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BI 224436 was an investigational new drug under development for the treatment of HIV infection. BI 224436 is the first non-catalytic site integrase inhibitor (NCINI). It inhibits HIV replication via binding to a conserved allosteric pocket of the HIV integrase enzyme . This makes the drug distinct in its mechanism o... | https://en.wikipedia.org/wiki/C27H26N2O4 |
1,3-Bis(diphenylphosphino)propane ( dppp ) is an organophosphorus compound with the formula Ph 2 P(CH 2 ) 3 PPh 2 . The compound is a white solid that is soluble in organic solvents. It is slightly air-sensitive , degrading in air to the phosphine oxide . It is classified as a diphosphine ligand in coordination chemis... | https://en.wikipedia.org/wiki/C27H26P2 |
JD5037 is an antiobesity drug candidate which acts as a peripherally-restricted cannabinoid inverse agonist at CB 1 receptors . It is very selective for the CB 1 subtype, with a Ki of 0.35nM, >700-fold higher affinity than it has for CB 2 receptors. [ 1 ]
In animal studies, JD5037 does not readily cross the blood brai... | https://en.wikipedia.org/wiki/C27H27Cl2N5O3S |
Remibrutinib is a small molecule drug that acts as a selective and covalent Bruton's tyrosine kinase (BTK) inhibitor. It is in development for the treatment of chronic spontaneous urticaria . [ 1 ] [ 2 ] In November 2023, Novartis announced that the compound "demonstrated clinically meaningful and statistically signifi... | https://en.wikipedia.org/wiki/C27H27F2N5O3 |
AM-1221 is a drug that acts as a potent and selective agonist for the cannabinoid receptor CB 2 , with a K i of 0.28 nM at CB 2 and 52.3 nM at the CB 1 receptor, giving it around 180 times selectivity for CB 2 . [ 1 ] The 2- methyl and 6- nitro groups on the indole ring both tend to increase CB 2 affinity while general... | https://en.wikipedia.org/wiki/C27H27N3O3 |
Tezosentan is a non-selective ET A and ET B receptor antagonist . [ 1 ] It acts as a vasodilator and was designed by Actelion as a therapy for patients with acute heart failure . However, studies showed that tezosentan did not improve dyspnea or reduce the risk of fatal or nonfatal cardiovascular events. [ 2 ]
This d... | https://en.wikipedia.org/wiki/C27H27N9O6S |
NJK14047 is a drug which acts as a selective inhibitor of the enzyme p38 mitogen-activated protein kinase (p38 MAPK). It has antiviral and antiinflammatory effects and was originally developed as a potential treatment for inflammatory lung conditions such as influenza . Subsequent research has also shown promise for va... | https://en.wikipedia.org/wiki/C27H27NO5 |
Bromothymol blue (also known as bromothymol sulfone phthalein and BTB ) is a pH indicator . It is mostly used in applications that require measuring substances that would have a relatively neutral pH (near 7). A common use is for measuring the presence of carbonic acid in a liquid. It is typically sold in solid form as... | https://en.wikipedia.org/wiki/C27H28Br2O5S |
Crinecerfont , sold under the brand name Crenessity , is a medication used for the treatment of congenital adrenal hyperplasia . [ 1 ] It is a corticotropin-releasing factor type 1 receptor (CRF1R) antagonist developed to treat classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD). [ 1 ] It is... | https://en.wikipedia.org/wiki/C27H28ClFN2OS |
Nitromifene ( INN Tooltip International Nonproprietary Name ; also as the citrate salt nitromifene citrate ( USAN Tooltip United States Adopted Name ), developmental code names CI-628 , CN-5518 , CN-55945 ) is a nonsteroidal selective estrogen receptor modulator (SERM) related to triphenylethylenes like tamoxifen that ... | https://en.wikipedia.org/wiki/C27H28N2O4 |
Yuremamine is a phytoindole alkaloid which was isolated from the bark of Mimosa tenuiflora in 2005, and erroneously assigned a pyrrolo[1,2-a]indole structure that was thought to represent a new class of indole alkaloids . [ 2 ] However, in 2015, the bioinspired total synthesis of yuremamine revealed its structure to be... | https://en.wikipedia.org/wiki/C27H28N2O6 |
Cilnidipine is a calcium channel blocker . Cilnidipine is approved for use in Japan, China, India, Nepal, and Korea for hypertension .
It is a calcium antagonist accompanied with L -type and N -type calcium channel blocking functions. Unlike other calcium antagonists, cilnidipine can act on the N -type calcium channel... | https://en.wikipedia.org/wiki/C27H28N2O7 |
MT-7716 is an experimental opioid drug that could potentially be used in the treatment of alcohol addiction.
Unlike most opioids, MT-7716 does not appear to act through delta, kappa and mu opioid receptors, but instead is an agonist of the nociceptin receptor . [ 1 ]
A study has shown that MT-7716 was able to decreas... | https://en.wikipedia.org/wiki/C27H28N4O2 |
Bisbenzimide ( Hoechst 33342 ) is an organic compound used as a fluorescent stain for DNA in molecular biology applications. [ 1 ] Several related chemical compounds are used for similar purposes and are collectively called Hoechst stains .
Bisbenzimide tends to bind to adenine – thymine -rich regions of DNA and can d... | https://en.wikipedia.org/wiki/C27H28N6O |
Ethinylestradiol benzoate , or 17α-ethynylestradiol 3-benzoate , is a synthetic estrogen and estrogen ester – specifically, the C3 benzoate ester of ethinylestradiol – which was first described in the late 1930s and was never marketed. [ 1 ] [ 2 ]
This article about a steroid is a stub . You can help Wikipedia by expa... | https://en.wikipedia.org/wiki/C27H28O3 |
Y-320 is an orally active immunomodulator , and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC 50 of 20 to 60 nM. [ 1 ]
Y-320 also inhibits the production of IFN-γ and TNF-α by mouse CD4 T cells stimulated with IL-15, CXCL12 , and anti-CD3 mAb.
Y-320 (0.3-3 mg/kg p.o.) ameliorates collagen-ind... | https://en.wikipedia.org/wiki/C27H29ClN6O2 |
Allisartan isoproxil is an antihypertensive pharmaceutical drug. [ 1 ] [ 2 ] [ 3 ] It belongs to the angiotensin II receptor blocker class of drugs. It is an esterified prodrug , [ 2 ] and its metabolism results in the formation of a single metabolite, losartan carboxylic acid (EXP3174), an oxidized form of losartan .... | https://en.wikipedia.org/wiki/C27H29ClN6O5 |
Fluticasone furoate , sold under the brand name Flonase Sensimist among others, is a corticosteroid for the treatment of non-allergic and allergic rhinitis administered by a nasal spray . [ 9 ] It is also available as an inhaled corticosteroid to help prevent and control symptoms of asthma . It is derived from cortisol... | https://en.wikipedia.org/wiki/C27H29F3O6S |
Mozavaptan ( INN ) is a vasopressin receptor antagonist marketed by Otsuka . In Japan, it was approved in October 2006 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH) due to ADH producing tumors.
This antihypertensive -related article is a stub . You can help... | https://en.wikipedia.org/wiki/C27H29N3O2 |
1T-AL-LAD is a psychedelic lysergamide derivative which has been sold as a designer drug , first reported in April 2024. It is believed to act as a prodrug for AL-LAD in a similar manner to how 1P-LSD acts as a prodrug for LSD . [ 1 ] | https://en.wikipedia.org/wiki/C27H29N3O2S |
NNC 63-0532 is a nociceptoid drug used in scientific research . It acts as a potent and selective agonist for the nociceptin receptor , also known as the ORL-1 ( opiate receptor-like 1 ) receptor. [ 1 ] [ 2 ]
The function of this receptor is not well understood, but it is believed to play a role in disorders like pain... | https://en.wikipedia.org/wiki/C27H29N3O3 |
MRS-1706 is a selective inverse agonist for the adenosine A 2B receptor . [ 1 ] It inhibits release of interleukins and has an antiinflammatory effect. [ 2 ] [ 3 ]
This antineoplastic or immunomodulatory drug article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H29N5O5 |
Bosentan , sold under the brand name Tracleer among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery hypertension (PAH). [ 3 ] [ 4 ]
Bosentan is available as film-coated tablets (62.5 mg or 125 mg) or as dispersable tablets for oral suspension (32 mg). [ 3 ]
Bosent... | https://en.wikipedia.org/wiki/C27H29N5O6S |
Trecadrine ( INN Tooltip International Nonproprietary Name ) is a drug that was originally developed as an anti-ulcer agent but was found to act as a β 3 -adrenergic receptor agonist with potential anti-obesity and anti-diabetic properties. [ 2 ] [ 3 ] [ 1 ] [ 4 ] It is selective for the β 3 -adrenergic receptor, lacki... | https://en.wikipedia.org/wiki/C27H29NO |
Daunorubicin , also known as daunomycin , is a chemotherapy medication used to treat cancer . [ 2 ] Specifically it is used for acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), and Kaposi's sarcoma . [ 2 ] It is administered by injection into a vein . [ 2 ] A liposom... | https://en.wikipedia.org/wiki/C27H29NO10 |
Sulforhodamine B or Kiton Red 620 ( C 27 H 30 N 2 O 7 S 2 ) is a fluorescent dye with uses spanning from laser-induced fluorescence (LIF) to the quantification of cellular proteins of cultured cells . This red solid dye is very water-soluble . [ 1 ]
The dye has maximal absorbance at 565 nm light and maximal fluoresce... | https://en.wikipedia.org/wiki/C27H30N2O7S2 |
Darexaban ( YM150 ) is a direct inhibitor of factor Xa created by Astellas Pharma . [ 1 ] It is an experimental drug that acts as an anticoagulant and antithrombotic to prevent venous thromboembolism after a major orthopaedic surgery, stroke in patients with atrial fibrillation [ 2 ] and possibly ischemic events in acu... | https://en.wikipedia.org/wiki/C27H30N4O4 |
The molecular formula C 27 H 30 O 15 , molar mass: 594.52 g/mol, exact mass: 594.15847 u, may refer to: | https://en.wikipedia.org/wiki/C27H30O15 |
Rutin ( rutoside , quercetin-3-O-rutinoside or sophorin ) is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α- L -rhamnopyranosyl-(1→6)-β- D -glucopyranose). It is a flavonoid glycoside found in a wide variety of plants, including citrus .
Rutin is one of the phenolic compounds found in ... | https://en.wikipedia.org/wiki/C27H30O16 |
The molecular formula C 27 H 30 O 17 (molar mass: 626 g/mol, exact mass: 626.1482994 u) may refer to: | https://en.wikipedia.org/wiki/C27H30O17 |
Estradiol acetylsalicylate , or estradiol 3-acetylsalicylate , is a synthetic estrogen and estrogen ester – specifically, the C3 acetylsalicylic acid (aspirin) ester of estradiol – which was described in the late 1980s and was never marketed. [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ] In dogs, the oral bioavailability of estradiol ... | https://en.wikipedia.org/wiki/C27H30O5 |
Thymol blue (thymolsulfonephthalein) is a brownish-green or reddish-brown crystalline powder that is used as a pH indicator . It is insoluble in water but soluble in alcohol and dilute alkali solutions.
It transitions from red to yellow at pH 1.2–2.8 and from yellow to blue at pH 8.0–9.6. It is usually a component of ... | https://en.wikipedia.org/wiki/C27H30O5S |
The molecular formula C 27 H 30 O 6 (molar mass: 450.52 g/mol, exact mass: 450.2042 u) may refer to: | https://en.wikipedia.org/wiki/C27H30O6 |
Mometasone , also known as mometasone furoate , is a steroid (specifically, a glucocorticoid ) medication used to treat certain skin conditions , hay fever , and asthma . [ 10 ] [ 11 ] [ 12 ] Specifically it is used to prevent rather than treat asthma attacks. [ 10 ] It can be applied to the skin, inhaled, or used in t... | https://en.wikipedia.org/wiki/C27H30O6Cl2 |
Lonafarnib , sold under the brand name Zokinvy , is a medication used to reduce the risk of death due to Hutchinson-Gilford progeria syndrome and for the treatment of certain processing-deficient progeroid laminopathies in people one year of age and older. [ 3 ] [ 4 ] It is under trial for its use as combination treatm... | https://en.wikipedia.org/wiki/C27H31Br2ClN4O2 |
Chlorbenzoxamine is a drug used for functional gastrointestinal disorders .
This drug article relating to the gastrointestinal system is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H31ClN2O |
Antirrhinin is an anthocyanin . It is the 3- rutinoside of cyanidin .
It can be found in Antirrhinum majus (common snapdragon). [ 1 ] [ 2 ]
It can be found in blackcurrant , [ 3 ] açaí , [ 4 ] black raspberry , [ 5 ] litchi pericarp [ 6 ] and common fig . [ 7 ]
Cyanidin 3-O-rutinoside 5-O-glucosyltransferase uses UD... | https://en.wikipedia.org/wiki/C27H31ClO15 |
Tulipanin is an anthocyanin . It is the 3-O- rutinoside of delphinidin . It can be found in Alstroemeria spp. , Berberis spp. , Cissus sicyoides , Hymenocallis spp. , Manihot utilissima , Meliosma tenuis , Musa acuminata , Ophiopogon japonicus , Petunia exserta , Petunia reitzii , blackcurrant ( Ribes nigrum ), Schisma... | https://en.wikipedia.org/wiki/C27H31ClO16 |
Giredestrant is an investigational oral selective estrogen receptor degrader (SERD) being developed for the treatment of estrogen receptor -positive (ER+) breast cancer . [ 1 ] [ 2 ] It is a potent, nonsteroidal compound that antagonizes estrogen effects by competitively binding to both wild-type and mutant estrogen re... | https://en.wikipedia.org/wiki/C27H31F5N4O |
Budiodarone ( ATI-2042 ) is an antiarrhythmic agent and chemical analog of amiodarone that is currently being studied in clinical trials . Amiodarone is considered the most effective antiarrhythmic drug available, [ 1 ] [ 2 ] [ 3 ] but its adverse side effects, including hepatic, pulmonary and thyroid toxicity as well ... | https://en.wikipedia.org/wiki/C27H31I2NO5 |
1-Benzyl-4-[2-(diphenyl methoxy) ethyl] piperidine is a stimulant of the piperidine class which acts as a potent and selective dopamine reuptake inhibitor . [ 1 ] [ 2 ] It is closely related to vanoxerine and GBR-12,935 , which in contrast are piperazines . | https://en.wikipedia.org/wiki/C27H31NO |
The molecular formula C 27 H 31 O 15 + (molar mass: 595.53 g/mol, exact mass: 595.1663 u) may refer to: | https://en.wikipedia.org/wiki/C27H31O15 |
Triparanol ( INN Tooltip International Nonproprietary Name , BAN Tooltip British Approved Name ; brand name and development code MER/29 , as well as many other brand names) was the first synthetic cholesterol -lowering drug . [ 1 ] [ 2 ] It was patented in 1959 and introduced in the United States in 1960. [ 3 ] [ 4 ] T... | https://en.wikipedia.org/wiki/C27H32ClNO2 |
Abemaciclib , sold under the brand name Verzenio among others, is a medication for the treatment of advanced or metastatic breast cancers . It was developed by Eli Lilly and it acts as a CDK inhibitor selective for CDK4 and CDK6 . [ 4 ]
It was designated as a breakthrough therapy for breast cancer by the US Food and ... | https://en.wikipedia.org/wiki/C27H32F2N8 |
AZD-1390 is an experimental anticancer drug developed by AstraZeneca that inhibits ataxia telangiectasia mutated (ATM). [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ] [ 6 ] [ 7 ] | https://en.wikipedia.org/wiki/C27H32FN5O2 |
PD-0298029 is a drug which acts as a selective antagonist for the muscarinic acetylcholine receptor M 4 . It was developed for the treatment of Parkinson's disease , but poor bioavailability and rapid metabolism in animal studies have meant its use is largely limited to in vitro research into the M 4 and other muscarin... | https://en.wikipedia.org/wiki/C27H32N2O4 |
AZ-11713908 is a drug developed by AstraZeneca which is a peripherally selective cannabinoid agonist , acting as a potent agonist at the CB 1 receptor and a partial agonist at CB 2 . It has poor blood–brain barrier penetration, and so while it is an effective analgesic in animal tests, it produces only peripheral effec... | https://en.wikipedia.org/wiki/C27H32N4O3S2 |
BAY 60-7550 is a type 2 phosphodiesterase inhibitor . [ 1 ]
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H32N4O4 |
Adavosertib (development codes AZD1775 , MK-1775 ) is an experimental anti-cancer drug candidate. It is a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. [ 1 ] It is being developed by AstraZeneca . [ 2 ] It is being investigated as a treatment for pancreatic can... | https://en.wikipedia.org/wiki/C27H32N8O2 |
Estradiol phenylpropionate ( EPP ), also known as estradiol 17β-phenylpropionate and sold under the brand name Menformon Prolongatum , is an estrogen which is no longer marketed. [ 1 ] [ 2 ] [ 3 ] It is an estrogen ester , specifically the C17β phenylpropionate ester of estradiol . [ 1 ]
EPP has been marketed in combi... | https://en.wikipedia.org/wiki/C27H32O3 |
RS-102221 is a drug developed by Hoffmann–La Roche , which was one of the first compounds discovered that acts as a potent and selective antagonist at the serotonin 5-HT 2C receptor , with around 100× selectivity over the closely related 5-HT 2A and 5-HT 2B receptors. [ 1 ] It has anxiolytic effects in animal studies, ... | https://en.wikipedia.org/wiki/C27H33F3N4O7S |
Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines . [ 1 ] It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to the most abundant and structurally diverse class of tryptophan-proline 2,5-diketopiperazine natural produ... | https://en.wikipedia.org/wiki/C27H33N3O7 |
NESS-040C5 is a potent cannabinoid agonist which was developed for the treatment of glaucoma . [ 1 ] It has reasonable selectivity for the CB 2 receptor subtype, having a CB 2 affinity of 0.4nM, and 25x selectivity over the related CB 1 receptor. [ 2 ]
This cannabinoid related article is a stub . You can help Wikipedi... | https://en.wikipedia.org/wiki/C27H33N3OS |
In biochemistry , flavin adenine dinucleotide ( FAD ) is a redox -active coenzyme associated with various proteins , which is involved with several enzymatic reactions in metabolism . A flavoprotein is a protein that contains a flavin group , which may be in the form of FAD or flavin mononucleotide (FMN). Many flavopro... | https://en.wikipedia.org/wiki/C27H33N9O15P2 |
JWH-161 is a cannabinoid derivative that was designed by Dr John W. Huffman 's team as a hybrid between the dibenzopyran "classical" cannabinoid drugs and the novel indole derivatives, in an attempt to unravel the differences in their binding modes to the CB 1 receptor. While retaining structural elements from both fam... | https://en.wikipedia.org/wiki/C27H33NO2 |
Ethamoxytriphetol (developmental code name MER-25 ) is a synthetic nonsteroidal antiestrogen that was studied clinically in the late 1950s and early 1960s but was never marketed. [ 1 ] MER-25 was first reported in 1958, and was the first antiestrogen to be discovered. [ 2 ] [ 3 ] [ 4 ] It has been described as "essenti... | https://en.wikipedia.org/wiki/C27H33NO3 |
Tris(2,4,6-trimethoxyphenyl)phosphine ( TTMPP ) is a large tri aryl organophosphine whose strong Lewis-basic properties make it useful as an organocatalyst for several types of chemical reactions .
TTMPP removes the trimethylsilyl group from ketene silyl acetals (the enol ether of esters ) to give enolates that can th... | https://en.wikipedia.org/wiki/C27H33O9P |
Propidium iodide (or PI ) is a fluorescent intercalating agent that can be used to stain cells and nucleic acids . PI binds to DNA by intercalating between the bases with little or no sequence preference. When in an aqueous solution, PI has a fluorescent excitation maximum of 493 nm (blue-green), and an emission maximu... | https://en.wikipedia.org/wiki/C27H34I2N4 |
Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) [ 1 ] used for the treatment of hypertension and congestive heart failure . Moexipril can be administered alone or with other antihypertensives or diuretics . [ 2 ]
It works by inhibiting the conversion of angiotensin I to angiotensin II . [ 3 ]
... | https://en.wikipedia.org/wiki/C27H34N2O7 |
Strictosidine is a natural chemical compound and is classified as a glucoalkaloid and a vinca alkaloid . It is formed by the Pictet–Spengler condensation reaction of tryptamine with secologanin , catalyzed by the enzyme strictosidine synthase . Thousands of strictosidine derivatives are sometimes referred to by the br... | https://en.wikipedia.org/wiki/C27H34N2O9 |
Piritramide [ 3 ] ( R-3365 , trade names Dipidolor , Piridolan , Pirium and others) is a synthetic opioid analgesic (narcotic painkiller) that is marketed in certain European countries including: Austria , Belgium , Czech Republic , Slovenia , Germany and the Netherlands . [ 4 ] It comes in free form, is about 0.75x ti... | https://en.wikipedia.org/wiki/C27H34N4O |
Retosiban also known as GSK-221,149-A [ 1 ] [ 2 ] is an oral drug which acts as an oxytocin receptor antagonist . It is being developed by GlaxoSmithKline for the treatment of preterm labour . [ 3 ] [ 4 ] Retosiban has high affinity for the oxytocin receptor (K i = 0.65 nM) and has greater than 1400-fold selectivity [... | https://en.wikipedia.org/wiki/C27H34N4O5 |
Cytochrophin-4 is an opioid peptide . [ 1 ]
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H34N4O7 |
L-765,314 is a drug which acts as a potent and selective antagonist of the α 1 -adrenergic receptor subtype α 1B . [ 1 ] It has mainly been used to investigate the role of α 1B -adrenergic receptors in the regulation of blood pressure. [ 2 ] [ 3 ] The α 1B receptor is also thought to have an important role in the brain... | https://en.wikipedia.org/wiki/C27H34N6O5 |
Naringin dihydrochalcone , sometimes abbreviated to naringin DC , is an artificial sweetener derived from naringin , a bitter compound found in citrus . [ 1 ]
Naringin dihydrochalcone is a phloretin glycoside discovered at the same time as neohesperidin dihydrochalcone during the 1960s as part of a United States Depa... | https://en.wikipedia.org/wiki/C27H34O14 |
1D-LSD ( 1-(1,2-dimethylcyclobutane-1-carbonyl)-lysergic acid diethylamide , SYN-L-229 ) is a psychotropic substance and a research chemical that has potential psychedelic effects. It is believed to be a prodrug for LSD and has replaced 1V-LSD in Germany after 1V-LSD became covered by the German NpSG law in 2022. [ 1 ]... | https://en.wikipedia.org/wiki/C27H35N3O2 |
Met-enkephalin , also known as metenkefalin ( INN ), sometimes referred to as opioid growth factor ( OGF ), [ 1 ] is a naturally occurring , endogenous opioid peptide that has opioid effects of a relatively short duration. It is one of the two forms of enkephalin , the other being leu-enkephalin . The enkephalins are c... | https://en.wikipedia.org/wiki/C27H35N5O7S |
Acetorphine is a potent opioid analgesic , up to 8700 times stronger than morphine by weight. [ 1 ] It is a derivative of the more well-known opioid etorphine , which is used as a very potent veterinary painkiller and anesthetic medication, primarily for the sedation of large animals such as elephants, giraffes and rhi... | https://en.wikipedia.org/wiki/C27H35NO5 |
Tetramethylcyclopropylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug . [ 2 ]
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching , nausea and potentially serious respiratory depression , which can be life-threatening. Fenta... | https://en.wikipedia.org/wiki/C27H36N2O |
Altoqualine is an isoquinoline once studied for its potential use as an antihistamine and antiallergic , [ 1 ] [ 2 ] [ 3 ] but it was never a marketed drug. It is an inhibitor of histidine decarboxylase . [ 2 ] It was only tested in men, not women. [ 3 ]
This drug article relating to the respiratory system is a stub ... | https://en.wikipedia.org/wiki/C27H36N2O8 |
AR-A000002 , also known as AZD-8129 , is a drug which is one of the first compounds developed to act as a selective antagonist for the serotonin receptor 5-HT 1B , [ 1 ] with approximately 10x selectivity for 5-HT 1B over the closely related 5-HT 1D receptor . [ 2 ] [ 3 ] It has been shown to produce sustained increase... | https://en.wikipedia.org/wiki/C27H36N4O2 |
ST-148 is a drug which acts as a subtype selective antagonist for dopamine receptors , with reasonable selectivity for the D2L subtype. [ 1 ] | https://en.wikipedia.org/wiki/C27H36N4O3S |
Ibutamoren ( INN Tooltip International Nonproprietary Name ; developmental code MK-677 , MK-0677 , LUM-201 , L-163,191 ; former tentative brand name Oratrope ) is a potent , long-acting, orally-active , selective , and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue , mimicking the growth ... | https://en.wikipedia.org/wiki/C27H36N4O5S |
Fedratinib , sold under the brand name Inrebic , is an anti-cancer medication used to treat myeloproliferative diseases including myelofibrosis . [ 6 ] It is used in the form of fedratinib hydrochloride capsules that are taken by mouth. It is a semi-selective inhibitor of Janus kinase 2 (JAK-2). [ 6 ] [ 7 ] It was appr... | https://en.wikipedia.org/wiki/C27H36N6O3S |
Prednicarbate is a relatively new topical corticosteroid drug. It is similar in potency to hydrocortisone . Corticosteroids have always been an important part of the pharmacological arsenal of dermatology ; however, their tendency to produce side-effects has caused the need to search for new preparations. [ 1 ]
It is ... | https://en.wikipedia.org/wiki/C27H36O8 |
Chlormadinone caproate ( CMC ) is a progestin and a progestogen ester which was studied for potential use in combined injectable contraceptives but was never marketed. [ 1 ] [ 2 ] [ 3 ] [ 4 ] It was assessed in combination with estradiol valerate at doses of 80 mg and 3 mg, respectively. [ 1 ] [ 2 ] [ 3 ] In addition t... | https://en.wikipedia.org/wiki/C27H37ClO4 |
Betamethasone valerate is a synthetic glucocorticoid ester . It is the 17-valerate ester of betamethasone . [ 1 ] [ 2 ] Betamethasone valerate is often used to treat mild eczema with good efficacy and lower incidence of steroid induced adverse effects due to its lower potency compared to other glucocorticoids. [ 3 ] Be... | https://en.wikipedia.org/wiki/C27H37FO6 |
(+)-BW373U86 is an opioid analgesic drug used in scientific research. [ 1 ] [ 2 ]
BW373U86 is a selective agonist for the δ-opioid receptor , with approximately 15× stronger affinity for the δ-opioid than the μ-opioid receptor . [ 3 ] It has potent analgesic and antidepressant effects in animal studies. [ 4 ] [ 5 ] In... | https://en.wikipedia.org/wiki/C27H37N3O2 |
Darunavir ( DRV ), sold under the brand name Prezista among others, is an antiretroviral medication used to treat and prevent HIV/AIDS . [ 1 ] It is generally recommended for use with other antiretrovirals. [ 1 ] [ 4 ] It is often used with low doses of ritonavir or cobicistat to increase darunavir levels. [ 1 ] It may... | https://en.wikipedia.org/wiki/C27H37N3O7S |
LP-44 is a drug which acts as a potent and selective agonist at the 5HT 7 serotonin receptor . While LP-44 is less selective than the related compound LP-12 , it has been more widely used in research and has been used to show the complex role of 5-HT 7 receptors in several aspects of brain function, including regulatio... | https://en.wikipedia.org/wiki/C27H37N3OS |
Falecalcitriol ( INN ) is an analog of calcitriol . It has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo. [ 1 ]
This drug article relating to the gastrointestinal system is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H38F6O3 |
Verapamil , sold under various trade names, [ 1 ] is a calcium channel blocker medication used for the treatment of high blood pressure , angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia . [ 9 ] It may also be used for the prevention of migraines and cluster headaches . [ 10... | https://en.wikipedia.org/wiki/C27H38N2O4 |
AFDX-384 ( BIBN-161 ) is a drug which acts as a selective antagonist of the muscarinic acetylcholine receptors , with selectivity for the M 2 and M 4 subtypes. It is used mainly for mapping the distribution of M 2 and M 4 muscarinic receptors in the brain, and studying their involvement in the development and treatment... | https://en.wikipedia.org/wiki/C27H38N6O2 |
Norethisterone enanthate ( NETE ), also known as norethindrone enanthate , is a form of hormonal birth control which is used to prevent pregnancy in women. [ 1 ] [ 2 ] [ 3 ] It is used both as a form of progestogen-only injectable birth control and in combined injectable birth control formulations. It may be used follo... | https://en.wikipedia.org/wiki/C27H38O3 |
Prednisolone tebutate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester . [ 1 ]
This article about a steroid is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H38O6 |
Jervine is a steroidal alkaloid with molecular formula C 27 H 39 NO 3 which is derived from the plant genus Veratrum . Similar to cyclopamine , which also occurs in the genus Veratrum , it is a teratogen implicated in birth defects when consumed by animals during a certain period of their gestation . [ citation needed ... | https://en.wikipedia.org/wiki/C27H39NO3 |
Prednisolamate , also known as prednisolone 21-diethylaminoacetate , is a synthetic corticosteroid . [ 1 ] [ 2 ] It is or was a component of Etaproctene , which contains lidocaine , prednisolamate hydrochloride, and tetryzoline . [ 3 ]
This article about a steroid is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H39NO6 |
Cilengitide (EMD 121974) is a molecule designed and synthesized at the Technical University Munich in collaboration with Merck KGaA in Darmstadt . It is based on the cyclic peptide cyclo(-RGDfV-) , which is selective for α v integrins , which are important in angiogenesis (forming new blood vessels), and other aspects ... | https://en.wikipedia.org/wiki/C27H40N8O7 |
AMG-36 (part of the AM cannabinoid series ) is an analgesic drug which is a cannabinoid agonist . It is a derivative of Δ 8 - THC substituted with a cyclopentane group on the 3-position side chain. AMG-36 is a potent agonist at both CB 1 and CB 2 with moderate selectivity for CB 1 , with a K i of 0.45 nM at CB 1 vs 1.... | https://en.wikipedia.org/wiki/C27H40O2 |
The molecular formula C 27 H 40 O 4 (molar mass: 428.60 g/mol, exact mass: 428.2927 u) may refer to: | https://en.wikipedia.org/wiki/C27H40O4 |
Fusaproliferin is a mycotoxin that is naturally produced by the fungi genus Fusarium to protect itself against competing microorganisms . It was first isolated from the Fusarium proliferatum species but can be found in at least 15 species within this genus. [ 1 ] It was initially named proliferin, but the name was late... | https://en.wikipedia.org/wiki/C27H40O5 |
Nirogacestat , sold under the brand name Ogsiveo , is an anti-cancer medication used for the treatment of desmoid tumors . [ 1 ] [ 2 ] [ 3 ] It is a selective gamma secretase inhibitor [ 4 ] that is taken by mouth . [ 1 ]
The most common side effects include diarrhea , ovarian toxicity, rash, nausea, fatigue, stomatit... | https://en.wikipedia.org/wiki/C27H41F2N5O |
Cyclopamine (11-deoxojervine) is a naturally occurring steroidal alkaloid . It is a teratogenic component of corn lily ( Veratrum californicum ), which when consumed during gestation has been demonstrated to induce birth defects, including the development of a single eye ( cyclopia ) in offspring. [ 1 ] The molecule wa... | https://en.wikipedia.org/wiki/C27H41NO2 |
16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl]
7-17-13-18(29)9-11-25(17,3)24(19)21(30)14-26(20,27)4/h13,19-21,24,30,
Hydrocortamate (brand names Magnacort , Ulcortis ) is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. [ 1 ] [ 2 ] It is used topically to treat inflamma... | https://en.wikipedia.org/wiki/C27H41NO6 |
Latanoprostene bunod , sold under the brand name Vyzulta , is an ophthalmic medication used for the reduction of intraocular pressure in people with open-angle glaucoma or ocular hypertension . [ 2 ] [ 3 ] It is a prostaglandin analog [ 2 ] which, when broken down by esterases and other metabolism, produces latanoprost... | https://en.wikipedia.org/wiki/C27H41NO8 |
Benzethonium chloride , also known as hyamine is a synthetic quaternary ammonium salt . This compound is an odorless white solid, soluble in water. It has surfactant , antiseptic , and anti-infective properties and it is used as a topical antimicrobial agent in first aid antiseptics. It is also found in cosmetics and ... | https://en.wikipedia.org/wiki/C27H42ClNO2 |
Ixabepilone ( INN ; also known as azaepothilone B , codenamed BMS-247550 ) is a pharmaceutical drug developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer. [ 1 ]
Ixabepilone is a semi-synthetic analog of epothilone B, a natural chemical compound produced by Sorangium cellulosum . [ 2 ] The struc... | https://en.wikipedia.org/wiki/C27H42N2O5S |
7-Dehydrodesmosterol (or cholesta-5,7,24-trien-3-beta-ol ) is a cholesterol intermediate. [ 1 ]
This article about a steroid is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H42O |
AM-4030 is an analgesic drug which is a cannabinoid receptor agonist . It is a derivative of HU-210 which has been substituted with a 6β-((E)-3-hydroxyprop-1-enyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-4030 represents... | https://en.wikipedia.org/wiki/C27H42O4 |
5α-Hydroxylaxogenin is a chemical compound which is a semi-synthetic derivative of laxogenin. It is not found in the Chinese medicinal plant Smilax sieboldii , instead, identification of several synthetic impurities by Dr. Chittiboyina's group suggested that it is synthesized from diosgenin . [ 1 ] [ 2 ] It acts as a p... | https://en.wikipedia.org/wiki/C27H42O5 |
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