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- MULTIPLE ADENOCARCINOMAS (x2) WITH AN ACINAR PATTERN, SOLID PATTERN, MICROPAPILLARY PATTERN |
AND LEPIDIC PATTERN -- PATTERNS IN ORDER OF PREVALENCE. |
- MARGINS NEGATIVE FOR MALIGNANCY. |
- FOUR LYMPH NODES NEGATIVE FOR MALIGNANCY (0 POSITIVE/4). |
- LYMPHOVASCULAR INVASION PRESENT. |
- PLEASE SEE TUMOUR SUMMARY AND COMMENT. |
COMMENT: |
The histology of the two adenocarcinomas resemble one another and lymphovascular |
invasion is present. These findings favour that the smaller tumor is a metastasis, rather |
than a synchronous primary. |
</pre> |
===Micro=== |
<pre> |
Size (tissue): scant tissue (<0.5 cm). |
Gland formation: focal, poorly formed. |
Cell size: large. |
Cytoplasm: moderate-to-abundant, grey-eosinophilic. |
Nucleus location: eccentric. |
Nuclear pleomorphism: moderate. |
Nuclear moulding: absent. |
Nucleoli: present, prominent. |
Nuclear pseudoinclusions: present. |
</pre> |
<pre> |
Number of cores: 3. |
Length of cores (total): 2.0 cm. |
Gland formation: present. |
Cell size: large. |
Cytoplasm: moderate, grey-eosinophilic. |
Necrosis: none apparent. |
Mucin: none. |
Nucleus location: eccentric. |
Nuclear pleomorphism: moderate. |
Nuclear moulding: absent. |
Nuclear pseudoinclusions: absent. |
Nuclear shape/arrangment: cigar-like/pseudostratified. |
Nucleoli: present. |
</pre> |
====Mucinous==== |
The sections show cores with well-formed glands composed of foveolar-like columnar cells with a relatively bland cytomorphology. Mitotic activity is not readily apparent. A small amount of non-lesional lung parenchyma is present. |
===Lung cancer staging=== |
{{Main|Lung cancer staging}} |
==See also== |
*[[Lung tumours]]. |
*[[Adenocarcinoma]]. |
*[[Metastasis]]. |
*[[Lung carcinoma with ALK rearrangement]]. |
*[[SMARCA4-deficient adenocarcinoma of the lung]]. |
==References== |
{{Reflist|2}} |
==External links== |
*[http://www.cancer.org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-staging Lung cancer staging (cancer.org)]. |
*[http://www.nucmedresource.com/thoracic-nodal-stations.html Thoracic lymph node stations (nucmedresource.com)]. |
[[Category:Diagnosis]] |
[[Category:Lung tumours]] |
d9cab475231fc10fd79509b3beae6087ee5bf5e05a19ad1a1ad79eadd6905fe2 librepath-luad.txt |
{{ Infobox diagnosis |
| Name = {{PAGENAME}} |
| Image = Lung squamous carcinoma -- intermed mag.jpg |
| Width = |
| Caption = Squamous cell carcinoma of the lung. [[H&E stain]]. |
| Synonyms = squamous carcinoma of the lung |
| Micro = |
| Subtypes = |
| LMDDx = [[lung adenocarcinoma]], [[non-small cell lung carcinoma]], metastatic [[squamous cell carcinoma]], others |
| Stains = |
| IHC = [[p40]] +ve, [[p63]] +ve, [[TTF-1]] -ve, CK7 -ve |
| EM = |
| Molecular = |
| IF = |
| Gross = |
| Grossing = |
| Staging = [[lung cancer staging]] |
| Site = [[lung]] - see [[lung tumours]] |
| Assdx = |
| Syndromes = |
| Clinicalhx = [[smoking]] |
| Signs = |
| Symptoms = +/-hemoptysis |
| Prevalence = common |
| Bloodwork = serum calcium elevated |
| Rads = typically a mass assoc. with a large airway, +/-spiculated, +/-cavitation |
| Endoscopy = |
| Prognosis = usually poor |
| Other = |
| ClinDDx = other [[lung tumours]] - esp. [[small cell carcinoma of the lung]] |
| Tx = surgical resection if possible |
}} |
'''Squamous cell carcinoma of the lung''', also '''lung squamous cell carcinoma''', is a common [[cancer|malignant]] [[lung tumour]] that is associated with [[smoking]]. |
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