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Solanidine is a poisonous steroidal alkaloid chemical compound that occurs in plants of the family Solanaceae , such as potato and Solanum americanum . [ 2 ] [ 3 ] The sugar portion of glycoalkaloids hydrolyses in the body, leaving the solanidine portion. [ 4 ]
Solanidine is the hydrolyzed form [ 4 ] of several natura... | https://en.wikipedia.org/wiki/C27H43NO |
Solasodine is a poisonous alkaloid chemical compound that occurs in plants of the family Solanaceae such as potatoes and tomatoes. [ 1 ] Solasonine and solamargine are glycoalkaloid derivatives of solasodine. [ 1 ] Solasodine is teratogenic to hamster fetuses in a dose of 1200 to 1600 mg/kg. [ 2 ] A 2013 literature sur... | https://en.wikipedia.org/wiki/C27H43NO2 |
Onternabez (also known as HU-308 , HU308 , PPP-003 , and ARDS-003 ) is a synthetic cannabinoid that acts as a potent cannabinoid agonist . It is highly selective for the cannabinoid-2 receptor (CB 2 receptor) subtype, with a selectivity more than 5,000 times greater for the CB 2 receptor than the CB 1 receptor . [ 1 ] ... | https://en.wikipedia.org/wiki/C27H43O3 |
Antipain is an oligopeptide that is isolated from actinomycetes and used in biochemical research as a protease inhibitor of trypsin and papain . [ 1 ] It was discovered in 1972 and was the first natural peptide found that contained an ureylene group. [ 2 ] Antipain can aid in prevention of coagulation in blood. It is a... | https://en.wikipedia.org/wiki/C27H44N10O6 |
AM-919 (part of the AM cannabinoid series ) is an analgesic drug which is a cannabinoid receptor agonist . It is a derivative of HU-210 which has been substituted with a 6β-(3-hydroxypropyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs... | https://en.wikipedia.org/wiki/C27H44O4 |
Ecdysone is a [ clarification needed ] prohormone of the major insect molting hormone 20-hydroxyecdysone , secreted from the prothoracic glands . It is of steroidal structure. Insect molting hormones (ecdysone and its homologues) are generally called ecdysteroids . Ecdysteroids act as moulting hormones of arthropods bu... | https://en.wikipedia.org/wiki/C27H44O6 |
20-Hydroxyecdysone ( ecdysterone or 20E ) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods . It is therefore one of the most common moulting hormones in insects, crabs, etc. A phytoecdysteroid produced by various plants, including Cyanotis vaga , Ajuga t... | https://en.wikipedia.org/wiki/C27H44O7 |
Cholesteryl chloride , also called 3-chlorocholest-5-ene or 3β-chlorocholest-5-ene , is an organic chemical , an organochloride derivate cholesterol . It is a liquid crystal material forming clockwise cholesteric liquid crystals . It is a transparent liquid, or a soft crystalline material with melting point around 94-9... | https://en.wikipedia.org/wiki/C27H45Cl |
Turosteride ( FCE-26,073 ) is a selective inhibitor of the enzyme 5α-reductase which was under investigation by GlaxoSmithKline for the treatment of benign prostatic hyperplasia (BPH), but was never marketed. [ 1 ] [ 2 ] [ 3 ] Similarly to finasteride , turosteride is selective for the type II isoform of 5α-redcutase, ... | https://en.wikipedia.org/wiki/C27H45N3O3 |
Fosgonimeton is an investigational new drug that is being evaluated to treat neurodegenerative diseases such as Alzheimer's and Parkinson's disease . [ 1 ] It is a pro-drug of the active metabolite dihexa . Dihexa in turn binds to the hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met . ... | https://en.wikipedia.org/wiki/C27H45N4O8P |
Boceprevir ( INN , trade name Victrelis ) is a protease inhibitor used to treat hepatitis caused by hepatitis C virus (HCV) genotype 1. [ 2 ] [ 3 ] It binds to the HCV nonstructural protein 3 active site. [ 4 ]
It was initially developed by Schering-Plough , [ 5 ] then by Merck after it acquired Schering in 2009. It w... | https://en.wikipedia.org/wiki/C27H45N5O5 |
Olesoxime ( TRO19622 ) is an experimental drug formerly under development by the now-defunct French company Trophos as a treatment for a range of neuromuscular disorders . It has a cholesterol -like structure and belongs to the cholesterol - oxime family of mitochondrial pore modulators . [ 1 ] [ 2 ]
In preclinical st... | https://en.wikipedia.org/wiki/C27H45NO |
Cholestenes are chiral molecules that are derivatives of cholestanes that have a double bond . If there are two double bonds, the molecule is known as a "cholestadiene". [ 1 ] Examples include fusidic acid , lanosterol , and stigmasterol . Cholestene is a widely available chemical, used and sold commercially with red y... | https://en.wikipedia.org/wiki/C27H46 |
20α,22 R -Dihydroxycholesterol , or (3β)-cholest-5-ene-3,20,22-triol is an endogenous , metabolic intermediate in the biosynthesis of the steroid hormones from cholesterol . [ 1 ] [ 2 ] Cholesterol ((3β)-cholest-5-en-3-ol) is hydroxylated by cholesterol side-chain cleavage enzyme (P450scc) to form 22 R -hydroxycholeste... | https://en.wikipedia.org/wiki/C27H46O3 |
Cholesterol sulfate , or cholest-5-en-3β-ol sulfate , is an endogenous steroid and the C3β sulfate ester of cholesterol . [ 1 ] [ 2 ] It is formed from cholesterol by steroid sulfotransferases (SSTs) such as SULT2B1b (also known as cholesterol sulfotransferase) [ 2 ] and is converted back into cholesterol by steroid su... | https://en.wikipedia.org/wiki/C27H46O4S |
Joro spider toxin (joro toxin, JSTX) – a toxin which was originally extracted from the venom of the joro spider ( Trichonephila clavata ), originally native to Japan.
Joro toxin has demonstrated the ability to selectively block
It inhibits
Joro toxin does not affect | https://en.wikipedia.org/wiki/C27H47N7O6 |
5β-Coprostanol ( 5β-cholestan-3β-ol ) is a 27- carbon stanol formed from the net reductive metabolism of cholesterol (cholest-5en-3β-ol) in the gut of most higher animals and birds. This compound has frequently been used as a biomarker for the presence of human faecal matter in the environment . 5β-coprostanol is thoug... | https://en.wikipedia.org/wiki/C27H48O |
Scymnol , more specifically 5β-scymnol , is a synthetic INCI -listed skin conditioning ingredient. [ 1 ] [ 2 ] [ 3 ] The molecule is a steroid derivative that behaves as a hydroxyl radical scavenger and is used for the treatment of skin blemishes such as blocked pores and acne . [ 4 ] [ 5 ]
The molecule was identified... | https://en.wikipedia.org/wiki/C27H48O6 |
Axona was previously marketed as a medical food for the clinical dietary management of the impairment of metabolic processes associated with mild to moderate Alzheimer's disease . It is a proprietary formulation of fractionated palm kernel oil ( caprylic triglyceride ), a medium-chain triglyceride . Cericin, [ 1 ] th... | https://en.wikipedia.org/wiki/C27H50O6 |
Brincidofovir , sold under the brand name Tembexa , is an antiviral drug used to treat smallpox . Brincidofovir is a prodrug of cidofovir . [ 3 ] Conjugated to a lipid , the compound is designed to release cidofovir intracellularly , allowing for higher intracellular and lower plasma concentrations of cidofovir, effect... | https://en.wikipedia.org/wiki/C27H52N3O7P |
Trioctylmethylammonium bis(trifluoromethylsulfonyl)imide is an ionic liquid [ 3 ] that is produced by Solvent Innovation, now part of EMD Chemicals .
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H54F6N2O4S2 |
Carboceric acid , or heptacosanoic acid or heptacosylic acid , is a 27- carbon long-chain saturated fatty acid with the chemical formula CH 3 (CH 2 ) 25 COOH . [ 1 ] Its name derives from a combination of the word " Carbon " and κηρός (Keros), meaning beeswax or honeycomb in Ancient Greek , since the acid can be found ... | https://en.wikipedia.org/wiki/C27H54O2 |
1-Heptacosanol is a fatty alcohol . [ 1 ]
This article about an alcohol is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C27H56O |
Blisibimod (also known as A-623 , formerly AMG 623 ) is a selective antagonist of B-cell activating factor (BAFF, also known as B-lymphocyte stimulator or BLyS), being developed by Anthera Pharmaceuticals as a treatment for systemic lupus erythematosus . [ 1 ] It is currently under active investigation in clinical tria... | https://en.wikipedia.org/wiki/C2836H4376N756O858S26 |
The drug aprotinin (Trasylol, previously Bayer and now Nordic Group pharmaceuticals), is a small protein bovine pancreatic trypsin inhibitor ( BPTI ), or basic trypsin inhibitor of bovine pancreas , which is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes . Under the trade name Trasy... | https://en.wikipedia.org/wiki/C284H432N84O79S7 |
Lepirudin is an anticoagulant that functions as a direct thrombin inhibitor .
Brand name: Refludan , Generic: Lepirudin rDNA for injection.
Lepirudin is a recombinant hirudin [ 1 ] derived from yeast cells. Lepirudin is almost identical to hirudin extracted from Hirudo medicinalis , having the amino acid sequence L... | https://en.wikipedia.org/wiki/C288H448N80O110S6 |
Gallagic acid is a polyphenolic chemical compound that can be found in the ellagitannins, a type of tannin, found in Punica granatum (pomegranate). [ 1 ] It is a building block of the corresponding tannin punicalagin , punicalin , punicacortein C and 2-O-galloyl-punicalin .
This article about an aromatic compound is a... | https://en.wikipedia.org/wiki/C28H14O18 |
Brilliant Black BN (also known as Brilliant Black PN , Brilliant Black A , Black PN , Food Black 1 , Naphthol Black , C.I. Food Black 1 , or C.I. 28440 ) is a synthetic black diazo dye . It is soluble in water. It usually comes as tetrasodium salt . It has the appearance of solid, fine powder or granules. Calcium and p... | https://en.wikipedia.org/wiki/C28H17N5Na4O14S4 |
α-Naphtholphthalein (C 28 H 18 O 4 ) is a phthalein dye used as a pH indicator with a visual transition from colorless/reddish to greenish blue at pH 7.3–8.7.
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H18O4 |
Cinchotannic acid is a tannin contained in many cinchona barks, which by oxidation rapidly yields a dark-coloured phlobaphene [ 1 ] called red cinchonic , [ 2 ] cinchono-fulvic acid or cinchona red . [ 3 ]
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H19O17 |
Lamellarins are a group of pyrrole alkaloids first isolated in 1985 from the marine mollusk Lamellaria in the waters of Palau . Over 70 lamellarins and similar compounds were subsequently isolated. Other similar compounds include ningalins, lukianols, polycitones, and storniamides. [ 1 ]
These compounds have shown a w... | https://en.wikipedia.org/wiki/C28H21NO8 |
Flumethrin is a pyrethroid insecticide . [ 1 ] It is used externally in veterinary medicine against parasitic insects and ticks on cattle, sheep, goats, horses, and dogs, [ 2 ] and the treatment of parasitic mites in honeybee colonies.
Flumethrin is a complex mixture of stereoisomers . The molecule contains three asym... | https://en.wikipedia.org/wiki/C28H22Cl2FNO3 |
Tannic acid is a specific form of tannin , a type of polyphenol . Its weak acidity ( pK a around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C 76 H 52 O 46 , which corresponds with decagalloyl glucose, but in fact it is a mixture of polygal... | https://en.wikipedia.org/wiki/C28H22O11 |
Cavicularin is a natural phenolic secondary metabolite isolated from the liverwort Cavicularia densa . This macrocycle is unusual because it was the first compound isolated from nature displaying optical activity solely due to the presence of planar chirality and axial chirality . The specific rotation for (+)-cavicula... | https://en.wikipedia.org/wiki/C28H22O4 |
Ampelopsin A is a resveratrol dimer found in Ampelopsis glandulosa var. hancei (formerly A. brevipedunculata var. hancei ). [ 1 ] [ 2 ] [ 3 ]
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H22O7 |
Cabozantinib , sold under the brand names Cometriq and Cabometyx among others, is an anti-cancer medication used to treat medullary thyroid cancer , renal cell carcinoma , and hepatocellular carcinoma . [ 9 ] [ 10 ] It is a small-molecule tyrosine-kinase inhibitor (TKI) of c-Met (HGFR) and VEGFR2 , and also inhibits AX... | https://en.wikipedia.org/wiki/C28H24FN3O5 |
EG-2201 (also known as NA-5F-PCZMO using EUDA systematic nomenclature [ 1 ] ) is a synthetic cannabinoid belonging to the indole-3-carboxamide family. [ 2 ] It has been identified as a designer drug and is structurally related to other synthetic cannabinoids, such as EG-018 and MDMB-CHMCZCA . It is primarily used illic... | https://en.wikipedia.org/wiki/C28H24FNO |
Tannic acid is a specific form of tannin , a type of polyphenol . Its weak acidity ( pK a around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C 76 H 52 O 46 , which corresponds with decagalloyl glucose, but in fact it is a mixture of polygal... | https://en.wikipedia.org/wiki/C28H24O11 |
Tannic acid is a specific form of tannin , a type of polyphenol . Its weak acidity ( pK a around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C 76 H 52 O 46 , which corresponds with decagalloyl glucose, but in fact it is a mixture of polygal... | https://en.wikipedia.org/wiki/C28H24O12 |
Balanophotannin D is a hydrolyzable tannin found in Balanophora japonica . It contains an oxidized hexahydroxydiphenoyl (HHDP) group . [ 1 ]
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H24O16 |
3,4,5-Tri- O -galloylquinic acid is a hydrolysable tannin found in Lepidobotrys staudtii , [ 1 ] in Guiera senegalensis [ 2 ] or in the resurrection plant ( Myrothamnus flabellifolius ). [ 3 ]
It is classified as a natural product with anti-HIV activity [ 1 ] and a DNA polymerase inhibitor . [ 4 ]
This article about ... | https://en.wikipedia.org/wiki/C28H24O18 |
Riccardin C is a macrocyclic bis(bibenzyl) . It is a secondary metabolite isolated from the Siberian cowslip subspecies Primula veris subsp. macrocalyx , [ 2 ] [ 3 ] in Reboulia hemisphaerica [ 4 ] and in the Chinese liverwort Plagiochasma intermedium . [ 5 ]
In 2005, the compound was prepared by total synthesis toget... | https://en.wikipedia.org/wiki/C28H24O4 |
Amurensin A is an oligostilbene isolated from the roots of Vitis amurensis . [ 1 ] It is a partially oxidized resveratrol dimer with a C8-C8' connection. [ 2 ]
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H24O7 |
1- O -Acetyl-2,3,5-tri- O -benzoyl-β- D -ribofuranose , also called β- D -ribofuranose 1-acetate 2,3,5-tribenzoate , is a ribose -derived compound used in nucleoside synthesis . [ 1 ]
In the patented formation of 1- O -acetyl-2,3,5-tri- O -benzoyl-β- L -ribofuranose, a reactor containing thionyl chloride (5 ml) and me... | https://en.wikipedia.org/wiki/C28H24O9 |
Basic Black 2 is a dye of the azine class that is soluble in water. The dye is mostly made to obtain black and green. In water, dark green and light blue might be viewed. In ethanol , red light blue can be observed. [ 1 ]
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H26ClN5O |
Isometamidium chloride is a triazene trypanocidal agent used in veterinary medicine. [ 1 ] [ 2 ]
It consists of a single ethidium bromide like subunit linked to a fragment of the diminazene molecule. [ citation needed ]
The Gibe River Valley in southwest Ethiopia showed universal resistance between July 1989 and Febr... | https://en.wikipedia.org/wiki/C28H26ClN7 |
Balanol is a fungal metabolite produced by the fungus Verticillium balanoides . [ 1 ] It is a potent inhibitor of the serine/threonine kinases protein kinase A (PKA) and protein kinase C (PKC), binding in a similar manner with that of ATP . [ 2 ] Balanol was discovered in 1993 in the search for novel inhibitors of PKC,... | https://en.wikipedia.org/wiki/C28H26N2O10 |
Staurosporine (antibiotic AM-2282 or STS) is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus . [ 1 ] It was the first of over 50 alkaloids that were discovered to share this type of bis-indole chemical structure. The chemical structure of staurosporine was elucidated by X-ray... | https://en.wikipedia.org/wiki/C28H26N4O3 |
Cefpimizole ( INN ) is a third-generation cephalosporin antibiotic .
This stereochemistry article is a stub . You can help Wikipedia by expanding it .
This systemic antibiotic -related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H26N6O10S2 |
Tannic acid is a specific form of tannin , a type of polyphenol . Its weak acidity ( pK a around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C 76 H 52 O 46 , which corresponds with decagalloyl glucose, but in fact it is a mixture of polygal... | https://en.wikipedia.org/wiki/C28H26O15 |
Taxillusin is a flavonol found in the parasitic plant Taxillus kaempferi . [ 1 ] [ 2 ] It is a galloylated 3- O - glucoside of quercetin .
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H26O16 |
Relcovaptan ( SR-49059 ) is a non- peptide vasopressin receptor antagonist , selective for the V1a subtype. [ 1 ] It has shown positive initial results for the treatment of Raynaud's disease and dysmenorrhoea , and as a tocolytic , [ 2 ] although it is not yet approved for clinical use.
This hormonal preparation artic... | https://en.wikipedia.org/wiki/C28H27Cl2N3O7S |
Penfluridol ( Semap , Micefal , Longoperidol ) is a highly potent, first generation diphenylbutylpiperidine antipsychotic . [ 2 ] It was discovered at Janssen Pharmaceutica in 1968. [ 3 ] Related to other diphenylbutylpiperidine antipsychotics, pimozide and fluspirilene , penfluridol has an extremely long elimination h... | https://en.wikipedia.org/wiki/C28H27ClF5NO |
Olorofim ( F901318 ) is an experimental antifungal drug being developed for invasive mold infections. [ 1 ] [ 2 ] If approved it would be a first-in-class medication (for the orotomide class). In 2023, the FDA decided not to approve the drug and to request more data about the safety of the drug. [ 3 ] Olorofim does not... | https://en.wikipedia.org/wiki/C28H27FN6O2 |
Netarsudil , sold under the brand name Rhopressa among others, is a medication for the treatment of glaucoma . [ 1 ] [ 2 ] [ 3 ] In the United States, in December 2017, the Food and Drug Administration (FDA) approved a 0.02% ophthalmic solution for the lowering of elevated intraocular pressure in people with open-angle... | https://en.wikipedia.org/wiki/C28H27N3O3 |
Clopimozide ( R-29,764 ) is a typical antipsychotic drug of the diphenylbutylpiperidine class. [ 1 ] [ 2 ] It is very potent and has an extremely long duration of action, lasting at least one week with a single dose. [ 3 ] [ 4 ] [ 5 ] It was developed by Janssen Pharmaceutica but was never marketed.
This drug article ... | https://en.wikipedia.org/wiki/C28H28ClF2N3O |
Difenoxin ( Motofen , R-15403 ) is an opioid drug used, often in combination with atropine , to treat diarrhea. [ 2 ] It is the principal metabolite of diphenoxylate . [ 3 ] [ 4 ] : 558
It was first approved in the US in 1978 [ 5 ] and in 1980 in the former West Germany. [ 6 ] : 485
Difenoxin crosses the blood brain... | https://en.wikipedia.org/wiki/C28H28N2O2 |
Naltalimide ( INN ; development code TRK-130 , formerly TAK 363 ) is a novel, centrally -acting opioid drug which is under development by Takeda and Toray for the treatment of overactive bladder / urinary incontinence . [ 1 ] [ 2 ] It acts as a potent and selective partial agonist of the μ-opioid receptor (K i = 0.268 ... | https://en.wikipedia.org/wiki/C28H28N2O5 |
Ruboxistaurin (proposed brand name Arxxant ) is an investigational drug for diabetic retinopathy being investigated by Eli Lilly and Company . It is a member of the bisindolylmaleimide family.
In February 2006, Lilly submitted a New Drug Application for ruboxistaurin, and on August 18, 2006, Lilly received an approva... | https://en.wikipedia.org/wiki/C28H28N4O3 |
Tannic acid is a specific form of tannin , a type of polyphenol . Its weak acidity ( pK a around 6) is due to the numerous phenol groups in the structure. The chemical formula for commercial tannic acid is often given as C 76 H 52 O 46 , which corresponds with decagalloyl glucose, but in fact it is a mixture of polygal... | https://en.wikipedia.org/wiki/C28H28O14 |
19-Nor-5-androstenediol , also known as estr-5-ene-3β,17β-diol , is a synthetic , orally active anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone (nandrolone) that was never introduced for medical use . [ 1 ] [ 2 ] [ 3 ] It is an androgen prohormone of nandrolone and of other 19-norandrostanes . ... | https://en.wikipedia.org/wiki/C28H28O2 |
DIPAMP is an organophosphorus compound that is used as a ligand in homogeneous catalysis . It is a white solid that dissolves in organic solvents. Work on this compound by W. S. Knowles was recognized with the Nobel Prize in Chemistry . [ 1 ] DIPAMP was the basis for one of the first industrial scale asymmetric hydro... | https://en.wikipedia.org/wiki/C28H28O2P2 |
Adapalene , sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne , and is also used off-label to treat keratosis pilaris as well as other skin conditions. [ 6 ] Studies have found adapalene is as effective as other retinoids, while... | https://en.wikipedia.org/wiki/C28H28O3 |
Israpafant ( Y-24180 ) is a drug which acts as a selective antagonist for the platelet-activating factor receptor , [ 1 ] and was originally developed for the treatment of asthma . [ 2 ] Its chemical structure is a thienotriazolodiazepine , closely related to the sedative benzodiazepine derivative etizolam . However i... | https://en.wikipedia.org/wiki/C28H29ClN4S |
Bephenium hydroxynaphthoate ( INN , trade names Alcopara , Alcopar , Befenium , Debefenium , Francin , Nemex ) is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis . [ 1 ] [ 2 ] It is formulated as a salt between the active pharmaceutical ingredient , bephenium, and 3-hydroxy-2-... | https://en.wikipedia.org/wiki/C28H29NO4 |
Arzoxifene ( INN Tooltip International Nonproprietary Name ; developmental code name LY-353381 ) is a selective estrogen receptor modulator (SERM) of the benzothiophene group which was never marketed. [ 1 ] It is a potent estrogen antagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain ... | https://en.wikipedia.org/wiki/C28H29NO4S |
AMN082 ( N , N ′ -dibenzhydrylethane-1,2-diamine ) is a selective metabotropic glutamate receptor 7 (mGluR7) allosteric agonist . [ 1 ] [ 2 ] It mimics the effect of glutamate . AMN082 is the first selective mGluR7 agonist and has expanded the potential array of research opportunities on the effects of mGluR7 in the ce... | https://en.wikipedia.org/wiki/C28H30Cl2N2 |
Potrasertib is an investigational new drug that is being evaluated by IMPACT Therapeutics for the treatment of advanced solid tumors. It is oral inhibitor of WEE1 kinase, a key regulator of cell cycle checkpoints . [ 1 ] [ 2 ]
This pharmacology -related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H30Cl2N8O |
FGI-104 is the name of an experimental broad-spectrum antiviral drug , with activity against a range of viruses including hepatitis B , hepatitis C , HIV , Ebola virus , and Venezuelan equine encephalitis virus . [ 1 ]
The drug acts by inhibiting the protein TSG101 , which transports newly manufactured virions to the ... | https://en.wikipedia.org/wiki/C28H30ClN3O3 |
Ocedurenone , formerly known as KBP-5074 , [ 1 ] is a nonsteroidal, selective mineralocorticoid receptor antagonist that is being developed to treat hypertension in patients with chronic kidney disease with less risk of hyperkalemia than existing treatments. [ 2 ] [ 3 ] In 2023, KPB Biosciences entered into talks to se... | https://en.wikipedia.org/wiki/C28H30ClN5O2 |
Lecozotan is an investigational drug by Wyeth tested for improvement of cognitive functions of Alzheimer's disease patients. [ 1 ] As of June 2008 [update] , the first Phase III clinical trial has been completed. [ 2 ]
Lecozotan is a competitive, selective 5-HT 1A receptor antagonist [ 3 ] which enhances the potassium... | https://en.wikipedia.org/wiki/C28H30ClN5O3 |
Monatepil is a calcium channel blocker and α 1 -adrenergic receptor antagonist used as an antihypertensive . [ 1 ]
The synthesis of monatepil was first disclosed in patents filed by Dainippon Pharmaceutical. [ 2 ]
The amino group of the dihydrodibenzothiepin (1) is first reacted with the acid chloride of 4-chlorobuty... | https://en.wikipedia.org/wiki/C28H30FN3OS |
Darifenacin (trade name Enablex in United States and Canada, Emselex in the European Union) is a medication used to treat urinary incontinence due to an overactive bladder . [ 1 ] [ 2 ] [ 3 ] It was discovered by scientists at the Pfizer research site in Sandwich, UK under the identifier UK-88,525 and used to be market... | https://en.wikipedia.org/wiki/C28H30N2O2 |
Pemafibrate , sold under the brand name Parmodia , is a peroxisome proliferator-activated receptor alpha (PPARα) agonist . It is developed and marketed by Kowa Pharmaceuticals . [ 1 ]
In July 2017, Pharmaceuticals and Medical Devices Agency approved it in Japan. [ 2 ] [ failed verification ] | https://en.wikipedia.org/wiki/C28H30N2O6 |
SB-277,011A is a drug which acts as a potent and selective dopamine D 3 receptor antagonist , [ 1 ] which is around 80–100 times selective for D 3 over D 2 , [ 2 ] and lacks any partial agonist activity. [ 3 ]
SB-277,011A is used in the study of addiction to stimulant drugs such as nicotine [ 4 ] and cocaine . [ 5 ] [... | https://en.wikipedia.org/wiki/C28H30N4O |
SB-216641 is a drug which is a selective antagonist for the serotonin receptor 5-HT 1B , with around 25x selectivity over the closely related 5-HT 1D receptor . [ 1 ] It is used in scientific research, [ 2 ] [ 3 ] [ 4 ] and has demonstrated anxiolytic effects in animal studies. [ 5 ] [ 6 ]
This article about an anxiol... | https://en.wikipedia.org/wiki/C28H30N4O4 |
Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumours in animals, specifically dogs. [ 1 ] [ 2 ] Since its introduction in November 2008 it has been distributed under the commercial name Masivet . It has been available in Europe since the second part of 2009. Masitinib has been studied for... | https://en.wikipedia.org/wiki/C28H30N6OS |
Thymolphthalein is a phthalein dye used as an acid – base ( pH ) indicator . Its transition range is around pH 9.3–10.5. Below this pH, it is colorless; above, it is blue. The molar extinction coefficient for the blue thymolphthalein dianion is 38,000 M −1 cm −1 at 595 nm. [ 2 ]
Thymolphthalein is also known to have u... | https://en.wikipedia.org/wiki/C28H30O4 |
Herkinorin is an opioid analgesic that is an analogue of the natural product salvinorin A . It was discovered in 2005 during structure-activity relationship studies into neoclerodane diterpenes , the family of chemical compounds of which salvinorin A is a member. [ 1 ]
Unlike salvinorin A, which is a selective κ-opioi... | https://en.wikipedia.org/wiki/C28H30O8 |
Terreulactone A is a meroterpenoid isolate of Aspergillus with anti- acetylcholinesterase activity. [ 2 ] | https://en.wikipedia.org/wiki/C28H30O9 |
Nivacortol (developmental code names WIN-27914 and NEBO-174 ; also known as nivazol and nivazole ) is a synthetic glucocorticoid corticosteroid which was never marketed. [ 1 ] [ 2 ] [ 3 ] [ 4 ]
This article about a steroid is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H31FN2O |
Astemizole (marketed under the brand name Hismanal , developmental code R43512) was a second-generation antihistamine drug that has a long duration of action. Astemizole was discovered by Janssen Pharmaceutica in 1977. It was withdrawn from the market globally in 1999 because of rare but potentially fatal side effects ... | https://en.wikipedia.org/wiki/C28H31FN4O |
Cortobenzolone (brand name Tuplix ), also known as betamethasone salicylate , is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in Spain . [ 1 ] [ 2 ] [ 3 ]
This article about a steroid is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H31FO8 |
Benidipine is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension) . It is a triple L -, T -, and N -type calcium channel blocker . It is reno- and cardioprotective.
It was patented in 1981 and approved for medical use in 1991. [ 1 ]
Benidipine is dosed as 2–8 mg once dail... | https://en.wikipedia.org/wiki/C28H31N3O6 |
Firsocostat is an acetyl-CoA carboxylase inhibitor that functions in the liver. Its original designation was GS-0976 . [ 1 ] It was discovered by Nimbus Therapeutics . [ 2 ] The drug is under development by Gilead as a treatment for non-alcoholic fatty liver disease . [ 3 ] | https://en.wikipedia.org/wiki/C28H31N3O8S |
SCH-221510 is an experimental opioid drug. It has potential as an analgesic and as a treatment to addiction of certain drugs.
Most opioid analgesics act through delta , mu , and kappa opioid receptors ; however, SCH-221510 is instead an agonist at the nociceptin receptor . [ 1 ]
Classical opioid analgesics (such as m... | https://en.wikipedia.org/wiki/C28H31NO |
Bitolterol mesylate , formerly sold under the brand name Tornalate , is a short-acting β 2 -adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma [ 1 ] [ 2 ] and chronic obstructive pulmonary disease (COPD). [ 3 ] [ 4 ] [ 5 ] Bitolterol relaxes the smooth muscles present continuo... | https://en.wikipedia.org/wiki/C28H31NO5 |
VK2809 (formerly known as MB07811 ) is a thyromimetic prodrug whose active form is selective for the THR-β isoform. It is being developed by Viking Therapeutics in a phase II trial for the treatment of nonalcoholic steatohepatitis [ 1 ] [ 2 ] and is also being investigated for glycogen storage disease type Ia . [ 3 ]
... | https://en.wikipedia.org/wiki/C28H32ClO5P |
The Das cubane is a transition metal carboxylate complex with the formula [CoO(OAc)py] 4 where OAc is acetate and py is pyridine . The compound is named after Birinchi K. Das, who led the team that discovered the cluster. The compound features of Co 4 O 4 core. Each Co(III) center is low-spin and has octahedral geom... | https://en.wikipedia.org/wiki/C28H32Co4N4O12 |
Vanoxerine is an investigational drug which is being evaluated for the treatment of heart arrhythmias and cocaine dependence . Vanoxerine is a piperazine derivative which has multiple pharmacological activities including acting as an dopamine reuptake inhibitor , serotonin transporter inhibitor, and as a blocker of the... | https://en.wikipedia.org/wiki/C28H32F2N2O |
JJC8-088 is a dopamine reuptake inhibitor (DRI) that was derived from the wakefulness-promoting agent modafinil . [ 1 ] [ 2 ] [ 3 ]
It has substantially higher affinity for the dopamine transporter (DAT) than modafinil (K i = 6.72 nM vs. 2,600 nM; 387-fold). [ 2 ] In contrast to modafinil and other analogues , which a... | https://en.wikipedia.org/wiki/C28H32F2N2O2S |
BPI-16350 is a small molecule CDK4/6 inhibitor that is being studied for the treatment of cancer. [ 1 ] [ 2 ] It has a similar structure to abemaciclib but is more selective for CDK4/6 over CDK9 according to preclinical research. [ 3 ]
This pharmacology -related article is a stub . You can help Wikipedia by expanding ... | https://en.wikipedia.org/wiki/C28H32F2N8 |
A-41988 ( BW29Y ) is an analgesic drug which acts as a cannabinoid agonist . It was developed by Abbott Laboratories in the 1970s, [ 1 ] [ 2 ] and researched for potential use in the treatment of glaucoma , [ 3 ] but never commercialised.
This cannabinoid related article is a stub . You can help Wikipedia by expanding... | https://en.wikipedia.org/wiki/C28H32FNO2 |
Dexamethasone isonicotinate is an anti-inflammatory , anti-allergic glucocorticoid that can be administered orally , by inhalation , locally , and parenterally . [ 1 ] [ 2 ] [ additional citation(s) needed ] It may cause salt and water retention . [ citation needed ]
This article about a steroid is a stub . You can he... | https://en.wikipedia.org/wiki/C28H32FNO6 |
GBR-12783 is a psychostimulant which acts as a selective dopamine reuptake inhibitor . [ 1 ]
This drug article relating to the nervous system is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H32N2 |
The molecular formula C 28 H 32 N 2 O (molar mass: 412.57 g/mol, exact mass: 412.2515 u) may refer to: | https://en.wikipedia.org/wiki/C28H32N2O |
Nalfurafine ( INN , USAN ) [ 3 ] (brand name Remitch ; former developmental code names TRK-820 , AC-820 , MT-9938 ) is an antipruritic (anti-itch drug) that is marketed in Japan for the treatment of uremic pruritus in individuals with chronic kidney disease undergoing hemodialysis . [ 2 ] [ 4 ] It activates the κ-opioi... | https://en.wikipedia.org/wiki/C28H32N2O5 |
Diosmin (diosmetin 7-O-rutinoside), a flavone glycoside of diosmetin , is manufactured from citrus fruit peels as a phlebotonic non-prescription dietary supplement used to aid treatment of hemorrhoids or chronic venous diseases, mainly of the legs . [ 1 ]
Diosmin is a dietary supplement used to aid treatment of hemorr... | https://en.wikipedia.org/wiki/C28H32O15 |
Rosolutamide ( INN Tooltip International Nonproprietary Name ; developmental code name ASC-JM17 , JM17 , ALZ-003 ) is an agonist of nuclear respiratory factor 1 (NRF1), a nonsteroidal antiandrogen , and an androgen receptor degrader related to curcumin . [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ] Other analogues like dimethylcurcum... | https://en.wikipedia.org/wiki/C28H32O6 |
The molecular formula C 28 H 32 O 8 (molar mass: 496.55 g/mol, exact mass: 496.2097 u) may refer to: | https://en.wikipedia.org/wiki/C28H32O8 |
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