accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 16 2.75k | function stringlengths 6 5.51k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q6CQX5 | AIM21_KLULA | Altered inheritance of mitochondria protein 21 | Kluyveromyces | MEQVIPKVPERPRRRITRSEEPEQLRSESEFEREKSGSKDSELDLPPVPKTRPNRKPLASSSAHASSDDVSVKPEPQIQAQLQPEAVIETEPTVEHPIVDELEAKLPVEQPVLDEVELDEPVTQEVEPSGELLPEESTIKESLEEQIIDDFADEPVEEECKEVASPELIGDEAIQDEELEKPVKEEPIIQTDDKTLAEAIVPSVCEESEADIAEEPKETPEDASEAVVEAAREESSEVSPEASPEVPPEKTQVSVDQLSSTANLTEGAKEAPKEEQKETSEATSEETPEDSSVNAKPLFKEVTPGNVSSKEAIPSNTSPK... | Involved in mitochondrial migration along actin filaments. | Q6CQX5 |
B2FIC0 | DAPE_STRMK | N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase | Stenotrophomonas maltophilia group | MSAVLDLTCELIARPSVTPDDAGCQALLAARLKQAGFQCDHLRLGDVDNLWATHGLGAPVLVLLGHTDVVPTGPRESWTSDPFTPHIRDGVLYGRGAADMKGSVAAFVVAAEQFVADHPDHPGTLAVLLTSDEEGDAIDGVRHVARLFAARGQRIDWCITGEPSSTATLGDLLRVGRRGSLSAKLRVQGVQGHVAYPEKARNPIHQAAPALAELCARRWDDGYESFPPTSLQISNIHAGTGANNVIPGELDVDFNIRYNPHWDAPKLEAEITALLERHGLQYTLKWHRSGEPFYTPEGTLRAIARAVLAEHIGRAPEEST... | Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | B2FIC0 |
Q126M0 | TRPA_POLSJ | Tryptophan synthase alpha chain | unclassified Polaromonas | MSRIASTFSALKSQGRKALIPYVTAGFPFADITPELMHSMVAGGADVIELGVPFSDPSADGPVIQKAGEKALALGIGLAQVLEMVRVFRQKDGTTPVVLMGYANPVERYDIKHGGSATESAFIRDAAQAGVDGVLIVDYPPEECVEFAARLRAHNMDLIFLLAPTSTSARMAQVAEVASGYVYYVSLKGVTGAGTLDVDAVEAMLPRIRQHVKVPVGVGFGIRDAATAKAIGKVADAVVIGSKIIQLIENQPRDKVATVARDFLKEIRAALD | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | Q126M0 |
Q5L6D8 | DUT_CHLAB | dUTP pyrophosphatase | Chlamydia | MTILCELESGVSLPEYATEGASGADLRANIKEPMAVLPGQRVLVPTGIKMQIPQGYEVQVRPRSGFALKHGIMVVNSPGTIDADYRGEVCIILANFGESTFIIEPKMRIAQAVVAPVVQAKFIAVDQEEGLTTTSRGSRGFGHTGEK | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Q5L6D8 |
Q31C00 | ACCA_PROM9 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Prochlorococcus | MAKRYLLDFEKPLVELEKQIEQIKELARDSEVDVSQQLLQLETLATRRREEIFKSLTPAQKIQVARHPQRPSTLDFVQMFCDDWIELHGDRNGGDDMALIGGIGSINNRPVLMLGHQKGRDTKENVVRNFGMAKPGGYRKALRLMQHADRFSLPILTFIDTPGAYAGLTAEEQGQGEAIARNLREMFGLTVPIVATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAAKAPEAASALKITGKDLLKLGIIDEVLPEPSGGNNWAPLDAGNTLKEAIEKHLDTLLQMTKDELIEERYKKFRVLGKFIEA... | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Q31C00 |
Q8DC50 | RECX_VIBVU | Regulatory protein RecX | Vibrio | MHHRFTPPMMSCKDTAIQLLSRRDHGQYELRQKLTVKGYASQDIESAMHFCLEHGYLDDLRYAKSQIRQHVGKGHGERRIRQELSLKQVSDSVVENAFAEEPQDWFELAKSVAMKKFNGVKAKEQKEYAKQVRFLQYRGFSFEQIRYALSDEA | Modulates RecA activity. | Q8DC50 |
P75167 | GPMI_MYCPN | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Mycoplasma | MHKKVLLAILDGYGISNKQHGNAVYHAKTPALDSLIKDYPCVMLEASGEAVGLPQGQIGNSEVGHLNIGAGRIVYTGLSLINQNIKTGAFHHNQVLLEAIARAKANNAKLHLIGLFSHGGVHSHMDHLYALIKLAAPQVKMVLHLFGDGRDVAPCTMKSDLEAFMVFLKDYHNVIIGTLGGRYYGMDRDQRWDREEIAYNAILGNSKASFTDPVAYVQSAYDQKVTDEFLYPAVNGNVDKEQFALKDHDSVIFFNFRPDRARQMSHMLFQTDYYDYTPKAGRKYNLFFVTMMNYEGIKPSAVVFPPETIPNTFGEVIAHN... | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. | P75167 |
B1YMH0 | MIAA_EXIS2 | Isopentenyl-diphosphate:tRNA isopentenyltransferase | Exiguobacterium | MSLSKQPVIVIVGPTAVGKTKTGIELAKKLNGEIISGDSVQVYKQMDIGSAKVTQEEMEGIPHHLLDLVDPDDEMSVARFQTLARTAIDEIAAKGKLPIIVGGTGLYIRAILYDYQFTVQAENKVLREELEQFAQAEGATALHDRLRQLDAKRADEIHPNNIQRVVRAIEVAMSGQTQVSGSEPSLYDSLLFVLHMEDREQLYDRIDQRVDLMIEQGLVAEVDRLVAAGYRDTKAMQAIGYKEIVPVLEGAPLEPAVEQLKRNTRRFAKRQLTWFRHQFDGNWIEMGRLSFEENFKIIYDRTVGFLKAVKSE | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | B1YMH0 |
P95435 | PSCG_PSEAE | Pseudomonas secretion protein G | Pseudomonas | MDTSLIRELAELALAGSGQHCHEEALCIAEWLERLGQDEAARLIRISSLANQGRYQEALAFAHGNPWPALEPWFALCEWHLGLGAALDRRLAGLGGSSDPALADFAAGMRAQVRT | Chaperone of the type III secretion (T3S) injectisome that translocates effector toxins into host cells, facilitating the establishment and dissemination of infection. Prevents premature polymerization of PscF, along with PscE, within the cytoplasm . Required for type III secretion needle assembly. Also required for cy... | P95435 |
Q10YT5 | NDHJ_TRIEI | NDH-1 subunit J | Trichodesmium | MAESEAPIIEAGKVSKWLTDNGFDHEFLAPDHQGIEIIKGNRDFLIPLATALYAYGFNYLQCQCAYDAGPGEDLVSMYHLVKVSDDVEQPEEIRLKVFVPRDDPRLPSVYWIWKSADFQERESYDMYGIIYEGHPNLKRILMPEDWVGWPLRKDYISPEFYELQDAY | NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus co... | Q10YT5 |
A1VYA6 | DER_CAMJJ | GTP-binding protein EngA | Campylobacter | MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLDESDELFKNVKKNTLKVAKESDIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVVNKVDNKKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFLHEEFLIPDEEENLEDFLEHYEEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVHKDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGLVAKHYLGVIIVLNKWDKSEM... | GTPase that plays an essential role in the late steps of ribosome biogenesis. | A1VYA6 |
P86247 | K2C8_MESAU | Keratin-8 | Mesocricetus | MSTSGPRAFSSRFASFIDKVRWSLLQQQKSNMDNMFESYINNLRDVDEAYMNKVELESRLEGLTDEINFLRQIHEEEIRSLDMDSIIAEVRHGDDLRRLALDIEIATYRK | Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. | P86247 |
Q9LQI7 | CIA30_ARATH | Probable complex I intermediate-associated protein 30 | Arabidopsis | MSRFRSLLQASVNATKKALTWNVEEWVPPAEKHIFKFHSKEDLKKWHLYSDSEYGGLSSASLEIPDKGDGSDCTGVFSGNLSVDLSEGSKWNISRSGFCGMRSKKFDGFIDLDGYDAIALRIRGDGRCYISTIYTENWVNSPGQSEDNSWQAFVFAPKDSWYTAKIPLARYLPTWRGNVIDVEMEMNPGRVLGMSLSVNAEGGAVGAKSGAGDFRVEIDWIKALRLP | Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | Q9LQI7 |
Q0APW4 | EFTS_MARMM | Elongation factor Ts | Maricaulis | MAGITAALVKELRDKTGVGMMDCKKALGETDGDFEAAVDWLRKKGLSKAAKKADRVAAEGLVAVATQGGQGAVVEVNSETDFVARNEKFQTAVKEIAALAIGGSGDVAEIKAASTSGGSTVEDHLTNLIATIGENMALRRAAVVVAEPGVVASYVHNPAATDMGAIGVLVGLQSDGDKDKLAELGRKIAMHVAAGSPAVAVSVDVDGVDSAIADKEREVFADQARQAGKPDSIVEKMVEGRMRKFYEEVVLLKQAFVMDPDNTIEQVLEAAAKDLGAPVTISGFVRMALGEGVEKGPEEDFAAEVAAASGQS | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. | Q0APW4 |
P10583 | GLN1B_AZOBR | Glutamine synthetase I beta | Azospirillum | MSDISKVFDLIKEHDVKYVDLRFTDPRGKLHHTAQHVSTIDEDVFEDGIMFDGSSIAGWKAINESDMILQLDPTTAVMDPFSAQPTLNILCDVYEPSTGQPYARCPRGIAKAAEKYMASAGIADTAYFGPEAEFFVFDDVKFKVEMNKVSYEFDSEEGPYTSDKDYEDGNLGHRPGVKGGYFPVAPVDSGSDLRAEMLSVLAEMGVPVEKHHHEVAASQHELGIKFDTLVRTGDNMQYYKYVVHNVAHAYGKTATFMPKPVFGDNGSGMHMHQSIWKEGQPLFAGNQYADLSELALYYIGGIIKHAKALNAFTNPTTNSY... | Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. | P10583 |
A7FIZ3 | UVRC_YERP3 | Excinuclease ABC subunit C | Yersinia | MTDLFDYKEFLKTVTSQPGVYRMYDTAGTVIYVGKAKDLKKRLTSYFRAQVANRKTETLVKNIAQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPLIFLSADEHPRLAVHRGAKHEKGEYFGPFPNSYAVRETLALLQKLFPVRQCENSVYRNRSRPCLQYQIGRCSGPCVEGLVSEEEYQRQVDYVRLFLSGKDQQVLTQLITRMEEASQQLHFEDAARIRDQIQAVRRVTEQQFVSGDSEDLDVIGVAFDAGLACVHVLFIRLGKVLGSRSYFPKVPAGTELSEVVQTFVGQFYLQGSQGRTLPGEILLD... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | A7FIZ3 |
A7X1Z0 | RS14_STAA1 | 30S ribosomal protein S14 | Staphylococcus | MAKKSKIAKERKREELVNKYYELRKELKAKGDYEALRKLPRDSSPTRLTRRCKVTGRPRGVLRKFEMSRIAFREHAHKGQIPGVKKSSW | Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | A7X1Z0 |
O04706 | GAO1B_WHEAT | TaGA20ox1-B | Triticum | MVQPVFDAAVLSGRADIPSQFIWPEGESPTPDAAEELHVPLIDIGGMLSGDPRATAEVTRLVGEACERHGFFQVVNHGIDAELLADAHRCVDAFFTMPLPEKQRALRRPGESCGYASSFTGRFASKLPWKETLSFRSCPSDPALVVDYIVATLGEDHRRLGEVYARYCSEMSRLSLEIMEVLGESLGVGRAHYRRFFEGNDSIMRLNYYPPCQRPMETLGTGPHCDPTSLTILHQDNVGGLQVHTEGRWRSIRPRADAFVVNIGDTFMALSNGRYKSCLHRAVVNSKVPRKSLAFFLCPEMDKVVAPPGTLVDAANPRAY... | Key oxidase enzyme in the biosynthesis of gibberellin that catalyzes the conversion of GA12 and GA53 to GA9 and GA20 respectively, via a three-step oxidation at C-20 of the GA skeleton. | O04706 |
P56449 | OXYR_BOVIN | Oxytocin receptor | Bos | MEGAFAANWSAEAVNGSAAPPGTEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLSRRTDRLAVLVTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLATCYGLISFKIWQNLRLKTAAAAAEAAAGAEGEAADWAGRAILARVSNVKLISKAKIRTVKMTFIVVLAFIVCWTPFFFVQMWSVWDADAPKEASPFIIAMLLA... | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. | P56449 |
Q2HJ52 | TBP_BOVIN | Transcription initiation factor TFIID TBP subunit | Bos | MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQAAVAAVQQSTSQQATQGPSGQTPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT | General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-conta... | Q2HJ52 |
Q36445 | CYB_MYCVI | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Mycena | MRIFKTNVLLRFVNSYIIDSPQPANLSYLWNFGSLLALCLIIQILTGCFLAMHYIPNVDLAFDSIEHIMRDVDNGYILRYTHANVASFFFIFIYVHIGRGLWYGSYRAPRVLLWSIGVIILVLMMAIGFLGYVLPFGQMSLWGATVITNLLSAIPIFGQDIVELIWGGFSVSNATLNRFFSLHYILPFVLAALAVAHMIALHTHGSSNPNGLTSNGDRYAMYPYFIFKDLVTIFAFFLVLSIIVFFYPNLMGHSDNYIPANPMVTPSSIVPEWYLLPFYAILRSIPNKLLGVLAMFGSLLILLIMPFVDFSRTRGNKTLN... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q36445 |
B7HZH8 | HPR_BACC7 | Protease production regulatory protein Hpr | Bacillus cereus group | MKSGEKDYSVKEAMIFSQRIAQLSKALWKCVEKDWQMWIKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDDKRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIELIAILRNIYGQDFIDIFEKSLEDIEENFTESDQKLVKK | Negative regulator of protease production and sporulation. | B7HZH8 |
Q7MG90 | GLGB_VIBVY | Glycogen branching enzyme | Vibrio | MFEKLSQAACSEPFAFLGPFIDPTQGALRVWMPGATGVALVLEGQPRIALEREKESAFILKADLNLHLTHYQLAIDWNGIEQLVDDPYQYHGIYAEYDDLHTPKTMYQHMGSQFMTLERDGKSISGIRFLVYAPHATAVSLVGSFNDWDGRRHPMQRLDYGIWGLFIPGLTEGVSYKFEMKGPKGEGLPHKADPWGFYAEQYPSFASVTYDHARYQWQDAQWQTRPVTEKRKEALSFYELHAGSWKRNEQGEFLNYRELAAELVPYLVDMGYTHVELMPVSEHPFYGSWGYQPVGLFAPTSRYGSPDDFKFFVDACHQAG... | Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | Q7MG90 |
Q3JDM3 | ENGB_NITOC | Probable GTP-binding protein EngB | Nitrosococcus | MNSLYRKAHYQGSAYTLSQLPPDEGMEVAFAGRSNVGKSSAINAITGIGGLARTSKTPGRTQMINFFQLDARRYLVDLPGYGYAKVPEAVKRQWQQTLSAYLEQRRALCGIVLVVDIRRLYQPFDLQMLEWCRSRGLPVRILLTKSDKLKRGAANQALQKATTHLQEVFPMARVQLFSAVNHTGIEAIQAQLDEWLGIGG | Necessary for normal cell division and for the maintenance of normal septation. | Q3JDM3 |
A0A455R5H4 | ASCE_ACREG | Ascofuranone/ascochlorin biosynthesis clusters protein E | Acremonium | MTELIPGPKGLPLIGNVLDIDPVDAVVCLGRIADTYGHIYQLKVGGSAKIFISSRELVDELSDESRFTKLVSGPLAQLRNVCHDSLFTAQSDEPAWDLAHKILMPAFGPLAIRGMFDEMHDIASQLVVKWARFGPQDTIDVSGDFTRLTLDAIALCSMSTRFNSFYKQDQHPFVSSMLEVLAESGKRAVRPPFVNDYIFRGSLKHYNTEIATMRRIAMDVLAERRANPMACQKNDLLNAMINGRDPKTGEGLSDESTINNLIVFLIAGHETTSGLLSFLFYYLLTRPDVFEKAQKEVDELVGRGPVTIEHMSKLHYIEAC... | Bifunctional cytochrome P450/NADPH--P450 reductase; part of the asc-1 gene cluster that mediates the biosynthesis both ascochlorin and ascofuranone, a strong inhibitor of cyanide-insensitive alternative oxidases and a promising drug candidate against African trypanosomiasis . The first step in the pathway is performed ... | A0A455R5H4 |
Q2NFW7 | RL14_METST | 50S ribosomal protein L14 | Methanosphaera | MKAITSNVSKSLPIGARLKCIDNTGAREVEIISVKGFKGVRRRLASAGVGDMVVISVKKGTADMRREVTTAVVVRQKKEYRRADGLRVKFEDNAAVIITEDGVLKGSEIRGPIAKEAADLWPAIGSAASIIV | Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome. | Q2NFW7 |
Q8ESL3 | MURQ_OCEIH | N-acetylmuramic acid 6-phosphate lyase | Oceanobacillus | MLDKLPTEQRNPKTMDIDTKSIKEILEMMNREDFTVPQTVQKEISFIEEAVHRTIHSFKSNGRLIYIGAGTSGRLGVLDASECPPTFGVSSEMVKGLISGGLEAITKAKEGAEDSEAMAKQDLLDIKLTEHDTVIGIAASGRTPYVKGALSYANEIGASTVAISNNKNSEIGKIAEIAIEAETGPEVITGSTRLKAGTAQKLILNMISTASMIGVGKVYENLMVDLKPTNKKLVDRSKRIIMEATQVDYTTAENYLQKANNSVKTAIVMILLNCNVDEAIQHLDRAEGFIRKTK | Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. | Q8ESL3 |
Q21MH2 | MRAY_SACD2 | UDP-MurNAc-pentapeptide phosphotransferase | Saccharophagus | MLLWLAEYLQQYISAFAVVKYLTFRAILGVMTALGLSLLLGPWVINKLNKLQIGQSIRDDGPESHLVKSGTPTMGGTLILFAIVFATLLWSDLTNRYVLAVLFVTLSFGLVGWVDDYRKVVQKNSKGLPAKWKYFWQSLAGFTVAYGLYVTAQIPEETTLYIPFFKGVALELGVFYIILTYFMVVGFSNAVNLTDGLDGLAIMPTVMVGSALGIIAYLVGNANFSAYLQIPYVPGAGELVVYCAALAGAGLGFLWFNTYPAQVFMGDVGALALGAALGIIAVIVRHEIVFIIMSGIFVMETVSVILQVASFKLTGRRIFR... | Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I... | Q21MH2 |
O51589 | NANE_BORBU | ManNAc-6-P epimerase | Borreliella | MIIIVKIKRGLIVSCQALENEPLHSSFIMSKMALAAKIGGAIGIRANGVNDISQIKLEVDLPIIGIIKKNYNNCDVFITPTMKEIDELCNEGVDIIALDATFRNRPDGVLLDDFFENIKKKYPKQCLMADISSLDEAINADKLGFDFIGTTLYGYTKNTNGLNIADNDFNFLRTLLNSNLKSTLIVEGKIDTPLKAQKCFEMGVDLVVVGGAITRPAEITKKFVEKINQIKK | Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). | O51589 |
P06729 | CD2_HUMAN | T-cell surface antigen T11/Leu-5 | Homo | MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQV... | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | P06729 |
Q2M3W8 | ZN181_HUMAN | HHZ181 | Homo | MPQVTFNDVAIDFTHEEWGWLSSAQRDLYKDVMVQNYENLVSVAGLSVTKPYVITLLEDGKEPWMMEKKLSKGMIPDWESRWENKELSTKKDNYDEDSPQTVIIEKVVKQSYEFSNSKKNLEYIEKLEGKHGSQVDHFRPAILTSRESPTADSVYKYNIFRSTFHSKSTLSEPQKISAEGNSHKYDILKKNLPKKSVIKNEKVNGGKKLLNSNKSGAAFSQGKSLTLPQTCNREKIYTCSECGKAFGKQSILNRHWRIHTGEKPYECRECGKTFSHGSSLTRHLISHSGEKPYKCIECGKAFSHVSSLTNHQSTHTGEKP... | May be involved in transcriptional regulation. | Q2M3W8 |
Q2NIT8 | GLYA_AYWBP | Serine hydroxymethyltransferase | Candidatus Phytoplasma asteris | MPKNTKRKRLCPKMNQKLGLKDQDQEIFDLIEQEKARQKENILLIASENFVSQAVLDAQGSILTNKYAEGYPQARYYNGCKNVDQIEKIAIQRATKLFGAKYANVQPHSGSQANMGVFQALLKPGDKILGLSLMDGGHLTHGHKLSFSGGFYEAHFYNVNPQTEMLDYDEIRKVALAVKPKLIIAGYSAYSKTINFKKFRQIADEVNAYLIADIAHIAGLVACGLHPCPFEANADVVTSTMHKTLRGPRGGLILTNKEELFKKINRGIFPGIQGGPCIHTIAAKAVAFQEAMMPSFKEYQKQVIKNANTFAKAFQQKGYR... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | Q2NIT8 |
B3DVX0 | RSMH_METI4 | rRNA (cytosine-N(4)-)-methyltransferase RsmH | Methylacidiphilum | MSWKTEEVESHIPVMLKEFLKHCSPKRDEQWIDGTFGYGGHTTALLDKGCKVLALDTDEDAQKRAEILKEKGEEFYFFRKNFSEMAEACFQMGWTAVDGILLDLGVSLGQLKDPKRGFSFQFPDAPLDMRMDRTRERTGAALLNTLSKEQLVQLFSVACNMKESQKLANEIVRFRSTGPIKKVGDFLEIVTRARLLKSKINAATRPFLALRIAVNEELEHLEKALREGTKLLKGGGRIAVISFHSAEDRIVKEFMRSHCLPKKGEGVAEEENHREMFFYKVERVLVSLEERKNNPRSRSARLRIAWKIPLEEKSGL | Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | B3DVX0 |
A0ZZ47 | CEMA_GOSBA | Chloroplast envelope membrane protein | Gossypium | MAKKKAFTPLLYLASIVFLPWWISLSFNKSLKSWITNWWDTRQSETFLNDIQEKSILEQFIEVEELFLLDEMIKEYPETHLQKLRIGIQKETIQLIKLHNEDHIHTILHFSTNLICFVILSGYSILGNEELLILNSWAQEFLYNLSDTIKAFSILLLTDLCIGFHSPHGWELMIGSIYKDFGFTHNDQIISGLVSTFPVILDTIFKYWIFRYLNRVSPSLVVIYHSMND | May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts. | A0ZZ47 |
Q7Z6Z6 | PLPL5_HUMAN | GS2-like protein | Homo | MGFLEEEGRWNLSFSGAGYLGAHHVGATECLRQRAPRLLQGARRIYGSSSGALNAVSIVCGKSVDFCCSHLLGMVGQLERLSLSILHPAYAPIEHVKQQLQDALPPDAHVLASQRLGISLTRWPDGRNFLVTDFATCDELIQALVCTLYFPFYCGLIPPEFRGERYIDGALSNNLPFADCPSTITVSPFHGTVDICPQSTSPNLHELNVFNFSFQISTENFFLGLICLIPPSLEVVADNCRQGYLDALRFLERRGLTKEPVLWTLVSKEPPAPADGNWDAGCDQRWKGGLSLNWKVPHVQVKDVPNFEQLSPELEAALKK... | Has abundant triacylglycerol lipase activity. | Q7Z6Z6 |
D9I2G3 | NL1A2_RAT | NACHT, LRR and PYD domains-containing protein 1a, N-terminus | Rattus | MEESQSKQESNTRVAQHGSQQDVDPTFQTKRALEKERSKPRPRPLPRVQLQSLPGWSSTSKDVPLSQLIREMDHESRRCIHRSKKKLDRSEHISQGTIPEIYEKRKETISHTQSMEQKYLFQNFTKLLLLQKCCPGGSEKLVRESWHPCVPEEGGHMIEIQDLFDPNLDTEKKPQLVIIEGAAGIGKSTLARQVKRAWDEGQLYRDRFQHVFFFSCRELAQCKQLSLAELIAQGQEVPTAPTRQILSRPEKLLFILDGIDEPAWVLEDQNPELCVHWSQAQPVHTLLGSLLGKSILPEASLMLTARTTALQKLVPSLGQP... | Constitutes the active part of the Nlrp1a inflammasome. In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, ... | D9I2G3 |
A0KUJ9 | DER_SHESA | GTP-binding protein EngA | Shewanella | MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLSIAQHLRSRQKTTFVVANKIDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYALTPYAEAMGIERQGEEEEVDERQYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYIPMERDGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLGLLGFALNAGRALVIAVNKWD... | GTPase that plays an essential role in the late steps of ribosome biogenesis. | A0KUJ9 |
P39687 | AN32A_HUMAN | Putative HLA-DR-associated protein I | Homo | MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD | (Microbial infection) Plays an essential role in influenza A, B and C viral genome replication . Mechanistically, mediates the assembly of the viral replicase asymmetric dimers composed of PB1, PB2 and PA via its N-terminal region . Also plays an essential role in foamy virus mRNA export from the nucleus . | P39687 |
A4WWA0 | UPPP_CERS5 | Undecaprenyl pyrophosphate phosphatase | Cereibacter | MTDSTTLVALVLGLLEGLTEFIPVSSTGHLLLAGHFLGFESAGRSFEVVIQLGAVLAVLTVYASKLISVIRAAPRDPQAARFLAAVLLAFLPAVVVGVMAHGFIKTVLFETPILIAIMLILGGIILLFVDRMAPAPRYNDVTEVPLGVALKIGFFQCLAMVPGVSRSGATIVGALLLGTGKRAAAEFSFFLSMPTMAGAFAFDLYKNRDVLDAGALGEIAVGFVAAFLAAVLVVRWLLGYVSRHGYSLFGWWRIIVGSIALAALLKGF | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin. | A4WWA0 |
Q8CGZ0 | CHERP_MOUSE | SR-related CTD-associated factor 6 | Mus | MEMPMPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQAPELEPTSAMPPLPQPPLAPTASLTPAQGTPSMDELIQQSQWSLQQQEQHLLALRQEQVTTAVAHAVEQQMQKLLEETQLDMSEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQSLKTQ... | Involved in calcium homeostasis, growth and proliferation. | Q8CGZ0 |
C5D2K6 | MASZ_GEOSW | Malate synthase G | unclassified Geobacillus | MGEYVKVGNLQVAKLFYEFMNDEVLPGSEVNKEKFWKDFETLIADLTPKNKALLARRDELQAKINEWHKEHRGNFDMEKYKAFLTDIGYLEPEVDDFEITTEGVDEEIAVQAGPQLVVPLTNARYALNAANARWGSLYDALYGTDAISEEDGAERGDSYNPVRGAKVIAYAREFLDQAVPLKEYSHKDAVQYAVVDGKLVVSVEGGSTTTLKEEEKFIGFQGNPENPTAILLKNNGLHIEIQIDRNHPVGKTDKAGVKDIYLEAAVTTIMDGEDSVAAVDAEDKVLVYRNLLGLVKGDLTSTFTKGGKTITRALNPDRVY... | Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA. | C5D2K6 |
Q2RLY7 | FABZ_MOOTA | Beta-hydroxyacyl-ACP dehydratase | Moorella | MDWNAIQGILPHRYPFLLVDRVLEVEAGRRAVGQKNVSGNEWYFSGHFPGQPVMPGVLIMEALAQVGAVALLSLPEFQGRLALFGGMDRVRFRRQVVPGDVLRLETEIIKLKGRVGKGYGRAFVGEELAAEGELLFAVGEKIE | Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Q2RLY7 |
A7FUK9 | MUTL_CLOB1 | DNA mismatch repair protein MutL | Clostridium | MRKINLLDLETTNKIAAGEVIERPFSVVKELVENSIDAGAKNITIEIEDGGQKLIKIIDDGEGIYPIDIKNAFLPHATSKINSIEDIYKISTMGFRGEALASISSVSKTKLKSRVDSYNFGKEIYIEGGKIEYLKDTGCNVGTTIEVSDLFYNVPARLKFLKSARSDSSSISDIVNRFILSHPDISFNLINKGKQSIKSYGTGNLKDSIRCVYNKTISENLINFESHKDIISVYGFIGKPEISRKSRTNQSIFVNKRYVKSKFITAAVENAFKSFLTVNSYPFFVIFIDIFPEYIDVNVHPTKSEVKFKDERAMFKTIFD... | This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ... | A7FUK9 |
B6JGN8 | BIOD_AFIC5 | Dethiobiotin synthase | Afipia | MSTRLVVSGTDTDVGKTVFSAALAGALDADYWKPVQAGRDDGTDALRVARLSGLPPERILPERYILNTPASPHYAARIDGITIDTNDLTPPPAKDRPLVIEGAGGLMVPINEDTLFIDVFARWKLPLVLCARTTLGTINHSLLSIEAVKRRDIPLVGIAFIGEDYAESERIICKIGGVRHLGRLPPLSPLTPEALRAAFITSFNLSDFTA | Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring. | B6JGN8 |
A6VZL5 | PRMA_MARMS | Ribosomal protein L11 methyltransferase | Marinomonas | MPWLQIRINTTPDHVPAFEDTLLDCGAMVVTFEDVHDDPVYEPDLNTTPLWKNTKVTGLFEADADIEHIRPVIEHKAESLGETDIDMKIEIVEDKDWEREWMDNYHPIQFGERLWVCPSWREVPDPNAVTLMLDPGLAFGTGTHPTTALCLQWLDSIDCKDKTIIDYGCGSGILGIAGLLLGANNMVGIDIDPQAVQATEANAERNKIDPSRLEVKLPPYESDLQADIVVANILAGPLAHLAPTISALVKNQGQLALSGILANQAQEVIEAYQEWFTIDSITEKEEWVRIVGTKHA | Methylates ribosomal protein L11. | A6VZL5 |
O19872 | RBL_BIXOR | Ribulose bisphosphate carboxylase large chain | Bixa | FVGFKAGVKEYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTAVWTDGLTSLDRYKGRCYHIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAG... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. | O19872 |
B8FES0 | RL6_DESAL | 50S ribosomal protein L6 | Desulfatibacillum | MSRVGKKPIPIPAKTKVTVSNGTVTVQGEKGKLERPLHPDVELKIEGDEITVVPVVERRKITAVQGLVRSLVANMVTGVSTGFKRVLEVNGIGYKAELNGQTLNLTLGFSHPVDFPLPQGITAEVDKKNNITLEGIDNELLGQTAASIRALRPPEPYKGKGIKYAEERIIRKAGKTGA | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | B8FES0 |
A0A0A6YYK4 | TVB71_HUMAN | Probable non-functional T cell receptor beta variable 7-1 | Homo | MGTRLLCWAAICLLGADHTGAGVSQSLRHKVAKKGKDVALRYDPISGHNALYWYRQSLGQGLEFPIYFQGKDAADKSGLPRDRFSAQRSEGSISTLKFQRTQQGDLAVYLCASSS | Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain . Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or ... | A0A0A6YYK4 |
Q8TV85 | METK_METKA | Methionine adenosyltransferase | Methanopyrus | MVRNIVVETMKRSPFTETEVEIVERKGVGHPDSLADGIAESVSRALCREYIERFGRILHHNTDEVQIVAGESRPEFGGGEVIRPIYILVTGRATAYVGDEEIPVGTIALEAATEYLEETVRHLDTEKHVVIEPKIGHGSADLRDVFERGEEVPLANDTSFGVGYAPLTTTERLVYETERKINSPKLKKDLPEVGEDVKVMALREDNKIELTVAAAMVSQRIDDIDHYISVVEELRDRVADLAAEIASDHDVEVHVNTADDYERESVYLTVTGTSAEQGDDGSVGRGNRVNGLITPFRPMSMEAAAGKNPVNHVGKLYNVL... | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Q8TV85 |
Q0KCA7 | ACCA_CUPNH | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Cupriavidus | MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEISRLAGKSQQLTKDIYANLTPWQVAQIARHPQRPYTLDYVREIFTDFHELHGDRTFADDLSIIGGLARFNGQACMVIGHQKGRDTKERAMRNFGMPKPEGYRKAKRLMELADKFGLPIFTFVDTPGAFPGIDAEERGQSEAIGHNLYVMAGLKVPLIATIIGEGGSGGALAIAVGDVVQMLQFATYAVISPEGCASILWKTAEKAPEAAEALGLTAHRLKALGLIDKIVSEPLGGAHRDYKGMAAMLKRSLAESLRQFQGMSVKELQARRYERLLAYGKFKETG... | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Q0KCA7 |
Q9SGE2 | SMR2_ARATH | Protein SIAMESE-RELATED 2 | Arabidopsis | MSKLLETLEEEKTVEQKPRSQEEEDHQDSSKKEELLESLCTPTSSDHKIPEVETCPPPPRKRPREISLTKKTRLSKDLRFFEATDVGSQEVETLFVHEPNHVRKKRRSNSA | Cyclin-dependent protein kinase (CDK) inhibitor that restricts cell proliferation and cooperates with SIM and SMR1 to promote endoreplication during leaf development . | Q9SGE2 |
C3PFW7 | ILVD_CORA7 | Dihydroxy-acid dehydratase | Corynebacterium | MYPLRSKVTTVGRQASGARALWRATGSKESDFGKPIVAIANSFTQFVPGHVHLKNVGDIVADAVREAGGVPKEFNTIAVDDGIAMGHSGMLYSLPSREIISDSIEYMVNAHTADALVCISNCDKITPGMLNAALRLNIPTIFVSGGPMEAGKAVVVDGVAHAPTDLITAITASASDAVSDEGLTRVEESACPTCGSCSGMFTANSMNCLTEALGLALPGNGTTLATHSARRDLFEQAGRTIVDLCRRYYGEEDDAVLPRSIATKEAFSNAMALDMAMGGSTNTILHTLAAAQEGEVDFTLEDINEISYRVPCLSKVAPNG... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | C3PFW7 |
Q82T68 | RS12_NITEU | 30S ribosomal protein S12 | Nitrosomonas | MPTISQLVRKPRKAKRTKSKVPALESCPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGYEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTAGVKDRKQARSKYGSKRPKSA | Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com... | Q82T68 |
A4SE77 | SYM_CHLPM | Methionyl-tRNA synthetase | Chlorobium | MPQFQRTLVTTALPYANGPVHLGHLAGVYLPADLFVRYKRLQGEDVIHIGGSDEHGVPITITAEKEGITPRDVVDRYHSMNLEAFKRCGISFDYYGRTSSELHHKTAQEFFLEIEGKGIFERKTEKLFYDASACRFLSDRYVTGTCPICGNTEANGDQCEQCGTHLSPLELINPKSKLSDATPELRETLHWYFPLGRFQKQLEAFVGSHDDDWRANVLNYTRTWLNQGLNDRAITRDLSWGIKVPLQDPEAEGKVLYVWFDAVLGYVSFAREWAVLQGSPDRWKEYWQNPDSRVVNFIGKDNVVFHTLMLPAILMAWNEG... | Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | A4SE77 |
P35145 | RPSF_PRIMG | Stage II sporulation protein AC | Priestia | MDVEVKKNKNEPYLKDHEVKDLIKRSQQGDQIARDTIVQKNMRLVWSVVQRFINRGYEPDDLFQIGCIGLLKSVDKFDLSYDVKFSTYAVPMIIGEIQRFIRDDGTVKVSRSLKEMSNKIRKAKDELSKLLGRVPTVAEVAEHLDLTPEEVVLAQEANRAPSSIHETVYENDGDPITLLDQIADHTEAKWFDKIALKEAIEELDEREKLIVYLRYYKDQTQSEVAARLGISQVQVSRLEKKILKQMKLHMNDT | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. It is responsible for directing gene expression in the forespore compartment of developing cells of Ba... | P35145 |
Q8XKI3 | THII_CLOPE | tRNA 4-thiouridine synthase | Clostridium | MNNLILVKYASEIFLKGLNKNKFERKLKENIRKKLKDIDHEFITDQNRWFIKSEDLDGVIERVKKVFGVKELCLVTQVTGDFDSIKEEGLKKIKESKAKSFKVETNRANKKFPMNSMEVSRAVGGYILSELGDEIEVDIHNPECKLYVEIRGNAYVFTDKDKIKAVGGLPYGMNGSTMVMLSGGIDSPVAAYLMARRGVETHCVYYHSHPYTSERAKDKVKELAKIVGRYTEKITLYVVPFTEIQMDIIEKCREDELTIIMRRFMMRVACELSEKKKIQSITTGESIGQVASQTMEGLIVSNDASDRPVFRPLIAMDKED... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | Q8XKI3 |
Q8DM28 | RL11_THEVB | 50S ribosomal protein L11 | Thermosynechococcus | MAKKVVAVIKLAIQAGKANPAPPIGPALGQHGVNIMMFCKEYNARTADQVGMVVPVEISVYEDRSFTFVLKTPPASVLIQKAAGIEKGSGEPNKKKVGSITRAQLREIAEKKMPDLNANDIEAAMRIIEGTARNMGVTITD | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | Q8DM28 |
A0PQ65 | RIMM_MYCUA | Ribosome maturation factor RimM | Mycobacterium | MELVIGRVVKAHGITGEVVVEIRTDEPDRRFTPGASLRAKRSRDGGTGRNYVIEGVREHGARLLVRLAGVNDRDTADGLRGSLFVIDSADLPPIEEPDTYYDHQLEGLRVRTTAGQDVGVVAEVLHTGAGELLAVKCDSGEVLVPFVGAIVTSVSLDDRILEIDPPDGLLDLGS | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | A0PQ65 |
A9L340 | MDH_SHEB9 | Malate dehydrogenase | Shewanella | MKVAVLGAAGGIGQALALLLKTQLPAGSHLSLYDIAPVTPGVAVDLSHIPTAVEIKGFAGEDPTPALVGADVVLISAGVARKPGMDRSDLFNINAGIVRNLIEKVAATCPTALVGIITNPVNTTVAIAAEVMKKAGVYDKNRLFGITTLDVIRSETFIAELKSLNVADVKVNVIGGHSGVTILPLLSQVEGVTFTDEEVASLTTRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEANIVECAYVDGGSEHAEFFAQPVLLGKNGIEKVLPYGEVSAFEANARDSMLDTLKGDIKLGVDFVK | Catalyzes the reversible oxidation of malate to oxaloacetate. | A9L340 |
Q15293 | RCN1_HUMAN | Reticulocalbin-1 | Homo | MARGGRGRRLGLALGLLLALVLAPRVLRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLTPDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILENWNMFVGSQATNY... | May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. | Q15293 |
O65796 | HEM13_HORVU | Glutamyl-tRNA reductase 3, chloroplastic | Hordeum | MASTSTASATAMAGAFAAAGVNKPRGSAACPRVPAGGRQRLSCVVRCDAGPGVPAQMAAMAASVAALEQFKISADRYMKEKSSIAVIGLSIHTAPVEMREKLAVAEELWPRAVAELTNLNHIEKAAVLSPCNRMEIYVVALSWNRGIREIVDWMSMKSGIPAVELREHLFMFRDSDATRHLFEVSSGLDSLVLGEGQILAQVKQVVRSGQNSGGLGKNIDRMFKDAITAGKRVRSETNISCGAVSVSSAAVELALMKLPKSECLSARMLLIGAGKMGRLVAKHLAAKGCKKVVIVNRSVERVDAIREEMQGIEIVYRSLT... | Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | O65796 |
D2H163 | NTM1A_AILME | N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed | Ailuropoda | MTSEVIEDEKQFYLKAKTYWKEVPPTVDGMLGGYGHISSIDISSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFGVVDMVDVTEDFLIKARTYLGEEGKRVRNYFCCGLQDFSPEPNSYDVIWIQWVIGHLTDQHLAEFLRRCKQGLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLDVVHRIVRSAGLSLLAEERQENLPDEIYHVYSLALR | Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-... | D2H163 |
Q2FPX3 | DTDA_METHJ | D-tyrosyl-tRNA(Tyr) deacylase | Methanospirillum | MTPKEQSPTTLLISSRKDPAGSLIHEELYSFLEDDKRAHSHIRHWHAEERLIYLDGPSLPHDADRILFLSRHASERPRPVLTVHVTGNFGSADYGGRPNTLTPAATGLMHALINRLIIHAPEGYEVMYEATHHGPTDIPLPSCFIELGSTEKEWNDRIAARAVAQAVLDALLMDTSSVIPLAGFGGTHYAQRQTEITKLTRGGFGHIMPTRDIPHLTDALFQDIISSTGAFAIYIDGKSMSGKEERMITGLADKHTIPILGQGDLMRLFDLPFSEYMSIRNLAESLIPGSSIVLHTILEMPAPVSLTIPGELVDEVMKVA... | D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. | Q2FPX3 |
Q7SYL1 | AR2BP_DANRE | ADP-ribosylation factor-like protein 2-binding protein | Danio | MVDMQSLDEEDFSVSKSSDADAEFDIVIGNIEDIIMEDEFQHLQQSFMEKYYLEFDDSEENKLSYTPIFNEYIEILEKHLEQQLVERIPGFNMDAFTHSLKQHKDEVSGDILDMLLTFTDFMAFKEMFTDYRAEKEGRGLDLSTGLVVKSLNSSSASPLTPSMASQSI | Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2. | Q7SYL1 |
Q2W3I0 | CLPX_MAGSA | ATP-dependent Clp protease ATP-binding subunit ClpX | Magnetospirillum | MTKSTSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVRSRDGVPTPKDICQVLDDYVIGQSHAKKVLSVAVHNHYKRLQHGGKNNEVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAAEYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIIGSRGRGTSIGFGADVRGPDERRTGEILREVEPEDLLKFGLIPEFVGRLPVLATLEDLDVDALI... | ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Q2W3I0 |
B0K897 | LGT_THEP3 | Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase | Thermoanaerobacter | MYIPTISPYAFKIGPIDVHWYGIFMAISIAIGGYYLYRQAMKLNYDEDFLLNLLMIVVISGVVGARLMFVLANYPEWFIKDPVQVLKIYEGGLSWHGAVLGGFLAGLYYCRKKGVRINPLEDFAVLGLSIGNILVRIGNIFNQEVLGRPTEFAFGRWPAQLVGVAMGIILLIRYFYIQKKHMPDGYQFWSFIFYYQLMRGLIEETVRDNPLIWPVYLNEKWGIGFFTLTQLVTPFILILAYWMIRRVLNDPNKQFYN | Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | B0K897 |
Q55C52 | GTPB3_DICDI | GTP-binding protein 3 | Dictyostelium | MIKRLFCSINKNKIINEPPKLSIIKDTIYNLSSGVGKSGVAIIRVSGPQAETVIRKLIKKSDVDKNEEIKSRYATLSTFYNPKTNEQLDKGMFIWFPSPNSFTGEDVVEFHIHGGRAVIYETMEAIGLIEGTRPSEQGEFTKRAFENGKMDLTQVEGLSDLLDASTSFQKKIALKQMQGSISEFYLSLRKDLIRASAYMEAFIDFGDDAELDPEIVDQSRNRIISIRDKIQQHLNDGKRGERLRDGANIAIVGPPNAGKSSLINLLTNRKASIVSPIAGTTRDIVEVILDIDGYPVIIGDTAGLRNSTNDQIEIEGIEMA... | GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. | Q55C52 |
Q20WM1 | RS20_RHOPB | 30S ribosomal protein S20 | Rhodopseudomonas | MANTTSAKKATRKIARRTIVNKSRRTQMRGAVRIVEEAIASGDRDAALKAMIRAEPELMQAAQRNIVHKNTASRKVSRLSHQIAKLAK | Binds directly to 16S ribosomal RNA. | Q20WM1 |
Q08215 | PEX15_YEAST | Peroxisome biosynthesis protein PAS21 | Saccharomyces | MAASEIMNNLPMHSLDSSLRDLLNDDLFIESDESTKSVNDQRSEVFQECVNLFIKRDIKDCLEKMSEVGFIDITVFKSNPMILDLFVSACDIMPSFTKLGLTLQSEILNIFTLDTPQCIETRKIILGDLSKLLVINKFFRCCIKVIQFNLTDHTEQEEKTLELESIMSDFIFVYITKMRTTIDVVGLQELIEIFIFQVKVKLHHKKPSPNMYWALCKTLPKLSPTLKGLYLSKDVSIEDAILNSIDNKIQKDKAKSKGKQRGVKQKIHHFHEPMLHNSSEEQVKVEDAFNQRTSTDSRLQSTGTAPRKKNNDITVLAGSF... | Essential for the biogenesis of peroxisomes. Has a role in anchoring PEX6 onto the peroxisomal membrane. | Q08215 |
Q31D68 | RBFA_PROM9 | Ribosome-binding factor A | Prochlorococcus | MPNNFRLAKVSSLLKKEITLILQNDLENDLIRDYFVNISKIDLSGDLQHCKIYITSTAKETVRKEIVANLNTAKSFIRNNLGKRIEMRRVPEIIFKEDIVLDKGLSVLKLLDELKNKHQDKNYEDKDANS | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | Q31D68 |
P11862 | GAS2_MOUSE | Growth arrest-specific protein 2 | Mus | MMCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAATVQEKFKESMDANKPAKTLPLKKIPCKASAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPTKFCVERLSQGRYRVGEKILFIRMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPVQSKSPTLKDMNPDNYLVVSATYKAKKEIK | May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May play a role in chondrocyte proliferation and differentiation, and in limb m... | P11862 |
P05504 | ATP6_RAT | F-ATPase protein 6 | Rattus | MNENLFASFITPTMMGLPIVVTIIMFPSILFPSSERLISNRLHSFQHWLIKLIIKQMMLIHTPKGRTWALMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMNLSMAIPLWAGAVILGFRHKLKNSLAHFLPQGTPISLIPMLIIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLMDISPPTATITFIILLLLTVLEFAVALIQAYVFTLLVSLYLHDNT | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous ca... | P05504 |
Q9NQE7 | TSSP_HUMAN | Serine protease 16 | Homo | MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVGWLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWICFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECRAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDGQTGAPLSVRQLCGLLLGGGG... | Protease that may play a role in T-cell development. | Q9NQE7 |
Q55DE2 | SDA1_DICDI | SDA1 domain-containing protein 1 homolog | Dictyostelium | MGTRILDLLQLQNLTKRDPSAYKEEFLLQYQHYLTQLQIFQLKPTKEFKHFSQLVSYLSHVCVCYPKELSEFPKQISDLLENNCNNLEPELRRILAKSLILMRNRNLLPQIQMLSLFFKLFRVHDKPLRSLLYSHIVADIKNTNLKQKNQKLNRTLQNFMFTMMNDDSEIASKMSLKVMIELFRKKIWHDTKTVNVISNGVFSKNSKILITTLNFFLHIDNPDKPDEEEEDEAVKEKRAKDNFRKKSLAHRVGKKTKGRITRLAKSKVDLKKAKQEEDNKLQPNFPAIELIHDPQGYCDKLFNVLVKTTEKFETRIMIMN... | Required for 60S pre-ribosomal subunits export to the cytoplasm. | Q55DE2 |
A5EX94 | RPOA_DICNV | Transcriptase subunit alpha | Dichelobacter | MALTELLTPRIVQIKEIGSNTSRVTLEPLERGFGYTLGTALRRVLLSSIEGAAITECQIDGVSHEYSAIEGVKEDVIDVLLNLKNIALLMPDLERAEIRLSVTEKGAITAGDFELPAGVEIVNPDCVIAHLTRDIPFSLTAVVEKGRGYRVAPQADDNSESTRSNVLRLDASFSPVRRIAYRVEQARVEQRTDLDKLIIEIESNGTIDPEQAIRDAATILHNQIKVFVDLESTEEETEEEEEIYIDPVLLRPVDDLELTVRSANCLKAENINNIGDLVRRTEVELLKTPNLGKKSLNEIKEVLAAHNLELGMDIENWPQN | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | A5EX94 |
A7X4L6 | REX_STAA1 | Redox-sensing transcriptional repressor Rex | Staphylococcus | MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQIDSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTYNFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQKVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE | Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | A7X4L6 |
Q1NEI6 | KDRDH_SPHSS | L-KDR 4-dehydrogenase | Sphingomonas | MSVFAGRYAGRCAIVTGGASGLGKQVAARIIAEGGAVALWDLNGDALAATQAEIDATHVVALDVSDHAAVAAAAKDSAAALGKVDILICSAGITGATVPVWEFPVDSFQRVIDINLNGLFYCNREVVPFMLENGYGRIVNLASVAGKEGNPNASAYSASKAGVIGFTKSLGKELAGKGVIANALTPATFESPILDQLPQSQVDYMRSKIPMGRLGLVEESAAMVCFMASEECSFTTASTFDTSGGRTTF | Catalyzes the NAD(+)-dependent dehydrogenation of 2-dehydro-3-deoxy-L-rhamnonate to form 2,4-didehydro-3-deoxy-L-rhamnonate. Does not show any detectable activity in the presence of NADP(+). | Q1NEI6 |
O31620 | THID_BACSU | Hydroxymethylpyrimidine phosphate kinase | Bacillus | MSIYKALTIAGSDSGGGAGIQADIKTFQELDVFGMSAITAVTAQNTLGVHGVHPLTVETLRQQIDAVAEDLRPDAVKTGMLWNADMIEEVARKIDEYGFNRVIVDPVMIAKGGASLLRDESVATLKELLIPRSYAITPNVPEAETLTGMTISSLDDRKKAAEQLVKMGAQHVIIKGGHQPEDNHITDLLFDGSMFMQITHPYINTKHTHGTGCTFAAALTAQTAKGDSIHQAFEVAANFVREAVENTLGIGSGHGPTNHFAFKRNSLNTSR | Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. Shows no activity with pyridoxal, pyridoxamine or pyridoxine. | O31620 |
P26153 | ACHB4_CHICK | Neuronal acetylcholine receptor non-alpha-3 chain | Gallus | STAADAEEKLMNHLLSPDRYNKLIRPAVNSSQLVSIELQVSLAQLISVNEREQIMTTNVWLNQEWIDYRLAWKPSDYEGINMLRIPAKHIWLPDIVLYNNADGTYEVSLYTNAIVQNNGSIRWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDMVLKTSMASMDDFTPSGEWDIVALPGRRTENPLDPNYVDVTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKLVFLER... | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | P26153 |
A6US81 | DPHB_METVS | Diphthamide biosynthesis methyltransferase | Methanococcus | MLVMAGLGLYDELDVTLKTVEFAKKVDKIYAEFYTAILTGTTIEKIEKTLQKEITVLNREKVEYETNKLIEEAKEKDIMFLTAGDPMVATTHVDIAVEARKKGIEVIILNAPSIYSAIGITGLQLYKFGKTTSIVFPEPNYFPETPYDVIKDNLSLGYHTLCLLDIQTDKQKFMTANEGLSVLLEIEEKRKEKIIDENTKVLVVARAGSIKPGLFYGKIKDLIKHDFGTPLHCVIILGKLHFMETDALKYLFENI | S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosy... | A6US81 |
Q63AN4 | UPPP4_BACCZ | Undecaprenyl pyrophosphate phosphatase 4 | Bacillus cereus group | MNWLEAFILGIIQGLTEFLPISSTGHLYLGRHLFQLDEAGLFLDTMLHIGTLLAVFIYYKKEFIYLIKNPFSKLMLLLIVGTIPAVVIGLLFKDFFEDISKTGITIGWEFLVTGFFLYMADKQKNGRKKMDDITYKDAFIIGSFQAAAIFPAISRSGMTIVAALWRKLDRETAAYFSFLLSTPAIVGAIILQFVDVFQGKAESISSTSLIVGTLSAAFFGYIAVSWMIQYLKRHSLKVFAYYVWGLGILILTLQFTDVF | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin. | Q63AN4 |
Q0W1W8 | RS5_METAR | 30S ribosomal protein S5 | Methanocella | MAAPYQREQAAWIPKTRLGKMVAEGKITTMEEAFETGLPIKEYQIVDALLPDLVDEVLDISMVQRMTDSGRRVKFRTTVVVGNGNGYVGLAQGKGVQVGPAIRKAIENAKLNIIKVARGCGSWECGCGLTHTVPSQVEGRAGSLKVVLMPAPRGLGLAAGGPAKKVLEMAGYKDVWSRTEGETRTTINFALATYKALESTTTVRTRQKEEAQ | With S4 and S12 plays an important role in translational accuracy. | Q0W1W8 |
P10092 | CALCB_HUMAN | Calcitonin gene-related peptide II | Homo | MGFRKFSPFLALSILVLYQAGSLQAAPFRSALESSPDPATLSKEDARLLLAALVQDYVQMKASELKQEQETQGSSSAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAFGRRRRDLQA | CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. | P10092 |
Q9PBX0 | RPIA_XYLFA | Phosphoriboisomerase A | Xylella | MSEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGRTPKRIKGAVSSSEQSTAHLKQHGIEVLELNHTGTLPLYVDGADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQVATLGKLPLPIEVIPMARSLVARQIMARTDGQPVWREGVITDNGNVILDVHHLRITDPVKLEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | Q9PBX0 |
Q4KFV3 | PYRF_PSEF5 | OMP decarboxylase | Pseudomonas | MSACQTPIIVALDFPTRDAALKLADQLDPKLCRVKVGKELFTSCAAEIVGTLRDKGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLDQRSGPKPLLIGVTVLTSMEREDLAGIGLDIEPQEQVLRLAALAQKAGMDGLVCSALEAQALKSAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALADVVAELAL | Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Q4KFV3 |
Q17ZL6 | PAND_HELAH | Aspartate 1-decarboxylase alpha chain | Helicobacter | MTFEMLYSKIHRATITDANLNYVGSITIDENLAKLAKLREGMKVEIVNINNGERFSTYVILGKKRGEICVNGAAARKVAIGDVVIILAYASMNEDEMNVHKPCIVLVNEKNEILEK | Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | Q17ZL6 |
Q8Y7G4 | DXR_LISMO | 2-C-methyl-D-erythritol 4-phosphate synthase | Listeria | MKKIILLGATGSIGTQTLAIIRENPEKFQVVALSFGRNMERGRAIIKEFKPKMVAVWHTRDRVTLEAEFPNVKFFNGLEGLREVATYLDGDVLLNAVMGSVGLLPTLDAIEAGKAIAIANKETLVTAGHLVMRAAKEKNISLLPVDSEHSAILQALNGENTERIEKIILTASGGSFRDKTREQLSAVTVKEALKHPNWNMGNKLTIDSATMFNKGLEVMEAHWLFGVDYDDIEVVIQRESIIHSMVQFVDGSFIAQLGTPDMRMPIQYALTYPDRLYIPYEKEFRITDFSALHFEKVDYERFPALKLAYNAGKIGGTMPT... | Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | Q8Y7G4 |
A4XYE4 | TPIS_PSEMY | Triose-phosphate isomerase | Pseudomonas | MRRPLVAGNWKMHGTRASVAELIEGLRRQELPVEVDVAVFPSSLHVTQVVEGLAGKAVKVGAQDCAAQVEQGALTGELAVSQLVDGGCELVLVGHSERRLILGESDEVVVSKFAAVQKAGLTPVLCVGETREQREANATLGVVGGQLAAVIDALGVQALNNAVVAYEPVWAIGTGLTATPEQAQEVHAAIRAQVAQLDAQVASELRILYGGSVKAASAAELFGMQDIDGGLVGGASLNADEFGAICRAAGN | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). | A4XYE4 |
A8MLD3 | RPOC_ALKOO | Transcriptase subunit beta' | Alkaliphilus | MYELNNFESIKIALASPEKIRQWSKGEVKKPETINYRTLKPEKEGLFCEKIFGPTKDWECHCGKYKRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRSLEKVLYFAAYIVIDPGETGLTEKQVLTEKEYSEAIEKYGSGSFKAGMGAESVKKLLENIDLEELYKDLRSKLKESTGQKRIRTIRRLEVVDAFKHSGNKPEWMILDVIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGKPVTGPGNRPLKSLSDM... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | A8MLD3 |
Q3KMU7 | RECF_CHLTA | DNA replication and repair protein RecF | Chlamydia | MRVLSLFLKDFRNYTDLRLELGPEMNSIFGLNAQGKTNLLEALYILSLGRSFRTSRLTDAIRFGASHFFIEAVFSHKEVFHTLSIQVDKKGKKILFDGAPITKLSELVGLFPVILFSIKDIAIIEGSPSERRRFLDLLLAQASDKYTEHISLYHKALDQRNASIKAQNQKAISAWNSPLIAYGSLVAFLRNECTKKLNTIFQTLWDNTLKETLSLRYESSLITEESPTLNDIASNYYEQLRIANTKDLDLGYTMVGPHRDELLLTINDLPVAKFSSEGQKHSLLAVLRFAECVYLQEEFCIHPILCMDDIHACLDQQRLD... | The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | Q3KMU7 |
A4Y879 | TRUA_SHEPC | tRNA-uridine isomerase I | Shewanella | MRIALGIEYDGSGYFGWQRQAEVDSVQGQLERALSIVANEPIGLFCAGRTDAGVHATGQVVHFDTNAIRNEGAWTLGVNANLPDNIAVRWVKEVDDSFHARFSATARRYRYVIYNHSFRPGILRHGVSHYHGNIDADKMHQAAQVLLGEQDFTSFRAVQCQSKTPFRNVHCVNVTRQGMYVIVDIAANAFLHHMVRNIVGSLLEIGLGNQPLTWMGDLLALKDRNQAAATAKPHGLYLVDVTYPEQYQLPKLALGPLFMLD | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | A4Y879 |
Q47LJ8 | RL22_THEFY | 50S ribosomal protein L22 | Thermobifida | MGTRAQARFVRVTPRKARRVVDLIRGLPAEEAQAVLRFAPQAASGPVGKVLASAIANAEHNDKLDRETLVVSRAWVDEGPTLKRIRPRGFGRAFRVNKRTSHITVEVAPRDTVGAASAKRKERTR | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | Q47LJ8 |
Q9KCB3 | TRPD_HALH5 | Anthranilate phosphoribosyltransferase | Halalkalibacterium (ex Joshi et al. 2022) | MFKETLRECMEGHTLAERKAEQVMDAIMKGEATASQIASLLTVLRFRGETVAEMTGFARAMRRHSIQIEHSFSQVVDTCGTGGDDVGTFNISTATALLVSALGVPVAKHGNRAVSSKSGSADVLEALQIPIQSSPEEATASLQKHNMCFMFAPLYHVAMKHAVAPRKEIGFRTIFNLLGPLTNPARAEHQLIGVYDRNFAEKMAETLRRLGTKHSLLVAGHGGLDELSITGPSTVFEVKGDAIDRYELIPEDVGLERGDLAQIQVSTVQESATLIDQVLIGKANKSAQQIVLLNAGAALYAADRVDSIKAGVALAKEGIA... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | Q9KCB3 |
Q5NN91 | PLSY_ZYMMO | Lysophosphatidic acid synthase | Zymomonas | MSLEMIAVLIFTMGYLLGSVPFGLILARLFGSVDVRQVGSGNIGATNVLRTGRKDLAALTLFFDIGKGALAVLLAHGFSYHLYQQTGCAPDLTLIAGAAAFLGHCYPVWLGFRGGKGVATMLGVSFAAWWVAGVVFAVAWLLSAKISRYSSVGGMVGAIAATISVMFMPASHEIHQVYIALFSGMTILLLWRHRGNIKRLLSGQESRIGDPQ | Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | Q5NN91 |
P61581 | NP24_HUMAN | HERV-K_22q11.21 provirus Np9 protein | Homo | MNPSEMQRKGPPRRWCLQVYPTAPKRQRPSRTGHDDDGGFVEKKRGKCGEKQERSDCYCVCVERSRHRRLHFVMC | May possess a function in tumorigenesis. | P61581 |
A8FGH7 | METK_BACP2 | Methionine adenosyltransferase | null | MSQNRRLFTSESVTEGHPDKICDQISDSILDEILKKDPNARVACETSVTTGLVLVSGEITTSTYVDIPKTVRDTIKEIGYTRAKYGFDAETCAVLTSIDEQSADIAQGVDKALEAREGTMTEEELDAIGAGDQGLMFGFANNETEELMPLPISLAHKLSLRLTEVRKDQTLAYLRPDGKTQVTVEYDDQNKPVRIDTVVISTQHAPEVTLEQIQSDLKEHVISPVVPSELIDEQTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNIVAAGLADSCEVQLAYAIGVA... | Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | A8FGH7 |
Q6G8M7 | ACCA_STAAS | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Staphylococcus | MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Q6G8M7 |
B7J4C9 | SYS_ACIF2 | Seryl-tRNA(Ser/Sec) synthetase | Acidithiobacillus | MLDPSLLRSSPETVAAGLARRHFTLDVAALNALDQQRKALQIQLEQLRNARNEASRQIGQARRQGLDTGAMQAAAASNGEEIKTLEQSLERTLAEWDTLTIGLPNIPQDSVPDGRDEADNVVLRHWGSPSTFAFPPRDHVELGEALGIIDFAAGARLAGTRFVVLRGAGARLERALTQFMLDLHTTEHGYTEIAPPFLANADSLYGTGQLPKFEEDLFALRDDPYYLIPTAEVPLTNLLRGEIVASLPQRFCAYTPCFRREAGAYGRDTRGMIRQHQFDKVELVQIVRPEDSAQAHETLTAHAEKVLQLLELPYRVTALC... | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). | B7J4C9 |
B6JEU0 | RL16_AFIC5 | 50S ribosomal protein L16 | Afipia | MMQPKKTKFRKAHKGRIHGVASSGATLSFGQFGLKAMAPERITARQIEAARRALTRHMKRVGRVWIRVFPDVPVSKKPAEVRMGSGKGSPELWVVRVKPGRILFEIDGVNDQIAREALTLAAAKLPIKTRFVARIAE | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs. | B6JEU0 |
P0A7V0 | RS2_ECOLI | Small ribosomal subunit protein uS2 | Escherichia | MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE | Required for ribosomal protein S1 to bind to the 30S subunit. | P0A7V0 |
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