coli, over-expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division [ ]. The expression of BolA is growth rate regulate...

[]

0

[ "PFAM", "PIRSF" ]

[ "PF01722", "PIRSF003113" ]

[ "BolA", "BolA" ]

[ 29869, 23313 ]

2

[ "REACTOME" ]

[ "R-HSA-8950505" ]

[ "REACTOME:R-HSA-8950505" ]

1

[ "1ny8", "1v60", "1v9j", "1xs3", "2dhm", "2kdn", "2kz0", "2mcq", "2mm9", "2mma", "2n8q", "2ncl", "3o2e", "3tr3", "4pug", "4puh", "4pui", "5lci", "5nfk", "5nfl", "5nfm", "5y4b", "5zb6" ]

23

[ "PUB00001179", "PUB00003882", "PUB00074298" ]

[ "2684651", "10361282", "22534295" ]

[ "Induction of a growth-phase-dependent promoter triggers transcription of bolA, an Escherichia coli morphogene.", "The stationary-phase morphogene bolA from Escherichia coli is induced by stress during early stages of growth.", "Characterization of the BolA homolog IbaG: a new gene involved in acid resistance."...

[ 1989, 1999, 2012 ]

3

[]

[ "IPR045115" ]

0

1

0

[ "Bacteria", "Eukaryota", "Methanobacteriati", "unclassified sequences" ]

[ 18389, 10905, 330, 305 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 14, 3, 5, 4, 2, 7, 7, 3, 12, 9, 3, 3, 12 ]

13

true

Family

BolA protein

BolA

3

IPR002635

2,635

Chorion protein

Chorion

Family

1,320

false

This family consists of the chorion superfamily proteins classes A, B, CA, CB and high-cysteine HCB from silk, gypsy and polyphemus moths. The chorion proteins make up the moths egg shell - a complex extracellular structure [ ].

[ "GO:0005213", "GO:0007275", "GO:0007304", "GO:0042600" ]

[ "structural constituent of egg chorion", "multicellular organism development", "chorion-containing eggshell formation", "egg chorion" ]

[ "molecular_function", "biological_process", "biological_process", "cellular_component" ]

4

[ "PFAM" ]

[ "PF01723" ]

[ "Chorion_1" ]

[ 1320 ]

1

[]

0

[]

0

[ "PUB00004622" ]

[ "3462711" ]

[ "Evolution of the silk moth chorion gene superfamily: gene families CA and CB." ]

[ 1986 ]

1

[]

0

null

[ "Opisthokonta" ]

[ 1320 ]

1

[]

0

true

Family

Chorion protein

Chorion

6

IPR002636

2,636

Protein from unkown function DUF29

DUF29

Family

7,118

false

This family consists of various bacterial hypothetical proteins, none of which are functionally described. The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.

[]

0

[ "PFAM", "PANTHER" ]

[ "PF01724", "PTHR34235" ]

[ "DUF29", "" ]

[ 7108, 6640 ]

2

[]

0

[ "3fcn" ]

1

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "ecological metagenomes" ]

[ 7099, 6, 5, 8 ]

4

[]

0

true

Family

Protein from unkown function DUF29

DUF29

1

IPR002637

2,637

RdgB/HAM1

Family

33,555

false

This family contains a group of purine NTP pyrophosphatases, including dITP/XTP pyrophosphatase RdgB from E.coli and inosine triphosphate pyrophosphatase (ITPA, also known as HAM1) from Saccharomyces cerevisiae (Baker's yeast) ( ), as well as archaeal and Caenorhabditis elegans homologues. S. cerevisiae HAM1 was origin...

[ "GO:0047429", "GO:0009143" ]

[ "nucleoside triphosphate diphosphatase activity", "nucleoside triphosphate catabolic process" ]

[ "molecular_function", "biological_process" ]

2

[ "PFAM", "PANTHER", "NCBIFAM", "CDD" ]

[ "PF01725", "PTHR11067", "TIGR00042", "cd00515" ]

[ "Ham1p_like", "", "", "HAM1" ]

[ 33532, 32388, 27072, 31349 ]

4

[ "EC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", ...

[ "3.6.1.66", "R-BTA-74259", "R-BTA-9755088", "R-CEL-74259", "R-CEL-9755088", "R-DDI-74259", "R-DDI-9755088", "R-DME-74259", "R-DME-9755088", "R-DRE-74259", "R-DRE-9755088", "R-GGA-74259", "R-GGA-9755088", "R-HSA-74259", "R-HSA-9755088", "R-MMU-74259", "R-MMU-9755088", "R-PFA-74259",...

[ "EC:3.6.1.66", "REACTOME:R-BTA-74259", "REACTOME:R-BTA-9755088", "REACTOME:R-CEL-74259", "REACTOME:R-CEL-9755088", "REACTOME:R-DDI-74259", "REACTOME:R-DDI-9755088", "REACTOME:R-DME-74259", "REACTOME:R-DME-9755088", "REACTOME:R-DRE-74259", "REACTOME:R-DRE-9755088", "REACTOME:R-GGA-74259", "RE...

25

[ "1b78", "1k7k", "1v7r", "1vp2", "2car", "2dvn", "2dvo", "2dvp", "2e5x", "2i5d", "2j4e", "2mjp", "2pyu", "2q16", "2zti", "3s86", "3tqu", "4bnq", "4f95", "6wwd", "8ji1" ]

21

[ "PUB00005658", "PUB00023533", "PUB00046222", "PUB00053239", "PUB00064770", "PUB00064772", "PUB00106860", "PUB00155441" ]

[ "8789257", "10404228", "17976651", "17090528", "17899088", "9918490", "12297000", "38888337" ]

[ "HAM1, the gene controlling 6-N-hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae.", "Structure-based identification of a novel NTPase from Methanococcus jannaschii.", "Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase Rd...

[ 1996, 1999, 2007, 2007, 2007, 1998, 2002, 2024 ]

8

[]

[ "IPR020922", "IPR027502" ]

0

2

0

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 936, 25872, 5740, 299, 708 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 7, 1, 1, 1, 1, 3, 3, 1, 3, 6, 1, 1, 20 ]

13

true

Family

RdgB/HAM1

8

IPR002638

2,638

Quinolinate phosphoribosyl transferase, C-terminal

Quinolinate_PRibosylTrfase_C

Domain

27,190

false

Quinolinate phosphoribosyl transferase (QPRTase) or nicotinate-nucleotide pyrophosphorylase is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg 2+ to give rise to nicotinic acid mo...

[ "GO:0004514", "GO:0009435" ]

[ "nicotinate-nucleotide diphosphorylase (carboxylating) activity", "NAD+ biosynthetic process" ]

[ "molecular_function", "biological_process" ]

2

[ "PFAM" ]

[ "PF01729" ]

[ "QRPTase_C" ]

[ 27190 ]

1

[ "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "2.4.2.19", "PWY-5316", "PWY-5653", "PWY-7342", "PWY-8277", "PWY-8352", "R-DDI-196807", "R-HSA-196807", "R-MMU-196807", "R-RNO-196807", "R-SCE-196807", "R-SSC-196807" ]

[ "EC:2.4.2.19", "METACYC:PWY-5316", "METACYC:PWY-5653", "METACYC:PWY-7342", "METACYC:PWY-8277", "METACYC:PWY-8352", "REACTOME:R-DDI-196807", "REACTOME:R-HSA-196807", "REACTOME:R-MMU-196807", "REACTOME:R-RNO-196807", "REACTOME:R-SCE-196807", "REACTOME:R-SSC-196807" ]

12

[ "1o4u", "1qap", "1qpn", "1qpo", "1qpq", "1qpr", "1x1o", "1ytd", "1yte", "1ytk", "2b7n", "2b7p", "2b7q", "2i14", "2i1o", "2jbm", "3c2e", "3c2f", "3c2o", "3c2r", "3c2v", "3gnn", "3l0g", "3paj", "3tqv", "4i9a", "4kwv", "4kww", "5ayx", "5ayy", "5ayz", "5hul"...

37

[ "PUB00000163", "PUB00005289" ]

[ "8561507", "9016724" ]

[ "The sequencing expression, purification, and steady-state kinetic analysis of quinolinate phosphoribosyl transferase from Escherichia coli.", "A new function for a common fold: the crystal structure of quinolinic acid phosphoribosyltransferase." ]

[ 1996, 1997 ]

2

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 1441, 21596, 3531, 622 ]

4

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Zea mays" ]

[ 7, 1, 4, 1, 2, 1, 11, 1, 5 ]

9

true

Domain

Quinolinate phosphoribosyl transferase, C-terminal

Quinolinate_PRibosylTrfase_C

4

IPR002639

2,639

Urease accessory protein UreF

UreF

Family

13,140

false

This family consists of the urease accessory protein, UreF. The urease enzyme (urea amidohydrolase) hydrolyses urea into ammonia and carbamic acid [ ]. UreF is proposed to modulate the activation process of urease by eliminating the binding of nickel irons to noncarbamylated protein [ ]. This entry also includes the UR...

[ "GO:0016151" ]

[ "nickel cation binding" ]

[ "molecular_function" ]

1

[ "HAMAP", "PFAM", "PIRSF" ]

[ "MF_01385", "PF01730", "PIRSF009467" ]

[ "UreF", "UreF", "Ureas_acces_UreF" ]

[ 10352, 13140, 10822 ]

3

[ "GP" ]

[ "GenProp0051" ]

[ "GP:GenProp0051" ]

1

[ "2wgl", "3cxn", "3o1q", "3sf5", "4hi0", "6jc4", "8hc1" ]

7

[ "PUB00002303", "PUB00002304", "PUB00154981" ]

[ "8808930", "8550495", "23653445" ]

[ "Purification and activation properties of UreD-UreF-urease apoprotein complexes.", "Organization of Ureaplasma urealyticum urease gene cluster and expression in a suppressor strain of Escherichia coli.", "Factors required for activation of urease as a virulence determinant in Cryptococcus neoformans." ]

[ 1996, 1996, 2013 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 184, 10668, 2197, 91 ]

4

[ "Arabidopsis thaliana", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]

[ 3, 1, 3, 1, 3 ]

5

true

Family

Urease accessory protein UreF

UreF

6

IPR002640

2,640

Arylesterase

Family

2,939

false

The serum paraoxonases/arylesterases are enzymes that catalyse the hydrolysis of the toxic metabolites of a variety of organophosphorus insecticides. The enzymes hydrolyse a broad spectrum of organophosphate substrates, including paraoxon and a number of aromatic carboxylic acid esters (e.g., phenyl acetate), and hence...

[ "GO:0004064" ]

[ "arylesterase activity" ]

[ "molecular_function" ]

1

[ "PFAM", "PRINTS" ]

[ "PF01731", "PR01785" ]

[ "Arylesterase", "PARAOXONASE" ]

[ 2861, 1947 ]

2

[ "EC", "EC", "EC", "METACYC", "METACYC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "3.1.1.2", "3.1.1.81", "3.1.8.1", "PWY-5489", "PWY-5490", "PWY-8065", "R-BTA-2142688", "R-CEL-2142688", "R-CEL-9754706", "R-HSA-2142688", "R-HSA-9754706", "R-MMU-2142688", "R-MMU-9754706", "R-RNO-2142688", "R-RNO-9754706" ]

[ "EC:3.1.1.2", "EC:3.1.1.81", "EC:3.1.8.1", "METACYC:PWY-5489", "METACYC:PWY-5490", "METACYC:PWY-8065", "REACTOME:R-BTA-2142688", "REACTOME:R-CEL-2142688", "REACTOME:R-CEL-9754706", "REACTOME:R-HSA-2142688", "REACTOME:R-HSA-9754706", "REACTOME:R-MMU-2142688", "REACTOME:R-MMU-9754706", "REAC...

15

[ "1v04", "3sre", "3srg", "4hho", "4hhq", "4q1u", "6g82", "6gmu", "6h0a", "9r0q" ]

10

[ "PUB00000548", "PUB00001973", "PUB00011231" ]

[ "9032442", "8661009", "11038162" ]

[ "Purification and characterization of paraoxon hydrolase from rat liver.", "The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.", "Human serum paraoxonase (PON1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters." ]

[ 1997, 1996, 2000 ]

3

[]

[ "IPR008363", "IPR008364" ]

0

2

0

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 166, 2759, 14 ]

3

[ "Caenorhabditis elegans", "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 4, 4, 17, 8, 15 ]

5

true

Family

Arylesterase

9

IPR002642

2,642

Lysophospholipase, catalytic domain

LysoPLipase_cat_dom

Domain

13,161

false

This family consists of lysophospholipase / phospholipase B and cytosolic phospholipase A2 which also has a C2 domain . Phospholipase B enzymes catalyse the release of fatty acids from lysophsopholipids and are capable in vitro of hydrolyzing all phospholipids extractable from yeast cells [ ]. Cytosolic phospholipase A...

[ "GO:0004620", "GO:0009395" ]

[ "glycerophospholipase activity", "phospholipid catabolic process" ]

[ "molecular_function", "biological_process" ]

2

[ "PFAM", "PROFILE", "SMART" ]

[ "PF01735", "PS51210", "SM00022" ]

[ "PLA2_B", "PLA2C", "PLAc" ]

[ 12976, 12994, 11645 ]

3

[ "EC", "GP", "METACYC", "PROSITEDOC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REAC...

[ "3.1.1.5", "GenProp1575", "PWY-7409", "PDOC51210", "R-BTA-111995", "R-BTA-1482788", "R-BTA-1482798", "R-BTA-1482801", "R-BTA-1482839", "R-BTA-1482922", "R-BTA-1482925", "R-BTA-1483115", "R-BTA-1483166", "R-BTA-2142753", "R-BTA-418592", "R-BTA-432142", "R-BTA-6811436", "R-DRE-111995...

[ "EC:3.1.1.5", "GP:GenProp1575", "METACYC:PWY-7409", "PROSITEDOC:PDOC51210", "REACTOME:R-BTA-111995", "REACTOME:R-BTA-1482788", "REACTOME:R-BTA-1482798", "REACTOME:R-BTA-1482801", "REACTOME:R-BTA-1482839", "REACTOME:R-BTA-1482922", "REACTOME:R-BTA-1482925", "REACTOME:R-BTA-1483115", "REACTOME...

126

[ "1cjy", "5ixc", "5iz5", "5izr" ]

4

[ "PUB00002859", "PUB00002865" ]

[ "8027085", "8051052" ]

[ "Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.", "The Saccharomyces cerevisiae PLB1 gene encodes a protein required for lysophospholipase and phospholipase B activity." ]

[ 1994, 1994 ]

2

[]

0

null

[ "Bacteria", "Eukaryota", "viral metagenome" ]

[ 12, 13148, 1 ]

3

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 32, 24, 18, 2, 26, 4, 6 ]

7

true

Domain

Lysophospholipase, catalytic domain

LysoPLipase_cat_dom

7

IPR002643

2,643

Polyomavirus agnoprotein

Polyoma_agno

Family

163

false

This family consists of the DNA-binding protein or agnoprotein from various polyomaviruses. This protein is highly basic and can bind single stranded and double stranded DNA [ ]. Mutations in the agnoprotein produce smaller viral plaques, hence its function is not essential for growth in tissue culture cells but someth...

[ "GO:0003677" ]

[ "DNA binding" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF01736" ]

[ "Polyoma_agno" ]

[ 163 ]

1

[]

0

[ "2mj2", "5nhq", "9cmt" ]

3

[ "PUB00003480", "PUB00003976" ]

[ "3027418", "6262654" ]

[ "Role of the agnoprotein in regulation of simian virus 40 replication and maturation pathways.", "Identification of the SV40 agnogene product: a DNA binding protein." ]

[ 1987, 1981 ]

2

[]

0

null

[ "Polyomaviridae" ]

[ 163 ]

1

[]

0

true

Family

Polyomavirus agnoprotein

Polyoma_agno

3

IPR002644

2,644

Photosystem II PsbZ, reaction centre

PSII_PsbZ

Family

15,059

false

Oxygenic photosynthesis uses two multi-subunit photosystems (I and II) located in the cell membranes of cyanobacteria and in the thylakoid membranes of chloroplasts in plants and algae. Photosystem II (PSII) has a P680 reaction centre containing chlorophyll 'a' that uses light energy to carry out the oxidation (splitti...

[ "GO:0015979", "GO:0042549", "GO:0009523", "GO:0009539" ]

[ "photosynthesis", "photosystem II stabilization", "photosystem II", "photosystem II reaction center" ]

[ "biological_process", "biological_process", "cellular_component", "cellular_component" ]

4

[ "HAMAP", "PFAM", "PANTHER", "NCBIFAM" ]

[ "MF_00644", "PF01737", "PTHR34971", "TIGR03043" ]

[ "PSII_PsbZ", "Ycf9", "", "PS_II_psbZ" ]

[ 14727, 15057, 14873, 14999 ]

4

[ "GP" ]

[ "GenProp0661" ]

[ "GP:GenProp0661" ]

1

[ "1s5l", "2axt", "3a0b", "3a0h", "3jcu", "3kzi", "3wu2", "4fby", "4il6", "4ixq", "4ixr", "4pbu", "4pj0", "4rvy", "4tnh", "4tni", "4tnj", "4tnk", "4ub6", "4ub8", "4v62", "4v82", "4yuu", "5b5e", "5b66", "5e79", "5e7c", "5gth", "5gti", "5h2f", "5kaf", "5kai"...

158

[ "PUB00015357", "PUB00015358", "PUB00015359", "PUB00015380", "PUB00097583", "PUB00152828" ]

[ "12518057", "15100025", "14871485", "11402165", "30076221", "33846594" ]

[ "Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.", "The evolutionary development of the protein complement of photosystem 2.", "The low molecular mass subunits of the photosynthetic supracomplex, photosystem II.", "The chloroplast gene ycf9 encodes a ...

[ 2003, 2004, 2004, 2001, 2018, 2021 ]

6

[]

0

null

[ "Bacteria", "Eukaryota", "Methanimicrococcus hacksteinii" ]

[ 360, 14698, 1 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 4, 4, 2 ]

3

true

Family

Photosystem II PsbZ, reaction centre

PSII_PsbZ

1

IPR002645

2,645

STAS domain

STAS_dom

Domain

152,783

false

The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the bacterial anti-sigma factor antagonists (ASA) and the C-terminal region of SLC26 (SulP) anion transporters. The activity of bacterial sigma transcription factors is controlled by a regulatory cascade involving an antisigma-factor, th...

[]

0

[ "PFAM", "PFAM", "PROFILE" ]

[ "PF01740", "PF13466", "PS50801" ]

[ "STAS", "STAS_2", "STAS" ]

[ 118139, 27724, 147689 ]

3

[ "PROSITEDOC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "PDOC50801", "R-BTA-174362", "R-BTA-427601", "R-CEL-174362", "R-CEL-427601", "R-HSA-174362", "R-HSA-3560792", "R-HSA-427601", "R-HSA-5619046", "R-HSA-5619085", "R-HSA-9662361", "R-MMU-174362", "R-MMU-427601", "R-RNO-174362", "R-RNO-427601", "R-SCE-174362", "R-SCE-427601", "R-SPO-17...

[ "PROSITEDOC:PDOC50801", "REACTOME:R-BTA-174362", "REACTOME:R-BTA-427601", "REACTOME:R-CEL-174362", "REACTOME:R-CEL-427601", "REACTOME:R-HSA-174362", "REACTOME:R-HSA-3560792", "REACTOME:R-HSA-427601", "REACTOME:R-HSA-5619046", "REACTOME:R-HSA-5619085", "REACTOME:R-HSA-9662361", "REACTOME:R-MMU-...

20

[ "1auz", "1buz", "1h4x", "1h4y", "1h4z", "1sbo", "1t6r", "1th8", "1thn", "1tid", "1til", "1vc1", "2ka5", "2kln", "2mwg", "2vy9", "3agd", "3age", "3f43", "3if5", "3ih8", "3ih9", "3iha", "3ihb", "3lkl", "3llo", "3mgl", "3ny7", "3oir", "3oiz", "3t6o", "3ztb"...

130

[ "PUB00004920", "PUB00018267", "PUB00018268", "PUB00075356", "PUB00095168", "PUB00161597", "PUB00161598" ]

[ "9560229", "10662676", "10476035", "21070944", "22116355", "1221263", "1221824" ]

[ "Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis.", "The STAS domain - a link between anion transporters and antisigma-factor antagonists.", "Characterization of a morphological checkpoint coupling cell-specific transcript...

[ 1998, 2000, 1999, 2010, 2011, 1975, 1975 ]

7

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Sym plasmid", "Viruses", "unclassified sequences" ]

[ 389, 117806, 33612, 1, 2, 973 ]

6

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 68, 11, 25, 11, 3, 29, 22, 4, 42, 37, 4, 4, 49 ]

13

true

Domain

STAS domain

STAS_dom

2

IPR002646

2,646

Poly A polymerase, head domain

PolA_pol_head_dom

Domain

43,175

false

This group includes nucleic acid independent RNA polymerases, such as polynucleotide adenylyltransferase ( ), which adds the poly (A) tail to mRNA. This group also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA ( ). CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A...

[ "GO:0003723", "GO:0016779", "GO:0006396" ]

[ "RNA binding", "nucleotidyltransferase activity", "RNA processing" ]

[ "molecular_function", "molecular_function", "biological_process" ]

3

[ "PFAM", "CDD" ]

[ "PF01743", "cd05398" ]

[ "PolyA_pol", "NT_ClassII-CCAase" ]

[ 43175, 39921 ]

2

[ "EC", "EC", "REACTOME", "REACTOME" ]

[ "2.7.7", "2.7.7.72", "R-HSA-6784531", "R-HSA-6785470" ]

[ "EC:2.7.7", "EC:2.7.7.72", "REACTOME:R-HSA-6784531", "REACTOME:R-HSA-6785470" ]

4

[ "1miv", "1miw", "1miy", "1ou5", "1vfg", "3aqk", "3aql", "3aqm", "3aqn", "3h37", "3h38", "3h39", "3h3a", "3wfo", "3wfp", "3wfq", "3wfr", "3wfs", "4wby", "4wbz", "4wc0", "4wc1", "4wc2", "4wc3", "4wc4", "4wc5", "4wc6", "4wc7", "4x0a", "4x0b", "4x4w", "5hc9"...

42

[ "PUB00005745", "PUB00013566", "PUB00015829", "PUB00022380", "PUB00058171", "PUB00081108", "PUB00081109", "PUB00081110", "PUB00081111", "PUB00081112", "PUB00081117", "PUB00081118", "PUB00081119", "PUB00081120" ]

[ "7482698", "10075991", "12526808", "12729736", "10361280", "16171400", "16364630", "15737627", "10594833", "10666455", "2204621", "1448105", "1634528", "11504732" ]

[ "DNA polymerase beta belongs to an ancient nucleotidyltransferase superfamily.", "DNA polymerase beta-like nucleotidyltransferase superfamily: identification of three new families, classification and evolutionary history.", "Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complex...

[ 1995, 1999, 2002, 2003, 1999, 2005, 2006, 2005, 1999, 2000, 1990, 1992, 1992, 2001 ]

14

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 24, 35196, 6990, 137, 828 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 37, 1, 3, 2, 2, 9, 2, 1, 10, 4, 1, 2, 18 ]

13

true

Domain

Poly A polymerase, head domain

PolA_pol_head_dom

4

IPR002648

2,648

Adenylate dimethylallyltransferase

Tzs

Family

134

false

Adenylate dimethylallyltransferase transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin phytohormones [ ].

[ "GO:0009824", "GO:0009691" ]

[ "AMP dimethylallyltransferase activity", "cytokinin biosynthetic process" ]

[ "molecular_function", "biological_process" ]

2

[ "PIRSF" ]

[ "PIRSF000507" ]

[ "IPT" ]

[ 134 ]

1

[ "EC", "METACYC" ]

[ "2.5.1.27", "PWY-2681" ]

[ "EC:2.5.1.27", "METACYC:PWY-2681" ]

2

[ "2ze5", "2ze6", "2ze7", "2ze8" ]

4

[ "PUB00089917" ]

[ "16593495" ]

[ "Identification of a cloned cytokinin biosynthetic gene." ]

[ 1984 ]

1

[]

0

null

[ "Bacteria", "Dictyostelium discoideum", "Plasmid Ti" ]

[ 132, 1, 1 ]

3

[]

0

true

Family

Adenylate dimethylallyltransferase

Tzs

1

IPR002649

2,649

tRNA (guanine-N1-)-methyltransferase TrmD

tRNA_m1G_MeTrfase_TrmD

Family

26,130

false

In transfer RNA many different modified nucleosides are found, especially in the anticodon region. tRNA (guanine (N1))-methyltransferase TrmD is one of several nucleases operating together with the tRNA-modifying enzymes before the formation of the mature tRNA. It catalyses the reaction: S-adenosyl-L-methionine + guani...

[ "GO:0052906", "GO:0008033" ]

[ "tRNA (guanine(37)-N1)-methyltransferase activity", "tRNA processing" ]

[ "molecular_function", "biological_process" ]

2

[ "HAMAP", "PIRSF", "PANTHER", "NCBIFAM", "CDD" ]

[ "MF_00605", "PIRSF000386", "PTHR46417", "TIGR00088", "cd18080" ]

[ "TrmD", "tRNA_mtase", "", "trmD", "TrmD-like" ]

[ 25569, 24212, 26126, 24940, 24874 ]

5

[ "EC", "METACYC", "METACYC", "METACYC" ]

[ "2.1.1.228", "PWY-6829", "PWY-7285", "PWY-7286" ]

[ "EC:2.1.1.228", "METACYC:PWY-6829", "METACYC:PWY-7285", "METACYC:PWY-7286" ]

4

[ "1oy5", "1p9p", "1uaj", "1uak", "1ual", "1uam", "3axz", "3ief", "3knu", "3ky7", "3quv", "4h3y", "4h3z", "4ig6", "4mcb", "4mcc", "4mcd", "4ypw", "4ypx", "4ypy", "4ypz", "4yq0", "4yq1", "4yq2", "4yq3", "4yq4", "4yq5", "4yq6", "4yq7", "4yq8", "4yq9", "4yqa"...

140

[ "PUB00006251" ]

[ "2207153" ]

[ "Role of tRNA modification in translational fidelity." ]

[ 1990 ]

1

[]

0

null

[ "Bacteria", "Caudoviricetes", "Eukaryota", "candidate division MSBL1 archaeon SCGC-AAA382N08", "unclassified sequences" ]

[ 25419, 2, 90, 1, 618 ]

5

[ "Escherichia coli (strain K12)", "Homo sapiens" ]

[ 1, 1 ]

2

true

Family

tRNA (guanine-N1-)-methyltransferase TrmD

tRNA_m1G_MeTrfase_TrmD

2

IPR002653

2,653

Zinc finger, A20-type

Znf_A20

Domain

15,710

false

Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not; instead binding other metals such as iron, or no metal at all. For example, some family members form salt b...

[ "GO:0003677", "GO:0008270" ]

[ "DNA binding", "zinc ion binding" ]

[ "molecular_function", "molecular_function" ]

2

[ "PFAM", "PROFILE", "SMART" ]

[ "PF01754", "PS51036", "SM00259" ]

[ "zf-A20", "ZF_A20", "ZnF_A20" ]

[ 15400, 15513, 14739 ]

3

[ "PROSITEDOC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "PDOC51036", "R-BTA-9033241", "R-HSA-168638", "R-HSA-5357786", "R-HSA-5357905", "R-HSA-5357956", "R-HSA-5689896", "R-HSA-8854214", "R-HSA-8876198", "R-HSA-9033241", "R-HSA-936440", "R-MMU-168638", "R-MMU-5357786", "R-MMU-5357905", "R-MMU-5357956", "R-MMU-5689896", "R-MMU-8876198", ...

[ "PROSITEDOC:PDOC51036", "REACTOME:R-BTA-9033241", "REACTOME:R-HSA-168638", "REACTOME:R-HSA-5357786", "REACTOME:R-HSA-5357905", "REACTOME:R-HSA-5357956", "REACTOME:R-HSA-5689896", "REACTOME:R-HSA-8854214", "REACTOME:R-HSA-8876198", "REACTOME:R-HSA-9033241", "REACTOME:R-HSA-936440", "REACTOME:R-...

20

[ "2c7m", "2c7n", "2eqe", "2eqf", "2eqg", "2fid", "2fif", "2kzy", "2l00", "3oj3", "3oj4", "3vuw", "3vux", "3vuy", "7qxw", "9bui" ]

16

[ "PUB00014077", "PUB00035804", "PUB00035805", "PUB00035806", "PUB00035807", "PUB00035812", "PUB00035822" ]

[ "12665246", "17210253", "15963892", "15718139", "10529348", "11179890", "17449604" ]

[ "Zinc fingers--folds for many occasions.", "Sticky fingers: zinc-fingers as protein-recognition motifs.", "Multiple modes of RNA recognition by zinc finger proteins.", "Zinc finger proteins: getting a grip on RNA.", "Zinc finger peptides for the regulation of gene expression.", "Zinc finger proteins: new ...

[ 2002, 2007, 2005, 2005, 1999, 2001, 2007 ]

7

[]

0

null

[ "Cellulomonas uda", "Eukaryota", "Gaeavirus sp.", "ecological metagenomes" ]

[ 1, 15706, 1, 2 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]

[ 30, 3, 37, 3, 34, 20, 21, 22, 22 ]

9

true

Domain

Zinc finger, A20-type

Znf_A20

7

IPR002654

2,654

Glycosyl transferase, family 25

Glyco_trans_25

Domain

14,161

false

The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferas...

[]

0

[ "PFAM", "CDD" ]

[ "PF01755", "cd06532" ]

[ "Glyco_transf_25", "Glyco_transf_25" ]

[ 13494, 12178 ]

2

[ "CAZY", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "GT25", "R-BTA-1650814", "R-DME-1650814", "R-DRE-1650814", "R-HSA-1650814", "R-MMU-1650814" ]

[ "CAZY:GT25", "REACTOME:R-BTA-1650814", "REACTOME:R-DME-1650814", "REACTOME:R-DRE-1650814", "REACTOME:R-HSA-1650814", "REACTOME:R-MMU-1650814" ]

6

[ "8xc8", "8xgx", "8xkd", "8xlz", "8xoc", "8zgc", "8zge", "8zgg", "8zgh", "9crz", "9evj", "9evk", "9evl" ]

13

[ "PUB00003874", "PUB00009409" ]

[ "8817494", "9334165" ]

[ "Molecular analysis of a locus for the biosynthesis and phase-variable expression of the lacto-N-neotetraose terminal lipopolysaccharide structure in Neisseria meningitidis.", "A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities." ]

[ 1995, 1997 ]

2

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 3, 5841, 7454, 355, 508 ]

5

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus" ]

[ 1, 7, 1, 15, 5, 2, 9 ]

7

true

Domain

Glycosyl transferase, family 25

Glyco_trans_25

4

IPR002655

2,655

Acyl-CoA oxidase, C-terminal

Acyl-CoA_oxidase_C

Domain

17,237

false

Acyl-CoA oxidase (ACO) acts on CoA derivatives of fatty acids with chain lengths from 8 to 18. It catalyses the first and rate-determining step of the peroxisomal beta-oxidation of fatty acids [ ]. Acyl-CoA oxidase is a homodimer and the polypeptide chain of the subunit is folded into the N-terminal alpha-domain, beta-...

[ "GO:0003997", "GO:0006635", "GO:0005777" ]

[ "acyl-CoA oxidase activity", "fatty acid beta-oxidation", "peroxisome" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM" ]

[ "PF01756" ]

[ "ACOX" ]

[ 17237 ]

1

[ "EC", "GP", "GP", "GP", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REAC...

[ "1.3.3.6", "GenProp1308", "GenProp1510", "GenProp1544", "PWY-5136", "PWY-6837", "PWY-6920", "PWY-7007", "PWY-7288", "PWY-7291", "PWY-7337", "PWY-7338", "PWY-7340", "PWY-735", "PWY-7574", "PWY-7606", "PWY-7726", "PWY-7854", "PWY-7858", "R-BTA-2046106", "R-BTA-390247", "R-BTA...

[ "EC:1.3.3.6", "GP:GenProp1308", "GP:GenProp1510", "GP:GenProp1544", "METACYC:PWY-5136", "METACYC:PWY-6837", "METACYC:PWY-6920", "METACYC:PWY-7007", "METACYC:PWY-7288", "METACYC:PWY-7291", "METACYC:PWY-7337", "METACYC:PWY-7338", "METACYC:PWY-7340", "METACYC:PWY-735", "METACYC:PWY-7574", ...

56

[ "1is2", "1w07", "2ddh", "2fon", "5k3g", "5k3h", "5k3i", "5k3j", "5y9d", "5ys9", "7q84", "7q86" ]

12

[ "PUB00003040", "PUB00026133", "PUB00032141" ]

[ "9525937", "11872165", "15581893" ]

[ "Molecular characterization of a glyoxysomal long chain acyl-CoA oxidase that is synthesized as a precursor of higher molecular mass in pumpkin.", "Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase.", "Acyl-CoA ...

[ 1998, 2002, 2005 ]

3

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 3446, 13773, 18 ]

3

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Zea mays" ]

[ 30, 7, 9, 11, 15, 11, 9, 28, 1, 28 ]

10

true

Domain

Acyl-CoA oxidase, C-terminal

Acyl-CoA_oxidase_C

7

IPR002656

2,656

Acyltransferase 3 domain

Acyl_transf_3_dom

Domain

110,124

false

This entry represents the acyltransferase domain present in a wide range of acyltransferase enzymes, including, mainly, bacterial proteins which catalyse the transfer of acyl groups, other than amino-acyl, from one compound to another, such as Glucans biosynthesis protein C (OPGC) or protein OatA from Listeria monocyto...

[ "GO:0016747" ]

[ "acyltransferase activity, transferring groups other than amino-acyl groups" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF01757" ]

[ "Acyl_transf_3" ]

[ 110124 ]

1

[]

0

[]

0

[ "PUB00043794", "PUB00043795", "PUB00043796", "PUB00043797", "PUB00097283", "PUB00097284", "PUB00097285", "PUB00097286" ]

[ "16861647", "17676995", "15661003", "10755312", "32350117", "21844299", "16980385", "16118202" ]

[ "The presence of peptidoglycan O-acetyltransferase in various staphylococcal species correlates with lysozyme resistance and pathogenicity.", "Molecular basis of resistance to muramidase and cationic antimicrobial peptide activity of lysozyme in staphylococci.", "Why are pathogenic staphylococci so lysozyme res...

[ 2006, 2007, 2005, 2000, 2020, 2011, 2006, 2006 ]

8

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Megaplasmid pSym", "Viruses", "unclassified sequences" ]

[ 401, 91746, 16940, 1, 44, 992 ]

6

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus" ]

[ 1, 70, 8, 40, 3, 1, 4, 3 ]

8

true

Domain

Acyltransferase 3 domain

Acyl_transf_3_dom

6

IPR002657

2,657

Bile acid:sodium symporter/arsenical resistance protein Acr3

BilAc:Na_symport/Acr3

Family

41,948

false

This family of proteins are found both in prokaryotes and eukaryotes. They are related to the human bile acid:sodium symporters (TC 2.A.28), which are transmembrane proteins functioning in the liver in the uptake of bile acids from portal blood plasma, a process mediated by the co-transport of Na + [ ]. This entry also...

[ "GO:0016020" ]

[ "membrane" ]

[ "cellular_component" ]

1

[ "PFAM" ]

[ "PF01758" ]

[ "SBF" ]

[ 41948 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-159418", "R-HSA-425366", "R-MMU-159418", "R-MMU-425366", "R-RNO-159418", "R-RNO-425366" ]

[ "REACTOME:R-HSA-159418", "REACTOME:R-HSA-425366", "REACTOME:R-MMU-159418", "REACTOME:R-MMU-425366", "REACTOME:R-RNO-159418", "REACTOME:R-RNO-425366" ]

6

[ "3zux", "3zuy", "4n7w", "4n7x", "6lgv", "6lgy", "6lgz", "6lh0", "6lh1", "7cyg", "7cyk", "7fci", "7pqg", "7pqq", "7vad", "7vae", "7vaf", "7vag", "7wsi", "7zyi", "8hrx", "8hry", "8oyf", "8oyg", "8rqf", "8xcd", "9qzq" ]

27

[ "PUB00004723", "PUB00005662", "PUB00070752", "PUB00070753", "PUB00070754", "PUB00070755", "PUB00070756", "PUB00070758", "PUB00070759", "PUB00072662" ]

[ "1961729", "9234670", "19494117", "22102279", "18088595", "20530755", "24291645", "19039703", "12949088", "21447319" ]

[ "Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.", "Isolation of three contiguous genes, ACR1, ACR2 and ACR3, involved in resistance to arsenic compounds in the yeast Saccharomyces cerevisiae.", "Properties of arsenite efflux permeases (Acr3) from Alkaliphi...

[ 1991, 1997, 2009, 2012, 2008, 2010, 2014, 2008, 2003, 2011 ]

10

[]

[ "IPR004706", "IPR004710" ]

0

2

0

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 1049, 28811, 11543, 545 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 18, 1, 7, 3, 9, 15, 1, 10, 16, 1, 20 ]

11

true

Family

Bile acid:sodium symporter/arsenical resistance protein Acr3

BilAc:Na_symport/Acr3

7

IPR002659

2,659

Glycosyl transferase, family 31

Glyco_trans_31

Family

41,147

false

The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferas...

[ "GO:0016758", "GO:0009101", "GO:0016020" ]

[ "hexosyltransferase activity", "glycoprotein biosynthetic process", "membrane" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM", "PANTHER" ]

[ "PF01762", "PTHR11214" ]

[ "Galactosyl_T", "" ]

[ 39718, 39564 ]

2

[ "CAZY", "EC", "GP", "GP", "GP", "GP", "GP", "GP", "GP", "GP", "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "R...

[ "GH31", "2.4.1", "GenProp1304", "GenProp1444", "GenProp1455", "GenProp1517", "GenProp1518", "GenProp1539", "GenProp1545", "GenProp1699", "GenProp1712", "R-BTA-913709", "R-CEL-1971475", "R-CFA-9037629", "R-CFA-9840309", "R-DRE-8932505", "R-DRE-913709", "R-DRE-9840309", "R-HSA-1971...

[ "CAZY:GH31", "EC:2.4.1", "GP:GenProp1304", "GP:GenProp1444", "GP:GenProp1455", "GP:GenProp1517", "GP:GenProp1518", "GP:GenProp1539", "GP:GenProp1545", "GP:GenProp1699", "GP:GenProp1712", "REACTOME:R-BTA-913709", "REACTOME:R-CEL-1971475", "REACTOME:R-CFA-9037629", "REACTOME:R-CFA-9840309"...

40

[ "6wmm", "6wmn", "6wmo", "7jhi", "7jhk", "7jhl", "7jhm", "7jhn", "7jho", "8sz3", "8tic", "8tjc", "8zwp", "8zwr", "8zww", "8zwy", "8zx2", "8zx3", "8zx8", "8zx9" ]

20

[ "PUB00003033", "PUB00003036", "PUB00009409" ]

[ "9417100", "9417047", "9334165" ]

[ "Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase catalyzing the formation of type 1 chains.", "Genomic cloning and expression of three murine UDP-galactose: beta-N-acetylglucosamine beta1,3-galactosyltransferase genes.", "A classification of nucleotide-diphospho-sugar ...

[ 1998, 1998, 1997 ]

3

[]

0

null

[ "Eukaryota", "Pseudomonadati", "Viruses", "metagenomes" ]

[ 41011, 84, 6, 46 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]

[ 114, 22, 75, 20, 43, 26, 96, 37, 1, 172 ]

10

true

Family

Glycosyl transferase, family 31

Glyco_trans_31

3

IPR002660

2,660

Herpesvirus portal protein

Herpes_Portal

Family

689

false

This family consists of various proteins from the Herpesviridae that are similar to Human herpesvirus 1 (HHV-1) UL6 virion protein. UL6 is essential for cleavage and packaging of the viral genome [ ]. UL6 forms the DNA entry portal; it exists at a unique site in the capsid and forms a channel for entry of DNA into the ...

[ "GO:0051276" ]

[ "chromosome organization" ]

[ "biological_process" ]

1

[ "HAMAP", "PFAM" ]

[ "MF_04012", "PF01763" ]

[ "HSV_PORTL", "Herpes_UL6" ]

[ 518, 689 ]

2

[ "REACTOME", "REACTOME" ]

[ "R-HSA-9609690", "R-HSA-9610379" ]

[ "REACTOME:R-HSA-9609690", "REACTOME:R-HSA-9610379" ]

2

[ "6od7", "6ppi", "6rvr", "6rvs", "7bqt", "7et2", "7etm", "8heu", "8hev", "9op4", "9op5", "9op8", "9opb", "9opc", "9opv" ]

15

[ "PUB00005618", "PUB00079185" ]

[ "8955060", "11602732" ]

[ "The herpes simplex virus type 1 UL6 protein is essential for cleavage and packaging but not for genomic inversion.", "The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid." ]

[ 1996, 2001 ]

2

[]

0

null

[ "Desertifilum tharense IPPAS B-1220", "Herpesvirales", "Homo sapiens" ]

[ 1, 687, 1 ]

3

[ "Homo sapiens" ]

[ 1 ]

1

true

Family

Herpesvirus portal protein

Herpes_Portal

5

IPR002661

2,661

Ribosome recycling factor

Ribosome_recyc_fac

Family

30,214

false

The ribosome recycling factor or ribosome release factor (RRF) dissociates ribosomes from mRNA after termination of translation, and is essential for bacterial growth [ ]. Thus ribosomes are 'recycled' and ready for another round of protein synthesis. RRF is believed to bind the ribosome at the A-site in a manner that ...

[ "GO:0006412" ]

[ "translation" ]

[ "biological_process" ]

1

[ "HAMAP", "PANTHER", "NCBIFAM", "CDD" ]

[ "MF_00040", "PTHR20982", "TIGR00496", "cd00520" ]

[ "RRF", "", "frr", "RRF" ]

[ 24503, 30191, 25117, 24524 ]

4

[ "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "GenProp0746", "R-CEL-5419276", "R-HSA-5419276", "R-MMU-5419276", "R-RNO-5419276" ]

[ "GP:GenProp0746", "REACTOME:R-CEL-5419276", "REACTOME:R-HSA-5419276", "REACTOME:R-MMU-5419276", "REACTOME:R-RNO-5419276" ]

5

[ "1dd5", "1eh1", "1ek8", "1ge9", "1is1", "1ise", "1t1m", "1wih", "1wqf", "1wqg", "1wqh", "1y69", "1zn0", "1zn1", "2rdo", "3j0d", "3j0e", "3lf9", "4gfq", "4kaw", "4kb2", "4kb4", "4kc6", "4kdd", "4v54", "4v55", "4v5a", "4v5y", "4v9c", "4v9d", "4woi", "5mlc"...

42

[ "PUB00004841", "PUB00080488" ]

[ "8183897", "11214182" ]

[ "Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth.", "Functional mapping of ribosome-contact sites in the ribosome recycling factor: a structural view from a tRNA mimic." ]

[ 1994, 2001 ]

2

[]

0

null

[ "Bacteria", "Eukaryota", "Myoviridae sp. ctj4n23", "Thermococcus litoralis", "unclassified sequences" ]

[ 24301, 5341, 1, 1, 570 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 8, 1, 2, 2, 1, 2, 1, 1, 4, 4, 1, 1, 17 ]

13

true

Family

Ribosome recycling factor

Ribosome_recyc_fac

7

IPR002662

2,662

Birnavirus VP2 protein

Birna_VP2

Family

4,968

false

Infectious pancreatic necrosis virus (IPNV), a birnavirus, is an important pathogen in fish farms. Analyses of viral proteins showed that VP2 is the major structural and immunogenic polypeptide of the virus [ , ]. All neutralizing monoclonal antibodies are specific to VP2 and bind to continuous or discontinuous epitope...

[ "GO:0005198" ]

[ "structural molecule activity" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF01766" ]

[ "Birna_VP2" ]

[ 4968 ]

1

[ "EC", "METACYC" ]

[ "3.4.21.-", "PWY-7884" ]

[ "EC:3.4.21.-", "METACYC:PWY-7884" ]

2

[ "1wcd", "1wce", "2df7", "2gsy", "3fbm", "3ide", "7vrn", "7vrp", "9gg2" ]

9

[ "PUB00003481", "PUB00005611", "PUB00043618", "PUB00043619" ]

[ "2828658", "8525637", "17976679", "15669113" ]

[ "Birnavirus precursor polyprotein is processed in Escherichia coli by its own virus-encoded polypeptide.", "Strain variability and localization of important epitopes on the major structural protein (VP2) of infectious pancreatic necrosis virus.", "Genome and polypeptides characterization of Tellina virus 1 reve...

[ 1988, 1995, 2008, 2004 ]

4

[]

0

null

[ "Pelinobius muticus", "Viruses" ]

[ 1, 4967 ]

2

[]

0

true

Family

Birnavirus VP2 protein

Birna_VP2

9

IPR002663

2,663

Birnavirus VP3 protein

Birna_VP3

Family

460

false

Birnavirus VP3 is involved in virus morphogenesis. It interacts with the structural protein VP2, with the double-stranded RNA genome, and with the virus-encoded, RNA-dependent RNA polymerase (RdRP), VP1, playing a role in both viral capsid formation, recruitment of VP1 into the capsid and encapsidation of the viral gen...

[ "GO:0005198" ]

[ "structural molecule activity" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF01767" ]

[ "Birna_VP3" ]

[ 460 ]

1

[ "EC", "METACYC" ]

[ "3.4.21.-", "PWY-7884" ]

[ "EC:3.4.21.-", "METACYC:PWY-7884" ]

2

[ "2r18", "2z7j", "3zed", "6shw", "6si6", "9eqn", "9eqo", "9eqp" ]

8

[ "PUB00049219" ]

[ "18184581" ]

[ "Structural insights into the multifunctional protein VP3 of birnaviruses." ]

[ 2008 ]

1

[]

0

null

[ "Salmonella diarizonae", "Viruses" ]

[ 1, 459 ]

2

[]

0

true

Family

Birnavirus VP3 protein

Birna_VP3

9

IPR002666

2,666

Reduced folate carrier

Folate_carrier

Family

5,695

false

This entry represents the reduced folate carrier family, including folate transporter 1 (SLC19A1), thiamine transporter 1 (SLC19A2) and thiamine transporter 2 (SLC19A3). Despite their protein sequence/structure similarity, they have different functions. The transporter 1 (SLC19A1, also known as the reduced folate carri...

[ "GO:0090482", "GO:0051180", "GO:0016020" ]

[ "vitamin transmembrane transporter activity", "vitamin transport", "membrane" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM", "PIRSF", "PANTHER", "NCBIFAM" ]

[ "PF01770", "PIRSF028739", "PTHR10686", "TIGR00806" ]

[ "Folate_carrier", "Folate_carrier", "", "rfc" ]

[ 5680, 3340, 5585, 3578 ]

4

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-CEL-196757", "R-CEL-196819", "R-DDI-196757", "R-DDI-196819", "R-HSA-196757", "R-HSA-196819", "R-MMU-196757", "R-MMU-196819", "R-RNO-196757" ]

[ "REACTOME:R-CEL-196757", "REACTOME:R-CEL-196819", "REACTOME:R-DDI-196757", "REACTOME:R-DDI-196819", "REACTOME:R-HSA-196757", "REACTOME:R-HSA-196819", "REACTOME:R-MMU-196757", "REACTOME:R-MMU-196819", "REACTOME:R-RNO-196757" ]

9

[ "7tx6", "7tx7", "7xpz", "7xq0", "7xq1", "7xq2", "7xtk", "8dep", "8goe", "8gof", "8hii", "8hij", "8hik", "8s4u", "8s5u", "8s5w", "8s5z", "8s61", "8s62", "8xv2", "8xv5", "8xv9", "8z7r", "8z7s", "8z7t", "8z7u", "8z7v", "8z7w", "8z7x", "8z7y", "8z7z", "8z80"...

40

[ "PUB00001873", "PUB00068067", "PUB00095223" ]

[ "9161403", "11731220", "31511694" ]

[ "Organization, structure and alternate splicing of the murine RFC-1 gene encoding a folate transporter.", "SLC19A3 encodes a second thiamine transporter ThTr2.", "SLC19A1 transports immunoreactive cyclic dinucleotides." ]

[ 1997, 2001, 2019 ]

3

[]

[ "IPR028337", "IPR028338", "IPR028339" ]

0

3

0

[ "Eukaryota" ]

[ 5695 ]

1

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 3, 20, 4, 28, 14, 14 ]

6

true

Family

Reduced folate carrier

Folate_carrier

3

IPR002669

2,669

Urease accessory protein UreD

UreD

Family

13,469

false

UreD is a urease accessory protein. Urease hydrolyses urea into ammonia and carbamic acid [ ]. UreD is involved in activation of the urease enzyme via the UreD-UreF-UreG-urease complex [ ] and is required for urease nickel metallocentre assembly [ ]. This entry includes UreH from Helicobacter pylori, which is an orthol...

[ "GO:0016151" ]

[ "nickel cation binding" ]

[ "molecular_function" ]

1

[ "HAMAP", "PFAM", "PANTHER" ]

[ "MF_01384", "PF01774", "PTHR33643" ]

[ "UreD", "UreD", "" ]

[ 12077, 13432, 10981 ]

3

[ "GP" ]

[ "GenProp0051" ]

[ "GP:GenProp0051" ]

1

[ "3sf5", "4hi0", "8hc1", "8hcn" ]

4

[ "PUB00002304", "PUB00002310", "PUB00004836", "PUB00070746", "PUB00154981" ]

[ "8550495", "9209019", "7909161", "24115911", "23653445" ]

[ "Organization of Ureaplasma urealyticum urease gene cluster and expression in a suppressor strain of Escherichia coli.", "Characterization of UreG, identification of a UreD-UreF-UreG complex, and evidence suggesting that a nucleotide-binding site in UreG is required for in vivo metallocenter assembly of Klebsiell...

[ 1996, 1997, 1994, 2013, 2013 ]

5

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 183, 10755, 2440, 91 ]

4

[ "Arabidopsis thaliana", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]

[ 6, 1, 3, 1, 4 ]

5

true

Family

Urease accessory protein UreD

UreD

2

IPR002671

2,671

Large ribosomal subunit protein eL22

Ribosomal_eL22

Family

7,502

false

This entry represents the large ribosomal subunit protein eL22 family. Ribosomal protein eL22 forms part of the 60S ribosomal subunit [ ] found in eukaryotes. Rattus norvegicus (Rat) eL22 is related to ribosomal proteins from other eukaryotes and is identical in amino acid sequence to human EAP, the EBER 1 (Epstein-Bar...

[ "GO:0003735", "GO:0006412", "GO:0005840" ]

[ "structural constituent of ribosome", "translation", "ribosome" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM", "PANTHER" ]

[ "PF01776", "PTHR10064" ]

[ "Ribosomal_L22e", "" ]

[ 7492, 7380 ]

2

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-CEL-156827", "R-CEL-1799339", "R-CEL-72689", "R-CEL-72706", "R-CEL-975956", "R-CEL-975957", "R-DME-156827", "R-DME-1799339", "R-DME-72689", "R-DME-72706", "R-DME-975956", "R-DME-975957", "R-GGA-1799339", "R-GGA-72689", "R-GGA-72706", "R-GGA-975956", "R-GGA-975957", "R-HSA-156827...

[ "REACTOME:R-CEL-156827", "REACTOME:R-CEL-1799339", "REACTOME:R-CEL-72689", "REACTOME:R-CEL-72706", "REACTOME:R-CEL-975956", "REACTOME:R-CEL-975957", "REACTOME:R-DME-156827", "REACTOME:R-DME-1799339", "REACTOME:R-DME-72689", "REACTOME:R-DME-72706", "REACTOME:R-DME-975956", "REACTOME:R-DME-97595...

58

[ "3j6x", "3j6y", "3j77", "3j78", "3j79", "3j7o", "3j7p", "3j7q", "3j7r", "3j92", "3jag", "3jah", "3jai", "3jaj", "3jan", "3jbn", "3jbo", "3jbp", "3jcs", "3jct", "4d5y", "4d67", "4u3m", "4u3n", "4u3u", "4u4n", "4u4o", "4u4q", "4u4r", "4u4u", "4u4y", "4u4z"...

548

[ "PUB00000194", "PUB00006313", "PUB00007068", "PUB00007069", "PUB00007070" ]

[ "1840484", "7999786", "11297922", "11290319", "11114498" ]

[ "The primary structure of rat ribosomal protein L38.", "The primary structure of rat ribosomal protein L22.", "Atomic structures at last: the ribosome in 2000.", "The ribosome in focus.", "The end of the beginning: structural studies of ribosomal proteins." ]

[ 1991, 1995, 2001, 2001, 2000 ]

5

[]

0

null

[ "Bacteria", "Eukaryota", "Odinarchaeota yellowstonii (strain LCB_4)", "unclassified sequences" ]

[ 2, 7492, 1, 7 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 10, 1, 4, 4, 12, 4, 1, 5, 15, 2, 1, 13 ]

12

true

Family

Large ribosomal subunit protein eL22

Ribosomal_eL22

8

IPR002672

2,672

Large ribosomal subunit protein eL28

Ribosomal_eL28

Family

5,770

false

This entry represents the large ribosomal subunit protein eL28 family. Ribosomal protein eL28 forms part of the 60S ribosomal subunit [ ]. This entry is found in eukaryotes. In rat there are 9 or 10 copies of the eL28 gene. The eL28 protein contains a possible internal duplication of 9 residues [ ]. Ribosomes are the p...

[ "GO:0003735", "GO:0006412", "GO:0005840" ]

[ "structural constituent of ribosome", "translation", "ribosome" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PANTHER" ]

[ "PTHR10544" ]

[ "" ]

[ 5770 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-CEL-156827", "R-CEL-1799339", "R-CEL-72689", "R-CEL-72706", "R-CEL-975956", "R-CEL-975957", "R-DDI-156827", "R-DDI-1799339", "R-DDI-72689", "R-DDI-72706", "R-DDI-975956", "R-DDI-975957", "R-DME-156827", "R-DME-1799339", "R-DME-72689", "R-DME-72706", "R-DME-975956", "R-DME-975957...

[ "REACTOME:R-CEL-156827", "REACTOME:R-CEL-1799339", "REACTOME:R-CEL-72689", "REACTOME:R-CEL-72706", "REACTOME:R-CEL-975956", "REACTOME:R-CEL-975957", "REACTOME:R-DDI-156827", "REACTOME:R-DDI-1799339", "REACTOME:R-DDI-72689", "REACTOME:R-DDI-72706", "REACTOME:R-DDI-975956", "REACTOME:R-DDI-97595...

51

[ "3j7o", "3j7p", "3j7q", "3j7r", "3j92", "3jag", "3jah", "3jai", "3jaj", "3jan", "3jcs", "4d5y", "4d67", "4ug0", "4ujc", "4ujd", "4uje", "4v3p", "4v6w", "4v6x", "4v7e", "4v8m", "4v8p", "5aj0", "5lks", "5lzs", "5lzt", "5lzu", "5lzv", "5lzw", "5lzx", "5lzy"...

284

[ "PUB00000194", "PUB00006252", "PUB00007068", "PUB00007069", "PUB00007070" ]

[ "1840484", "2207170", "11297922", "11290319", "11114498" ]

[ "The primary structure of rat ribosomal protein L38.", "The primary structure of rat ribosomal proteins: the amino acid sequences of L27a and L28 and corrections in the sequences of S4 and S12.", "Atomic structures at last: the ribosome in 2000.", "The ribosome in focus.", "The end of the beginning: structu...

[ 1991, 1990, 2001, 2001, 2000 ]

5

[]

0

null

[ "Bacteria", "Eukaryota", "bird metagenome" ]

[ 3, 5766, 1 ]

3

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Schizosaccharomyces pombe (stra...

[ 5, 1, 3, 3, 6, 4, 1, 9, 8, 1, 13 ]

11

true

Family

Large ribosomal subunit protein eL28

Ribosomal_eL28

3

IPR002673

2,673

Large ribosomal subunit protein eL29

Ribosomal_eL29

Family

4,348

false

This entry represents the large ribosomal subunit protein eL29 family. Ribosomal protein eL29 forms part of the 60S ribosomal subunit [ ]. This family is found in eukaryotes. There are there are 20 to 22 copies of the eL29 gene in Rattus norvegicus (Rat). Rat eL29 is related to yeast ribosomal protein YL43 [ ]. Ribosom...

[ "GO:0003735", "GO:0006412", "GO:0005840" ]

[ "structural constituent of ribosome", "translation", "ribosome" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM", "PANTHER" ]

[ "PF01779", "PTHR12884" ]

[ "Ribosomal_L29e", "" ]

[ 4319, 4193 ]

2

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-BTA-156827", "R-BTA-1799339", "R-BTA-6791226", "R-BTA-72689", "R-BTA-72706", "R-BTA-975956", "R-BTA-975957", "R-DDI-156827", "R-DDI-1799339", "R-DDI-72689", "R-DDI-72706", "R-DDI-975956", "R-DDI-975957", "R-DME-156827", "R-DME-1799339", "R-DME-72689", "R-DME-72706", "R-DME-97595...

[ "REACTOME:R-BTA-156827", "REACTOME:R-BTA-1799339", "REACTOME:R-BTA-6791226", "REACTOME:R-BTA-72689", "REACTOME:R-BTA-72706", "REACTOME:R-BTA-975956", "REACTOME:R-BTA-975957", "REACTOME:R-DDI-156827", "REACTOME:R-DDI-1799339", "REACTOME:R-DDI-72689", "REACTOME:R-DDI-72706", "REACTOME:R-DDI-9759...

65

[ "3j6x", "3j6y", "3j77", "3j78", "3j79", "3j7o", "3j7p", "3j7q", "3j7r", "3j92", "3jag", "3jah", "3jai", "3jaj", "3jan", "3jbn", "3jbo", "3jbp", "3jcs", "4d5y", "4d67", "4u3m", "4u3n", "4u3u", "4u4n", "4u4o", "4u4q", "4u4r", "4u4u", "4u4y", "4u4z", "4u50"...

491

[ "PUB00000194", "PUB00006282", "PUB00007068", "PUB00007069", "PUB00007070" ]

[ "1840484", "8484767", "11297922", "11290319", "11114498" ]

[ "The primary structure of rat ribosomal protein L38.", "The primary structure of rat ribosomal protein L29.", "Atomic structures at last: the ribosome in 2000.", "The ribosome in focus.", "The end of the beginning: structural studies of ribosomal proteins." ]

[ 1991, 1993, 2001, 2001, 2000 ]

5

[]

0

null

[ "Eukaryota", "Gammaproteobacteria" ]

[ 4346, 2 ]

2

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 10, 1, 1, 4, 5, 5, 1, 2, 16, 1, 1, 26 ]

12

true

Family

Large ribosomal subunit protein eL29

Ribosomal_eL29

8

IPR002674

2,674

Large ribosomal subunit protein eL43

Ribosomal_eL43

Family

6,798

false

This entry represents the large ribosomal subunit protein eL43 family. This ribosomal protein is found in archaebacteria and eukaryotes [ ]. Ribosomal protein eL43, also known as L37A, has a single zinc finger-like motif of the C2-C2 type [ ]. Ribosomes are the particles that catalyse mRNA-directed protein synthesis in...

[ "GO:0003735", "GO:0006412", "GO:0005840" ]

[ "structural constituent of ribosome", "translation", "ribosome" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "HAMAP", "PFAM", "NCBIFAM" ]

[ "MF_00327", "PF01780", "TIGR00280" ]

[ "Ribosomal_eL43", "Ribosomal_L37ae", "eL43_euk_arch" ]

[ 5254, 6797, 5039 ]

3

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-BTA-156827", "R-BTA-1799339", "R-BTA-6791226", "R-BTA-72689", "R-BTA-72706", "R-BTA-975956", "R-BTA-975957", "R-CEL-156827", "R-CEL-1799339", "R-CEL-72689", "R-CEL-72706", "R-CEL-975956", "R-CEL-975957", "R-HSA-156827", "R-HSA-156902", "R-HSA-1799339", "R-HSA-192823", "R-HSA-240...

[ "REACTOME:R-BTA-156827", "REACTOME:R-BTA-1799339", "REACTOME:R-BTA-6791226", "REACTOME:R-BTA-72689", "REACTOME:R-BTA-72706", "REACTOME:R-BTA-975956", "REACTOME:R-BTA-975957", "REACTOME:R-CEL-156827", "REACTOME:R-CEL-1799339", "REACTOME:R-CEL-72689", "REACTOME:R-CEL-72706", "REACTOME:R-CEL-9759...

33

[ "1ffk", "1jj2", "1k73", "1k8a", "1k9m", "1kc8", "1kd1", "1kqs", "1m1k", "1m90", "1n8r", "1nji", "1q7y", "1q81", "1q82", "1q86", "1qvf", "1qvg", "1s72", "1vq4", "1vq5", "1vq6", "1vq7", "1vq8", "1vq9", "1vqk", "1vql", "1vqm", "1vqn", "1vqo", "1vqp", "1w2b"...

626

[ "PUB00000223", "PUB00006242", "PUB00007068", "PUB00007069", "PUB00007070" ]

[ "8484768", "2546769", "11297922", "11290319", "11114498" ]

[ "The primary structure of L37--a rat ribosomal protein with a zinc finger-like motif.", "The primary structure of rat ribosomal protein L37a.", "Atomic structures at last: the ribosome in 2000.", "The ribosome in focus.", "The end of the beginning: structural studies of ribosomal proteins." ]

[ 1993, 1989, 2001, 2001, 2000 ]

5

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 907, 23, 5838, 30 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 7, 1, 1, 2, 8, 7, 1, 3, 8, 2, 2, 21 ]

12

true

Family

Large ribosomal subunit protein eL43

Ribosomal_eL43

5

IPR002675

2,675

Large ribosomal subunit protein eL38

Ribosomal_eL38

Family

5,152

false

Ribosomal protein eL38 forms part of the 60S ribosomal subunit [ ]. This family is found in eukaryotes. Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids int...

[ "GO:0003735", "GO:0006412", "GO:0005840" ]

[ "structural constituent of ribosome", "translation", "ribosome" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM", "PANTHER" ]

[ "PF01781", "PTHR10965" ]

[ "Ribosomal_L38e", "" ]

[ 5149, 4895 ]

2

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-BTA-156827", "R-BTA-1799339", "R-BTA-6791226", "R-BTA-72689", "R-BTA-72706", "R-BTA-975956", "R-BTA-975957", "R-CEL-156827", "R-CEL-1799339", "R-CEL-72689", "R-CEL-72706", "R-CEL-975956", "R-CEL-975957", "R-DDI-156827", "R-DDI-1799339", "R-DDI-72689", "R-DDI-72706", "R-DDI-97595...

[ "REACTOME:R-BTA-156827", "REACTOME:R-BTA-1799339", "REACTOME:R-BTA-6791226", "REACTOME:R-BTA-72689", "REACTOME:R-BTA-72706", "REACTOME:R-BTA-975956", "REACTOME:R-BTA-975957", "REACTOME:R-CEL-156827", "REACTOME:R-CEL-1799339", "REACTOME:R-CEL-72689", "REACTOME:R-CEL-72706", "REACTOME:R-CEL-9759...

64

[ "3j6x", "3j6y", "3j77", "3j78", "3j79", "3j7o", "3j7p", "3j7q", "3j7r", "3j92", "3jag", "3jah", "3jai", "3jaj", "3jan", "3jbn", "3jbo", "3jbp", "3jcs", "3jct", "4d5y", "4d67", "4u3m", "4u3n", "4u3u", "4u4n", "4u4o", "4u4q", "4u4r", "4u4u", "4u4y", "4u4z"...

552

[ "PUB00000194", "PUB00007068", "PUB00007069", "PUB00007070" ]

[ "1840484", "11297922", "11290319", "11114498" ]

[ "The primary structure of rat ribosomal protein L38.", "Atomic structures at last: the ribosome in 2000.", "The ribosome in focus.", "The end of the beginning: structural studies of ribosomal proteins." ]

[ 1991, 2001, 2001, 2000 ]

4

[]

0

null

[ "Archaea", "Eukaryota", "marine sediment metagenome" ]

[ 20, 5126, 6 ]

3

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 6, 1, 1, 2, 4, 2, 1, 6, 8, 1, 2, 23 ]

12

true

Family

Large ribosomal subunit protein eL38

Ribosomal_eL38

2

IPR002676

2,676

RimM, N-terminal

RimM_N

Domain

24,579

false

The RimM protein is essential for efficient processing of 16S rRNA [ ]. It was shown to have affinity for free ribosomal 30S subunits but not for 30S subunits in the 70S ribosomes [ ]. RimM contains a characteristic N-terminal domain and a PRC-barrel C-terminal domain, linked by an unstructured region [ ]. The N-termin...

[ "GO:0006364" ]

[ "rRNA processing" ]

[ "biological_process" ]

1

[ "PFAM" ]

[ "PF01782" ]

[ "RimM" ]

[ 24579 ]

1

[]

0

[ "2dog", "2dyi", "2f1l", "2qgg", "3a1p", "3h9n" ]

6

[ "PUB00002319", "PUB00047259" ]

[ "9422595", "17616598" ]

[ "RimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli.", "Structural characterization of the ribosome maturation protein, RimM." ]

[ 1998, 2007 ]

2

[]

0

null

[ "Bacteria", "Escherichia phage vB_EcoM-613R3", "Eukaryota", "candidate division MSBL1 archaeon SCGC-AAA382M17", "unclassified sequences" ]

[ 23287, 1, 815, 1, 475 ]

5

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 4, 1, 3, 12 ]

4

true

Domain

RimM, N-terminal

RimM_N

7

IPR002677

2,677

Large ribosomal subunit protein bL32

Ribosomal_bL32

Family

41,556

false

This entry represents the 50S large ribosomal subunit protein bL32 family. This family is found in prokaryotes and eukaryotic organelles. Structurally well characterised protein as a part of ribosome particle [ , ]. Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons o...

[ "GO:0003735", "GO:0006412", "GO:0015934" ]

[ "structural constituent of ribosome", "translation", "large ribosomal subunit" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "HAMAP", "PFAM", "NCBIFAM" ]

[ "MF_00340", "PF01783", "TIGR01031" ]

[ "Ribosomal_bL32", "Ribosomal_L32p", "rpmF_bact" ]

[ 37950, 39739, 27045 ]

3

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-BTA-5389840", "R-BTA-5419276", "R-BTA-9837999", "R-BTA-9937383", "R-CEL-5389840", "R-CEL-5419276", "R-CEL-9837999", "R-CEL-9937383", "R-HSA-5368286", "R-HSA-5389840", "R-HSA-5419276", "R-HSA-9837999", "R-HSA-9937383", "R-MMU-5389840", "R-MMU-5419276", "R-MMU-9837999", "R-MMU-99373...

[ "REACTOME:R-BTA-5389840", "REACTOME:R-BTA-5419276", "REACTOME:R-BTA-9837999", "REACTOME:R-BTA-9937383", "REACTOME:R-CEL-5389840", "REACTOME:R-CEL-5419276", "REACTOME:R-CEL-9837999", "REACTOME:R-CEL-9937383", "REACTOME:R-HSA-5368286", "REACTOME:R-HSA-5389840", "REACTOME:R-HSA-5419276", "REACTOM...

19

[ "1j5a", "1jzx", "1jzy", "1jzz", "1k01", "1nkw", "1nwx", "1nwy", "1ond", "1sm1", "1vvj", "1vy4", "1vy5", "1vy6", "1vy7", "1xbp", "2j28", "2rdo", "2zjp", "2zjq", "2zjr", "3bbx", "3cf5", "3dll", "3j3v", "3j3w", "3j5l", "3j6b", "3j7y", "3j7z", "3j8g", "3j9m"...

1,259

[ "PUB00006367", "PUB00007068", "PUB00007069", "PUB00007070", "PUB00029251", "PUB00151133" ]

[ "9121443", "11297922", "11290319", "11114498", "12623020", "25132179" ]

[ "Ribosomal protein L32 of Saccharomyces cerevisiae influences both the splicing of its own transcript and the processing of rRNA.", "Atomic structures at last: the ribosome in 2000.", "The ribosome in focus.", "The end of the beginning: structural studies of ribosomal proteins.", "Structural basis for the a...

[ 1997, 2001, 2001, 2000, 2003, 2014 ]

6

[]

[ "IPR044957", "IPR044958" ]

0

2

0

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 2, 23589, 17609, 356 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae ...

[ 12, 1, 1, 1, 2, 1, 1, 6, 2, 1, 1, 8 ]

12

true

Family

Large ribosomal subunit protein bL32

Ribosomal_bL32

4

IPR002678

2,678

DUF34/NIF3

Family

26,107

false

This family includes DUF34/metal-binding proteins from bacteria, NIF3 from budding yeasts and NIF3-like proteins from animals. This entry includes the DUF34/metal-binding protein/NIF3 proteins, which are widely distributed across superkingdoms. They were previously annotated as GTP cyclohydrolase 1 type 2 [ ] and, rece...

[]

0

[ "PFAM", "PANTHER", "NCBIFAM" ]

[ "PF01784", "PTHR13799", "TIGR00486" ]

[ "DUF34_NIF3", "", "YbgI_SA1388" ]

[ 26101, 25471, 22550 ]

3

[]

0

[ "1nmo", "1nmp", "2fyw", "2gx8", "2nyd", "2yyb", "3lnl", "3wsd", "3wse", "3wsf", "3wsg", "3wsh", "3wsi", "4iwg", "4iwm", "9g9u" ]

16

[ "PUB00002954", "PUB00019927", "PUB00070175", "PUB00093692", "PUB00093694", "PUB00100327" ]

[ "8663102", "11124544", "23825549", "23295494", "25243119", "34572495" ]

[ "Transcriptional activation by yeast PDR1p is inhibited by its association with NGG1p/ADA3p.", "Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals.", "Biochemical Characterization of Hypothetical Proteins from Helicobacter pylo...

[ 1996, 2000, 2013, 2013, 2014, 2021 ]

6

[]

[ "IPR017221", "IPR017222" ]

0

2

0

[ "Archaea", "Bacteria", "Eukaryota", "Myoviridae sp. ct2th6", "unclassified sequences" ]

[ 619, 21411, 3740, 1, 336 ]

5

[ "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe...

[ 6, 1, 1, 7, 8, 1, 7, 1, 1 ]

9

true

Family

DUF34/NIF3

1

IPR002679

2,679

Closterovirus coat protein

Closter_coat

Family

3,728

false

This family consist of coat proteins from closterovirus, which belong to the Closteroviridae, which have a positive strand ssRNA genome with no DNA stage during replication. The viral coat protein encapsulates and protects the viral genome. Both the large cp1 and smaller cp2 coat protein originate from the same primary...

[ "GO:0044423" ]

[ "virion component" ]

[ "cellular_component" ]

1

[ "PFAM" ]

[ "PF01785" ]

[ "Closter_coat" ]

[ 3728 ]

1

[]

0

[]

0

[ "PUB00003136" ]

[ "2033386" ]

[ "Molecular cloning and nucleotide sequencing of the coat protein gene of citrus tristeza virus." ]

[ 1991 ]

1

[]

0

null

[ "Eukaryota", "Viruses" ]

[ 3, 3725 ]

2

[]

0

true

Family

Closterovirus coat protein

Closter_coat

5

IPR002680

2,680

Alternative oxidase

AOX

Family

6,670

false

The alternative oxidase (AOX) is an enzyme that forms part of the electron transport chain in mitochondria of different organisms [ , ]. Proteins homologous to the mitochondrial oxidase have also been identified in bacterial genomes [ , ]. The oxidase provides an alternative route for electrons passing through the elec...

[ "GO:0009916" ]

[ "alternative oxidase activity" ]

[ "molecular_function" ]

1

[ "PFAM", "PIRSF", "PANTHER", "CDD" ]

[ "PF01786", "PIRSF005229", "PTHR31803", "cd01053" ]

[ "AOX", "AOX", "", "AOX" ]

[ 6584, 2667, 6473, 4922 ]

4

[ "GP" ]

[ "GenProp1230" ]

[ "GP:GenProp1230" ]

1

[ "3vv9", "3vva", "3w54", "5gn7", "5gn9", "5zdp", "5zdq", "5zdr", "9kun", "9m2a" ]

10

[ "PUB00001878", "PUB00001938", "PUB00009825", "PUB00009826", "PUB00009827", "PUB00073500", "PUB00073501", "PUB00073502", "PUB00073503", "PUB00073504" ]

[ "9426242", "8770590", "11106766", "12215444", "11801238", "15370881", "9698817", "1883834", "15082931", "15087133" ]

[ "Transcript levels of tandem-arranged alternative oxidase genes in rice are increased by low temperature.", "Cloning and analysis of the alternative oxidase gene of Neurospora crassa.", "New insight into the structure and function of the alternative oxidase.", "EPR studies of the mitochondrial alternative oxi...

[ 1997, 1996, 2000, 2002, 2002, 2004, 1998, 1991, 2003, 2004 ]

10

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "metagenomes" ]

[ 649, 5979, 39, 3 ]

4

[ "Arabidopsis thaliana", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 25, 2, 20, 25 ]

4

true

Family

Alternative oxidase

AOX

8

IPR002681

2,681

Coat protein, Ilarvirus

Coat_Ilarvirus

Family

1,158

false

This family consists of various coat proteins from the Ilarviruses which belong to the Bromoviridae, members include Apple mosaic virus and Prune dwarf virus. The Ilarvirus coat protein is required to initiate replication of the viral genome in host plants [ ]. Members of the Bromoviridae have a positive stand ssRNA ge...

[ "GO:0003723", "GO:0006413", "GO:0044423" ]

[ "RNA binding", "translational initiation", "virion component" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM" ]

[ "PF01787" ]

[ "Ilar_coat" ]

[ 1158 ]

1

[]

0

[ "4y6t", "4y6x" ]

2

[ "PUB00003158" ]

[ "7730792" ]

[ "Prunus necrotic ringspot ilarvirus: nucleotide sequence of RNA3 and the relationship to other ilarviruses based on coat protein comparison." ]

[ 1995 ]

1

[]

[ "IPR016405" ]

0

1

0

[ "Bromoviridae" ]

[ 1158 ]

1

[]

0

true

Family

Coat protein, Ilarvirus

Coat_Ilarvirus

2

IPR002682

2,682

Photosystem II PsbJ

PSII_PsbJ

Family

14,439

false

Oxygenic photosynthesis uses two multi-subunit photosystems (I and II) located in the cell membranes of cyanobacteria and in the thylakoid membranes of chloroplasts in plants and algae. Photosystem II (PSII) has a P680 reaction centre containing chlorophyll 'a' that uses light energy to carry out the oxidation (splitti...

[ "GO:0015979", "GO:0009523", "GO:0009539", "GO:0016020" ]

[ "photosynthesis", "photosystem II", "photosystem II reaction center", "membrane" ]

[ "biological_process", "cellular_component", "cellular_component", "cellular_component" ]

4

[ "HAMAP", "PFAM", "PANTHER" ]

[ "MF_01305", "PF01788", "PTHR34812" ]

[ "PSII_PsbJ", "PsbJ", "" ]

[ 13722, 14439, 14118 ]

3

[ "GP" ]

[ "GenProp0661" ]

[ "GP:GenProp0661" ]

1

[ "1s5l", "2axt", "3a0b", "3a0h", "3jcu", "3kzi", "3wu2", "4fby", "4il6", "4ixq", "4ixr", "4pbu", "4pj0", "4rvy", "4tnh", "4tni", "4tnj", "4tnk", "4ub6", "4ub8", "4v62", "4v82", "4yuu", "5b5e", "5b66", "5e79", "5e7c", "5gth", "5gti", "5h2f", "5kaf", "5kai"...

140

[ "PUB00015357", "PUB00015358", "PUB00015359", "PUB00015366", "PUB00015367", "PUB00097583", "PUB00152828" ]

[ "12518057", "15100025", "14871485", "14979726", "14686923", "30076221", "33846594" ]

[ "Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.", "The evolutionary development of the protein complement of photosystem 2.", "The low molecular mass subunits of the photosynthetic supracomplex, photosystem II.", "Photosystem II proteins PsbL and Psb...

[ 2003, 2004, 2004, 2004, 2004, 2018, 2021 ]

7

[]

0

null

[ "Bacteria", "Eukaryota", "marine metagenome" ]

[ 327, 14111, 1 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 5, 4, 2 ]

3

true

Family

Photosystem II PsbJ

PSII_PsbJ

7

IPR002683

2,683

PsbP, C-terminal

PsbP_C

Domain

8,812

false

In PSII, the oxygen-evolving complex (OEC) is responsible for catalysing the splitting of water to O(2) and 4H+. The OEC is composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), wh...

[ "GO:0005509", "GO:0015979", "GO:0009523", "GO:0009654", "GO:0019898" ]

[ "calcium ion binding", "photosynthesis", "photosystem II", "photosystem II oxygen evolving complex", "extrinsic component of membrane" ]

[ "molecular_function", "biological_process", "cellular_component", "cellular_component", "cellular_component" ]

5

[ "PFAM" ]

[ "PF01789" ]

[ "PsbP" ]

[ 8812 ]

1

[ "GP" ]

[ "GenProp0661" ]

[ "GP:GenProp0661" ]

1

[ "1v2b", "2lnj", "2vu4", "2xb3", "3jcu", "4rth", "4rti", "5xnl", "6kac", "7eu3", "7f9o", "7pi0", "7pi5", "7pin", "7piw", "7pnk", "7wff", "7wg5", "8bd3", "8z9d", "9gnw", "9grx", "9hd7" ]

23

[ "PUB00001121", "PUB00002976", "PUB00015357", "PUB00015358", "PUB00015359", "PUB00015369", "PUB00015371", "PUB00097583", "PUB00152828" ]

[ "9039496", "8910540", "12518057", "15100025", "14871485", "15258264", "15031714", "30076221", "33846594" ]

[ "Nucleotide sequence of the psbP gene encoding precursor of 23-kDa polypeptide of oxygen-evolving complex in Arabidopsis thaliana and its expression in the wild-type and a constitutively photomorphogenic mutant.", "Photoactivation and photoinhibition are competing in a mutant of Chlamydomonas reinhardtii lacking ...

[ 1996, 1996, 2003, 2004, 2004, 2004, 2004, 2018, 2021 ]

9

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 30, 695, 8081, 6 ]

4

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 42, 54, 52 ]

3

true

Domain

PsbP, C-terminal

PsbP_C

5

IPR002684

2,684

Biotin synthase/Biotin biosynthesis bifunctional protein BioAB

Biotin_synth/BioAB

Family

20,583

false

This family consists of biotin synthase B-like and bifunctional biotin synthase AB proteins. Biotin synthase works with flavodoxin, S-adenosylmethionine, and possibly cysteine to catalyze the last step of the biotin biosynthetic pathway. The reaction consists of the introduction of a sulphur atom into dethiobiotin, thu...

[ "GO:0004076", "GO:0009102" ]

[ "biotin synthase activity", "biotin biosynthetic process" ]

[ "molecular_function", "biological_process" ]

2

[ "HAMAP", "PANTHER", "NCBIFAM" ]

[ "MF_01694", "PTHR22976", "TIGR00433" ]

[ "BioB", "", "bioB" ]

[ 19569, 20356, 19825 ]

3

[ "EC", "GP", "GP" ]

[ "2.8.1.6", "GenProp0036", "GenProp1377" ]

[ "EC:2.8.1.6", "GP:GenProp0036", "GP:GenProp1377" ]

3

[ "1r30", "8vcw", "8vdw" ]

3

[ "PUB00001863", "PUB00002298", "PUB00007197" ]

[ "8917070", "8763940", "12119030" ]

[ "Two new members of the bio B superfamily: cloning, sequencing and expression of bio B genes of Methylobacillus flagellatum and Corynebacterium glutamicum.", "Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon.", "Biotin synthase is a pyridoxal phosphate-dependent cyst...

[ 1996, 1996, 2002 ]

3

[]

[ "IPR024177" ]

0

1

0

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 500, 17290, 2550, 243 ]

4

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]

[ 4, 1, 1, 2, 1, 1, 14 ]

7

true

Family

Biotin synthase/Biotin biosynthesis bifunctional protein BioAB

Biotin_synth/BioAB

9

IPR002685

2,685

Glycosyl transferase, family 15

Glyco_trans_15

Family

8,663

false

This entry represents a family of fungi mannosyl-transferases involved in N-linked and O-linked glycosylation of proteins. They belong to the glycosyltransferase family 15 ( ). Some of the enzymes in this family have been shown to be involved in O- and N-linked glycan modifications in the Golgi [ ]. The biosynthesis of...

[ "GO:0000030", "GO:0009101", "GO:0016020" ]

[ "mannosyltransferase activity", "glycoprotein biosynthetic process", "membrane" ]

[ "molecular_function", "biological_process", "cellular_component" ]

3

[ "PFAM", "PIRSF", "PANTHER" ]

[ "PF01793", "PIRSF018153", "PTHR31121" ]

[ "Glyco_transf_15", "Glyco_trans_15", "" ]

[ 8564, 4449, 8529 ]

3

[ "CAZY", "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", ...

[ "GT15", "2.4.1.-", "PWY-1901", "PWY-1961", "PWY-1981", "PWY-2021", "PWY-2881", "PWY-2901", "PWY-2902", "PWY-4421", "PWY-4801", "PWY-5094", "PWY-5105", "PWY-5129", "PWY-5139", "PWY-5160", "PWY-5161", "PWY-5268", "PWY-5284", "PWY-5286", "PWY-5310", "PWY-5312", "PWY-5313", ...

[ "CAZY:GT15", "EC:2.4.1.-", "METACYC:PWY-1901", "METACYC:PWY-1961", "METACYC:PWY-1981", "METACYC:PWY-2021", "METACYC:PWY-2881", "METACYC:PWY-2901", "METACYC:PWY-2902", "METACYC:PWY-4421", "METACYC:PWY-4801", "METACYC:PWY-5094", "METACYC:PWY-5105", "METACYC:PWY-5129", "METACYC:PWY-5139", ...

201

[ "1s4n", "1s4o", "1s4p", "5a07", "5a08", "7boo", "7bop" ]

7

[ "PUB00009409", "PUB00019631" ]

[ "9334165", "9878809" ]

[ "A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities.", "The KTR and MNN1 mannosyltransferase families of Saccharomyces cerevisiae." ]

[ 1997, 1999 ]

2

[]

0

null

[ "Bacteria", "Eukaryota", "Natronomonas aquatica", "Viruses", "metagenomes" ]

[ 8, 8633, 1, 4, 17 ]

5

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 5, 9, 6 ]

3

true

Family

Glycosyl transferase, family 15

Glyco_trans_15

4

IPR002686

2,686

Transposase IS200-like

Transposase_17

Domain

39,236

false

Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This entry represents a domain found in transposases for IS200 from Escherichia coli [ ].

[ "GO:0003677", "GO:0004803", "GO:0006313" ]

[ "DNA binding", "transposase activity", "DNA transposition" ]

[ "molecular_function", "molecular_function", "biological_process" ]

3

[ "PFAM", "SMART" ]

[ "PF01797", "SM01321" ]

[ "Y1_Tnp", "Y1_Tnp" ]

[ 31605, 35855 ]

2

[]

0

[ "2a6m", "2a6o", "2ec2", "2f4f", "2f5g", "2fyx", "2vhg", "2vic", "2vih", "2vju", "2vjv", "2xm3", "2xma", "2xo6", "2xqc", "4er8", "6fi8" ]

17

[ "PUB00034636" ]

[ "10471738" ]

[ "Repression of IS200 transposase synthesis by RNA secondary structures." ]

[ 1999 ]

1

[]

0

null

[ "Archaea", "Bacteria", "Caudoviricetes", "Eukaryota", "unclassified sequences" ]

[ 977, 37487, 29, 20, 723 ]

5

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

Transposase IS200-like

Transposase_17

1

IPR002687

2,687

Nop domain

Nop_dom

Domain

17,908

false

This entry represents the Nop domain. The Nop domain is present in various pre-RNA processing ribonucleoproteins (RNP): Eukaryotic Prp31, part of a tri-snRNP complex. It is involved in pre-mRNA splicing. Eukaryotic Nucleolar proteins 56 and 58 (Nop56 and Nop58), components of box C/D small nucleolar ribonucleoprotein (...

[]

0

[ "PFAM", "PROFILE" ]

[ "PF01798", "PS51358" ]

[ "Nop", "NOP" ]

[ 17866, 16631 ]

2

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-CEL-6791226", "R-DDI-4570464", "R-DDI-6791226", "R-HSA-390471", "R-HSA-4570464", "R-HSA-6790901", "R-HSA-6791226", "R-HSA-72163", "R-MMU-4570464", "R-MMU-6791226", "R-MMU-72163", "R-RNO-4570464", "R-RNO-6791226", "R-SCE-4570464", "R-SCE-6791226", "R-SPO-4570464", "R-SPO-6791226" ]

[ "REACTOME:R-CEL-6791226", "REACTOME:R-DDI-4570464", "REACTOME:R-DDI-6791226", "REACTOME:R-HSA-390471", "REACTOME:R-HSA-4570464", "REACTOME:R-HSA-6790901", "REACTOME:R-HSA-6791226", "REACTOME:R-HSA-72163", "REACTOME:R-MMU-4570464", "REACTOME:R-MMU-6791226", "REACTOME:R-MMU-72163", "REACTOME:R-R...

17

[ "1nt2", "2nnw", "2ozb", "3gqu", "3gqx", "3icx", "3id5", "3id6", "3jcm", "3jcr", "3nmu", "3nvi", "3nvk", "3nvm", "3pla", "3siu", "3siv", "4by9", "5gan", "5gap", "5gin", "5gio", "5gip", "5jpq", "5nrl", "5o9z", "5oql", "5wlc", "5wyj", "5wyk", "5zwm", "5zwo"...

103

[ "PUB00003706", "PUB00027813", "PUB00044450", "PUB00044451", "PUB00062919", "PUB00062921", "PUB00090272", "PUB00090527", "PUB00090687", "PUB00097816", "PUB00097817", "PUB00103405", "PUB00103406" ]

[ "9372940", "12598892", "11867543", "12444105", "17412961", "11545739", "28781166", "28530653", "17636026", "12777385", "19620283", "21683323", "22492559" ]

[ "Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.", "Structure and function of archaeal box C/D sRNP core proteins.", "Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP form...

[ 1997, 2003, 2002, 2002, 2007, 2001, 2017, 2017, 2007, 2003, 2009, 2011, 2012 ]

13

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "metagenomes" ]

[ 942, 11, 16908, 47 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 34, 3, 6, 8, 16, 16, 3, 19, 11, 3, 3, 54 ]

12

true

Domain

Nop domain

Nop_dom

6

IPR002690

2,690

Herpesvirus capsid protein 2

Herpes_capsid_2

Family

851

false

This family consist of various capsid proteins from members of the Herpesviridae. The capsid protein 2 (formerly known as VP23) in Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) forms a triplex together with VP19C these fit between and link together adjacent capsomers as formed by VP5 and VP26 [ ]. VP3 alon...

[ "GO:0005198", "GO:0019028" ]

[ "structural molecule activity", "viral capsid" ]

[ "molecular_function", "cellular_component" ]

2

[ "HAMAP", "PFAM" ]

[ "MF_04019", "PF01802" ]

[ "HSV_TRX2", "Herpes_V23" ]

[ 292, 851 ]

2

[ "REACTOME", "REACTOME" ]

[ "R-HSA-9609690", "R-HSA-9610379" ]

[ "REACTOME:R-HSA-9609690", "REACTOME:R-HSA-9610379" ]

2

[ "5vku", "5zap", "5zz8", "6b43", "6cgr", "6lgl", "6lgn", "6m6g", "6m6h", "6m6i", "6nhj", "6odm", "6ppb", "6ppd", "6pph", "6q1f", "6w19", "6w2d", "6w2e", "7bqx", "7br7", "7br8", "7bsi", "7bw6", "7et3", "7etj", "7eto", "7fj1", "7fj3", "7liv", "8hex", "8hey"...

45

[ "PUB00003549" ]

[ "10400780" ]

[ "Roles of triplex and scaffolding proteins in herpes simplex virus type 1 capsid formation suggested by structures of recombinant particles." ]

[ 1999 ]

1

[]

0

null

[ "Herpesvirales", "Homo sapiens" ]

[ 850, 1 ]

2

[ "Homo sapiens" ]

[ 1 ]

1

true

Family

Herpesvirus capsid protein 2

Herpes_capsid_2

2

IPR002692

2,692

Penicillin/GL-7-ACA/AHL/aculeacin-A acylase

S45

Family

18,537

false

This entry represents a number of acylases which all belong to MEROPS peptidase family S45 (clan PB). Penicillin G acylase precursor and cephalosporin acylase precursor, more precisely termed glutaryl-7-aminocephalosporanic acid (GL-7-ACA) acylase, are self-cleaving proteins that spontaneously form the heterodimeric su...

[ "GO:0016787", "GO:0017000" ]

[ "hydrolase activity", "antibiotic biosynthetic process" ]

[ "molecular_function", "biological_process" ]

2

[ "PFAM", "PANTHER" ]

[ "PF01804", "PTHR34218" ]

[ "Penicil_amidase", "" ]

[ 18534, 18329 ]

2

[ "EC" ]

[ "3.5.1.97" ]

[ "EC:3.5.1.97" ]

1

[ "1ai4", "1ai5", "1ai6", "1ai7", "1ajn", "1ajp", "1ajq", "1cp9", "1e3a", "1fm2", "1fxh", "1fxv", "1ghd", "1gk0", "1gk1", "1gk9", "1gkf", "1gm7", "1gm8", "1gm9", "1h2g", "1jvz", "1jw0", "1jx9", "1k5q", "1k5s", "1k7d", "1kec", "1keh", "1or0", "1pnk", "1pnl"...

84

[ "PUB00064260" ]

[ "17586674" ]

[ "Newly discovered penicillin acylase activity of aculeacin A acylase from Actinoplanes utahensis." ]

[ 2007 ]

1

[]

[ "IPR014395" ]

0

1

0

[ "Archaea", "Bacteria", "Eukaryota", "Pseudomonas phage YMC12/01/R24", "unclassified sequences" ]

[ 311, 17547, 275, 1, 403 ]

5

[]

0

true

Family

Penicillin/GL-7-ACA/AHL/aculeacin-A acylase

S45

3

IPR002693

2,693

Paramyxovirinae P phosphoprotein C-terminal domain

Paramyxo_PProtein_C

Domain

549

false

The subfamily Paramyxovirinae of the family Paramyxoviridae now contains as main genera the Rubulaviruses, avulaviruses, respiroviruses, Henipavirus-es and morbilliviruses. Protein P is the best characterised, structurally of the replicative complex of N, P and L proteins and consists of two functionally distinct moiet...

[ "GO:0003723", "GO:0003968", "GO:0006351", "GO:0019079" ]

[ "RNA binding", "RNA-directed RNA polymerase activity", "DNA-templated transcription", "viral genome replication" ]

[ "molecular_function", "molecular_function", "biological_process", "biological_process" ]

4

[ "PFAM" ]

[ "PF01806" ]

[ "Paramyxo_P" ]

[ 549 ]

1

[]

0

[ "1ezj", "1r4g", "8kdb", "8kdc" ]

4

[ "PUB00003548" ]

[ "10400742" ]

[ "Dissection of individual functions of the Sendai virus phosphoprotein in transcription." ]

[ 1999 ]

1

[]

0

null

[ "Paramyxoviridae" ]

[ 549 ]

1

[]

0

true

Domain

Paramyxovirinae P phosphoprotein C-terminal domain

Paramyxo_PProtein_C

7

IPR002694

2,694

Zinc finger, CHC2-type

Znf_CHC2

Domain

34,881

false

This entry represents CycHisCysCys (CHC2) type zinc finger domains, which are found in bacteria and viruses. Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not...

[ "GO:0003677", "GO:0003899", "GO:0008270", "GO:0006260" ]

[ "DNA binding", "DNA-directed RNA polymerase activity", "zinc ion binding", "DNA replication" ]

[ "molecular_function", "molecular_function", "molecular_function", "biological_process" ]

4

[ "PFAM", "SMART" ]

[ "PF01807", "SM00400" ]

[ "Zn_ribbon_DnaG", "ZnF_CHCC" ]

[ 34636, 32582 ]

2

[ "EC" ]

[ "2.7.7.101" ]

[ "EC:2.7.7.101" ]

1

[ "1d0q", "2au3" ]

2

[ "PUB00014077", "PUB00035804", "PUB00035805", "PUB00035806", "PUB00035807", "PUB00035812" ]

[ "12665246", "17210253", "15963892", "15718139", "10529348", "11179890" ]

[ "Zinc fingers--folds for many occasions.", "Sticky fingers: zinc-fingers as protein-recognition motifs.", "Multiple modes of RNA recognition by zinc finger proteins.", "Zinc finger proteins: getting a grip on RNA.", "Zinc finger peptides for the regulation of gene expression.", "Zinc finger proteins: new ...

[ 2002, 2007, 2005, 2005, 1999, 2001 ]

6

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 13, 33078, 118, 864, 808 ]

5

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

Zinc finger, CHC2-type

Znf_CHC2

3

IPR002695

2,695

Bifunctional purine biosynthesis protein PurH-like

PurH-like

Family

33,273

false

This is a family of bifunctional enzymes catalysing the last two steps in de novo purine biosynthesis. The bifunctional enzyme is found in both prokaryotes and eukaryotes. The second last step is catalysed by 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), this enzyme catalyses the formylatio...

[ "GO:0003937", "GO:0004643", "GO:0006164" ]

[ "IMP cyclohydrolase activity", "phosphoribosylaminoimidazolecarboxamide formyltransferase activity", "purine nucleotide biosynthetic process" ]

[ "molecular_function", "molecular_function", "biological_process" ]

3

[ "HAMAP", "PFAM", "PIRSF", "PANTHER", "SMART", "NCBIFAM" ]

[ "MF_00139", "PF01808", "PIRSF000414", "PTHR11692", "SM00798", "TIGR00355" ]

[ "PurH", "AICARFT_IMPCHas", "AICARFT_IMPCHas", "", "AICARFT_IMPCHas", "purH" ]

[ 27243, 32653, 28267, 33154, 31723, 25818 ]

6

[ "EC", "EC", "GP", "GP", "GP", "GP", "GP", "METACYC", "METACYC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "2.1.2.3", "3.5.4.10", "GenProp0110", "GenProp1406", "GenProp1592", "GenProp1730", "GenProp1757", "PWY-6123", "PWY-6124", "PWY-7234", "R-BTA-73817", "R-DDI-73817", "R-GGA-419140", "R-HSA-73817", "R-HSA-9725370", "R-MMU-73817", "R-RNO-73817", "R-SCE-73817", "R-SPO-73817" ]

[ "EC:2.1.2.3", "EC:3.5.4.10", "GP:GenProp0110", "GP:GenProp1406", "GP:GenProp1592", "GP:GenProp1730", "GP:GenProp1757", "METACYC:PWY-6123", "METACYC:PWY-6124", "METACYC:PWY-7234", "REACTOME:R-BTA-73817", "REACTOME:R-DDI-73817", "REACTOME:R-GGA-419140", "REACTOME:R-HSA-73817", "REACTOME:R-...

19

[ "1g8m", "1m9n", "1oz0", "1p4r", "1pkx", "1pl0", "1thz", "1zcz", "2b1g", "2b1i", "2iu0", "2iu3", "3zzm", "4a1o", "4ehi", "5uy8", "5uz0", "6nko", "7mgq", "9ou7" ]

20

[ "PUB00001876" ]

[ "9332377" ]

[ "Molecular cloning and expression of a rat cDNA encoding 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase." ]

[ 1997 ]

1

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 544, 26306, 5599, 19, 805 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 7, 3, 2, 2, 1, 7, 2, 1, 4, 3, 2, 1, 12 ]

13

true

Family

Bifunctional purine biosynthesis protein PurH-like

PurH-like

6

IPR002696

2,696

Membrane protein insertion efficiency factor YidD-like

Membr_insert_effic_factor_YidD

Family

23,418

false

This family consists of membrane insertion efficiency factor proteins, such as YidD which may be involved in insertion of integral membrane proteins into the membrane [ ]. They contain three conserved cysteine residues.

[]

0

[ "HAMAP", "PFAM", "PANTHER", "SMART", "NCBIFAM" ]

[ "MF_00386", "PF01809", "PTHR33383", "SM01234", "TIGR00278" ]

[ "UPF0161_YidD", "YidD", "", "Haemolytic", "" ]

[ 21587, 23173, 22417, 23232, 23163 ]

5

[]

0

[]

0

[ "PUB00064882" ]

[ "21803992" ]

[ "Role for Escherichia coli YidD in membrane protein insertion." ]

[ 2011 ]

1

[]

0

null

[ "Bacteria", "Caudoviricetes", "Eukaryota", "Methanomicrobiales", "unclassified sequences" ]

[ 22338, 2, 709, 3, 366 ]

5

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 2, 1, 8, 4 ]

4

true

Family

Membrane protein insertion efficiency factor YidD-like

Membr_insert_effic_factor_YidD

5

IPR002698

2,698

5-formyltetrahydrofolate cyclo-ligase

FTHF_cligase

Family

34,241

false

5-formyltetrahydrofolate cyclo-ligase or methenyl-THF synthetase catalyses the interchange of 5-formyltetrahydrofolate (5-FTHF) to 5-10-methenyltetrahydrofolate, this requires ATP and Mg 2 [ ]. 5-FTHF is used in chemotherapy where it is clinically known as Leucovorin [ ]. This entry also includes the 5-formyltetrahydro...

[]

0

[ "PFAM", "PIRSF", "PANTHER", "PANTHER", "NCBIFAM" ]

[ "PF01812", "PIRSF006806", "PTHR13017", "PTHR23407", "TIGR02727" ]

[ "5-FTHF_cyc-lig", "FTHF_cligase", "", "", "MTHFS_bact" ]

[ 33855, 25925, 4097, 29770, 27551 ]

5

[ "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "GenProp1356", "R-CEL-196757", "R-HSA-196757", "R-MMU-196757", "R-SCE-196757", "R-SPO-196757" ]

[ "GP:GenProp1356", "REACTOME:R-CEL-196757", "REACTOME:R-HSA-196757", "REACTOME:R-MMU-196757", "REACTOME:R-SCE-196757", "REACTOME:R-SPO-196757" ]

6

[ "1sbq", "1sou", "1u3f", "1u3g", "1wkc", "1ydm", "2jcb", "3hxt", "3hy3", "3hy4", "3hy6" ]

11

[ "PUB00001860", "PUB00002860", "PUB00070331" ]

[ "8522195", "8034591", "21538139" ]

[ "Cloning and characterization of the human 5,10-methenyltetrahydrofolate synthetase-encoding cDNA.", "Primary structure and tetrahydropteroylglutamate binding site of rabbit liver cytosolic 5,10-methenyltetrahydrofolate synthetase.", "A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comp...

[ 1995, 1994, 2011 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Mimivirus LCMiAC02", "unclassified sequences" ]

[ 625, 25524, 7607, 1, 484 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...

[ 9, 1, 8, 5, 1, 20, 12, 1, 11, 12, 1, 1, 12 ]

13

true

Family

5-formyltetrahydrofolate cyclo-ligase

FTHF_cligase

7

IPR002699

2,699

ATPase, V1 complex, subunit D

V_ATPase_D

Family

9,903

false

This is a family of D subunits from various ATP synthases, including V-type H+ transporting and Na+ transporting [ ]. This family is found in eukaryota, bacteria and archaea [ , ]. The V-type ATPase can use a proton gradient to synthesize ATP, but the primary biological role is to acidify some compartment, such as yeas...

[ "GO:0046961" ]

[ "proton-transporting ATPase activity, rotational mechanism" ]

[ "molecular_function" ]

1

[ "HAMAP", "PFAM", "PANTHER", "NCBIFAM" ]

[ "MF_00271", "PF01813", "PTHR11671", "TIGR00309" ]

[ "ATP_synth_D_arch", "ATP-synt_D", "", "V_ATPase_subD" ]

[ 3828, 9888, 9306, 8927 ]

4

[ "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", ...

[ "GenProp0629", "R-CEL-1222556", "R-CEL-6798695", "R-CEL-77387", "R-CEL-917977", "R-CEL-9639288", "R-CEL-983712", "R-DDI-1222556", "R-DDI-6798695", "R-DDI-77387", "R-DDI-917977", "R-DDI-9639288", "R-DME-1222556", "R-DME-6798695", "R-DME-77387", "R-DME-917977", "R-DME-9639288", "R-DM...

[ "GP:GenProp0629", "REACTOME:R-CEL-1222556", "REACTOME:R-CEL-6798695", "REACTOME:R-CEL-77387", "REACTOME:R-CEL-917977", "REACTOME:R-CEL-9639288", "REACTOME:R-CEL-983712", "REACTOME:R-DDI-1222556", "REACTOME:R-DDI-6798695", "REACTOME:R-DDI-77387", "REACTOME:R-DDI-917977", "REACTOME:R-DDI-9639288...

40

[ "3a5c", "3a5d", "3aon", "3j0j", "3j9t", "3j9u", "3j9v", "3vr4", "3vr5", "3vr6", "3w3a", "4rnd", "5bw9", "5d80", "5gar", "5gas", "5knb", "5knc", "5knd", "5tsj", "5vox", "5voy", "5voz", "5y5x", "5y5y", "5y5z", "5y60", "6ly8", "6o7v", "6o7w", "6o7x", "6qum"...

129

[ "PUB00004863", "PUB00005718", "PUB00009752", "PUB00020603", "PUB00020604", "PUB00020609", "PUB00020618", "PUB00059237", "PUB00059238", "PUB00068786", "PUB00068787", "PUB00068788", "PUB00068789", "PUB00099348" ]

[ "7831318", "8157629", "11309608", "15473999", "15078220", "15629643", "15168615", "10788522", "9177272", "20450191", "18937357", "1385979", "9741106", "33065002" ]

[ "A bovine cDNA and a yeast gene (VMA8) encoding the subunit D of the vacuolar H(+)-ATPase.", "Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae.", "Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase....

[ 1995, 1994, 2001, 2004, 2004, 2005, 2004, 2000, 1997, 2010, 2008, 1992, 1998, 2020 ]

14

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Fadolivirus FV1/VV64", "unclassified sequences" ]

[ 985, 3357, 5374, 1, 186 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 3, 1, 2, 5, 14, 6, 1, 3, 8, 1, 1, 8 ]

12

true

Family

ATPase, V1 complex, subunit D

V_ATPase_D

1

IPR002701

2,701

Chorismate mutase II, prokaryotic-type

CM_II_prokaryot

Domain

38,062

false

This entry represents the CM type 2 domain, mainly from prokaryotes. It does not include the CM from plants and or Baker's yeast. Chorismate mutase (CM) is a regulatory enzyme ( ) required for biosynthesis of the aromatic amino acids phenylalanine and tyrosine. CM catalyzes the Claisen rearrangement of chorismate to pr...

[ "GO:0004106", "GO:0046417" ]

[ "chorismate mutase activity", "chorismate metabolic process" ]

[ "molecular_function", "biological_process" ]

2

[ "PFAM", "PROFILE", "SMART" ]

[ "PF01817", "PS51168", "SM00830" ]

[ "CM_2", "CHORISMATE_MUT_2", "CM_2" ]

[ 37859, 34327, 34437 ]

3

[ "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "PROSITEDOC" ]

[ "5.4.99.5", "PWY-3461", "PWY-3462", "PWY-6120", "PWY-6627", "PWY-7626", "PDOC51167" ]

[ "EC:5.4.99.5", "METACYC:PWY-3461", "METACYC:PWY-3462", "METACYC:PWY-6120", "METACYC:PWY-6627", "METACYC:PWY-7626", "PROSITEDOC:PDOC51167" ]

7

[ "1csm", "1ecm", "1ybz", "2ao2", "2csm", "2d8d", "2d8e", "2f6l", "2fp1", "2fp2", "2gbb", "2gtv", "2h9c", "2h9d", "2qbv", "2vkl", "2w19", "2w1a", "3csm", "3hgw", "3hgx", "3nvt", "3rem", "3ret", "3rmi", "3tfc", "4csm", "4ppu", "4ppv", "5ckx", "5csm", "5gmu"...

55

[ "PUB00003018", "PUB00011060", "PUB00011063", "PUB00011068", "PUB00013816" ]

[ "9642265", "11528003", "9384560", "9665711", "8335631" ]

[ "Tyrosine and tryptophan act through the same binding site at the dimer interface of yeast chorismate mutase.", "Allosteric regulation of catalytic activity: Escherichia coli aspartate transcarbamoylase versus yeast chorismate mutase.", "Mechanisms of catalysis and allosteric regulation of yeast chorismate muta...

[ 1998, 2001, 1997, 1998, 1993 ]

5

[]

[ "IPR010950", "IPR010952", "IPR010954", "IPR010957", "IPR010958", "IPR011277", "IPR011279" ]

0

7

0

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 821, 32910, 3904, 20, 407 ]

5

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]

[ 10, 2, 1, 6, 1, 1, 23 ]

7

true

Domain

Chorismate mutase II, prokaryotic-type

CM_II_prokaryot

1