accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 16 2.75k | function stringlengths 6 5.51k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q2FTH1 | PDXT_METHJ | Pyridoxal 5'-phosphate synthase glutaminase subunit | Methanospirillum | MAGNAAVGVLALQGDVSEHISAFESAIQNLGLNIPVVPVRKAEQILDLMALAIPGGESTTIMRLIEKNGMRNIIQNFKGGIFATCAGMVVSARDLINETRFTPLDLLDITVNRNAFGRQRESFEADLQISGFDTPFHAIFIRAPVITRAGPDVTILAEIPQGIVAAKKGKKLILSFHPEISHDLRMHEYFLKDMLG | Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | Q2FTH1 |
A7I6C9 | FAEHP_METB6 | D-arabino-3-hexulose-6-phosphate formaldehyde lyase | Methanoregula | MYLVGEALIGEGAELAHIDLLLGSKEGPVGSAFANAVSQLSMGHTPLLAVVRPNLLTKPATVIIPKVTLKDMEQVNEMFGPVQAAVAKAIADSLEEGAFKDIDIEGIAIIASAFVHPEAKDYNRIYRYNYGATKLALHRALDKFPDEKTLVYEKDRAAHGIMGFKVQRLWDPPYLQVAMDLVDMGKVAQVLKEVPQNDHVIIEAGTPLIKKFGLNVIGEIRKLRPNAFIIADMKILDTGNLEARMAADATADAVVVSGLAPTSTIEKAISEARKVGIYSIIDMLNVQNPAKLIEKLKVKPDIVELHRAIDTEETAHAWGD... | Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate. | A7I6C9 |
B2SX42 | SYDND_PARPJ | Non-discriminating aspartyl-tRNA synthetase | Paraburkholderia | MSMRSQYCGLVTEELLGQSVSLCGWVSRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKAAEGVRNEFCLQIKGVVRGRPEGTTNAALKSGKIEVLCHELIVLNPSITPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDSLGFIDIETPMLTKSTPEGARDYLVPSRTNPGQFFALPQSPQLFKQLLMVANFDRYYQIVKCFRDEDLRADRQPEFTQIDCETSFLSEQEIRDLFEDMIRHVFKETIGVTLDEKFPVMLYSEAMRRFGSDKPDLRVKLEFTDLTDAVRDVDFKVFSTPANTKDG... | Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). | B2SX42 |
P38254 | TTL_YEAST | P-body-associated protein 1 | Saccharomyces | MRVLITNDDGPLSDQFSPYIRPFIQHIKRNYPEWKITVCVPHVQKSWVGKAHLAGKNLTAQFIYSKVDAEDNTFWGPFIQPQIRSENSKLPYVLNAEIPKDTIEWILIDGTPASCANIGLHLLSNEPFDLVLSGPNVGRNTSAAYITSSGTVGGAMESVITGNTKAIAISWAYFNGLKNVSPLLMEKASKRSLDVIKHLVKNWDPKTDLYSINIPLVESLSDDTKVYYAPIWENRWIPIFNGPHINLENSFAEIEDGNESSSISFNWAPKFGAHKDSIHYMDEYKDRTVLTDAEVIESEMISVTPMKATFKGVNHLLGEL... | Probable P-body-associated tubulin--tyrosine ligase. | P38254 |
B0SFU6 | MTND_LEPBA | Acireductone dioxygenase (Ni(2+)-requiring) | Leptospira | MATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGLEYRFDQLKKQHGYKANDLVVLHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFIIDGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFKDNSGWTPVYVDESKVLINA | Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine... | B0SFU6 |
P41086 | DHSD_RICPR | Succinate dehydrogenase hydrophobic membrane anchor subunit | typhus group | MIYDFKAEIIKAKNSSFSKSGSHHWLLQRVTGVILALCSFWLIYFMFTNKNNDINIIMWEFKKPFNIVILLITVTISLYHSVLGMRVVIEDYINCHKLRNTLIIIVKLFCILTIVSFVVAIFYSG | Membrane-anchoring subunit of succinate dehydrogenase (SDH). | P41086 |
F1N5S9 | FUND1_BOVIN | FUN14 domain-containing protein 1 | Bos | MATRNPPPQEYESDDDSYEVLDLTEYARRHHWWNRVFGHSSGPMVEKYSVATQIVMGGVSGWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEINNIIEEATEFVKQNIVISSGFVGGFLLGLAS | Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control. | F1N5S9 |
Q12QW7 | AMPA_SHEDO | Leucyl aminopeptidase | Shewanella | MEFSVKSGSPEKQRSACIVVGVYEPRRLSGIAEQLDKISEGYISNLLRRGDLEGKPGQMLLLHHVPNVLSERVLLVGCGKERELDERQYKQIITKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVETTQASLYSFDALKTRKGETRRPLRKMVFNVPTRKELTIGERAVEHGMAVSAGMHLCRDVANMPPNICNPAYLASQARQMAETHDKLKVTTIGEEQMAKLGMNSYLAVGRGSSNESIMTVMEYKGAVDSADKPIVLVGKGLTFDSGGISLKPGEAMDEMKYDMGGAAGVIGAMKALCEMNLPINVIGILA... | Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. | Q12QW7 |
P19447 | ERCC3_HUMAN | Xeroderma pigmentosum group B-complementing protein | Homo | MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPSAAGKQVDESGTKVDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ... | ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by ope... | P19447 |
Q31YE2 | ACCD_SHIBS | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | Shigella | MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTARNRLHSLLDEGSLVEMGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPLGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPEAPREGVVVPPVPDQEPEA | Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | Q31YE2 |
P34727 | ARF_AJECA | ADP-ribosylation factor | Histoplasma | MGMAFSKLFDRIWGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRVVEAREELQRMLNEDELRDALLLVFANKQDLPNAMSPAEITQQLGLQSLTRRAWYIQSTCATTGDGLYEGLEWLANALKKAGHE | GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. | P34727 |
Q6MG97 | BTNL2_RAT | Butyrophilin-like protein 2 | Rattus | MVDFPGYSLSGVAASFLFVLLTMKHPDDFRVVGPALPILANVGEDALLTCRLLPKRTTARMEVRWYRSDPDTPVMLYRDGAEVPGLAMEGYRGRVEWMEDSTEEGSVALKIRQVQPGDDGQYWCRIQEGDYWREASVLLQVAALGSSPNIHVEGPGEEGVQLVCTSRGWFPEPEVYWEGIRGEKLMSLSENHVYGEDGLFSVEDTLVVRNDSVETISCFIYNRGLREPQEATIALPEKLQTELASSRVIGPSQAIPVRVGETIELTCQLSPQTDAQSLEVRWLRARYYPVVHVYTNGAHEAGEQMAEYRGRTSLVTDAIH... | Negative regulator of T-cell proliferation. | Q6MG97 |
O60443 | GSDME_HUMAN | Gasdermin-E, C-terminal | Homo | MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFD... | Pore-forming protein produced by cleavage by CASP3 or granzyme B (GZMB), which converts non-inflammatory apoptosis to pyroptosis or promotes granzyme-mediated pyroptosis, respectively . After cleavage, moves to the plasma membrane, homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner d... | O60443 |
A1RHD6 | NUSB_SHESW | Antitermination factor NusB | Shewanella | MKPSERRKARRLAVQAIYSWQLSGNNIADVEHEFLTEQSLDGVDVAYFRELFSGVATKKPQLDELIIPHLERPIDEVSPVEKAIVRLATYELTFRKDVPYKVAINEAIELAKAFGADESHKFVNGLLDKLVARK | Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | A1RHD6 |
Q9R0D8 | WDR54_MOUSE | WD repeat-containing protein 54 | Mus | MFRRERSIPLRSSAAALSNNLSVLQLPARDLTHFGVVHGPSAQLLSAAPEGVPLAQRQLHVKEGAGVSPPLITQVHWCVLPFRVLLVLTSHRGIQMYESDGSVMVYWHALDSGDASSVQAMFARGIAASVHFICVGTCSGRVLVFDIPAKGPNIVLSEELAGHQTPITDIATERAQGQDGVADMVTADDSGVLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQGIVAAGYGNGQVRLYDASTGALHVQISAHARTISALDLAPEVGKLLSAAEDTFVHIWKLNRNPESGSIEVEHCHGECISDTQVCGARFCDPLGSSFAV... | When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation. | Q9R0D8 |
A3QGU9 | TPIS_SHELP | Triose-phosphate isomerase | Shewanella | MALRRPMVAGNWKMNGTAQLAQELFTKFATKLQNDSAEVVLCPPSIFLESVRQQLDANKEALNGCLVRMGAQNLSQHDFGAYTGEVSGQMLKDSGCRYVIIGHSERRRMYGETSDIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIEKNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPYIGENIRILYGGSVTPSNAADLFAQPDVDGGLIGGASLNSTEFLSLCSIAMSA | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). | A3QGU9 |
Q5ZRF3 | PAND_LEGPH | Aspartate 1-decarboxylase alpha chain | Legionella | MAYRKMLKSKIHRACVTQADLDYEGSITISPELLKVANILPYEAVNVWNITAGTRFETYAITGEKGSTDICVNGAAAHLVTPGDLVIIASFTQILEEDCAAHEPTVVFVDQFNRLKEIRPERIGVKSRIPNPA | Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | Q5ZRF3 |
Q12GW9 | RL23_POLSJ | 50S ribosomal protein L23 | unclassified Polaromonas | MSAVNSKTKFDEGRLMQVLVAPIVSEKATMIADKTNAVTFKVLQDATKFEIKAAVQLMFKVDVQSVAVLNIKGKTKRFGKSVGRRDNIRKAYVTLKPGQELNLGGESA | One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome. | Q12GW9 |
Q9PDM9 | RPOD_XYLFA | Sigma-70 | Xylella | MSNERTAQQSDIKQLISKGLEQGYLTYAEVNDHLPEDLVDPDQIEDIIGMINGMGIEVHEVAPDAETLLLNEGNTGNREVDDTAAEEAAAALSALDTEAGRTTDPVRMYMREMGTVELLTREGEIAIAKRIEEGLSEVQAALGVFPLSTELLLSEYELHKEGKRRLTEVVVGFNDLIEEDNSVTSSVDVTDESIVEVDEEDDDSVGNDEDAPTIGPDPAEVASRIESLSTEYAKFKKLYAKHGPEHKAVIKVREDVAAIFVTFKLSLPLTDLLVQQLQNMVNSVKDHERKVLHLATNVAKMPRKDFIRSWENNQTNLEWV... | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | Q9PDM9 |
Q9WTN6 | S22AL_MOUSE | Solute carrier family 22 member 9 | Mus | MLDYDEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTVNLSSAWRNHSIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNK... | Sodium-ion independent, medium affinity carnitine transporter. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 746. | Q9WTN6 |
P41324 | IL8_CANLF | Chemokine (C-X-C motif) ligand 8 | Canis | MTSKLAVALLAAFVLSAALCEAAVLSRVSSELRCQCIKTHSTPFHPKYIKELRVIDSGPHCENSEIIVKLFNGNEVCLDPKEKWVQKVVQIFLKKAEKQDP | Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection. Also plays an important role in neutrophil activation. Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled ... | P41324 |
A6WZD8 | APT_BRUA4 | Adenine phosphoribosyltransferase | Brucella | MESGFKASLKDAIRTIPDYPKPGVQFRDVTTLMGDAQAFRRSVDELVYPYAGNKVDKVAGIEARGFILGGAIAHQLSAGFVPIRKKGKLPRDTVRIAYSLEYGIDEMEMHRDAIEKGERIILVDDLIATGGTAEAAAKLLLQMGAEIVAACFIIDLPDLGGRKKLEALGVPVRTLVAFEGD | Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | A6WZD8 |
Q5XDT7 | NADD_STRP6 | Nicotinate mononucleotide adenylyltransferase | Streptococcus | MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLCMLELAIEDVEGLAIETCELERQGISYTYDTMLYLTEQHPDVDYYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKAGTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Q5XDT7 |
Q721N0 | TRML_LISMF | tRNA (cytidine/uridine-2'-O-)-methyltransferase | Listeria | MPNHIVLYQPEIPANTGNISRTCAGTDTYLHLIRPLGFSTDDKMLKRAGLDYWDNVKLSYYDSLDEFFEKNEGGEFYYITKFGRHVYSDIDYSDPNKDYFFVFGKETTGLPDALLQKNEENCLRIPMTDHIRSLNLSNTAAILAYEALRQQNFGALLQEPNYDRKIFQD | Could methylate the ribose at the nucleotide 34 wobble position in tRNA. | Q721N0 |
Q30RQ3 | SUCC_SULDN | Succinyl-CoA synthetase subunit beta | Sulfurimonas | MNIHEYQAKQIFAKYGVPTPKGLMAESVKQAVANAETLGGSIWVVKAQIHAGGRGLGGGVKLARSLEEVEQLSKEILGMTLVTHQTGPEGKLVQKLYIEEGADIKEELYLGVVLDRAREMPVIMASTEGGMAIEDVAHNTPEKIIKIAVDPAIGFQGFHGRELVFGLGITDPNEQKKLISFASKLYKLYMENDAEMIEINPLVKTGSGEFLALDGKMGFDDSALGRHPDIEDMRDISEEDADEREAGKYGLSYVSLDGEIGCMVNGAGLAMGTMDTINYMGGTPANFLDVGGKANAETVAKGFEIILKNPKVKAIFVNIF... | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat... | Q30RQ3 |
A4IZY4 | HEM3_FRATW | Pre-uroporphyrinogen synthase | Francisella | MKQITIASRESKLALWQTNFIKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFMKELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGAVVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERITQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCHVAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES | Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | A4IZY4 |
Q6IYG6 | CYB_MACMU | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Macaca | MTPMRKSNPILKMINRSFIDLPAPPNLSMWWNFGSLLAACLILQIITGLLLAMHYSPDTSSAFSSIAHITRDVKYGWITRYLHANGASMLFICLFLHIGRGLYYGSYLLLETWNIGIMLLLMTMTTAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVQWIWGGYAIDSPTLTRFFTLHFILPFIIIALTTVHLLFLHETGSNNPCGISSDSDKIAFHPYYTTKDILGLVLLLFILATLTLLSPNLLNDPDNYIPADPLNTPPHIKPEWYFLFAYTILRSIPNKLGGVLALFLSILILAAIPMLHKSKQQSMMFRPL... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q6IYG6 |
Q2W4D7 | LPXB_MAGSA | Lipid-A-disaccharide synthase | Magnetospirillum | MLIYLIAGEPSGDLLGGRLMAALKERLGEGVSFAGIGGESMRAEGLTSLFPMTELSVMGLVEVLPRIPKILRRVKQTISDIETKRPDALVTIDSWGFNGRIQAGLKARGVPVPRIHYVAPMVWAWKSGRTKTLARVLDLLLTLLPNEPEWFEKEGLKTLHVGHPVIEGAASRGDGAAFRVRHGFAPDRKLLCVLPGSRHSETAKLLAPFGETIALLARRFPDLAVVVPTVETVADEVSQAVKSWALPSMVVRGPEKYDAFAACDAALAASGTVALELAMARLPAVITYKVSPVSAFIATRFLGLSLKFVTLVNILVDEAV... | Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Q2W4D7 |
C1A6S0 | RL6_GEMAT | 50S ribosomal protein L6 | Gemmatimonas | MSRIGKRPIPVPAGVTVAIDGSAVTVKGPKGELSRVLPADIVVSQEGAELLVKRPSDEERHKALHGLTRTLVANMVEGVTTGFKRVLEITGVGYKAEIKPYGALLSLGFSHQIEYKAPQGVQITAPNPTTVVIEGASKEHVGQVAAEIRSLRKPEPYKGKGVKYQGEVVRRKAGKAGGK | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | C1A6S0 |
P31384 | CCR4_YEAST | Glucose-repressible alcohol dehydrogenase transcriptional effector | Saccharomyces | MNDPSLLGYPNVGPQQQQQQQQQQHAGLLGKGTPNALQQQLHMNQLTGIPPPGLMNNSDVHTSSNNNSRQLLDQLANGNANMLNMNMDNNNNNNNNNNNNNNNGGGSGVMMNASTAAVNSIGMVPTVGTPVNINVNASNPLLHPHLDDPSLLNNPIWKLQLHLAAVSAQSLGQPNIYARQNAMKKYLATQQAQQAQQQAQQQAQQQVPGPFGPGPQAAPPALQPTDFQQSHIAEASKSLVDCTKQALMEMADTLTDSKTAKKQQPTGDSTPSGTATNSAVSTPLTPKIELFANGKDEANQALLQHKKLSQYSIDEDDDIE... | Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. CCR4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity tow... | P31384 |
A4IQS1 | NUSB_GEOTN | Antitermination factor NusB | Geobacillus | MKRHEAREKALQALFQIDVGHIPPDEAIGNVTGSGEVDPFLRQLVFDVIEHRAEIDELLRSNLEKWKLERVANVDRVILRMATYEMKYVDDVPVSVSLDEAVELAKKFGDWKSGSFVNGVLSKVKAALQK | Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | A4IQS1 |
B1GZ77 | RS12_ENDTX | 30S ribosomal protein S12 | Endomicrobium | MPTINQLITNGRKGIIKKTKSPALKNCPQRRGVCTRVYTVTPRKPNSALRKVARVRLTSGYEISSYIPGEGHNLQEHSLVLIRGGRIRDLPGVRYHIIRGTLDTAGVDGRKQGRSKYGAKKAKVAKTASAK | Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com... | B1GZ77 |
Q04PV7 | RL15_LEPBJ | 50S ribosomal protein L15 | Leptospira | MKKERLEQAAAFGKERAKKKKNTDTTSNLVPVPKGAKKEKKRVGRGPGSKVGKTAGRGSKGQYARNTVRRGFEGGQMPIHRRLPKRGFTAKFHKEFYPVNLRDIEKSGLTGNIDAKIMVQSKILDKETTLFKILGTGEIKKAIHVIADGFSQSAKEKIEKAGGSIKLRAEIELAASETKK | Binds to the 23S rRNA. | Q04PV7 |
Q9DCU9 | HOGA1_MOUSE | Probable 2-keto-4-hydroxyglutarate aldolase | Mus | MLGPQIWASMRQGLSRGLSRNVKGKKVDIAGIYPPVTTPFTATAEVDYGKLEENLNRLATFPFRGFVVQGSTGEFPFLTSLERLEVVSRVRQAIPKDKFLIAGSGCESTQATVEMTVSMAQVGADVAMVVTPCYYRGRMSSAALIHHYTKVADVSPIPVVLYSVPANTGLELPVDAVVTLSQHPNIIGLKDSGGDVTRIGLIVHKTSKQDFQVLAGSAGFLLASYAVGAVGGICGLANVLGAQVCQLERLCLTGQWEAAQELQHRLIEPNTAVTRRFGIPGLKKTMDWFGYYGGPCRAPLQELSPTEEEALRLDFSNNGW... | Catalyzes the final step in the metabolic pathway of hydroxyproline. | Q9DCU9 |
Q4UZX0 | NPD_XANC8 | Regulatory protein SIR2 homolog | Xanthomonas | MTVAITQTGPALQEFVERHQRLFVLSGAGCSTDSGIPDYRDLQGGWKRPQPVTFQAFMGELSTRQRYWARSLVGWPRFGLARPNATHHALAALEARGQLELLLTQNVDRLHQAAGSQAVIDLHGRLDVVRCMGCEQRMPRTEFQLLLERDNPGWADLEAAQAPDGDADLDNVAFDNFVVPACPACGGVLKPDVVFFGENVPRERVERAFAHLQAADAVLVVGSSLMVYSGFRFVQAAARAGLPIAALNFGRTRADDLLSLKVEQSCAQALAFLQQPPDPLHTATARYHSARSA | NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | Q4UZX0 |
P02263 | H2A4_CHICK | Histone H2A-IV | Gallus | MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTDSHKAKAK | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | P02263 |
B7GGT8 | MDH_ANOFW | Malate dehydrogenase | Anoxybacillus | MGMKRKKISIIGAGFTGATTAFILAQKELGDIVLVDIPQLENPTKGKALDMLESSPVLGFDANIIGTSDYADTADSDVVVITAGIARKPGMSRDDLVTTNQGIMKAVTKEVVKYSPNCFIIVLTNPVDAMTYTVFKESGFPKNRVIGQSGVLDTARFRTFVAQELNLSVKDITGFVLGGHGDDMVPLVRYSYAGGIPLETLIPKERLDAIVERTRKGGGEIVNLLGNGSAYYAPAASLAEMVEAIVKDQRRVLPAIAYLEGEYGYEGIYLGVPTILGGNGIEKVIELELTEEEKAALAKSVESVKNVMKVLQ | Catalyzes the reversible oxidation of malate to oxaloacetate. | B7GGT8 |
B1YTB0 | PROA_BURA4 | Glutamyl-gamma-semialdehyde dehydrogenase | Burkholderia cepacia complex | MDIDQYMTDLGRRARHASRAMARASTAAKNAALDAVARAIERDAQALKDANARDVARAREKGLDAAFIDRLTLSDNALKTMVEGLRQVASLADPIGEIGNLKYRPSGIRVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALESNAALAKLIGEGLEAAGLPQDAVQVVATADRAAVGKLITMTDYVDVIVPRGGKSLIERLINEARVPMIKHLDGICHVYVDDRADLAKALTVCDNAKTHRYGTCNTMETLLVASGIAATLLPPLGKLYRDKQVELRVDAAARAVLAEAGVGPLVDATDEDWHTEYL... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. | B1YTB0 |
Q5K2N9 | K1C18_PROAT | Keratin-18 | Protopterus | MYSAVSSRSTVVSSRPLSSSRSLVVSSSYPKMSTASTTYSGVASSGSRISSTRYSTIGSALGGAGGFGTRSSLTLSGNAVISNEKETMQDLNDRLSNYLETVRRLENANQQLEIQIREAMEKRGPSVRDYSNYEKIIKELRDQIYDTTVDNARLVLAIDNARLAADDFRVKWEAELAIRQSVDSDINGLRKVIDDTNLGRLQLESEIEVLKEELVFIKKNHEDEVIALRNQVNSCGVQVDLDAPKGTDLAEIMATLRAEYEAMINKNKDDAEHWYQSKVETFQVETVQNTEALQTAKTELSDLRRRIQSLEIELESNRSM... | When phosphorylated, plays a role in filament reorganization. | Q5K2N9 |
Q9I816 | OR19A_DROME | Odorant receptor 19a | Sophophora | MDISKVDSTRALVNHWRIFRIMGIHPPGKRTFWGRHYTAYSMVWNVTFHICIWVSFSVNLLQSNSLETFCESLCVTMPHTLYMLKLINVRRMRGQMISSHWLLRLLDKRLGCDDERQIIMAGIERAEFIFRTIFRGLACTVVLGIIYISASSEPTLMYPTWIPWNWRDSTSAYLATAMLHTTALMANATLVLNLSSYPGTYLILVSVHTKALALRVSKLGYGAPLPAVRMQAILVGYIHDHQIILRLFKSLERSLSMTCFLQFFSTACAQCTICYFLLFGNVGIMRFMNMLFLLVILTTETLLLCYTAELPCKEGESLLT... | Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged o... | Q9I816 |
P02959 | SASA_PRIMG | Small, acid-soluble spore protein A | Priestia | MANTNKLVAPGSAAAIDQMKYEIASEFGVNLGPEATARANGSVGGEITKRLVQMAEQQLGGK | SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. | P02959 |
Q6KZV3 | EF1B_PICTO | aEF-1beta | Picrophilus | MGDVLVVFRVLPEDVDNDLSRLESKIREKLNGVCKINDIKTEEIGFGLKALNVQAIMPDEEGMADRVESILAGIEGVSQVDTKDISLI | Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | Q6KZV3 |
P11519 | FLMC1_ECOLI | F-plasmid maintenance protein C | Escherichia | MLRQHQDSLLLRFAQGEEGHETTTQLSCLVCVDRVSHTVDIHLSDTKIAVRDSLQRRIQGGGGFHGLRIR | Component of a type I toxin-antitoxin (TA) system (Probable). Either this protein or sequences upstream of it are required for translation of downstream flmA; this could be translationally coupled to flmA . | P11519 |
P9WEY7 | TPS1_PHYPO | Terpene cyclase TPS1 | Physarum | MNHPLRIHEIRLPWKHTPMNPHYAFVREQIVALLNELGLCEEEKEKDRRDGVITMGAYIYPDAGPNELLFGTLFVLWLFFFDDIFDESKFLKGESSQAAERTLQMFRTRQPPVNATTGLSMGIVQLEKLLLRIFKMAKDLAHGPYVISRFMETCEFYITEGAIPMDKFRFRKELPKLDEYLAVRTIDGAGEACIVCSEIVAHLALPEHIINEPRIKRMREITGQQIVYSNDIYSYHREKIHNNSVNALNIRCLTKSFNDALTDQINQVNEWVLEFEALKNSLYESTLWENNLDVYITGMENTMMGCKIWSESCTRYDLNA... | Terpene synthase that catalyzes the cyclization of farnesyl diphosphate (FPP) into a mixture of sesquiterpenes with gamma-muurolene as the most abundant compound and (-)-beta-caryophyllene, alpha-muurolene, and 4 unidentified sesquiterpenes as minor compoundss . TPS1 shows also monoterpene synthase activity and can als... | P9WEY7 |
A0A0H3G0N3 | ASCHD_ZYMMA | ASCH domain-containing ribonuclease | Zymomonas | MTDIPDRKEAVISLWPEFAKAIVSGKKTVEFRRRIPLPALSARIWIYATRPVKSVIGFAYLEAIVQGDVNTLWSRYGREAFLSEQQYRDYFEGTEKATAFLLRDHQPIRPINLDQLKEIRANFQPPQSLTWLRKEETQKLVSLTSQVE | Shows sequence-specific endoribonuclease activity towards single-stranded RNA (ssRNA), with a preference for the bond between pyrimidine and adenine nucleotides. May also have 5'-exonuclease activity. | A0A0H3G0N3 |
O94716 | NKP1_SCHPO | Sim4-mal2-associated protein 4 | Schizosaccharomyces | MDIYEHKKSFMERQIRLLNRPMRPPKDWKLPLKSGQLSESVVETVFQRLQLRIQKHAKLNYSHQATQHVAAQIRKLYEQNSAIEDITFLNPLFYGEIDLSNLDSVKSLPHPWPFQKESRPVEKDEEQEKFNRLTGELLGLLTTLSELEQERSELEQIEKMLEPFEDGPSSIHTNMWKKNPELISTLNSTNTMVAKINSLLRGVSFPSLNNDNQEASLEDEIRSQLFEKTISDD | Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), whi... | O94716 |
A1TJ05 | EFTU_ACIAC | Elongation factor Tu | Acidovorax | MAKGKFERTKPHVNVGTIGHVDHGKTTLTAAIATVLSAKFGGEAKKYDEIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLDKYDFPGDDTPIVRGSAKLALEGDKGPLGEQAIDKLAEALDTYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRVERGIIKVGEEIEIVGIRDTQKTTCTGVEMFRKLLDQGQAGDNVGLLLRGTKREDVERGQVLCKPGSIKPHTHFTAEVYVLSKDEGG... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. | A1TJ05 |
Q863F8 | COX8B_EULFU | Cytochrome c oxidase subunit 8H | Eulemur | MPRLPPALRLLQPPLRCWVVPKLHVSAKPARTPTSPAEQAVGLSMMFLSFLVPAGWVLSHLESYKKSSTA | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | Q863F8 |
Q96MM7 | H6ST2_HUMAN | Heparan-sulfate 6-O-sulfotransferase 2 | Homo | MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRNFHY... | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. | Q96MM7 |
P81705 | IBB_ERYVA | Bowman-Birk type proteinase inhibitor | Erythrina | TSACCDKCFCTKSNPPICQCRDVGETCHSACKFCICALSYPAQCHCLDQNTFCYDKCDSDS | Strong inhibitor of trypsin with a 1:1 stoichiometry. Weaker inhibitor of chymotrypsin. | P81705 |
Q6AL57 | GREA_DESPS | Transcript cleavage factor GreA | Desulfotalea | MIDRIPMSVRGNKKLKEELLRLTRVERLDVVKAIEVAREHGDLKENAEYHAAKERQGMIEARIMDLKDKLGRAEVIDCLQVSCKRVVFGTVVVLLDLDTDEEVTYQLLGPEESEVKAGSISVLSPIGRSMLSKEEGDEVVTKTPGGTREFEVVEIKTGDFA | Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor... | Q6AL57 |
P20821 | GCSH_BOVIN | Lipoic acid-containing protein | Bos | MALRAVRSVRAAVGGLRAISAPSAPCLPRPWGLRAGAVRELRTGPALLSVRKFTEKHEWVTTENGVGTVGISNFAQEALGDVVYCSLPEVGTKLNKQEEFGALESVKAASELYSPLSGEVTEINKALAENPGLVNKSCYEDGWLIKMTFSNPSELDELMSEEAYEKYIKSIEE | The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). | P20821 |
A6QNP9 | CCD69_BOVIN | Coiled-coil domain-containing protein 69 | Bos | MGCGHSRLSCCKPPKKRRQRPDQPPKPEPQELGPLNGDTATTDHVCASEEAEQHQKAITRILQQHEEDKKKWAQQVEKERELELGEKLNEQRKVLEGEHVEALRVLQASYEQDKEALTHSFQEAKAALQETIDRLTAQIEAFQAKMKRAEESILSRDYKKHIQEHGSLSQFWEQELESLHFVIEMKNERIHELDKRLILMETVKEKNLLLEEKITTLQQENEDLHARGRNQMVVSRQLSEDLLLAREALEKESQSRRQLQQEKEELLYRVLGADAAPAFPLASVTPTEVSFLAT | May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone. | A6QNP9 |
B2Y1W1 | ATPF_WELMI | ATPase subunit I | Welwitschia | MKEVINSLNYLSNWPSAGSFEFNTNILETNIINISVVLGVLVYFGKGVLSNLLDNRKSKILNTIQNSEELCKGATDQLEKARARLWEVEKRVDEIRVNGYLQIEQEKENLIKAASANLKQLEDSKNETIFFEQQKVIDQVRQQISYQALQKALAIMNNCLNTDLHLRMIDYNIGRLRAKKPN | Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). | B2Y1W1 |
Q6D299 | THIM_PECAS | 4-methyl-5-beta-hydroxyethylthiazole kinase | Pectobacterium | MNTQPADFSAAQAATSLTQFRSAAPLVHCLTNDVVQSFTANVLLALNASPAMVVDPEEAAQFSAVADALLINVGTLERTRAEAMRAAVNSAHQAGTPWVLDPVAVGGLTFRTEFCRELLTWKPAAIRGNASEIMALAGLAAQGRGVDSADDSLAALPAARELARQVGTIVVVTGAVDYVTDGERDIAVTGGDSMMTRVVGTGCALSAVVAGFCSLEGDRLSHVTAACYVMALAGQQATSVSQGTGSFIPHFLDRLYTLRAEDLA | Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). | Q6D299 |
A3CQM4 | RS12_STRSV | 30S ribosomal protein S12 | Streptococcus | MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIVRGALDTAGVTDRKQGRSKYGTKKPKA | Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com... | A3CQM4 |
Q6IE81 | JADE1_HUMAN | PHD finger protein 17 | Homo | MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE... | Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity . Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation . May also promote a... | Q6IE81 |
Q12EL8 | MRAY_POLSJ | UDP-MurNAc-pentapeptide phosphotransferase | unclassified Polaromonas | MLLSLAQWLQSISPEFGSFRVFQYLTFRAVMAALTALLIGLLAGPFVIRRLISLKIGQPIREYAMQTHLSKSGTPTMGGVLILMSIGISTLLWFDLSNRFVWIVLLVTLGFGAIGWADDWRKVVLKDPEGMRSREKYLWQSLIGLVAALYLVFSISESSNLRVLELFFSWVQSGFDVDLPPKAGLLVPFVKEISYPLGVFGFVILTYLVIVGSSNAVNLTDGLDGLAIMPVVMVGSALGVFAYVTGSAVYSKYLFFPHIPGSGELLIFCSAMAGAGLAFLWFNTHPAQVFMGDVGALALGAALGTIAVIVRQEIVLAIMG... | Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I... | Q12EL8 |
A5VZ54 | MURA_PSEP1 | UDP-N-acetylglucosamine enolpyruvyl transferase | Pseudomonas | MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIA... | Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. | A5VZ54 |
E2QSX5 | IFT43_CANLF | Intraflagellar transport protein 43 homolog | Canis | MEDLLDLGGERRRGSTTSGPRMGRRAQQESAQVENHLSGKNSSILTGEVAPPPKPPRRQGGWADDSMKTSKSGRRASEEVEEGSHRLRQQSFGGSDDGGDIPVIPDLEDVQEEDFALQVAAPPSIQVNRVMTYRDLDNDLMKYAAFQTLDGEIDLKLLTKVLAPEHEVREDDVNWDWDRLYTEVSSELLSEWDLLQSEKEDPMGQPAHT | As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis. Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base. | E2QSX5 |
Q1LTX5 | KAD_BAUCH | Adenylate monophosphate kinase | Candidatus Baumannia | MRIILLGAPGSGKGTQAQFIMKKYGIPHISTGDMLRTTVNKESVLGKNIQAIIKLGNLVPDQLVIELVKERIIQYDCSKGFLLDGFPRTLTQAYAMEVAGINVDIVLILRIPDKIIINRIVGRMVHEPSGRIYHVTFNPPKQKGKDDITGENLIIRQDDKEDTVRHRLIGYHQQMIPIITYYNNANIRNIRCFTIDANCPISTLNEKIVRILG | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Q1LTX5 |
B9W923 | AIM21_CANDC | Altered inheritance of mitochondria protein 21 | Candida | MSDLEPSESLNHESDSHLEQLKPSTTPSIPARPQSRPQKQTTTTTTKVPTDQDSNDKTPLEKPQDELDQLAHEIEKVLTDPVIPPRPQHGSSAKPNETQTEHKEQDFGSAHPVIPSRPTNKKETIETEMVDQNNGLESKSDSTANKESLENQVPIDEDSTHVKPSIPNVPSRPQNRDLDSSEVDNTKASTTPSIPARPQRQTAPTQNEHKPQVSNTPVIPTRPQTKTEKLHLNEELDKLDGESSSKNQENKRHTDDNNTSKPIYEAESIVPPEEKEGETANKQALPTTSTDPPAEPTASTRGFRLPLHMQQSSGPISTST... | Involved in mitochondrial migration along actin filaments. | B9W923 |
H1ZZI0 | SCX11_TITOB | T NaTx14.9 | Tityus | MTRFVLFISCFFLIGMIVECKDGYLVGNDGCKYNCLTRPGHYCANECSRVKGKDGYCYAWMACYCYNMPNWVKTWSRATNKCGKRK | Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. | H1ZZI0 |
A4G074 | COFC_METM5 | 2-phospho-L-lactate guanylyltransferase | Methanococcus | MLAALIPVSPLSNVKSRLKEFLSSDERIELIKNILLDTYETVKECSDACYVVSKDEEILEFSKNLGIIPIREESNVKGLNEAINFSLKFIKEDSILITPADVPLLKEENLKTITSKSVENSIVICPSRGGGTNLLLLNPKDCMKTQFEGFSFLKHIEEAEKNDLKVIKCHSFYTSIDVNTVEDLGEIYIHGTDTKTYQYLKHLGVEVLPKHSSAGRFNVIRK | Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. | A4G074 |
Q3APH9 | RS3_CHLCH | 30S ribosomal protein S3 | Chlorobium | MGQKVNPTGFRLGIIRDWTSRWYDDSPVISEKIKQDHIIRNYVLARLKKERAGIARINIERTTKHVKINIYAARPGAVVGRKGEEINNLSQELSRIIGKEVKIDVVEVIKPEIEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRAGAEGVRIRCAGRLGGAEIARAEQYKEGKIPLHTIRANVDYASVTAHTIAGTIGIKVWVYKGEVLVQRIDAIEEDEMKKMKDRRNDGGAKGRDSRDNRSKRRSRSKRS | Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation. | Q3APH9 |
Q0S2C5 | TRMD_RHOJR | tRNA [GM37] methyltransferase | Rhodococcus | MRLDVVTIFPEYLEPLRAALLGKAIDKGLISVEVHDLRDWTHDVHKAVDDSPYGGGPGMVMKPTVWGPALDDVLAAGDGDTDTLLVVPTPAGVPFTQATAERWAGEKRIVFACGRYEGIDQRVFDDAARRVRVEEVSIGDYVLIGGEAAVLVMTEAFVRLIPGVLGNQQSHQEDSFSDGLLEGPSYTRPATWRGLDVPPVLLSGDHAKVAAWRREQSLQRTAERRPDLLP | Specifically methylates guanosine-37 in various tRNAs. | Q0S2C5 |
O48726 | RPN13_ARATH | 26S proteasome non-ATPase regulatory subunit 13 | Arabidopsis | MSSSEAFPVMQEIMLEFRAGKMSLQGTRVVPDARKGLVRIARGDEGLIHFQWLDRNQNTVEDDQIVFPDEALFEKVNQSSDRVYILKFNSDDRKLFFWMQEPRAEGDAELCSSVNQYLNQPLEFPGEEGLAAAITEELEDMAEDNTSSRAGNLVVPNLSSEVSDVTSSSGPVKLADLQRILNNLSGGPVGIAGDQDEGLALGDILKPELIMPLLEALPVQERLSSHLPEGHSRAEDILELLQSPPFRQQVDAFTYVLRTGQIDLTQFGIDPSKYKFTVDSFLEALEDSVSTQSRDAMDES | Functions as a proteasomal ubiquitin receptor. Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-63'-linked ubiquitin chains. | O48726 |
A6MML6 | ACCD_DIOEL | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic | Dioscorea | MEKWWWFNSILSNERLEHRYGLSKSMDSVNGIEYTKDPILNDTEKNILGWSDSSNYSFSTVDYLFEIRNIWSLISDDTFLVRDSNGDSYSVYFDIENQIFEIDNNSSFLGELESFFSSYLNRGSKNKYYHYMYDTQFSWNNHITNCIDSYLRFEIGISITSYISGDIVNYSDGYIYSFICTESVSSNESGSSSIRTSSNGSDFNMRENSNDSDINKKYRHLWVQCENCYGLNYKKFFRSKMNICEQCGYHLKMSSSDRIEVSIDPDTWDPMDEDMVSIDPIEFHSEEEPYRDRIDSYQRKTGLTEAIQTGIGQLNGIPIA... | Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | A6MML6 |
Q97BG1 | COBS_THEVO | Cobalamin-5'-phosphate synthase | Thermoplasma | MMISGLRSSFSFFTLVPSRQKDIGNPITFLPLVVTVGALIGDSILYITWQFSHLIASFLSISSIIIYNGLNHFDATADLGDALMVRDKSRIPEVIKDHHVGAGGIFAVIFVYGIAVLSLARSTLYIGLVGILIGQVVSGSSMMISLIGSQPFVPGLADYFISLFRKHSVGYTIEFLAIPIIVSFIFSPLYVVIVALNLLIVQLTKTMISRRFGGINGDVIGFLGEFSRSLFIFMLIIIAHYNVASTYDIFSKMLSSFTS | Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate. | Q97BG1 |
A0RAX6 | ADDB_BACAH | ATP-dependent helicase/nuclease AddB | Bacillus cereus group | MSLRFVIGRAGSGKSTLCLHEVQEELKQRPRGETILYLVPEQMTFQTQQALIGSEDVRGSIRAQVFSFSRLAWKVLQEVGGASRLHIDEAGVHMLLRKIVESRKDGLSVFQKAAEQNGFFEHLGSMIAEFKRYNVTPSNVYEMWQQLDAHSSSAEQKLLANKVYDLQLLYDDFERALIGKYLDSEDYLQLLVENLPQSEYVKGAEVYIDGFHSFSPQELEIVRQLMICGARVTITLTIDEKTLAQPVNELDLFYETTLTYEKIKQVAREEKIEIEKTIPLMEQPRFHSPALAHLEMHYEARPNEKFHGEASVTIHTAANL... | The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5... | A0RAX6 |
Q8MIK0 | ANDR_CROCR | Nuclear receptor subfamily 3 group C member 4 | Crocuta | MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEATSAAPPGARLQQQHQHQQQHQHETSPRRQQQQQPEDGSPQRPSRGPTSYLALDEEQQPSQHQSAKGHPESGCVPEPVAMSRTGKGLEQQQPAPPDEDDSAAPSTLSLLGPTFPGLSSCSTDLKDILSEAGTMQLLQRQRQRQQQRQQQQQQQQQQQQQQQQQQEVVSEGGSSGRAREAAGAPTSSKDSYLGGSSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGGPPPVCPCAPLTECKGSVLDDGPSKGTEETAEYSPFKT... | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the... | Q8MIK0 |
Q3MF82 | DEOC_TRIV2 | Phosphodeoxyriboaldolase | Trichormus | MAADYPNIDIAPFIDHALLTPTATPEQVDQWCEQADRYNFASVCLYPTYVKQAAEFLHGKKPKVCTVIGFPTGATTRSVKLYEALEAVENGATELDVVINLGCLKSGNTEAVHREIAEICEETGQVVKVILETNLLTDAEKKIAADIAMDAGATFLKTNTGWNGGATVADVRLLKEITRERVGIKASGGIRTLNQALDLILAGATRLGTSRGIDLIHQRDNPEKVE | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. | Q3MF82 |
B8DN92 | RS12_DESVM | 30S ribosomal protein S12 | Desulfovibrio | MPTINQLIRKERKAVLKRKKTPALQACPQRRGVCTRVYTTTPKKPNSALRKVARVRLTNGIEVTAYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIVRGTLDTAGVQDRRQGRSKYGAKRPK | Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com... | B8DN92 |
Q9D4W2 | MFI_MOUSE | Protein C11orf65 homolog | Mus | MSVKHIQDNSNQEIAARIIQRAWKTFLNVSVYQHFKSLIDLRRQGEPRQIVRYINPKEAQLLDAAAGVQVRFRLGGVRFPPEIYYKIFTHRHIEDLCANSPRDYTKLPARYTSHNKDDPPQVEDNSGWYRRVENNGWRPVSYRFWMPLESGVVDSTKESEFHFSKLKRKQDLEKKRKIKKIDWMRQMYYMGSLEAKATDNETLGLIHKATKGLIKSIEDGGVDSVMEWEVDEVLNWTNTLNFDEYIASWRETATSNSSANLKDVKLQRIQKSLQSNIYGDEAKQAEESLYDDSTYYENAYTKQFTRLTPDSMFGM | Acts as an inhibitor of mitochondrial fission. Interacts with MFF and prevents DNM1L recruitment to mitochondria, promoting a more fused mitochondrial network. | Q9D4W2 |
Q9W5E0 | SUV42_DROME | Suppressor of variegation 4-20 | Sophophora | MVVGSNHTRRGETGSRFTNSSSSSSTSGGPTASASSTTSVTSSLATNSTSTSTAAALLSSMSHKSHGPPPSAPPSAHHQTNQQHHQVAHSQPHATHYQQTNQHPSHHHQSHQSSNGSGGGSAGSGSGSGSVVSGLNGCNGSAVSRLSQSTGMSPRELSENDDLATSLILDPHLGFQTHKMNIRFRPLKVDTQQLKAIVDDFIHTQNYDIAIQRIYEGPWIPRHLKNKNKIATKRLHDHIVRYLRVFDKDSGFAIEACYRYTLEEQRGAKISSTKRWSKNDKIECLVGCIAELTEAEEAALLHSGKNDFSVMYSCRKNCAQ... | Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin i... | Q9W5E0 |
B8F6E6 | ISPH_GLAP5 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | Glaesserella | MNIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVDGLKAKGAIFVEELDEVPDGAIVIFSAHGVSQAVRHEAKRRELKVFDATCPLVTKVHMQVARASKKGTKAILIGHEGHPEVVGTMGQYDNEKGGIFLVEDVEDIAKLGLKEDEDLTFMTQTTLSIDDTIDVIEALKQKYPAIQGPRKNDICYATTNRQQAVRELAKLAQLVLVVGSKNSSNSNRLAELASRMGTPSQLIDGPQDIDPNWLQGVTTIGITAGASAPEVLVQSVVEHLKTLGVTKVEELEGCEENTVFEVPRELRITEVN | Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | B8F6E6 |
C4K0F2 | TRUB_RICPU | tRNA-uridine isomerase | spotted fever group | MSNYWLNIYKPRGISSAQLVSIVKKILGRTKIGHAGTLDVEAEGILPFAVGEATKLIHLLIDARKTYIFTVKFGMQTNSGDCAGKVIATKYCVPSQEEAYAVCSKFIGNVTQIPPAFSALKVNGVRAYKLAREEKKVELKPRNTTIYDLKCLNFDEKNATATYYTECSKGTYIRTLAEDLALSLQSLGFVIELRRTQVGIFKEENAIRIKSPDEITKNALEEKSIKIEAILDDILVLDATDSQAQQIKYGQKCLFNYEKDFRHLAKFAYREEFKGNTERSTTAYTLVREDASTGLTYKLPLEVEFGKMSIDLVWVRYKGT... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. | C4K0F2 |
P0DKS1 | MSCS_WIGBR | Small-conductance mechanosensitive channel | Wigglesworthia | MNIYKEIDNASNWISDNHILFIKYISNIILSLIILIVGYSASKVTQKIIKNFMIKKNIDIIISEFFCSIIKYSILIFTIVTSLGCIGIQTTSIIAVIGAAGIAIGLALQGSLSNFAAGVLLVTLRYFRTGDYVNLCGVKGKIKTVQIFCTKIKTKDGKIIIIPNNKIISSNIINYSEELHRLMEVIISTEYTSDIKNVKEIIIDVLKKETRIVKEKKITVRLKNLGESSLDFLVRGWVYKKELKQTTSDILEKIKIELDKNKINIPYKQIDVNLKYSKEK | Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance w... | P0DKS1 |
Q72J39 | MIAB_THET2 | tRNA-i(6)A37 methylthiotransferase | Thermus | MPPCYPFLLSWEGWARDPPGRPGGAMRAHIITYGCQMNEYDSHLVASELVSLGWELVDSVEEADFVLVNTCAVRGKPVEKVRSLLGQLRKEKERRGLLIGMMGCLAQLDEGQQMAKKFGVDVLLGPGALTSLPEALKANERFFDLTFREDVLDYIPPPPKGALSAHVTIIRGCNHHCTYCIVPTTRGPEVSRHPDLILKEIELLKQAGVVEVTLLGQNVNSYGKDQPGFPSFAELLRMVGGMGIPRVRFLTSHPVNFTDDIIEAIAETPAICRYIHLPVQSGSDRVLRRMAREYRRAHYLERIRKIREALPDAVLSTDII... | Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Q72J39 |
Q82K41 | DXR_STRAW | 2-C-methyl-D-erythritol 4-phosphate synthase | Streptomyces | MILGSTGSIGTQAIDLVLRNPDRFRVTGLSAAGGRVGLLAEQAHRLRVSTVAVAREDVVPVLREALTAQYGPGEPLPEILAGADAATQLAASDCHTVLNGITGSIGLAPTLAALEAGRTLALANKESLIVGGPLVKALAKPGQIIPVDSEHAALFQALAAGTRADVRKLVVTASGGPFRGRTKAELANVSPEHALAHPTWAMGPVITINSATLVNKGLEVIEAHLLYDIPFERIEVVVHPQSYVHSMVEFTDGSTLAQATPPDMRGPIAIGLGWPERVPDAAPAFDWTKASSWEFFPLDNDAFPSVGLARHVGQLAGTAP... | Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | Q82K41 |
Q3A9T9 | IF1_CARHZ | Translation initiation factor IF-1 | Carboxydothermus | MSKDDVIEVEGTVVEPLPNAMFRVELDNGHKVLAHVSGKIRMNFIRILPGDRVTVELSPYDLTRGRIIYRHK | One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-... | Q3A9T9 |
Q2HDW0 | ERB1_CHAGB | Eukaryotic ribosome biogenesis protein 1 | Chaetomium | MGSKITDKKRKSRDSESESDDELANGLFDGILSQSEDEEDYLPSDDDDDVEDSENEGTGASEDDDDDDDDDDILSDDIPSDVDSEEAINRLVKQQEELEITEPGVDPKREEDDGADRNYRIEKDANGGERYVYDEIDPVYDSDDSDAKGPVNTIGDIPLSFYDSYPHIGYDINGKKIMRPATGDALQSLLDSIEVPKGWTGLTDVDTGNPLNLTQDELELVRRVQMGLLPTDLQDPYPDTVEYFTSIEEKMPLSSAPEPKRRFLPSKNEAKQIMKLVRAIREGRILPYKPPEEREREEEEQEEVHFDLWQNEEPQAPNPM... | Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Q2HDW0 |
A1KCI5 | ALR_AZOSB | Alanine racemase | Azoarcus | MRPATALIDLDALRHNYRLARSRHGGRALAVVKANAYGHGAVRCAQALAAEADGFAVAFLDEALELRAAGITQTIVLLEGVFDAAELEQVVAHGLWPVVHHAAQIEMIEQAALARPLDIWLKVNSGMNRAGFVGDAVGSAWQRLRASGKVGEITLMTHFARADEPQVIATAEQLADFDTATRGLPGPRSLANSAAVLGWPDAHADWARPGILLYGADPMPGEGNGLQPVMTLESGVIAVRDLAAGAPLGYGARYVAERPRRIGLVAMGYADGYPRSAPDGTPVVVDGQPSMLVGRVSMDMLTVDLTDLPQAGIGSRVELW... | Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. | A1KCI5 |
O60404 | O10H3_HUMAN | Olfactory receptor OR19-24 | Homo | MPGQNYRTISEFILSGFSAFPQQLLPVLFLLYLLMFLFTLLGNLLIMATVWIERRLHTPMYLFLCALSISEILFTVAITPRMLADLLFTHRSITFVACAIQMFFSFMFGFTHSFLLMVMGYDHYVTICHPLHYNMLMSPRGCAHLVAWTWAGGSVMGMMVTMMVFHLTFCGSNVIHHFLCHVLSLLKLACGSKTSSVIMGVMLVCVTALIGCLFLIILSFVFIVAAILRIPSAEGRHKTFSTCVSHLTVVVMHYSFASLIYLKPKGLHSMYSDALMATTYTVFTPFLSPIIFSLRNKELKNAINKNFCRRFCPLSS | Odorant receptor. | O60404 |
Q8K9S8 | RRF_BUCAP | Ribosome-releasing factor | Buchnera | MINDIYIKSNEKMKVCINNFQIQVNNVRTGRASPELLNSIYVEYFGSKVPLRQISNVVVENYHTLKINIFDDSSTSLIKKAILNSNLDLNPILYGKDIIVPIPGLTEERRTHLIKVIRNNAENARIYIRNIRRDANDKIKNYLKSKIISEDNEHAAQNKIQTMTDDYIKKIDKILSEKEKDLMKF | Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. | Q8K9S8 |
C1B4A1 | DCUP_RHOOB | Uroporphyrinogen decarboxylase | Rhodococcus | MSERATYAARRVLPDAPLLAAAEGRAPGRRPVWFMRQAGRSLPEYREIRSGIGMLESCFDPALVCEITMQPVRRHGVDAAILFSDIVVPLKAAGIDLDIVAGTGPVVANPVRSIADVAALPRLVPEEVGAVAQAVQLLTAELGSTPLIGFAGAPFTLASYLVEGGPSRNHERTKALMHSDPKTWHALLGTLADTTITFLQAQLRAGVDAIQLFDSWAGALSLAEYREFVLPHSERVFAEVESAKVPRIHFGVGTGELLGAMGEAGADVVGVDWRIPLDVAARRVGPGKALQGNLDPAVLFAGSAAVEKQVRRITAEADAA... | Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | C1B4A1 |
A7Z0N2 | RS12_BACVZ | 30S ribosomal protein S12 | Bacillus amyloliquefaciens group | MPTINQLIRKGRVSKVENSKSPALNKGYNSFKKEHTNVSSPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVENRAQGRSKYGTKRPKAK | Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com... | A7Z0N2 |
P01508 | CECB_HYACE | Immune protein P9 | Hyalophora | MNFSRIFFFVFALVLALSTVSAAPEPKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG | Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. | P01508 |
P18298 | METK2_RAT | Methionine adenosyltransferase II | Rattus | MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQINDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVIPIRVHTIVISVQHDEEVCLDEMRDALKEKLIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSY... | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. | P18298 |
B1YR34 | HISZ_BURA4 | ATP phosphoribosyltransferase regulatory subunit | Burkholderia cepacia complex | MSTWLLPENIADVLPSEARKIEELRRRLLDRFRSYGYEMVMPPLLEYLESLLTSGGADLRLRTFKLVDQLSGRTLGLRADITPQVARIDAHLLNRQGVTRLCYAGHVMHTRPRGLHATREQIQIGAEIYGHAGLEADLEIQQLMLDALHLAGLSRIRLDLCHAGVLAALLARDPQAAERGESLYDALSGKDVPLLNELTDDLGADTRAALCALPHLYGDASVLDEARARLPVLPEITRALDDLAQLAAQAKGVEVAIDLADLRGYAYHSGAMFTAYIDGVPNAIARGGRYDHVGQAYGRARPATGFSLDLRELARISPIE... | Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | B1YR34 |
O48965 | IDI2_CAMAC | Isopentenyl pyrophosphate isomerase II | Camptotheca | MSAASHIHSVACRLSSSFLASPKLKLHPRLSFFFHSSSFRNHIITRSVFCSSSHLSVRVSSYHSSVAAKATTSAMGDTATDAGMDAVQRRLMFEDECILVDENDHVVGHDTKYNCHLMEKIESDNLLHRAFSVFLFNSKYELLLQQRSATKVTFPLVWTNTCCSHPRYRESELVDENALGVRNAAQRKLLDELGIPAEDVPVDQFIPLGRMLYKAPSDGKWGEHELDYLLFIIRDVNVHPNPDEVADVKYVNQDQLKDLLRKVDAGEEGLKLSPWFRLVVENFLFKWWDHVEKGTLQDATDMKTIHKLT | Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | O48965 |
Q7ZSY6 | MT2_DANRE | Metallothionein-2 | Danio | MDPCECAKTGTCNCGATCKCTNCQCTTCKKSCCSCCPSGCSKCASGCVCKGNSCGSSCCQ | Metallothioneins have a high content of cysteine residues that bind various heavy metals. | Q7ZSY6 |
Q12175 | MSH5_YEAST | MutS protein homolog 5 | Saccharomyces | MSHEWLISASETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNREEDSSTIFSFDFDEEIVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSHDLIDDADMSSNDISLLLGLLIMEANPTVCLVPARLEDWIFDYIKTKCDEINCRLELQPIKRFKKWDLLQSLQLRGHDNQTILNDILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTASSNMVTGRLVQNAFEDVIHGIRYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMRNGFFSVFELFNQVSSDYARRILKSWLINPLTNKKRIETRYSIIRTLL... | Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis. | Q12175 |
P47496 | DNLJ_MYCGE | Polydeoxyribonucleotide synthase [NAD(+)] | Mycoplasma | MMDVKLKIQQLVNLIKNYDYHYYVLSEPLIDDFEYDMLYKSLQQLEKDHPDLIQIDSPTQRVGGEAVKGFKKLNHNSPMLSLENAFSTKEIANFIDNINFQTNSKNEFVVEPKIDGVSISLTYKNGVLVHALTRGDGSVGEDVLNNVKTIKSIPLTIPFTKTIEIRGEIFVDKKTFLAINNQLEKPFANARNLAAGTIRNLNSEITAQRKLRALFYYIPNGLEESITTQTMVLEQLKQWKFPVSDTIRVFQNKFQLINYLEAFDKKREQLTFNLDGLVIKLNSLLFYQQLGATSKSPRWAIAFKFSPKFVQTKLTAVLIT... | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | P47496 |
Q9PLM7 | PSD_CHLMU | Phosphatidylserine decarboxylase beta chain | Chlamydia | MESQEFLYVNRETGAVEKEPVCCSFAIKFFLETRLGRGVYSFLCKNSLFSRIVGRFQRLRMTRRFIRPFVEKYRICEDEALRPLCDFTSFNDFFIRKLKPEARPICGGSEICVTPADGAYLVFPSIKDVSLFSVKNQLFSLNSLLEDQQLASEYAEGSMAIARLAPFDYHRFHFPVEGIAGTPRLINGYLFSVHPLMLKRNLKVFAENKREITVIESKEFGKVVYIEIGALNVGSIHQTFAPGSYVGKGAEKGFFAFGGSTVVLLFEPQRIIFDADLVHHSAQGLETRCRMGQSLGKRFSS | Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | Q9PLM7 |
P30308 | MPI1A_XENLA | M-phase inducer phosphatase 1-A | Xenopus | MAESHIMSSEAPPKSNTGLNIRTNCRMILNLLREKDCSVTFSPEQPLTPVTDLAVGFSNLSTFSGETPKRCLDLSNLGDETAPLPTESPDRMSSGKLESPKTQFVQFDGLFTPDLAWKAKKCPKRNMNSVLPHLLCSTPSFKKASGGQRSLSNKENEGELFKNPNCKPVALLLPQEVVDSQLSPTPENKVDISLEEDCEMNILGSPISADPPCLDGAHDDIKMQNLDGFADFFSVDEEEMENPPGAVGNLSCSMAILLSGPLLNQDVEISNVNNISLNRSRLYRSPSMPEKLDRPMLKRPVRPLDSETPVRVKRRRSTSS... | This protein functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It may directly dephosphorylate p34(cdc2) and activate the p34(cdc2) kinase activity. | P30308 |
B2VHQ1 | TGT_ERWT9 | tRNA-guanine transglycosylase | Erwinia | MKFELDTTDGRARRGRLVFERGVVETPAFMPVGTYGTVKGMTPEEVQDTGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEKGVHFRNPINGDAIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAQRSRDRFDSLGNKNALFGIIQGSVYEDLRDVSVKGLVDIGFDGYAVGGLAVGEPKEDMHRILEHVCPQLPQDKPRYLMGVGKPQDLVEGVRRGVDMFDCVMPTRNARNGHLFVSDGVVKIRNAKYKDDISPLDAECDCYTCRNYSRAYLYHLDR... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | B2VHQ1 |
Q14HF2 | RS18_FRAT1 | 30S ribosomal protein S18 | Francisella | MSRRKVCRFTVEGVKEIDYKDVNKLKAYITETGKIVPSRVTGTSAKYQRQLATAIKRARFLALLPYCDRHFN | Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit. | Q14HF2 |
P12067 | LYSC1_PIG | 1,4-beta-N-acetylmuramidase C | Sus | KVYDRCEFARILKKSGMDGYRGVSLANWVCLAKWESDFNTKAINRNVGSTDYGIFQINSRYWCNDGKTPKAVNACHISCKVLLDDDLSQDIECAKRVVRDPQGIKAWVAWRTHCQNKDVSQYIRGCKL | Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. | P12067 |
Q46630 | AMSI_ERWAM | Probable low molecular weight protein-tyrosine-phosphatase AmsI | Erwinia | MINSILVVCIGNICRSPTGERLLKAALPERKIASAGLKAMVGGSADETASIVANEHGVSLQDHVAQQLTADMCRDSDLILVMEKKHIDLVCRINPSVRGKTMLFGHWINQQEIADPYKKSRDAFEAVYGVLENAAQKWVNALSR | May function as a phosphatase required for amylovoran (an exopolysaccharide that functions as a virulence factor) production. | Q46630 |
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