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{{Main|Pituicytoma}}
==Spindle cell oncocytoma==
*Origin: Neurohypophysis or infundibulum.
*Benign clinical course - WHO grade I.
*Elongated bipolar, spindle cells.
*Fascicular or storiform growth patterns.
*EMA: patchy, S-100+/-ve, GFAP+/-ve, TTF1+ve.
*It is thought that Spindle cell oncocytomas and Granular cell tumors of the neurohypophysis are variants of Pituicyoma.<ref>{{Cite journal | last1 = Mete | first1 = O. | last2 = Lopes | first2 = MB. | last3 = Asa | first3 = SL. | title = Spindle cell oncocytomas and granular cell tumors of the pituitary are variants ...
==Granular cell tumor of the sellar region==
{{Main|Granular_cell_tumour}}
*Origin: Neurohypophysis or infundibulum.
*Benign clinical course - WHO grade I.
*Well circumscribed.
*Polygonal cells with abundant granular cytoplasm.
*CD68+ve, S-100+/-ve, GFAP+/-ve, TTF1+ve.
<gallery>
File:Granular_cell_tumor_pituitary.jpg | Granular cell tumor of the sellar region (HE).
</gallery>
==Autoimmune hypophysitis==
===General===
Features:<ref name=pmid18388197/>
*Rare.
*Autoantigens are unknown.
*May occur in pregnancy.
*May be misdiagnosed as a nonsecreting adenoma.
===Microscopic===
Features:<ref name=pmid18388197>{{cite journal |author=Tzou SC, Lupi I, Landek M, ''et al.'' |title=Autoimmune hypophysitis of SJL mice: clinical insights from a new animal model |journal=Endocrinology |volume=149 |issue=7 |pages=3461–9 |year=2008 |month=July |pmid=18388197 |pmc=2453094 |doi=10.1210/en.2007-1692 |url=}...
*Lymphocytic infiltration.
<gallery>
File:Lymphocytic_hypophysitis_CD3.jpg | Lymphocytic hypophysitis, CD3 IHC. (WC/jensflorian)
</gallery>
=See also=
*[[CNS cytopathology]].
*[[Neuropathology]].
*[[Brain tumours]].
=References=
{{reflist|2}}
=External links=
*[http://www.neuropathologyweb.org/ Neuropathology] - neuropathologyweb.org.
*[http://www.lab.anhb.uwa.edu.au/mb140/corepages/endocrines/endocrin.htm Endocrine histology (anhb.uwa.edu.au)].
[[Category:Neuropathology]]
fbfc11b83f334e34769b285f195f29b276504ea3a5e92df98700cfa84b1853cf librepath-pituitary-gland.txt
{{ Infobox diagnosis
| Name = {{PAGENAME}}
| Image = Schwannoma - Antoni A and B - very high mag.jpg
| Width =
| Caption = Schwannoma showing Antoni A and Antoni B areas. [[HPS stain]].
| Micro = Antoni A areas (cellular, fibrillary, polar, elongated), Antoni B area (pauci-cellular, loose microcystic tissue), Verocay bodies (paucinuclear area surrounded by nuclei), hyaline thickened [[blood vessel]]s, thick capsule.
+/-peripheral lymphoid cuff (esp. GI tract)
| Subtypes = conventional schwannoma, cellular schwannoma, plexiform schwannoma, melanotic schwannoma
| LMDDx = [[meningioma]], [[leiomyoma]], [[GIST]], [[intranodal palisaded myofibroblastoma]], [[MPNST]], [[neurofibroma]], [[biphenotypic sinonasal sarcoma]]
| Stains =
| IHC = S-100 +ve, EMA -ve, CD34 +ve
| EM =
| Molecular =
| IF =
| Gross =
| Grossing =
| Site = [[soft tissue lesions|soft tissue]] - [[peripheral nerve sheath tumours]]
| Assdx =
| Syndromes = [[neurofibromatosis type 2]], [[Carney complex]] (psammomatous melanotic schwannoma), schwannomatosis
| Clinicalhx =
| Signs =
| Symptoms =
| Prevalence = common
| Bloodwork =
| Rads =
| Endoscopy =
| Prognosis = good
| Other =
| ClinDDx = [[meningioma]] - esp. at [[cerebellopontine angle]]
}}
'''Schwannoma''' is a relatively common [[peripheral nerve sheath tumour]].
At the [[cerebellopontine angle|cerebellopontine (CP) angle]], they may be referred to as ''acoustic neuroma'' or ''vestibular schwannoma''.
==General==
*A common [[neuropathology]] [[CNS tumours|tumour]] that occasionally shows-up elsewhere.
*often encapsulated tumour of tissue surrounding a nerve.
**Axons adjacent to the tumour are normal... but may be compressed.
*May be a part of [[neurofibromatosis type 2]].
*Occurs at all ages.
==Macro==
*Usu. encapsulated.
*Cystic.
*Yellow patches on white surface.
**Variable lipidization.