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Primary Urban Health Centre should be for a population of:
[ "30,000", "50,000", "10,000", "1,000,000" ]
B
URBAN HEALTH CARE DELIVERY MODEL :- Community level: Community outreach services. Sub-primary level: Swasthya chowki 1 Swasthya chowki per 10,000 population. 1 ANM + 1 Community health worker. Primary level: I Primary urban health Centre (PUHC) 1 PUHC/UHC per 50,000 (1 per 25000-30000 in slums). Referral level: Public ...
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Positive Rinne test indicates
[ "AC > BC", "BC > AC", "BC = AC", "None" ]
A
In this test air conduction of the ear is compared with its bone conduction. It is a test for conductive deafness. Rinne Positive: AC > BC Rinne Negative: BC > AC (conductive deafness in that ear) Ref: Dhingra; 6th Edition; pg no 22
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As per WHO guidelines, iodine deficiency disorders are endemic in the community when prevalence of goitre in school age children is more than –
[ "1%", "5%", "10%", "15%" ]
B
null
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Aminoacyl tRNA synthetase is required for all except:
[ "Lysine", "Cysteine", "Methionine", "Hydroxyproline" ]
D
Some proteins contain additional amino acids that arise due to post-translational modification of existing amino acyl residues. Examples: Vitamin C mediated hydroxylation of proline and peptidyl lysine to 4-hydroxyproline and 5-hydroxylysine Vitamin K mediated g-carboxylation of glutamate Methylation Formylation Acetyl...
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Staphylococcus can cause
[ "Pharyngitis", "Tuberculosis", "Migraine", "Dermatitis" ]
A
Staphylococcal infections are the most common bacterial infections and range from tril to fatal. The common pyogenic staphylococcal infections are: Skin and soft tissue infections: Folliculitis, furuncle, abscess, wound infections, carbuncle, impetigo, paronychia and less often cellulitis. 2. Musculoskeletal: Osteomyel...
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Accommodation is due to -
[ "Relaxation of ciliary' muscles", "Contraction of ciliary'1 muscles", "Contraction of dilator pupillae", "None" ]
B
Ans. is 'b' i.e., Contraction of ciliary muscles Accommodationo Accommodation of the eye refers to the act of physiologically adjusting crystalline lens elements to alter the refractive powrer and bring objects that are closer to the eye into sharp focus,o Our eyes have been provided with a unique mechanism by which we...
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LEIGH disease is due to the accumulation of-
[ "Glycogen", "Pyrodoxine", "Sphingomyelin", "None" ]
D
Ans. is 'None'
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The characteristic feature of apoptosis on light microscopy is:
[ "Cellular swelling", "Nuclear compaction", "Intact cell membrane", "Cytoplasmic eosinophlia" ]
B
Ans. (b) Nuclear compaction(Ref: Robbins 9th/pg 53)Here student gets confused in 2 options b and c..On light microscopy, most characteristic feature is condensation of nuclear chromatin and not intactness of cell membraneIntact cell membrane and lack of inflammation differentiates apoptosis from necrosis.
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Anesthectic agent with least minimum alveolar concentration (MAC):
[ "Nitrous oxide", "Isoflurane", "Desflurane", "Xenon" ]
B
Ans: (b) IsofluraneRef: Stoelting's Pharmacology and Physiology in Anesthetic Practice, 4th editionMAC (MINIMUM ALVEOLAR CONCENTRATION)MAC is the concentration of inhalational agent in alveoli at 1 atm that prevents skeletal muscle movement in response to a supra-maximal painful stimulus (surgical skin incision) in 50%...
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Which of following clostridia is non-invasive:
[ "Clostridium novyi", "Clostridium botulinum", "Clostridium perfringens", "Clostridium tetani" ]
B
Ans. is. 'b' i. e. Clostridium botulinum
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The enzyme used to "flush" the sticky ends of DNA is
[ "Klenow fragment", "Polynucleotide kinase", "Alkaline phosphatase", "Primase" ]
A
Flushing of sticky ends means to remove the sticky ends (3' overhangs) for producing blunt-ended DNA (no overhangs). The sticky ends has 3' overhangs which can be digested with Klenow fragment (has 3'-5' exonuclease activity) to produce blunt-end DNA. Tool Role Type II restriction enzymes Cleaves DNA at specific sites ...
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IL-1 is activated by
[ "Caspase 1", "Caspase 3", "Caspase 5", "Caspase 8" ]
A
* Pyroptosis is associated with release of cytokine IL 1 * Microbial products that enter the cytoplasm of the cell are recognised by cytoplasmic immune receptors and activates a multiprotein complex called INFLAMMASOME * Inflammasome will activate CASPASE 1 (also called Interleukin 1 beta conveing enzyme) and releases ...
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Which of the following is not a content of buccal space?
[ "Buccal branches of the facial nerve", "Stenson duct", "Transverse facial artery and vein", "Buccal fat pad" ]
A
Facial nerve is not present in buccal space.
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Cutaneous lesions may be produced by the following mycobacteria except-
[ "M. intracellulare", "M. Leprae", "M. marinum", "M. tuberculosis" ]
A
. Ans. is 'a' i.e., M. intracellulare Principal types of oppounist mycobacterial disease in man and the usual causative agents. Diseases Usual causative agent Lymphadenopathy M. avium complex M. scrofulaceum Skin lesion Post-trauma abscess M. chelonae M.fouitum M. terrae Swimming pool granuloma M.marinum Buruli ulcer M...
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The ideal method for restoring a fractured tooth is
[ "Open faced stainless steel crown", "Reattachment of fractured tooth segment", "Strip crown", "Composite resin restoration" ]
B
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Brodie -Trendlenburg test demonstrates?
[ "Mid - thigh perforation", "Deep vein thrombosis", "Sapheno -- femoral incompetence", "Calf perforators" ]
C
Ans. is 'c' i.e., Sapheno-femoral incompetence
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Double rise of temperature in 24 hrs is seen in case of -
[ "Kala azar", "Malaria", "TB", "Hodgkin's lymphoma" ]
A
Double rise of temperature in 24 hrs is seen in case of Kala azar. Option 1, 2, 3, 4 1. L. donovani donovani, infection of the classic kala-azar ("black sickness") or dumdum fever type occurs in many pas of Asia, Africa and Southeast Asia. 2. Kala-Azar Fever: In the early stages of the disease, there is a mild irregula...
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An adult presented with hemetemesis and upper abdominal pain. Endoscopy revealed a growth at the pyloric antrum of the stomach. CT scan showed growth involving the pyloric antrum without infiltration or invasion into surrounding structures and no evidence of distant metastasis. At Laparotomy neoplastic growth was obser...
[ "Closure of the abdomen", "Antrectomy and vagotomy", "Paial Gastrectomy + Distal pancreatectomy", "Paial Gastrectomy + Distal pancreatectomy + splenectomy" ]
C
Gastric cancer have various treatment modalities. Based on this scenario, this patient falls in to T4N0M0, i.e., tumor spreading to adjacent tissues (pancreas), no regional lymphnodes involvement and no metastasis will have to go paial gastrectomy and distal pancreatectomy. Ref: Surgery in the Multimodal Management of ...
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The demographic goal of Net Reproduction Rate is equal to one (NPR=1) can be achieved only if the Couple Protection Rate exceeds
[ "40%", "50%", "60%", "70%" ]
C
(C) 60%[?]Couple protection rate (CPR)oCouple protection rate (CPR) is an indicator of the prevalence of contraceptive practice in the community.oIt is defined as the per cent of eligible couples effectively protected against childbirth by one or the other approved methods of family planning, viz. sterilization, IUD, c...
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Hypokalemia in an infant may be due to all of the following except -
[ "Adrenal tumor", "Adrenal tumor", "Thiazide therapy", "Diarrhea" ]
B
Ans. is 'b' i.e., Acute Renal failure Hypokalemia o Hypokalemia is defined as serum potassium values of less than 3.5 meq/L. Impoant causes of hypokalemia in children Spurious Decreased intake Renal losses o Leukemia o Aorexia nervosa o Distal A Transcellular shift o External loss o Proximal A o Alkalosis o Diarrhea o ...
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Benzodiazepine (BZD) receptor antagonist is -
[ "Nalorphine", "Carbamazepine", "Naloxone", "Flumazenil" ]
D
Ans. is 'd' i.e., Flumazenil o Flumazenil is a benzodiazepene analogue which competes with BZD agonists as well as inverse agonists for the BZD receptor and reverses their depressant or stimulant effects respectively.o It also antagonizes the action of Zolpidem, Zopiclone and Zopeplon as these drugs also act on BZD sit...
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A woman aged 60 yrs suffers a fall; her lower limb is extended and externally rotated; likely diagnosis is:
[ "Neck of femur fracture", "Interochanteric femur fracture", "Posterior dislocation of hip", "Anterior dislocation of hip" ]
A
An aged woman presents with extended & externally rotated lower limb following a fall indicates fracture of neck of femur. Ref: Essential Ohopedics By Maheshwari 2nd Edition, Page 197 ; Apley's System of Ohopaedics and Fractures, 8th Edition, Page 685
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A patient with tubercular pleural effusion falls under category of WHO grading of TB -a) Ib) IIc) IIId) IV
[ "a", "ac", "ad", "b" ]
B
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Most common side effect of DH Ps calcium channe blockers is -
[ "Headache", "Constipation", "Diarrhoea", "Muscle cramps" ]
A
Ans. is `a' i.e., Headache o The most common side effects caused by the Ca" channel antagonists, paicularly the dihydropyridines, are due to excessive vasodilator. Symptoms include dizziness, hypotension, headache, flushing, digital dysesthesia, and nausea.
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Ailurophobia is
[ "Fear of height", "Fear of water", "Fear of cats", "Fear of strangers" ]
C
Acrophobia : Fear of height. Hydrophobia : Fear of water. Ailurophobia : Fear of cats. Xenophobia : Fear of strangers.
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In the treatment of which of the following poisoning cholinesterase reactivator is used?
[ "Curare", "Organophosphorus compounds", "Amanita muscaria", "All of the above" ]
B
Ans. b (Organophosphorus compounds) (Ref. KDT 5th/pg. 100, 105)The commonly used cholinesterase inhibitors fall into three chemical groups:# Simple alcohols bearing a quaternary ammonium group, e g., edrophonium;# Carbamic acid esters of alcohols bearing quaternary or tertiary ammonium groups (carbamates, eg, neostigmi...
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In Endodontics Endotec is used
[ "with lateral condensation and heated gutta percha", "with cold lateral compaction", "with vertical compaction", "with Chloro Percha Technique" ]
A
null
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Allen's test is useful in evaluating which of the following conditions?
[ "Digital blood flow", "Presence of cervical rib", "Integrity of palmar arch", "Thoracic outlet compression" ]
C
Allen's test is performed to check the patency of radial and ulnar aeries at the wrist. Thus this test is useful in evaluating the integrity of the palmar arch. In this test, the examiner compresses both the radial and ulnar aeries at the wrist and then asks the patient to flex and extend the fingers repetitively. Afte...
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An elderly male presents with headache, recurrent infections and multiple punched out lytic lesions of x-ray skull. The investigation that will best help in establishing a diagnosis is:
[ "Protein Electrophoresis", "Serum calcium", "Alkaline phosphatase levels", "Acid phosphatase levels" ]
A
Answer is A (Protein Electrophoresis) Presence of symptoms of hyperviscocity syndrome (Headache), recurrent infections (ineffective defense against infections) and multiple punched out lytic lesions in the skull suggest a diagnosis of Multiple myeloma Protein electrophoresis will help demonstrate a characteristic 'M sp...
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Normal capacity of renal pelvis is
[ "7 ml", "12 ml", "15 ml", "20 ml" ]
A
The renal pelvis is roughly pyramidal, with the base facing the parenchyma and the apex funneling down into the ureter. It usually has a capacity of 3 to 10 mL of urine. ref : campbell - walsh urology 11th ed , chapter 42 , pg no : 973
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Human immunoglobulin A can be described by which of the following statements?
[ "It is the predominant immunoglobulin in plasma", "It exists in four subclasses, of which IgA 2 is predominant", "It can prevent attachment of microorganisms to epithelial cell membranes", "It is prominent early in the immune response and is the major class of antibody in cold agglutinins" ]
C
Immunoglobulin A is the predominant immunoglobulin in body secretions (IgG is predominant in serum). Each secretory IgA molecule is a dimer consisting of a secretory component and a J chain. The secretory component, a protein of molecular weight 70,000, is synthesized by epithelial cells and facilitates IgA transpo acr...
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The most common cause of Addison's disease is -
[ "Autoimmune adrenalitis", "Meningococcal septicemia", "Malignancy", "Tuberculosis" ]
A
Most common cause (60%-70%) of primary adrenocorticol insufficiency (Addison'discases) is autoimmune adrenelitis. Other common cause are. Tuberculosis → Most common cause of Addison's disease in India. AIDS Metastatic cancers
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Gamekeepers thumb is
[ "Thumb metacarpophalangeal joint ulnar collateral ligament rupture", "Thumb metacarpophalangeal joint radial collateral ligament rupture", "Thumb interphalangeal joint ulnar collateral ligament rupture", "Thumb interphalangeal joint radial collateral ligament rupture" ]
A
Injury to the thumb metacarpophalangeal joint ulnar collateral ligament is commonly referred to as gamekeeper thumb or skier's thumb, although the original "gamekeeper" description (Campbell, 1955) referred to an attritional ulnar collate-earl ligament injurySnow skiing accidents and falls on an outstretched hand with ...
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True regarding GERD is all except -
[ "Avoid coffee & tea", "Transient lower esophageal relaxation", "Lower esophageal sphincter length and its pressure is impoant", "Proton pump inhibitor is the treatment of choice" ]
C
Gastro-oesophageal reflux disease Gastro-oesophageal reflux resulting in heaburn affects approximately 30% of the general population. Pathophysiology Occasional episodes of gastro-oesophageal reflux are common in healthy individuals. Reflux is normally followed by oesophageal peristaltic waves that efficiently clear th...
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Hess's (Tourniquet) test is a feature of -
[ "Idiopathic Thrombocytopenic Purpura (I.T.P)", "Secondary thrombocytopenia", "Allergic purpura", "Senile purpura" ]
A
null
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Hyperpigmentation is seen in all except
[ "peutz jeghers syndrome", "addison's disease", "cushing's sydrome", "Aright syndrome" ]
C
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Which of the following has strong affinity for hemoglobin and acts in blood to act as "mop-up" molecule to bind hemoglobin?
[ "Ferritin", "Transferrin", "Haptoglobin", "Albumin" ]
C
Ans. c (Haptoglobin). (Ref. Robbin, Pathology, 7th ed., 624; Harrison, Internal medicine 15th ed., s608)Free Hb in plasma is promptly bounded by an alphal globulin, the haptoglobin that acts as 'mop-up' producing a complex that is rapidly cleared by mononuclear phagocyte system, thus preventing excretion in urine; henc...
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Glomerulonephritis associated with AIDS is-
[ "Focal segmental GN", "PSGN", "MPGN", "Membranous GN" ]
A
null
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Slit shaped nipple seen in
[ "Duct ectasia", "Duct pappiloma", "Paget's disease", "CA breast" ]
A
Answer- A. Duct ectasiaDuct ectasia is dilatation of lactiferous ducts associated with periductal inflammation.Chronic inflammation and scarring will lead to indrawing and slit-shaped inversion of the nipple.If secondary infection supervenes, a mammary duct fistula can also develop.
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The nerve responsible for Cremasteric reflex is:
[ "Hypogastric nerve", "Genito femoral nerve", "Ilioinguinal nerve", "All of the above" ]
B
Genito femoral nerve
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MHC CLASS III CODES for all except –
[ "complement C3", "properdin", "TNF –alpha", "heat shock proteins." ]
A
null
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All are impoant laboratory features of hemolytic anemia , EXCEPT:
[ "Normal AST", "Elevated urobilinogen in stool", "Reduced haptoglobin", "Macrocytes in blood smear" ]
A
The laboratory features of Hemolytic anemia: Increase in unconjugated bilirubin and aspaate transaminase (AST) Urobilinogen increased in both urine and stool. Hemoglobinuria (often associated with hemosiderinuria) in intravascular hemolysis Lactate dehydrogenase (LDH) is increased Increase in reticulocytes Increased me...
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The active principal in calotropis is all, except
[ "Calotoxin", "Calactin", "Uscharin", "Bhilawanol" ]
D
Bhilawanol is an active principle of Semecarpaus anacardium. Active principles of calotropis: Uscharin, calotoxin and calotropin
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Feature of slow sand filter
[ "Fit in a little space", "Filter is cleaned by back washing", "Can be handled by less killed person", "Used in Big cities" ]
C
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Which of the following estimating the burden of a disease in the community is
[ "Disease specific mortality", "Proportional mortality rate", "Maternal mortality rate", "Child mortality rate" ]
B
(Proportional mortality rate) (23 - Park 19th) (25, 54-Park 20th)Proportional mortality rate - The simplest measures of estimating the burden of a disease in the community is proportional mortality rate i.e. - the proportion of all deaths currently attributed to it.* The proportional mortality rate from communicable di...
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Rice contains -
[ "6 % protein", "12 % protein", "14 % protein", "0.6 % protein" ]
A
The protein content of rice varies from 6-9 percent. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 21ST EDITION. PAGE NO - 627
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Which one of the following life-threatening congenital anomalies in the newborn presents with polyhydramnios, aspiration pneumonia, excessive salivation and difficulty in passing a nasogastric tube?
[ "Gastroschisis", "Diaphragmatic hernia", "Tracheo-esophageal fistula", "Choanal atresia" ]
C
c. Tracheo-esophageal fistula(Ref: Nelson's 20/e p 1783, Ghai 8/e p 176)Presence of polyhydramnios, aspiration pneumonia, excessive salivation and difficulty in passing a nasogastric tube all point towards a diagnosis of tracheoesophageal fistula, which is usually accompanied by esophageal atresia.Esophageal atresia (E...
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A patient developed breathlessness and chest pain, on second postoperative day after a total hip replacement. Echo-cardiography showed right ventricular dilatation and tricuspid regurgitation. What is the most likely diagnosis-
[ "Acute MI", "Pulmonary embolism", "Hypotensive shock", "Cardiac tamponate" ]
B
*Onset of chest pain and breathlessness, together with echocardiographic evidence of right ventricular dilatation and tricispid regurgitation after a high risk procedure like total hip replacement suggests a diagnosis of pulmonary embolism. REF:Campbell's 11th/e Chapter-7
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A child with pyoderma becomes toxic and presents with respiratory distress. His chest radiograph shows patchy areas of consolidation and multiple bilateral thin-walled air containing cysts. The most likely etiological agent in this case is –
[ "Mycobacterium tuberculosis", "Staphylococcus aureus", "Mycobacterium avium intracellulare", "Pneumocystis carinii" ]
B
Pneumonia with pneumatoceles (multiple thin-walled breaths of air containing cysts) is s/o staphylococcal pneumonia. Clinical features of staphylococcal pneumonia The illness usually follows upper respiratory tract infection, pyoderma or another associated purulent disease. Besides the usual features of pneumonia chi...
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True about denaturation of proteins is all except:
[ "Unfolding occurs", "Disruption of secondary structure occurs", "Sequence of amino acids remain the same", "Biological activity is retained" ]
D
D i.e. Biological activity is retained
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Nerve of Latarjet is seen in
[ "Thorax", "Neck", "Stomach", "Hea" ]
C
The nerve of Latarjet or the posterior nerve of the lesser curvature is a branch of the anterior vagal trunk which supplies the pylorus. BD CHAURASIA S HUMAN ANATOMY Vol 3
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Nerve supply of the tympanic membrane is by the
[ "Auriculotemporal", "Lesser occipital", "Greater occipital", "Parasympathetic ganglion" ]
A
A i.e. Aurico-temporal nerve
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Which type of refractive error is seen in keratoconus-
[ "Irregular astigmatism", "Regular astigmatism", "Myopia", "Hypermetropia" ]
A
Ans. is 'a' i.e., Irregular astigmatism. Examination findings o The hallmark of keratoconus is central or paracentral stromal thinning, apical protrusion of the anterior cornea and irregular astigmatism. The cornea thins near the center and progressively bulges forwards, with the apex of cone always being slightly belo...
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A soft contact lens users has corneal keratitis cause is
[ "Acanthamoeba-ulcer", "Erosion of cornea", "Pseudomonas infection", "Herpes infection" ]
C
C i.e. Pseudomonas infection
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Localized formation of dentin on the pulp-dentin border formed in reaction to caries or restorative procedures is known as
[ "Tertiary dentin", "Secondary dentin", "Primary dentin", "Interglobular dentin" ]
A
null
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A neonate with respiratory distress and the following chest X ray most likely has:
[ "Cystic fibrosis", "CLE", "CCAM", "Pneumonia" ]
B
null
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Which of the following is not a structural gene of HIV -
[ "Gag", "Polio", "ENV", "Tat" ]
D
tat is a nonstructural and regulatory gene of HIV REF:ANANTHANARAYANAN TEXT BOOK OF MICROBIOLOGY 9EDITION PGNO.572
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Prolonged exposure to noise levels greater than the following can impair hearing permanently:
[ "40 decibels", "85 decibels", "100 decibels", "140 decibels" ]
C
A noise of 90 dB SPL, 8 hours a day for 5 days per week is the maximum safe limit as recommended by ministry of labour, govt of India-rules under factories act.
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Urgent reversal of warfarin induced bleeding can be done by the administration of
[ "Cryoprecipitate", "Platelet concentrates", "Fresh frozen plasma", "Packed red blood cells" ]
C
Fresh frozen plasma contains clotting factors . Hence given immediately in warfarin induced bleeding. From essential of medical pharmacology K D Tripati 7th edition Page no 620
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A 70-year-old patient presents with dizziness and headache followed by left sided hemiparesis with right eye dilatation and ptosis. Most probable blood vessel damaged is:
[ "Middle cerebral artery", "Anterior communicating artery", "Posterior cerebral artery", "Basilar artery" ]
C
Ans: (c) Posterior cerebral arteryRef: Adams and Victor's Principles of Neurology, 10th edition, Page 804; Localisation in Clinical Neurology, 6th edition, Chapter 105EponymSiteCranial nerves involvedTracts involvedSignsArteries involvedWeber SyndromeBase of midbrainIIICorticospinal tractOculomotor palsy with crossed h...
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Which of the following is not an indicator for disability?
[ "HALE", "DALY", "Pearl index", "Sullivan's index" ]
C
Pearl index is a measure of effectiveness of a contraceptive method. It is expressed as failure rate per 100 woman years and is not related to disability. Note: HALE - Health Adjusted Life Expectancy DALY - Disability Adjusted Life Years Ref: Park's Textbook of Preventive Medicine, 17th Edition, Pages 22, 351.
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Zika Virus is transmitted by
[ "Anopheles", "Culex", "Aedes", "Mansonia" ]
C
Zika virus is transmitted to people primarily through the bite of an infected Aedes species mosquitoRef: Park; Pg. No: 293
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Atopic Dermatitis is diagnosed by:
[ "Patch test", "Wood Lamp", "Clinical Examination", "#NAME?" ]
C
C i.e. Clinical Examination Itch (or pruritis)Q is a major diagnostic criteria whereas, Denny Morgan infra orbital fold is a minor criteria for diagnosis of atopic dermatitis. Atopic dermatitis most commonly involves flexural surfaces like antecubital and popliteal fossa Q. However, in infantile phase, face and extenso...
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A one month old baby presents with frequent vomiting and failure to thrive, There are features of moderate dehydration, Blood sodium is 122 m Eq/i and potassium is 6.1 in Eq/L The most likely diagnosis is
[ "Gitelman syndrome", "Bater syndrome", "21 hydroxylase deficiency", "11 B-hydroxylase deficiency" ]
C
21 Hydroxylase deficiency - (A) Salt losing form of CALL due to associated with aldosterone deficiency, these patients presents with severe vomiting, and vascular collapse. Hyponatreniia hypochloremia and hyperkalemia (B) A Cryptic form of CAH is asymptomatic - presents with menstrual irregularities, acne, hirsutism * ...
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Lymphogranuloma venerum is caused by -
[ "Chlamydia trachomatis", "Calymmatobacter granulomatis", "Haemophilus ducreyii", "Treponema pallidum" ]
A
Ans. is 'a' i.e., Chlamydia trachomatis
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A 42-year-old woman presents with a diffuse swelling in front of the neck. Thyroid function tests are within normal limits. A fine-needle biopsy reveals malignant cells. The tumor is excised and examined. The tumour cells are positive for calcitonin on immunohistochemistry. What is the appropriate pathologic diagnosis?
[ "Anaplastic carcinoma", "Follicular carcinoma", "Medullary carcinoma", "Papillary carcinoma" ]
C
Medullary carcinoma thyroid microscopic features: Composed of polygonal to spindle-shaped cells, which may form nests, trabeculae, and even follicles. Small, more anaplastic cells are present in some tumors and may be the predominant cell type. Amyloid deposits derived from calcitonin polypeptides are present in the st...
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Quality indicator of MCH services ?
[ "IMR", "MMR", "CMR", "None" ]
A
Ans. is 'a' i.e., IMR IMR is best indicator for:? Health status of a community. Level of living. Effectiveness of MCH services. IMR is second best indicator of socioeconomic status of country (under 5 moality rate is more refined indicator for socioeconomic status).
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Central dot sign is seen in?
[ "Primary sclerosing cholangitis", "Liver Hamaoma", "Caroli's disease", "Polycystic liver disease" ]
C
Ans is c i.e. Caroli's disease Caroli's disease is a rare congenital abnormality in which there is communicating cavernous ectasia of the intrahepatic biliary ducts. Caroli's disease is equivalent to type V choledochal cyst. It is commonly associated with congenital hepatic fibrosis and cystic lesions of the kidney.Pat...
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Devesh is working as a CEO in a company. He has a traveling job. He is a known diabetic, controlled on oral hypoglycemic drugs. On his recent visit to the doctor, his blood pressure was found to be 164/102 mm Hg. Most suitable drug for this patient should be?
[ "Propanolol", "Enalapril", "Clonidine", "Hydrochlohiazide" ]
B
ACE inhibitors (Enalapril) are safe and effective agents in diabetic patients with hypeension. Thiazides and b-blockers (Propanolol) are contraindicated in diabetic patients. As the patient has frequent travelling job, he is likely to miss the doses. Therefore, clonidine should be avoided to prevent rebound hypeension.
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Amongst various current criteria for FUO (Fever of Unknown origin), one relates to body temperature =
[ "98.4deg F", "99.4deg F", "100deg F", "101deg F" ]
D
Ans. d (101deg F). (Ref: Harrison's 17th edition, P. 130).PUO/FUO# Petersdorf and Beeson (1961)# Temperature > 101deg F (38.3degF) on several occasions# Duration of fever > 3 weeks# Failure to reach diagnosis despite inpatient investigations for 1 week.Also Remember:Neutropenic FUO# Neutrophil count < 500/cmmHIV Associ...
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What is meant by suppositious child -
[ "Second born of a twin pregnancy", "Child born out of wedlock", "Child rear up by a woman & She claims the child", "Heterozygous mother & father" ]
C
Ans. is 'c' i.e., Child rear up by a woman & She claims the child Suppositious child Suppositious child means a factitious child. o Women may pretend pregnancy as well as delivery & later produces a child as if it is her own. She may substitute a living male child for a dead child or for a living female child born of h...
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Recurrant interosseous aery is a branch of
[ "Posterior interosseous aery", "Anterior interosseous aery", "Radial aery", "Ulnar aery" ]
A
Near its origin , posterior interosseous aery gives off interosseous recurrent aery which runs upwards , and ends by anastomosing with middle collateral aery behind lateral epicondyle . B D Chaurasia 7th edition Page no : 113
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All can be used for systematic fungal infections except:
[ "Ketoconazole", "Fluconazole", "Amphotericin B", "Griseofulvin" ]
D
Griseofulvin: It was one of the early antibiotics extracted from Penicillium griseofulvum. However, because of lack of antibacterial activity, little attention was paid to it: clinical utility in dermatophytosis was demonstrated only around 1960. Griseofulvin is active against most dermatophytes, including Epidermophyt...
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Mitsuda reaction is read after:
[ "3 days", "3 hours", "3 weeks", "3 months" ]
C
Lepromin Test is type IV HSR It is a PROGNOSTIC test not a diagnostic test 2 reactions are seen in Lepromin test- Early Reaction/ Fernandez- Erythema and induration develops in 24-48 hours and remain for 3-5 days and it is read after 3 days Late Reaction/Mitsuda Reaction- It stas in 1-2 weeks, reaching a peak in 4 week...
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Which of the following structures pass through aoic hiatus?
[ "Thoracic duct and azygos vein", "Thoracic duct and gastric aery", "Vagus nerve with oesophagus", "Aorla with oesophagus" ]
A
The aoic hiatus situated at the level of T12 veebra. Structures passing through aoic hiatus along with aoa are:Thoracic ductAzygos veinHemiazygos vein
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The earliest muscle to be involved in dermatomyositis is
[ "Deltoid", "Gluteal", "Lumbricals", "Quadriceps" ]
D
Dermatomyositis (DM) is a long-term inflammatory disorder which affects muscles. Its symptoms are generally a skin rash and worsening muscle weakness over time.These may occur suddenly or develop over months.Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity.Complications may include...
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WHO ORS contains -
[ "Sodium chloride 2.5 g", "Potassium chloride 1.5 g", "Glucose 20g", "Shift of water from ECF to ICF" ]
B
Ans. is 'b' i.e., Potassium chloride-1.5 gm Because of the improved effectiveness of reduced osmolarity ORS solution, WHO and UNICEF are recommending that countries manufacture and use the following formulation in place of the previously recommended ORS solution.
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Bell clapper testis predisposes to:
[ "Torsion testis", "Varicocele", "Cancer of testis", "Hydrocele" ]
A
Testicular torsion is a condition in which testicle twists in such a way that the blood supply is compromised. Abnormalities which lead to torsion of the testis: 1. High investment of tunica vaginalis causing the testis to hang within the tunica like a clapper in the bell bilaterally. 2. Inversion of the testis. 3. Sep...
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Apical lung carcinoma commonly manifests as: September 2009
[ "Pleural effusion", "Pericardial involvement", "Homer's syndrome", "Tumour obstruction of the airway" ]
C
Ans. C: Homer's syndrome The bulk of a true Pancoast tumor is extrathoracic, originating in an extreme peripheral location with a plaque like extension over the lung apex and principally involving the chest wall structures rather than the underlying lung parenchyma. Bronchogenic carcinomas occurring in the narrow confi...
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IUCD is contraindicated in :
[ "Anemia", "Hypeension", "Infection", "All of the above" ]
C
Infection
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Posterolateral lesions of ventral spinal cord leads to
[ "Pyramidal signs", "loss of joint sense", "Loss of pressure,touch", "Loss of pain temperature" ]
C
(C) Loss of pressure, touch
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Drug of choice for prophylaxis of TB is?(DNB 2012-section-1)
[ "Rifampicin", "Isoniazid", "Pyrizinamide", "Streptomycin" ]
B
Ans. (b) IsoniazidRef .KDT 6/e / 740-743
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Matrix vesicles play important role in the mineralization of
[ "Dentin", "Enamel", "Pulp", "Periodontal ligament" ]
A
null
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A 62-year-old man is discovered to have hyperlipidemia on screening tests after a routine physical examination. Laboratory studies show total serum cholesterol of 285 mg/dL, LDL of 215 mg/dL, HDL of 38 mg/dL, and triglycerides of 300 mg/ dL. This patient is most at risk of developing an aneurysm in which of the followi...
[ "Abdominal aorta", "Ascending aorta", "Circle of Willis", "Coronary artery" ]
A
Abdominal aortic aneurysms, which are defined as an increase in aortic diameter of 50% or more, are the most frequent aneurysms, usually developing after the age of 50 years. The most common cause of these abdominal aortic aneurysms is atherosclerosis. Aneurysms secondary to atherosclerosis are less common in the other...
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Most variable absorption is seen with which route
[ "oral", "Intramuscular", "Intravenous", "Per rectal" ]
A
Ref-Goodman and gillman 12th/20 Oral route has maximum variability in absorption
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This incidental finding on ultrasound abdomen is suggestive of:
[ "Gall bladder stone", "Gall bladder polyp", "Adenomyomatosis", "Xanthgranulomatous cholecystitis" ]
C
Adenomyomatosis: Image shows: Diamond ring sign / comet tail aefact / V - shaped aefact Hyperplasia in muscularis & hyperproliferation of mucosa in gall bladder. Rokitansky-Aschoff sinuses are deep and there is deposition of Cholesterol crystal, when ultrasound is performed it looks like a ring. Rx: Symptomatic gall st...
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Embryologically cerebellum is derived from:
[ "Prosencephalon", "Mesencephalon", "Rhombencephalon", "Metancephalon" ]
D
Metancephalon
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True statement concerning placenta pre is
[ "Its incidence decreases with maternal age", "The initial hemorrhage is usually painless and rarely fatal", "Management no longer includes a double setup", "Vaginal examination should be done immediately on suspicion of placenta pre" ]
B
The initial haemorrhage in placenta pre is usually painless and rarely fatal.If the fetus is premature and if haemorrhage is not severe, vaginal examination of a woman suspected of having placenta pre frequently can be delayed until 37 weeks gestation; this delay in the potentially hazardous examination reduces the ris...
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Which is an uricosuric drug-
[ "Allopurinol", "Probenecid", "Indomethacin", "Aspirin" ]
B
Ans. is 'b' i.e., Probenecid Uricosuric drugs are probenacid, sulfinpyrazone and benzbromarone.
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A 52 year old lady with a vesicovaginal fistula after abdominal hysterectomy is not responding to conservative management. Most useful and impoant next investigation is:
[ "Triple Swab Test", "Urine culture", "Cystoscopy", "IVP" ]
C
The most valuable investigation in an established case of a vesicovaginal fistula should be cystoscopy. Ref: Female Pelvic Health and Reconstructive Surgery By Carlin and Leong, 1st Edition; Minute Obstetrics and Gynecology consult, 2008, Page 210; Urogynecology and Female Pelvic Reconstructive Surgery : Just the Facts...
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Nocturnal Enuresis is occurrence of involuntary voiding at night in a child more than
[ "2 1/2 yrs", "3 1/2 yrs", "4 yrs", "5 yrs" ]
D
Ans. (d) 5yrs* OP ghai states enuresis as urinary incontinence beyond the age of 4 years for daytime and 6 years for night-time enuresis.* It is said to be present if it occurs twice per week for 3 consecutive months.* Most of children attain complete bladder control by age of 5 years* The prevalence of enuresis is 7% ...
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Tigroid Pattern on MRI is associated with which of the following disease?
[ "Krabbe disease", "Niemann Pick disease", "Alexander disease", "Metachromatic Leukodystrophy" ]
D
Metachromatic Leukodystrophy: Is a deep white matter leukodystrophy with sparing of subcoical U-fibers and lamellated or Tigroid pattern of the involved white matter. It is associated with Aryl Sulfatase deficiency. Characterized by bilateral symmetrical confluent areas of periventricular deep white matter signal chang...
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H. pylori causes:
[ "Type A Gastritis", "Type B Gastritis", "Autoimmune", "Allergic gastritis" ]
B
Chronic Gastritis: Type A Type B Autoimmune etiology Circulating antobodies to the parietal cell results in the atrophy of the parietal cell mass, resulting in hypochlorhydria and ultimately achlorydria Associated with pernicious anemia Primarily involves body and fundus Associated with H. pylori infection Primarily in...
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Most common cancer of anus:
[ "Adenocarcinoma", "Squamous cell CA", "Basal cell CA", "Melanoma" ]
B
Ans. (b) Squamous cell CARef: Sabiston 19th ed. /1405-06B CARCINOMA ANAL CANAL* Carcinomas arising proximal to the (dentate line) pectinate line are known as basaloid,cuboidal, or cloacogenic tumors; about one-third of anal cancers have this histologic pattern.* Malignancies arising distal to the pectinate line have sq...
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Prolonged salmonella septicemia is caused by -
[ "S. enteritidis", "S. cholerae-suis", "S. typhimurium", "S. typhi" ]
B
null
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Dosage of benzyl penicillin in treatment of primary syphilis is :
[ "1.2 MU single i.m.", "1.2 MU single i.v.", "2.4 MU single i.m.", "4.8 MU single i.m." ]
C
null
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Zinc dose in 8 months infants -
[ "10 mg/kg x 10 days", "20 mg/kg x 10 days", "10 mg/kg x 14 days", "20 mg/kg x 14 days" ]
D
Ans. is 'd' l.e., 20 mg/kg x 14 days
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fibrinoid necrosis is senn all the following except ?
[ "malignant hypeension", "acute rheumatic fever", "polyahropathy", "polyairitis nodosa" ]
C
Fibrinoid necrosis : alSo called "fibrinoid degeneration" It appears as strongly eosinophilic, reflexible small granules, pieces or amorphous materials, in the wall of blood vessel or in connective tissue. The original structure is destroyed. It can be seen in rheumatic fever, allergic vasculitis and other immune compl...
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False about Peutz jegher syndrome
[ "Most Common site is small intestine", "polypectomy on colonoscopy is treatment of choice", "Hamaomatous polyp", "Hyperplastic polyp" ]
D
Peutz- Jeghers Syndrome Rare autosomal dominant disorder Defined by presence of multiple gastrointestinal hamaomatous polyps and mucocutaneous hyperpigmentation, increased risk of malignancies including cancer of lung, colon, pancreas, breast, ovary, uterus and testes. Intestinal polyps are most common in small intesti...
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All are true about secretin except
[ "Inhibits gastric emptying", "Increases bicarbonate rich pancreatic secretion", "Potentiates action of CCK", "| ses bile salt & bile acids" ]
D
Actions of secretin: Increases bicarbonate-rich pancreatic secretion. Stimulates bile secretion. Potentiates effect of CCK on pancreas. It causes contraction of pyloric sphincter delaying gastric emptying. Ref: Medical physiology, Indu Khurana
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