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*Uncommon.
*Part of the ''neuroblastic tumours'' group which includes:<ref name=pmid10421272>{{cite journal |author=Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B |title=Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee |journal=Cancer |...
**[[Ganglioneuroma]] (benign).
**Ganglioneuroblastoma (intermediate).
**[[Neuroblastoma]] (aggressive).
===Microscopic===
Features:
*Ganglion-like cells with a prominent nucleolus.
*Small undifferentiated cells with scant cytoplasm.
<gallery>
Image:Adrenal Ganglioneuroblastoma LP CTR.jpg|thumb|Adrenal Ganglioneuroblastoma - Low power (SKB)
Image:Adrenal Ganglioneuroblastoma MP CTR.jpg|thumb|Adrenal Ganglioneuroblastoma - Medium power (SKB)
Image:Adrenal Ganglioneuroblastoma HP CTR.jpg|thumb|Adrenal Ganglioneuroblastoma - High power (SKB)
Image:Adrenal Ganglioneuroblastoma HP3 CTR.jpg|thumb|Adrenal Ganglioneuroblastoma - High power (SKB)
Image:Adrenal Ganglioneuroblastoma HP2 CTR.jpg|thumb|Adrenal Ganglioneuroblastoma - High power (SKB)
</gallery>
Images:
*[http://path.upmc.edu/cases/case530.html Ganglioneuroblastoma - several images (upmc.edu)].
===IHC===
*NSE +ve -- small cells.
==Lesions of the sella turcica==
{{Main|Pituitary gland}}
Lesions of the sella turcica, the pituitary gland environs, is a topic for it self. The differential diagnosis for lesions in this area includes:
*[[Pituitary adenoma]].
*[[Craniopharyngioma]].
*[[Rathke cleft cyst]].
*[[Germ cell tumour]].
*[[Meningioma]].
*[[Pilomyxoid astrocytoma]] - in children.
==See also==
*[[Neuropathology]].
*[[Muscle biopsy]].
==References==
{{reflist|2}}
==External links==
*[http://www.neuropathologyweb.org/ Neuropathology (neuropathologyweb.org)].
*[http://www.pathology.vcu.edu/WirSelfInst/tumor-1.html Neuropathology Mini-Course (pathology.vcu.edu)].
*[http://www.pathology.vcu.edu/WirSelfInst/tumor-2.html Neuropathology Mini-Course (pathology.vcu.edu)].
[[Category:Neuropathology]]
1ae786132b80fb3e6b78b83b76314093965f84d5e5c1d3f49947f461378e349b librepath-neuropath-tumours.txt
'''Non-invasive breast carcinoma''' is a type of [[breast cancer]] and a common entity... since the introduction of radiologic breast screening.
Viewed simplistically, it can neatly be divided into the discussion of two entities:
#[[Ductal carcinoma in situ]] (DCIS).
#[[Lobular carcinoma in situ]] (LCIS).
Invasive breast cancer is dealt with in the article ''[[invasive breast cancer]]''. An introduction to the ''breast'' is found in the ''[[breast pathology]]'' article.
=Ductal neoplasia=
==Overview==
This category includes:
#[[Atypical ductal hyperplasia]] (ADH).
#[[Ductal carcinoma in situ]] (DCIS).
The difference between ADH and DCIS ''is'':
#The degree of '''nuclear atypia'''; high grade is DCIS.
#The '''extent'''; small lesions are ADH, large lesions (low-grade) DCIS.
==Is it ductal neoplasia?==
===FEHUT versus ADH versus DCIS===
*Breast duct lumen with too many cells; this is common problem is breast pathology.<ref name=Ref_BP167-8>{{Ref BP|167-8}}</ref>
**The general DDx for this scenario is: ''FEHUT'' versus ''ADH'' versus ''DCIS''.
Notes:
*FEHUT = florid epithelial hyperplasia of the usual type, [[AKA]] ''epithelial hyperplasia'' (EH).
*ADH = [[atypical ductal hyperplasia]].
*DCIS = [[ductal carcinoma in situ]].
====Tabular comparison - histomorphology====
Comparison of FEHUT, ADH and DCIS (memory device: ''CLEAN'' = cell spacing, luminal spaces, extent/size, arch., nuclei):
{| class="wikitable sortable"
! Morphology
! [[FEHUT]]
! [[ADH]]
! [[DCIS]]
|-
| '''Cell spacing'''
| varied, streaming
| focal uniformity
| uniform
|-
| '''Lumina'''
| slits/irregular spaces; <br>cells haphazardly <br>arranged around lumen
| irregular spaces, no slits
| circular "punched-out"; <br>cells side-by-side + <br>equally spaced @ interface
|-
| '''Extent'''
| usually lobulocentric
| limited extent
| extensive
|-
| '''Architecture'''
| irregular/swirling