text stringlengths 11 320k | source stringlengths 26 161 |
|---|---|
Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic , similar to meclizine . [ 1 ]
In the United Kingdom , buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare for migraines . [ 2 ]
This drug article rel... | https://en.wikipedia.org/wiki/C28H33ClN2 |
GBR-13119 is a psychostimulant and dopamine re-uptake inhibitor . [ 1 ]
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H33FN2O |
L-371,257 is a compound used in scientific research which acts as a selective antagonist of the oxytocin receptor with over 800x selectivity over the related vasopressin receptors . [ 1 ] It was one of the first non-peptide oxytocin antagonists developed, [ 2 ] [ 3 ] [ 4 ] [ 5 ] and has good oral bioavailability, but p... | https://en.wikipedia.org/wiki/C28H33N3O6 |
Metapristone (developmental code name RU-42633 ; also known as desmethylmifepristone ) is the major metabolite of mifepristone (RU-486, RU-38486) and a selective progesterone receptor modulator (SPRM) which itself was never marketed. [ 1 ] [ 2 ] [ 3 ] [ 4 ] It is formed from mifepristone in the liver by the enzyme CYP3... | https://en.wikipedia.org/wiki/C28H33NO2 |
Cytochalasin E , a member of the cytochalasin group, is an inhibitor of actin polymerization in blood platelets. It inhibits angiogenesis and tumor growth. Unlike cytochalasin A and cytochalasin B , it does not inhibit glucose transport. Cytochalasin E, however, was noted to decrease glucose absorption in mice around t... | https://en.wikipedia.org/wiki/C28H33NO7 |
Ciprocinonide (developmental code name RS-2386 ), also known as fluocinolone acetonide cyclopropylcarboxylate , is a synthetic glucocorticoid corticosteroid which was never marketed. [ 1 ]
This article about a steroid is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H34F2O7 |
GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor . It was originally developed in its 3 H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. [ 1 ] This has led to pot... | https://en.wikipedia.org/wiki/C28H34N2O |
Denatonium , usually available as denatonium benzoate (under trade names such as Denatrol , BITTERANT-b , BITTER+PLUS , Bitrex , Bitrix , and Aversion ) and as denatonium saccharinate ( BITTERANT-s ), is the bitterest chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the ... | https://en.wikipedia.org/wiki/C28H34N2O3 |
Poncirin is the 7- O - neohesperidoside of isosakuranetin . Poncirin can be extracted from trifoliate orange ( Poncirus trifoliata ). [ 1 ]
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H34O14 |
Azadiradione is a naturally occurring compound found in several plants, most notably the neem tree ( Azadirachta indica ). It is a tetracyclic triterpenoid .
Azadiradione is the principal active ingredient in neem oil , which is extracted from the seeds of the neem tree. Smaller quantities of azadiradione can also be... | https://en.wikipedia.org/wiki/C28H34O5 |
The molecular formula C 28 H 34 O 6 (molar mass: 466.566 g/mol) may refer to: | https://en.wikipedia.org/wiki/C28H34O6 |
Ablukast ( INN ) is an experimental drug that is a leukotriene antagonist . It was investigated for potential applications in the treatment of inflammatory conditions, including asthma, skin disorders, and inflammatory bowel disease. [ 1 ] [ 2 ] It reached Phase III clinical trials, but development was discontinued in... | https://en.wikipedia.org/wiki/C28H34O8 |
Ecamsule ( USAN , trade name Mexoryl SX , INCI terephthalylidene dicamphor sulfonic acid ) is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability. [ 2 ]
Although there are a few different UV abs... | https://en.wikipedia.org/wiki/C28H34O8S2 |
Mosapramine ( Cremin ) is an atypical antipsychotic used in Japan for the treatment of schizophrenia . [ 1 ] [ 2 ] It is a potent dopamine antagonist with high affinity to the D 2 , D 3 , and D 4 receptors , [ 3 ] and with moderate affinity for the 5-HT 2 receptors . [ 4 ]
This drug article relating to the nervous sys... | https://en.wikipedia.org/wiki/C28H35ClN4O |
FCE 28260 is an azasteroidal 5α-reductase inhibitor which was developed for the treatment of benign prostatic hyperplasia and androgenic alopecia (pattern hair loss) in the 1990s but was never marketed. [ 1 ] [ 2 ] [ 3 ] FCE 28260 has been found to inhibit rat and human 5α-reductase with half-maximal inhibitory concent... | https://en.wikipedia.org/wiki/C28H35F3N2O2 |
Amcinonide (trade name Cyclocort ) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis . [ 1 ] [ 2 ] Amcinonide can also be classified as a multi-functional small molecule corticosteroid , which... | https://en.wikipedia.org/wiki/C28H35FO7 |
Capromorelin , sold under the brand names Entyce and Elura , is a medication used for the management of weight loss in cats and dogs. [ 5 ] [ 6 ] Capromorelin is a ghrelin receptor agonist known to increase appetite and weight gain. [ 2 ]
Capromorelin was developed by Pfizer . [ 7 ] [ 8 ]
Capromorelin was approved fo... | https://en.wikipedia.org/wiki/C28H35N5O4 |
Etrinabdione ( VCE-004.8 , EHP-101 ) is a drug structurally related to cannabidiol and HU-331 which has potent antiinflammatory and neuroprotective effects. It acts as a dual agonist of CB 2 and PPARγ and is in clinical trials for the treatment of scleroderma . [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ] [ 6 ] [ 7 ] [ 8 ] [ 9 ]
Thi... | https://en.wikipedia.org/wiki/C28H35NO3 |
Asoprisnil ( INN ; developmental code name J-867 ) is a synthetic , steroidal selective progesterone receptor modulator that was under development by Schering and TAP Pharmaceutical Products for the treatment of uterine fibroids . [ 1 ] In 2005, phase III clinical trials were discontinued due to endometrial changes in ... | https://en.wikipedia.org/wiki/C28H35NO4 |
FGIN-1-43 is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor , also known as the mitochondrial 18 kDa translocator protein or TSPO. It is thought to produce anxiolytic effects by stimulating steroidogenesis of neuroactive steroids such as allopregnanolone , and is several ... | https://en.wikipedia.org/wiki/C28H36Cl2N2O |
Ceritinib ( INN , [ 6 ] trade name Zykadia / z aɪ ˈ k eɪ d iː ə / zy- KAY -dee-ə ) is a prescription-only drug used for the treatment of non-small cell lung cancer (NSCLC). [ 7 ] It was developed by Novartis and received FDA approval for use in April 2014. [ 7 ]
Ceritinib is an anaplastic lymphoma kinase (ALK) inhibit... | https://en.wikipedia.org/wiki/C28H36ClN5O3S |
PF-00446687 is a drug developed by Pfizer for the treatment of erectile dysfunction , which is a non-peptide agonist selective for the melanocortin receptor subtype MC 4 . It was found to be active in preliminary human trials , with the 200mg dose being of similar effectiveness to 100mg sildenafil , though lower doses ... | https://en.wikipedia.org/wiki/C28H36F2N2O2 |
Lurasidone , sold under the brand name Latuda among others, is an atypical antipsychotic medication used to treat schizophrenia and bipolar depression . [ 2 ] It is taken by mouth .
Common side effects include sedation , indigestion , nausea , and insomnia . At higher dosages, there is an increased risk for restlessne... | https://en.wikipedia.org/wiki/C28H36N4O2S |
Crelosidenib is an investigational new drug that is being evaluated for the treatment of cancer. It acts as a selective inhibitor of isocitrate dehydrogenase 1 (IDH1), an enzyme that plays a crucial role in cellular metabolism and is frequently mutated in various cancers, including cholangiocarcinoma . [ 1 ] [ 2 ]
Th... | https://en.wikipedia.org/wiki/C28H36N6O3 |
Benzoyl-CoA is the thioester derived from benzoic acid and coenzyme A . The term benzoyl-CoA also include diverse conjugates of coenzyme A and aromatic carboxylic acids. Benzoate, vanillin , anthranilic acid , 4-ethylphenol , p-cresol , phenol , aniline , terephthalic acid , [3-hydroxybenzoic acid , and phenylalanine... | https://en.wikipedia.org/wiki/C28H36N7O17P3S |
N-0385 is an experimental small molecule TMPRSS2 -inhibitor being investigated for its potential use in the prevention and treatment of COVID-19 . [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ]
N-0385 is thought to have antiviral effects by targeting key proteins involved in the viral entry process, including TMPRSS2, ACE2 , and DPP4 ... | https://en.wikipedia.org/wiki/C28H36N8O6S2 |
Neohesperidin dihydrochalcone , sometimes abbreviated to neohesperidin DC or simply NHDC , is an artificial sweetener derived from citrus .
It is particularly effective in masking the bitter tastes of other compounds found in citrus, including limonin and naringin . Industrially, it is produced by extracting neohesper... | https://en.wikipedia.org/wiki/C28H36O15 |
Clinofibrate ( INN ; trade name Lipoclin ) is pharmaceutical drug of the fibrate class that is used for managing hyperlipidemia and associated conditions. [ 1 ] It is sold and marketed in Japan. [ 2 ]
Chemically, it is a derivative of bisphenol Z . [ 3 ]
The condensation between cyclohexanone ( 1 ) and phenol ( 2 ) g... | https://en.wikipedia.org/wiki/C28H36O6 |
Clocapramine ( Clofekton , Padrasen ), also known as 3-chloro carpipramine , is an atypical antipsychotic of the iminostilbene class which was introduced in Japan in 1974 by Yoshitomi for the treatment of schizophrenia . [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ] In addition to psychosis , clocapramine has also been used to augment... | https://en.wikipedia.org/wiki/C28H37ClN4O |
FGIN-1-27 is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor , also known as the mitochondrial 18 kDa translocator protein or TSPO. It is thought to produce anxiolytic effects by stimulating steroidogenesis of neuroactive steroids such as allopregnanolone . [ 1 ] [ 2 ] [ 3... | https://en.wikipedia.org/wiki/C28H37FN2O |
Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. It is applied as a topical cream, ointment, lotion or gel ( Diprolene ) to treat itching and other skin conditions such as eczema . Minor side effects include dry skin and mild, temporary stinging when applie... | https://en.wikipedia.org/wiki/C28H37FO7 |
Bilastine is an antihistamine medication used to treat hives ( urticaria ), allergic rhinitis and itchy inflamed eyes ( allergic conjunctivitis ) caused by an allergy. [ 6 ] It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H 1 receptor , preventing these allergic reactio... | https://en.wikipedia.org/wiki/C28H37N3O3 |
Globalagliatin ( SY-004 ) is a glucokinase activator developed by Yabao Pharmaceutical Group for type 2 diabetes. [ 1 ] [ 2 ] [ 3 ]
This drug article relating to the gastrointestinal system is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H37N3O3S3 |
BU09059 is a potent, selective, short-acting (non-"inactivating") antagonist of the κ-opioid receptor (KOR). [ 1 ] [ 2 ] It was derived from the irreversible (long-acting) KOR antagonist JDTic in search of an antagonist with a reversible profile of inactivation of the KOR that could be used with less concern to treat p... | https://en.wikipedia.org/wiki/C28H37N3O5 |
Pristinamycin IIB is an antibiotic of the streptogramin A class. It was isolated from Streptomyces pristinaespiralis [ 1 ] and its chemical structure was first determined in 1966. [ 2 ]
This systemic antibiotic -related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H37N3O7 |
Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans. [ 2 ] [ 3 ] It is one of the two forms of enkephalin ; the other is met-enkephalin . [ 2 ] The tyrosine residue at position 1 is thoug... | https://en.wikipedia.org/wiki/C28H37N5O7 |
Vicriviroc , previously named SCH 417690 and SCH-D, is a pyrimidine CCR5 entry inhibitor of HIV-1 . It was developed by the pharmaceutical company Schering-Plough . Merck decided to not pursue regulatory approval for use in treatment-experienced patients because the drug did not meet primary efficacy endpoints in late... | https://en.wikipedia.org/wiki/C28H38F3N5O2 |
Flopristin is a semi-synthetic antibiotic of the streptogramin A class. It is a fluorinated derivative of pristinamycin IIB . [ 1 ]
Flopristin is one of the components of the experimental drug NXL103 . [ 1 ]
This systemic antibiotic -related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H38FN3O6 |
SER-601 ( COR-167 ) is a drug which acts as a potent and selective cannabinoid CB 2 receptor agonist , based on a quinolone -3- carboxylic acid core structure, with 190 times selectivity for CB 2 over the related CB 1 receptor . It has analgesic effects in animal studies, as well as neuroprotective effects, [ 1 ] but w... | https://en.wikipedia.org/wiki/C28H38N2O2 |
Cephaeline is an alkaloid that is found in Cephaelis ipecacuanha and other plant species including Psychotria acuminata . [ 1 ] Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac . [ 2 ] Chemically, it is closely related to emetine .
Cephaeline in ... | https://en.wikipedia.org/wiki/C28H38N2O4 |
Carpipramine ( Prazinil , Defekton ) is an atypical antipsychotic used for the treatment of schizophrenia and anxiety in France and Japan . [ 1 ] [ 2 ] [ 3 ] [ 4 ] In addition to its neuroleptic and anxiolytic effects, carpipramine also has hypnotic properties. [ 3 ] It is structurally related to both tricyclics like i... | https://en.wikipedia.org/wiki/C28H38N4O |
FGI-106 is a broad-spectrum antiviral drug developed as a potential treatment for enveloped RNA viruses, in particular viral hemorrhagic fevers from the bunyavirus , flavivirus and filovirus families. It acts as an inhibitor which blocks viral entry into host cells. In animal tests FGI-106 shows both prophylactic and c... | https://en.wikipedia.org/wiki/C28H38N6 |
Sucrose octaacetate is a chemical compound with formula C 28 H 38 O 19 or (C 2 H 3 O 2 ) 8 (C 12 H 14 O 3 ) , an eight-fold ester of sucrose and acetic acid . Its molecule can be described as that of sucrose C 12 H 22 O 11 with its eight hydroxyl groups HO – replaced by acetate groups H 3 C–CO 2 –. It is a crystallin... | https://en.wikipedia.org/wiki/C28H38O19 |
Nandrolone cyclotate ( USAN Tooltip United States Adopted Name ) (developmental code name RS-3268R ), or nandrolone ciclotate , also known as 19-nortestosterone 17β-ciclotate , is a synthetic and injected anabolic–androgenic steroid (AAS) of the nandrolone (19-nortestosterone) group which was never marketed. [ 1 ] [ 2 ... | https://en.wikipedia.org/wiki/C28H38O3 |
Withaferin A is a steroidal lactone , derived from Acnistus arborescens , [ 1 ] Withania somnifera [ 2 ] and other members of family Solanaceae . It is the first member of the withanolide class of ergostane type product to be discovered.
Withanolides are a group of naturally occurring C28- steroidal lactones . They co... | https://en.wikipedia.org/wiki/C28H38O6 |
SNC-80 is an opioid analgesic compound that selectively activates μ–δ opioid receptor heteromers [ 1 ] and is used primarily in scientific research. [ 2 ] Discovered in 1994, SNC-80 was a pioneering non-peptide compound regarded as a highly selective agonist for the δ-opioid receptor. [ 3 ]
SNC-80 was the first non- p... | https://en.wikipedia.org/wiki/C28H39N3O2 |
JDTic is a selective , long-acting ("inactivating") antagonist of the κ-opioid receptor (KOR). [ 1 ] [ 2 ] JDTic is a 4-phenylpiperidine derivative, distantly related structurally to analgesics such as pethidine and ketobemidone , and more closely to the MOR antagonist alvimopan . In addition, it is structurally distin... | https://en.wikipedia.org/wiki/C28H39N3O3 |
Rotigaptide ( ZP-123 ) is a drug under clinical investigation for the treatment of cardiac arrhythmias – specifically atrial fibrillation . It is a peptide analog that has been shown to increase gap junction intercellular conductance in cardiac muscle cells . [ 1 ] Gap junctions are protein channels that are responsibl... | https://en.wikipedia.org/wiki/C28H39N7O9 |
Aflavinine is an anti-insectan chemical compound produced by some plants and fungi. [ 1 ] [ 2 ] [ 3 ] | https://en.wikipedia.org/wiki/C28H39NO |
Gallopamil ( INN ) is an L-type calcium channel blocker that is an analog of verapamil . It is used in the treatment of abnormal heart rhythms . [ 1 ]
The alkylation reaction of 3,4,5-trimethoxyphenylacetonitrile (1) and isopropyl chloride (2), using sodium amide as base gives the intermediate nitrile (3). A second al... | https://en.wikipedia.org/wiki/C28H40N2O5 |
Antimycin A (more exactly antimycin A1b ) is a secondary metabolite produced by Streptomyces bacteria [ 1 ] and a member of a group of related compounds called antimycins . Antimycin A is classified as an extremely hazardous substance in the United States, as defined in Section 302 of the U.S. Emergency Planning and C... | https://en.wikipedia.org/wiki/C28H40N2O9 |
Estradiol cyclooctyl acetate ( E 2 COA ), or estradiol 17β-cyclooctylacetate , also known as estra-1,3,5(10)-triene-3,17β-diol 17β-cyclooctylacetate , is an estrogen medication and an estrogen ester – specifically, the 17β- cyclooctyl acetate ester of estradiol – which has been studied for use in hormone replacement th... | https://en.wikipedia.org/wiki/C28H40O3 |
The molecular formula C 28 H 40 O 4 (molar mass: 440.615 g/mol, exact mass: 440.2927 u) may refer to: | https://en.wikipedia.org/wiki/C28H40O4 |
Butagest , also known as buterol is a modification of megestrol acetate in which the C-3 ketone has been replaced by a C3β butanoyloxy moeity. [ 1 ] It is chemically known as 3β-hydroxy-6-methyl-17α-hydroxypregna-4,6-dien-20-one 3β-butanoate 17α-acetate or 6-methyl-17α-hydroxy-δ 6 -progesterone 3β-butanoate 17α-acetat... | https://en.wikipedia.org/wiki/C28H40O5 |
CPhos is a phosphine ligand derived from biphenyl . It is a white solid that is soluble in organic solvents.
Its palladium complexes exhibit high activity for Negishi coupling reactions involving aryl bromides, chlorides and triflates . CPhos mediated reactions performed with secondary (sp 3 ) alkylzinc halides often... | https://en.wikipedia.org/wiki/C28H41N2P |
The molecular formula C 28 H 41 N 3 O 3 (molar mass: 467.643 g/mol, exact mass: 467.3148 u) may refer to: | https://en.wikipedia.org/wiki/C28H41N3O3 |
N -Arachidonoyl dopamine ( NADA ) is an endocannabinoid that acts as an agonist of the CB 1 receptor and the transient receptor potential V1 (TRPV1) ion channel . NADA was first described as a putative endocannabinoid (agonist for the CB 1 receptor) in 2000 [ 1 ] and was subsequently identified as an endovanilloid (ago... | https://en.wikipedia.org/wiki/C28H41NO3 |
O-2372 is an analgesic cannabinoid derivative created by Organix Inc . for use in scientific research. It has high affinity for both CB 1 and CB 2 receptors , with K i values of 1.3 nM at CB 1 and 0.57 nM at CB 2 , but is only moderately soluble in water compared to other related compounds such as O-2694 , which it is ... | https://en.wikipedia.org/wiki/C28H41NO4 |
SC-17599 is a steroid derivative drug discovered in 1968 which acts as a selective μ-opioid receptor agonist , with little or no affinity for the δ-opioid or κ-opioid receptors. It is an active analgesic in vivo , more potent than codeine or pethidine but slightly less potent than morphine , [ 1 ] and produces similar ... | https://en.wikipedia.org/wiki/C28H42FNO4 |
Difebarbamate ( INN ) is a tranquilizer of the barbiturate and carbamate families which is used in Europe as a component of a combination drug formulation referred to as tetrabamate ( Atrium , Sevrium ). [ 1 ] [ 2 ] [ 3 ] | https://en.wikipedia.org/wiki/C28H42N4O9 |
Polyvinyl acetate ( PVA , PVAc , poly(ethenyl ethanoate) ), commonly known as wood glue (a term that may also refer to other types of glues ), PVA glue , white glue , carpenter's glue , school glue , or Elmer's Glue in the US, is a widely available adhesive used for porous materials like wood, paper, and cloth. An alip... | https://en.wikipedia.org/wiki/C28H42O14 |
The molecular formula C 28 H 42 O 4 (molar mass: 442.63 g/mol) may refer to: | https://en.wikipedia.org/wiki/C28H42O4 |
Borrelidin is an 18-membered polyketide macrolide derived from several Streptomyces species. First discovered in 1949 from Streptomyces rochei , [ 1 ] Borrelidin shows antibacterial activity by acting as an inhibitor of threonyl-tRNA synthetase and features a nitrile moiety, a unique functionality in natural products .... | https://en.wikipedia.org/wiki/C28H43NO6 |
Gedunin is a pentacyclic triterpenoid with the molecular formula C 28 H 34 O 7 . It is most notably found in Azadirachta indica , [ 1 ] but is a constituent of several other plants. Gedunin shows therapeutic potential in the treatment of leukemia , [ 2 ] and Parkinson's disease . [ 3 ] [ 4 ]
Azadirachta indica [ 5 ] i... | https://en.wikipedia.org/wiki/C28H43O7 |
Doxercalciferol (or 1-hydroxyergocalciferol , trade name Hectorol ) is drug for secondary hyperparathyroidism and metabolic bone disease . [ 1 ] It is a synthetic analog of ergocalciferol (vitamin D 2 ). It suppresses parathyroid synthesis and secretion. [ 2 ]
Doxercalciferol is the vitamin D 2 analogue of alfacalci... | https://en.wikipedia.org/wiki/C28H44O2 |
Antillatoxin ( ATX ) is a potent lipopeptide neurotoxin produced by the marine cyanobacterium Lyngbya majuscula . ATX activates voltage-gated sodium channels , which can cause cell depolarisation, NMDA-receptor overactivity, excess calcium influx and neuronal necrosis.
Antillatoxin is found in the venom of the marine ... | https://en.wikipedia.org/wiki/C28H45N3O5 |
Cerevisterol (5α-ergosta-7,22-diene-3β,5,6β-triol) is a sterol . Originally described in the 1930s from the yeast Saccharomyces cerevisiae , it has since been found in several other fungi and, recently, in deep water coral . Cerevisterol has some in vitro bioactive properties, including cytotoxicity to some mammalian c... | https://en.wikipedia.org/wiki/C28H46O3 |
Hippuristanol is a small molecule found in the coral Isis hippuris [ 1 ] which was discovered by Jerry Pelletier and others of McGill University in Montreal, Quebec , Canada. [ 2 ] It appears to have anti-viral activity and may hold promise as a cancer therapy. [ 3 ] Binds to and inhibits the eukaryotic translation in... | https://en.wikipedia.org/wiki/C28H46O5 |
Butyrolactol A is an organic chemical compound of interest for its potential use as an antifungal antibiotic.
One of a number of potentially useful substances derived from the bacteria Streptomyces rochei , it demonstrates broad antimicrobial activity against fungi, including Candida albicans . [ 1 ] [ 2 ] Butyrolacto... | https://en.wikipedia.org/wiki/C28H46O9 |
Tiamulin (previously thiamutilin ) is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry. [ 1 ] [ 2 ]
Tiamulin is a diterpene antimicrobial with a pleuromutilin chemical structure similar to that of valnemulin . [ 3 ]
This systemic antibiotic -related article is a st... | https://en.wikipedia.org/wiki/C28H47NO4S |
Bisnorhopanes (BNH) are a group of demethylated hopanes found in oil shales across the globe and can be used for understanding depositional conditions of the source rock. The most common member, 28,30-bisnorhopane, can be found in high concentrations in petroleum source rocks , most notably the Monterey Shale, as well ... | https://en.wikipedia.org/wiki/C28H48 |
MK-386 , also known as 4,7β-dimethyl-4-aza-5α-cholestan-3-one , is a synthetic , steroidal 5α-reductase inhibitor which was first reported in 1994 and was never marketed. [ 1 ] [ 2 ] It is a 4-azasteroid and a potent and selective inhibitor of 5α-reductase type I and shows high selectivity for inhibition of human 5α-re... | https://en.wikipedia.org/wiki/C28H49NO |
Carpaine is one of the major alkaloid components of papaya leaves which has been studied for its cardiovascular effects. [ 2 ] Carpaine extracted from Carica papaya trees has been reported to have diverse biological properties, such as anti-malarial , anti-inflammatory , anti-oxidant , and vasodilatory effects. [ 3 ] E... | https://en.wikipedia.org/wiki/C28H50N2O4 |
Epoxomicin is a naturally occurring selective proteasome inhibitor with anti-inflammatory activity. [ 2 ] It was originally discovered in 1992. [ 3 ] Injected, it can induce Parkinson's -like symptoms in rats.
Derivatives of epoxomicin include carfilzomib .
This antineoplastic or immunomodulatory drug article is a st... | https://en.wikipedia.org/wiki/C28H50N4O7 |
Campestanol is a natural phytosterol . [ 1 ]
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C28H50O |
Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (abbreviated BTMPS ) is a hindered amine light stabilizer used to protect plastics and coatings such as paint from oxidation caused by weathering. Like most compounds of this class, the activated form is an aminoxyl radical .
It is produced by the di esterification of seba... | https://en.wikipedia.org/wiki/C28H52N2O4 |
Gadopentetic acid , sold under the brand name Magnevist , is a gadolinium -based MRI contrast agent . [ 2 ]
It is usually administered as a salt of a complex of gadolinium with DTPA ( d iethylene t riamine p ent a cetate) with the chemical formula A 2 [Gd(DTPA)(H 2 O)]; when cation A is the protonated form of the amin... | https://en.wikipedia.org/wiki/C28H54GdN5O20 |
Montanic acid is a saturated fatty acid isolated and detected mainly in montan wax . It also occurs in beeswax and Chinese wax . Montanic acid ethylene glycol esters and glycerol esters are used as protective layer on fruit skins and coating on foods. [ 1 ] It is known as E number reference E912 . | https://en.wikipedia.org/wiki/C28H56O2 |
Higher alkanes refer to alkanes with a high number of carbon atoms. There does not exist a formal definition for when an alkane is classified as a 'higher alkane', but one definition says higher alkanes are alkanes having nine or more carbon atoms. Thus, according to this definition, nonane is the lightest higher alkan... | https://en.wikipedia.org/wiki/C28H58 |
1-Octacosanol [ pronunciation? ] (also known as n -octacosanol, octacosyl alcohol, cluytyl [ pronunciation? ] alcohol, montanyl [ pronunciation? ] alcohol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is common in the epicuticular waxes of plants, including the leaves of many species of Eucalyptus... | https://en.wikipedia.org/wiki/C28H58O |
Pluronic P123 is a symmetric triblock copolymer comprising poly( ethylene oxide ) (PEO) and poly( propylene oxide ) (PPO) in an alternating linear fashion, PEO-PPO-PEO. The unique characteristic of PPO block, which is hydrophobic at temperatures above 288 K and is soluble in water at temperatures below 288 K, leads to ... | https://en.wikipedia.org/wiki/C290H582O111 |
Pegaptanib [ 2 ] sodium injection (brand name Macugen ) is an anti-angiogenic medicine for the treatment of neovascular (wet) age-related macular degeneration (AMD). [ 3 ] It was discovered by NeXstar Pharmaceuticals (which merged with Gilead Sciences in 1999) and licensed in 2000 to EyeTech Pharmaceuticals, now OSI Ph... | https://en.wikipedia.org/wiki/C294H342F13N107Na28O188P28 |
Carboxyfluorescein diacetate succinimidyl ester ( CFDA-SE ) is an amine -reactive, cell -permeable dye generally used in animal cell proliferation research. CFDA-SE is a modified CFSE with two hydroxyl groups on its fluorescein moiety replaced with acetates . This change renders the molecule more hydrophobic and cell-p... | https://en.wikipedia.org/wiki/C29H19NO11 |
Tetraphenylcyclopentadienone is an organic compound with the formula (C 6 H 5 C) 4 C 4 C=O . It is classified as a cyclic dienone . It is a dark purple to black crystalline solid that is soluble in organic solvents. It is an easily made building block for many organic and organometallic compounds .
The C 5 O core of ... | https://en.wikipedia.org/wiki/C29H20O |
Hopeanol is a highly cytotoxic resveratrol -derivative with the molecular formula C 29 H 20 O 9 which has been isolated from the bark of the tree Hopea exalata (now Hopea reticulata ). [ 2 ] [ 1 ] [ 3 ] [ 4 ]
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C29H20O9 |
HEC96719 is a tricyclic farnesoid X receptor agonist developed for non-alcoholic steatohepatitis. [ 1 ] [ 2 ] [ 3 ] | https://en.wikipedia.org/wiki/C29H22Cl2N2O5 |
Imlunestrant is an experimental selective estrogen receptor degrader developed by Eli Lilly and Company for the treatment of some types of breast cancer . [ 1 ] [ 2 ] [ 3 ] | https://en.wikipedia.org/wiki/C29H24F4N2O3 |
Theaflavin (TF) and its derivatives, known collectively as theaflavins , are antioxidant polyphenols that are formed from the condensation of flavan-3-ols in tea leaves during the enzymatic oxidation (sometimes erroneously referred to as fermentation ) of black tea . Theaflavin-3-gallate , theaflavin-3'-gallate, and th... | https://en.wikipedia.org/wiki/C29H24O12 |
Thelephantins are a group of pigments found in the inedible mushroom Thelephora aurantiotincta . Chemically, they are classified as polyphenols and terphenyl derivatives.
Three variants (thelephantin A, B, C) have been elucidated by high-resolution 2D nuclear magnetic resonance, mass spectroscopy , infrared and ultra... | https://en.wikipedia.org/wiki/C29H24O9 |
Nicomorphine ( Vilan , Subellan , Gevilan , MorZet ) is the 3,6-dinicotinate ester of morphine . It is a strong opioid agonist analgesic two to three times as potent as morphine with a side effect profile similar to that of dihydromorphine , morphine, and diamorphine .
Nicomorphine was first synthesized in 1904 and wa... | https://en.wikipedia.org/wiki/C29H25N3O5 |
Bexirestrant is a selective estrogen receptor degrader (SERD) which is being evaluated for the treatment of breast cancer . This orally bioavailable compound has demonstrated potent activity against both wild-type and mutant forms of the estrogen receptor (ER), addressing a critical need in overcoming resistance to cur... | https://en.wikipedia.org/wiki/C29H26F3NO2 |
CDD-2807 is a chemical compound which acts as a potent and selective inhibitor of serine/threonine-protein kinase 33 ( STK33 ), with a IC 50 of 9.2 nM. In animal studies it causes production of abnormal sperm with reduced motility, and it has been investigated as a potential male contraceptive drug. [ 1 ] [ 2 ]
This p... | https://en.wikipedia.org/wiki/C29H26N4O |
Opnurasib (JDQ-443) is a small-molecule covalent KRASG12C inhibitor developed for non-small-cell lung cancer . [ 1 ] [ 2 ] [ 3 ] [ 4 ]
This pharmacology -related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C29H28ClN7O |
JBI-589 is an experimental drug which acts as an orally active, selective inhibitor of the enzyme peptidylarginine deiminase 4 (PAD4). It has antiinflammatory effects and has been researched for potential use in the treatment of arthritis and some forms of cancer . [ 1 ] [ 2 ] [ 3 ] [ 4 ] | https://en.wikipedia.org/wiki/C29H28FN5O |
Clocinnamox ( CCAM or C-CAM ; developmental code name NIH-10443 ) is a selective and irreversible antagonist of the μ-opioid receptor . [ 1 ] [ 2 ] Closely related compounds include methocinnamox (MCAM) and methoclocinnamox (MCCAM). [ 1 ] [ 3 ] [ 4 ] [ 5 ] They were derived via structural modification of buprenorphine ... | https://en.wikipedia.org/wiki/C29H29ClN2O4 |
Cadazolid is an experimental antibiotic of the oxazolidinone class made by Actelion Pharmaceuticals Ltd. which is effective against Clostridioides difficile , a major cause of drug resistant diarrhea in the elderly. [ 1 ] Current drug treatments for this infection involve orally delivered antibiotics, principally fidax... | https://en.wikipedia.org/wiki/C29H29F2N3O8 |
Dagrocorat (developmental code names PF-00251802 , PF-251802 ) is a nonsteroidal but steroid -like selective glucocorticoid receptor modulator (SGRM) which was under development for the treatment of rheumatoid arthritis but was never marketed. [ 1 ] [ 2 ] [ 3 ] [ 4 ] It is described as a partial agonist and "dissociabl... | https://en.wikipedia.org/wiki/C29H29F3N2O2 |
Befetupitant ( Ro67-5930 ) is a drug developed by Hoffmann-La Roche which acts as a potent and selective antagonist for the NK 1 receptor . [ 1 ] It was originally developed as a potential antiemetic drug, though development was ultimately discontinued after a related drug netupitant was deemed to be more suitable for ... | https://en.wikipedia.org/wiki/C29H29F6N3O2 |
Olmesartan , sold under the brand name Benicar among others, is a medication used to treat high blood pressure ( hypertension ). [ 1 ] [ 2 ] It is taken orally (swallowed by mouth). [ 2 ] Versions are available as the combination olmesartan/hydrochlorothiazide and olmesartan/amlodipine . [ 2 ] It is available as a prod... | https://en.wikipedia.org/wiki/C29H30N6O6 |
Amarogentin is a chemical compound found in gentian ( Gentiana lutea ) or in Swertia chirata . [ 1 ]
Gentian root has a long history of use as a herbal bitter in the treatment of digestive disorders and is an ingredient of many proprietary medicines. The bitter principles of gentian root are secoiridoid glycosides ama... | https://en.wikipedia.org/wiki/C29H30O13 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.