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TITLE: Popliteal sciatic nerve block versus spinal anesthesia in hallux valgus surgery
ABSTRACT.BACKGROUND:
We compared clinical properties and patient satisfaction between spinal anesthesia and popliteal sciatic nerve block (PSNB) for hallux valgus surgery.
ABSTRACT.METHODS:
Forty patients undergoing hallux ... | Intervention: popliteal sciatic nerve block (PSNB) with 30 ml of 0.75% ropivacaine mixed with 10 ml of normal saline solution using a nerve stimulator
Comparator: spinal anesthesia with 2.5 ml of 0.5% bupivacaine
Outcome: The duration of the procedure, time from anesthesia induction until start of surgery, and surgery... | 1 | {"evidence_spans": [{"end": 10112, "start": 9931, "text": "2 groups (Table 1). The duration of the procedure, time from anesthesia induction until start of surgery, and surgery time were shorter in the spinal anesthesia group than in the P"}], "id": "1630", "pmcid": "3640164", "prompt_id": "1630", "split_group_id": "3... |
TITLE: Popliteal sciatic nerve block versus spinal anesthesia in hallux valgus surgery
ABSTRACT.BACKGROUND:
We compared clinical properties and patient satisfaction between spinal anesthesia and popliteal sciatic nerve block (PSNB) for hallux valgus surgery.
ABSTRACT.METHODS:
Forty patients undergoing hallux ... | Intervention: popliteal sciatic nerve block (PSNB) with 30 ml of 0.75% ropivacaine mixed with 10 ml of normal saline solution using a nerve stimulator
Comparator: spinal anesthesia with 2.5 ml of 0.5% bupivacaine
Outcome: he anesthesia-related side effects | 0 | {"evidence_spans": [{"end": 10449, "start": 10113, "text": "NB group (P < 0.01). The anesthesia-related side effects in the spinal anesthesia group were hypotension, bradycardia, shivering, vomiting, postoperative headache, and urinary retension, occurring in 15%, 10%, 5%, 5%, 10%, and 20% of patients, respectively. Th... |
TITLE: Alterations of consciousness and mystical-type experiences after acute LSD in humans
ABSTRACT.RATIONALE:
Lysergic acid diethylamide (LSD) is used recreationally and in clinical research. Acute mystical-type experiences that are acutely induced by hallucinogens are thought to contribute to their potential t... | Intervention: oral administration of 100 and 200 Î1⁄4g LSD
Comparator: placebo
Outcome: all of the scales | 1 | {"evidence_spans": [{"end": 23139, "start": 22947, "text": "re relatively small. LSD also produced vigilance reduction (VIR). LSD-induced changes on the 5D-ASC scale were significant compared with placebo for both doses and all of the scales, with the "}], "id": "1636", "pmcid": "5420386", "prompt_id": "1636", "split_g... |
TITLE: Alterations of consciousness and mystical-type experiences after acute LSD in humans
ABSTRACT.RATIONALE:
Lysergic acid diethylamide (LSD) is used recreationally and in clinical research. Acute mystical-type experiences that are acutely induced by hallucinogens are thought to contribute to their potential t... | Intervention: oral administration of 200 Î1⁄4g LSD
Comparator: 100 Î1⁄4g dose of LSD
Outcome: ratings of blissful state, insightfulness, and changed meaning of percepts | 1 | {"evidence_spans": [], "id": "1637", "pmcid": "5420386", "prompt_id": "1637", "split_group_id": "5420386", "votes": {"1": 1}} |
TITLE: Comparative effectiveness of two stabilization exercise positions on pain and functional disability of patients with low back pain
ABSTRACT:
The study investigated the effects of two stabilization exercise positions (prone and supine) on pain intensity (PI) and functional disability (FD) of patients with n... | Intervention: stabilization in prone and supine group (SIPS)
Comparator: baseline
Outcome: pain intensity and disability index | -1 | {"evidence_spans": [{"end": 16193, "start": 16037, "text": "easures of stabilization exercise in both prone and supine position group. The result revealed that there was a significant reduction between pretreatment a"}], "id": "1647", "pmcid": "5498096", "prompt_id": "1647", "split_group_id": "5498096", "votes": {"-1":... |
TITLE: Comparative effectiveness of two stabilization exercise positions on pain and functional disability of patients with low back pain
ABSTRACT:
The study investigated the effects of two stabilization exercise positions (prone and supine) on pain intensity (PI) and functional disability (FD) of patients with n... | Intervention: stabilization in prone (SIP)
Comparator: stabilization in supine (SIS) or prone and supine (SIPS) position group
Outcome: pain intensity and functional disability | 0 | {"evidence_spans": [{"end": 1406, "start": 1232, "text": "s. However, the result showed that there was no significant difference in the PI and FD at the 8th week (P>0.05) of the treatment sessions across the three groups when compar"}, {"end": 16473, "start": 16271, "text": "omparison of PI and DI among the SIP, SIS, a... |
TITLE: Bisoprolol in the treatment of chronic heart failure
ABSTRACT:
Bisoprolol fumarate is a highly selective beta-1 receptor blocker. Bisoprolol has been extensively studied in three large mortality trials in stable chronic heart failure (CHF) patients. The CIBIS trial enrolled 641 patients and demonstrated th... | Intervention: Bisoprolol
Comparator: placebo
Outcome: heart rate reduction and blood pressure reduction in CIBIS-II study | 1 | {"evidence_spans": [{"end": 10177, "start": 9929, "text": "mmarized in Table 1. Bisoprolol induced a significant heart rate reduction (of 9.8 \u00b1 14.7 beats/min), with a limited effect on blood pressure (systolic blood pressure reduction of 4.1 \u00b1 16.4 mmHg with bisoprolol but of 2.3 \u00b1 16.4 mmHg with placeb... |
TITLE: Bisoprolol in the treatment of chronic heart failure
ABSTRACT:
Bisoprolol fumarate is a highly selective beta-1 receptor blocker. Bisoprolol has been extensively studied in three large mortality trials in stable chronic heart failure (CHF) patients. The CIBIS trial enrolled 641 patients and demonstrated th... | Intervention: Bisoprolol
Comparator: placebo
Outcome: heart rate, hospital admission, sudden cardiac death, hospital admission for worsening heart failure in CIBIS-II study | -1 | {"evidence_spans": [{"end": 10751, "start": 10486, "text": "f 0.66 [0.54\u20130.81]). Bisoprolol significantly reduced cardiovascular mortality (HR: 0.71 [0.56\u20130.9]), sudden cardiac death (HR: 0.56 [0.39\u20130.80]), hospital admission (HR: 0.80 [0.71\u20130.91]), and hospital admission for worsening heart failure... |
TITLE: Bisoprolol in the treatment of chronic heart failure
ABSTRACT:
Bisoprolol fumarate is a highly selective beta-1 receptor blocker. Bisoprolol has been extensively studied in three large mortality trials in stable chronic heart failure (CHF) patients. The CIBIS trial enrolled 641 patients and demonstrated th... | Intervention: 10 mg/day for bisoprolol
Comparator: 20 mg/day for enalapril
Outcome: hospitalization hospitalization for worsening CHF in CIBIS-III | 0 | {"evidence_spans": [{"end": 15254, "start": 15011, "text": "[0.63\u20131.22], p = 0.44). There was a non-significant increase in the number of patients having a hospitalization for worsening CHF in the bisoprolol-first group compared with the enalapril-first group (63 vs 51 patients, respectively, HR = 1.25"}], "id": "... |
TITLE: Volumetric analysis of bone substitute material performance within the human sinus cavity of former head and neck cancer patients: A prospective, randomized clinical trial
ABSTRACT.BACKGROUND::
In numerous animal and human studies, it could be detected that in bone augmentation procedures, material's physi... | Intervention: Xenogeneic bone substitute material (Bio-Oss®, BO)
Comparator: Synthetic bone substitute material (NanoBone®, NB)
Outcome: Formation of new bone | 0 | {"evidence_spans": [{"end": 23119, "start": 22998, "text": "ifferent cellular reactions occurred in the implantation beds, no statistically significant difference in new bone format"}], "id": "1531", "pmcid": "5343624", "prompt_id": "1531", "split_group_id": "5343624", "votes": {"0": 1}} |
TITLE: Randomized controlled trial of oatmeal consumption versus noodle consumption on blood lipids of urban Chinese adults with hypercholesterolemia
ABSTRACT.BACKGROUND:
Cardiovascular disease (CVD) is the leading cause of death in China and worldwide. Whole grain oats can reduce risk of CVD by reducing total an... | Intervention: 100 grams of instant oat cereal
Comparator: 100 grams of wheat flour-based noodles
Outcome: total cholesterol and LDL-C | -1 | {"evidence_spans": [{"end": 1487, "start": 1374, "text": "vention. Total-, LDL-cholesterol and waist circumference decreased significantly in the oat group compared to the"}, {"end": 17925, "start": 17801, "text": "nd as change from baseline are presented in Table\r\n4. The oat group showed significant decreases in tot... |
TITLE: Ticagrelor vs. clopidogrel in patients with non-ST-elevation acute coronary syndrome with or without revascularization: results from the PLATO trial
ABSTRACT.AIMS:
The optimal platelet inhibition strategy for ACS patients managed without revascularization is unknown. We aimed to evaluate efficacy and safe... | Intervention: ticagrelor
Comparator: clopidogrel
Outcome: Cardiovascular death | -1 | {"evidence_spans": [{"end": 17171, "start": 17020, "text": "tary material online, Figure S1A). Cardiovascular death occurred less often in the ticagrelor group than in the clopidogrel group (3.7 vs. 4.9%; HR 0.7"}, {"end": 17437, "start": 17020, "text": "tary material online, Figure S1A). Cardiovascular death occurred ... |
TITLE: Ticagrelor vs. clopidogrel in patients with non-ST-elevation acute coronary syndrome with or without revascularization: results from the PLATO trial
ABSTRACT.AIMS:
The optimal platelet inhibition strategy for ACS patients managed without revascularization is unknown. We aimed to evaluate efficacy and safe... | Intervention: ticagrelor
Comparator: clopidogrel
Outcome: myocardial infarction | -1 | {"evidence_spans": [{"end": 17307, "start": 17020, "text": "tary material online, Figure S1A). Cardiovascular death occurred less often in the ticagrelor group than in the clopidogrel group (3.7 vs. 4.9%; HR 0.77; 95% CI = 0.64\u20130.93; P = 0.0070), and myocardial infarction was also less common with ticagrelor vs. c... |
TITLE: A Comparison of Two Delivery Modalities of a Mobile Phone-Based Assessment for Serious Mental Illness: Native Smartphone Application vs Text-Messaging Only Implementations
ABSTRACT.BACKGROUND:
Mobile phone–based assessment may represent a cost-effective and clinically effective method of monitoring psychot... | Intervention: completing 6 days of assessment (four sets of questions per day) with a native smartphone application
Comparator: completing 6 days of assessment (four sets of questions per day) with the SMS text-only implementation
Outcome: numbers of entries | 1 | {"evidence_spans": [{"end": 27643, "start": 27444, "text": "n the two delivery modalities (rho = 0.61, P=.002). When controlling for order effect, participants completed significantly greater numbers of entries on the native smartphone application when compar"}], "id": "1294", "pmcid": "3636800", "prompt_id": "1294", "... |
TITLE: The provision of written information and its effect on levels of pain and anxiety during electrodiagnostic studies: A randomised controlled trial
ABSTRACT.OBJECTIVE:
The provision of written information is a low-cost and readily available intervention that has been found to reduce pain and anxiety in a var... | Intervention: provided with written information about the electrodiagnostic testing
Comparator: control
Outcome: Overall scores for anxiety | -1 | {"evidence_spans": [{"end": 11619, "start": 11428, "text": "\r\n\r\nBODY.RESULTS.PRIMARY OUTCOMES:\r\nOverall scores for anxiety in the NCS cohort were found to be significantly lower (p = 0.04) in the intervention group (14.53\u00b12.44mm) than in the non-inter"}], "id": "1297", "pmcid": "5951568", "prompt_id": "1297"... |
TITLE: The provision of written information and its effect on levels of pain and anxiety during electrodiagnostic studies: A randomised controlled trial
ABSTRACT.OBJECTIVE:
The provision of written information is a low-cost and readily available intervention that has been found to reduce pain and anxiety in a var... | Intervention: provided with written information about the electrodiagnostic testing
Comparator: control
Outcome: levels of pain | 0 | {"evidence_spans": [{"end": 12238, "start": 12078, "text": "ere not provided with information. Overall pain scores between the intervention (20.91\u00b12.33mm) and non-intervention group (25.30\u00b12.44mm) in the NCS cohort did "}], "id": "1300", "pmcid": "5951568", "prompt_id": "1300", "split_group_id": "5951568", "... |
TITLE: Effectiveness of Comprehensive Health Education Combining Lifestyle Education and Hot Spa Bathing for Male White-Collar Employees: A Randomized Controlled Trial with 1-Year Follow-Up
ABSTRACT.BACKGROUND:
Physical activity is known to prevent obesity and metabolic syndrome in middle-aged and elderly people;... | Intervention: 2-hour program comprising comprehensive health education and hot spa bathing, offered once every 2 weeks, in addition to individualized programs once a week, for 24 weeks
Comparator: received only general health guidance.
Outcome: Rates of intervention attendance for the high and low attendance groups | 1 | {"evidence_spans": [{"end": 36820, "start": 36558, "text": "ne to follow-up (right P -value). Rates of intervention attendance for the high and low attendance groups were 57.0 \u00b1 22.3% and 8.3 \u00b1 9.4%, respectively, and were significantly different (P < 0.001). Participants who performed their individualized... |
TITLE: A controlled study of community-based exercise training in patients with moderate COPD
ABSTRACT.BACKGROUND:
The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study... | Intervention: 12-weeks of progressive endurance and strength training at a local health club
Comparator: continuation of unsupervised habitual physical activity
Outcome: TDI focal score | 1 | {"evidence_spans": [{"end": 15708, "start": 15547, "text": "ot the case with the control group. TDI focal score, shown in Figure 5, increased by 5.1 in the CBE group versus a decrease of 0.2 in the control group, indicati"}, {"end": 17935, "start": 17619, "text": "red clinically meaningful. Figure 5Mean TDI focal scor... |
TITLE:
ABSTRACT:
Recent evidence suggests that the fat mass and obesity-associated gene (FTO) genotype may interact with dietary intakes in relation to adiposity. We tested the effect of FTO variant on weight loss in response to 2-year diet interventions. FTO rs1558902 was genotyped in 742 obese adults who were ... | Intervention: assigned to the high-protein diet who carried the AA genotype of FTO rs1558902
Comparator: assigned to the high-protein diet without this genotype
Outcome: total fat, FM%, and percentage of trunk fat | -1 | {"evidence_spans": [{"end": 16049, "start": 15724, "text": "he four dietary compositions. We observed significant genotype-time interactions on changes in total fat, FM%, and percentage of trunk fat in response to the high-protein diet. When assigned to the high-protein diet, participants who carried the AA genotype ha... |
TITLE: Feto-maternal outcomes and Glycemic control in Metformin versus insulin treated Gestational Diabetics
ABSTRACT.OBJECTIVE::
To evaluate and compare feto-maternal outcomes and glycemic control in metformin versus insulin treated gestational diabetics.
ABSTRACT.METHODS::
The study was conducted in 2010- 2... | Intervention: oral metformin 500 mg TDS (Group-A)
Comparator: insulin 0.8-0.9 mg/kg/day in two divided doses subcutaneously (Group-B)
Outcome: fasting blood sugar (FBS) at term | 0 | {"evidence_spans": [{"end": 1163, "start": 1122, "text": "P=0.03). FBS at term was non-significant "}, {"end": 1269, "start": 1122, "text": "P=0.03). FBS at term was non-significant (p=0.079) and there was more number of cesarean sections due to feto-maternal disproportion in Group-B (28"}], "id": "1337", "pmcid": "567... |
TITLE: Feto-maternal outcomes and Glycemic control in Metformin versus insulin treated Gestational Diabetics
ABSTRACT.OBJECTIVE::
To evaluate and compare feto-maternal outcomes and glycemic control in metformin versus insulin treated gestational diabetics.
ABSTRACT.METHODS::
The study was conducted in 2010- 2... | Intervention: oral metformin 500 mg TDS (Group-A)
Comparator: insulin 0.8-0.9 mg/kg/day in two divided doses subcutaneously (Group-B)
Outcome: number of cesarean sections due to feto-maternal disproportion | -1 | {"evidence_spans": [{"end": 1269, "start": 1169, "text": "79) and there was more number of cesarean sections due to feto-maternal disproportion in Group-B (28"}], "id": "1338", "pmcid": "5673730", "prompt_id": "1338", "split_group_id": "5673730", "votes": {"-1": 1}} |
TITLE: Resistant starch lowers postprandial glucose and leptin in overweight adults consuming a moderate-to-high-fat diet: a randomized-controlled trial
ABSTRACT.BACKGROUND:
High-amylose maize resistant starch type 2 (HAM-RS2) stimulates gut-derived satiety peptides and reduces adiposity in animals. Human studies... | Intervention: muffins enriched with 30 g HAM-RS2
Comparator: muffins enriched with 0 g HAM-RS2 (control)
Outcome: peptide YY [PYY] | 1 | {"evidence_spans": [{"end": 1448, "start": 1280, "text": "ESULTS:\r\nAt baseline, total PYY concentrations were significantly higher 120 min following the consumption of study muffins in the HAM-RS2 group than control group (P ="}, {"end": 21535, "start": 20962, "text": "omarkers collected at each time point at the end... |
TITLE: Handwriting training in Parkinson’s disease: A trade-off between size, speed and fluency
ABSTRACT.BACKGROUND:
In previous work, we found that intensive amplitude training successfully improved micrographia in Parkinson's disease (PD). Handwriting abnormalities in PD also express themselves in stroke durati... | Intervention: Amplitude training
Comparator: Placebo
Outcome: Writing velocity | 0 | {"evidence_spans": [{"end": 1616, "start": 1554, "text": "ion period. In contrast, velocity remained unchanged throughou"}, {"end": 1616, "start": 1567, "text": "n contrast, velocity remained unchanged throughou"}], "id": "1220", "pmcid": "5741263", "prompt_id": "1220", "split_group_id": "5741263", "votes": {"0": 2}} |
TITLE: Effect of acupressure on fatigue in patients on hemodialysis
ABSTRACT.BACKGROUND::
Fatigue is considered as a major problem in hemodialysis patients and can impair their quality of life. The purpose of this study was to investigate the effectiveness of acupressure on fatigue in hemodialysis patients.
AB... | Intervention: Accupressure
Comparator: Placebo and routine unit care
Outcome: Total score of fatigue | -1 | {"evidence_spans": [{"end": 12063, "start": 11724, "text": " groups (P < 0.001). Post-hoc Duncan test showed that in the study group, total score of fatigue and score of fatigue in emotional, cognitive, and behavioral dimensions were significantly less than in the two groups of placebo and control after intervention (P... |
TITLE: Behavioural recovery after treatment for varicose veins
ABSTRACT.BACKGROUND:
The aim of this study was to assess behavioural recovery from the patient's perspective as a prespecified secondary outcome in a multicentre parallel‐group randomized clinical trial comparing ultrasound‐guided foam sclerotherapy (... | Intervention: Ultrasound‐guided foam sclerotherapy
Comparator: surgery
Outcome: Walking short distances (< 20 min ) without discomfort | 1 | {"evidence_spans": [], "id": "587", "pmcid": "4819709", "prompt_id": "587", "split_group_id": "4819709", "votes": {"1": 1}} |
TITLE: Intrathecal Morphine Plus General Anesthesia in Cardiac Surgery: Effects on Pulmonary Function, Postoperative Analgesia, and Plasma Morphine Concentration
ABSTRACT.OBJECTIVES::
To evaluate the effects of intrathecal morphine on pulmonary function, analgesia, and morphine plasma concentrations after cardiac... | Intervention: 400 ?g of intrathecal morphine followed by general anesthesia
Comparator: general anesthesia
Outcome: forced vital capacity (FVC), FEV1/FVC and PaO2/FiO2 ratio | 0 | {"evidence_spans": [{"end": 1609, "start": 1316, "text": ".RESULTS::\r\nBoth groups experienced reduced FVC postoperatively (3.24 L to 1.38 L in control group; 2.72 L to 1.18 L in morphine FEV1 (p=0.085), group), with no significant decreases observed between groups. The two groups also exhibited similar results for FE... |
TITLE: Clinical investigation of the acute effects of pomegranate juice on blood pressure and endothelial function in hypertensive individuals
ABSTRACT.BACKGROUND:
Pomegranate juice (PJ) is rich in bioactive phytochemicals with antioxidant, and anti-inflammatory and cardioprotective functions. The present trial i... | Intervention: Pomegranate juice (PJ)
Comparator: baseline
Outcome: C-reactive protein (CRP), intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), E-selectin and interleukin-6 (IL-6) | 0 | {"evidence_spans": [{"end": 1255, "start": 1099, "text": " 0.010). However, changes in FMD (20%) as well as circulating levels of CRP, ICAM-1, VCAM-1, E-selectin, and IL-6 did not reach statistical significance (P "}, {"end": 9157, "start": 8921, "text": "t (P = 0.172). In the same manner, there was no significant diff... |
TITLE: Comparison of paracetamol and fentanyl for pain relief during and after suction termination
ABSTRACT.OBJECTIVES::
To compare the combination of paracetamol (20 mg/kg) and propofol to fentanyl (1 μg/kg) and propofol in terms of providing adequate analgesia and a comparable recovery profile in suction termin... | Intervention: fentanyl (1 μg/kg) and propofol
Comparator: paracetamol (20 mg/kg) and propofol
Outcome: Diastolic blood pressures at 5 minutes | -1 | {"evidence_spans": [{"end": 1417, "start": 1233, "text": "p>0.05). In the fentanyl group, systolic blood pressures at 5, 10, 15, 20 minutes and diastolic blood pressure at 5 minutes and oxygen saturation at 5 minutes were significantly lower "}, {"end": 7651, "start": 7556, "text": "(p>0.05) (Figure 3). Diastolic blood... |
TITLE: The OnControl bone marrow biopsy technique is superior to the standard manual technique for hematologists-in-training: a prospective, randomized comparison
ABSTRACT:
The purpose of this study was to compare a novel bone marrow device with the standard marrow needle in a prospective, randomized study in a t... | Intervention: OnControl Bone Marrow Biopsy System
Comparator: Standard marrow needle
Outcome: Mean procedure time | -1 | {"evidence_spans": [{"end": 1155, "start": 1002, "text": "3. An objectively determined secondary endpoint; mean procedure time, skin-to-skin; also favored the OBM group (175 s) versus the SBM group (292 s), P<0."}, {"end": 10593, "start": 10452, "text": ".003 (Table 3). The mean procedure time, a secondary endpoint, wa... |
TITLE: The OnControl bone marrow biopsy technique is superior to the standard manual technique for hematologists-in-training: a prospective, randomized comparison
ABSTRACT:
The purpose of this study was to compare a novel bone marrow device with the standard marrow needle in a prospective, randomized study in a t... | Intervention: OnControl Bone Marrow Biopsy System
Comparator: Standard marrow needle
Outcome: Pain scores recorded by physicians | -1 | {"evidence_spans": [{"end": 11625, "start": 11462, "text": "l significance\r\n Other secondary endpoints which significantly favored the OBM group included the mean pain scores recorded by the fellows (P<0.002) and by the at"}, {"end": 11626, "start": 11462, "text": "l significance\r\n Other secondary endpoints which... |
TITLE: Thoracic epidural analgesia reduces myocardial injury in ischemic patients undergoing major abdominal cancer surgery
ABSTRACT.BACKGROUND AND OBJECTIVES:
Major abdominal cancer surgeries are associated with significant perioperative mortality and morbidity due to myocardial ischemia and infarction. This stu... | Intervention: General anesthesia plus epidural infusion (PCEA)
Comparator: General anesthesia plus intravenous analgesia (PCIA)
Outcome: Overall adverse cardiac events | -1 | {"evidence_spans": [{"end": 1718, "start": 1524, "text": "ESULTS:\r\nThere was a significant reduction in overall adverse cardiac events (myocardial injury, arrhythmias, angina, heart failure and nonfatal cardiac arrest) in PCEA group in comparison to PC"}, {"end": 2537, "start": 2336, "text": "ONCLUSION:\r\nPerioperat... |
TITLE: Thoracic epidural analgesia reduces myocardial injury in ischemic patients undergoing major abdominal cancer surgery
ABSTRACT.BACKGROUND AND OBJECTIVES:
Major abdominal cancer surgeries are associated with significant perioperative mortality and morbidity due to myocardial ischemia and infarction. This stu... | Intervention: General anesthesia plus epidural infusion (PCEA)
Comparator: General anesthesia plus intravenous analgesia (PCIA)
Outcome: Mean arterial pressure and heart rate during surgery | -1 | {"evidence_spans": [{"end": 2059, "start": 1850, "text": " points. Regarding perioperative hemodynamics, there was a significant reduction in intra-operative mean arterial pressure (MAP); and heart rate in PCEA group in comparison to PCIA group at most of measured ti"}, {"end": 2027, "start": 1886, "text": "odynamics, ... |
TITLE: Thoracic epidural analgesia reduces myocardial injury in ischemic patients undergoing major abdominal cancer surgery
ABSTRACT.BACKGROUND AND OBJECTIVES:
Major abdominal cancer surgeries are associated with significant perioperative mortality and morbidity due to myocardial ischemia and infarction. This stu... | Intervention: General anesthesia plus epidural infusion (PCEA)
Comparator: General anesthesia plus intravenous analgesia (PCIA)
Outcome: Troponin I levels | 1 | {"evidence_spans": [{"end": 12650, "start": 12522, "text": "comparison to PCIA group (Table 2). The level of troponin I was significantly higher in group PCEA in comparison to group PCIA a"}], "id": "1547", "pmcid": "5396972", "prompt_id": "1547", "split_group_id": "5396972", "votes": {"1": 2}} |
TITLE: High-Intensity Interval Training as an Efficacious Alternative to Moderate-Intensity Continuous Training for Adults with Prediabetes
ABSTRACT:
Aims. High-intensity interval training (HIIT) leads to improvements in various markers of cardiometabolic health but adherence to HIIT following a supervised labo... | Intervention: High-intensity interval training
Comparator: Traditional moderate-intensity continuous training
Outcome: Duration of vigorous physical activity weekly | 1 | {"evidence_spans": [{"end": 1152, "start": 979, "text": "5). Minutes spent in vigorous physical activity per week measured by accelerometer were higher in HIIT (24 \u00b1 18) as compared to MICT (11 \u00b1 10) at one-month follow-up (P = 0."}, {"end": 1171, "start": 979, "text": "5). Minutes spent in vigorous physical ... |
TITLE: The effect of different types of insoles or shoe modifications on medial loading of the knee in persons with medial knee osteoarthritis: a randomised trial
ABSTRACT.ABSTRACT:
Many conservative treatments exist for medial knee osteoarthritis (OA) which aims to reduce the external knee adduction moment (EKAM... | Intervention: barefoot condition
Comparator: control condition
Outcome: knee adduction angular impulse (KAAI) | -1 | {"evidence_spans": [{"end": 19207, "start": 18937, "text": "to the control condition. For the knee adduction angular impulse (KAAI), the barefoot condition and the two lateral wedge conditions were significantly different in comparison to the control condition (barefoot \u22124.3%, p = 0.023; typical wedge \u22127.95%,... |
TITLE: The effect of different types of insoles or shoe modifications on medial loading of the knee in persons with medial knee osteoarthritis: a randomised trial
ABSTRACT.ABSTRACT:
Many conservative treatments exist for medial knee osteoarthritis (OA) which aims to reduce the external knee adduction moment (EKAM... | Intervention: typical wedge
Comparator: control condition
Outcome: knee adduction angular impulse (KAAI) | -1 | {"evidence_spans": [{"end": 19207, "start": 18937, "text": "to the control condition. For the knee adduction angular impulse (KAAI), the barefoot condition and the two lateral wedge conditions were significantly different in comparison to the control condition (barefoot \u22124.3%, p = 0.023; typical wedge \u22127.95%,... |
TITLE: The effect of different types of insoles or shoe modifications on medial loading of the knee in persons with medial knee osteoarthritis: a randomised trial
ABSTRACT.ABSTRACT:
Many conservative treatments exist for medial knee osteoarthritis (OA) which aims to reduce the external knee adduction moment (EKAM... | Intervention: each of the two lateral wedge conditions
Comparator: barefoot walking
Outcome: early stance peak EKAM | 0 | {"evidence_spans": [{"end": 19440, "start": 19209, "text": "wedge \u22125.5%, p < 0.001). Pairwise comparisons (see supplementary material eTables S1\u20133) showed that there were no significant differences in the effects on the early stance peak in EKAM between each of the two lateral wedge condit"}], "id": "1680", ... |
TITLE: A Randomised Trial of Subcutaneous Intermittent Interleukin-2 without Antiretroviral Therapy in HIV-Infected Patients: The UK–Vanguard Study
ABSTRACT.OBJECTIVE::
The objective of the trial was to evaluate in a pilot setting the safety and efficacy of interleukin-2 (IL-2) therapy when used without concomita... | Intervention: IL-2 injections
Comparator: No treatment
Outcome: Change in CD4 T lymphocyte count at 24 weeks | 1 | {"evidence_spans": [{"end": 1555, "start": 1302, "text": "STRACT.RESULTS::\r\nArea under curve (AUC) for change in the mean CD4 T lymphocyte count through 24 wk was 129 cells/mm3 for those assigned IL-2 (both dose groups combined) and 13 cells/mm3 for control participants (95% CI for difference, 51.3\u2013181.2 cells"}... |
TITLE: The effect of different types of insoles or shoe modifications on medial loading of the knee in persons with medial knee osteoarthritis: a randomised trial
ABSTRACT.ABSTRACT:
Many conservative treatments exist for medial knee osteoarthritis (OA) which aims to reduce the external knee adduction moment (EKAM... | Intervention: barefoot condition
Comparator: mobility shoe
Outcome: early stance peak EKAM | -1 | {"evidence_spans": [{"end": 19601, "start": 19441, "text": "ons and barefoot walking. However, the early stance peak in EKAM in the barefoot condition was reduced significantly more than the mobility shoe (mean differenc"}], "id": "1681", "pmcid": "4737200", "prompt_id": "1681", "split_group_id": "4737200", "votes": {"... |
TITLE: A Randomised Trial of Subcutaneous Intermittent Interleukin-2 without Antiretroviral Therapy in HIV-Infected Patients: The UK–Vanguard Study
ABSTRACT.OBJECTIVE::
The objective of the trial was to evaluate in a pilot setting the safety and efficacy of interleukin-2 (IL-2) therapy when used without concomita... | Intervention: IL-2 injections
Comparator: No treatment
Outcome: Change in plasma HIV RNA | 0 | {"evidence_spans": [{"end": 1928, "start": 1773, "text": "ps, respectively. There were no significant differences between the IL-2 (0.13 log10 copies/ml) and control (0.09 log10 copies/ml) groups for AUC of change"}, {"end": 14815, "start": 14467, "text": "ange from Baseline \r\n\r\nBODY.RESULTS.VIROLOGIC MEASURES:\r\n... |
TITLE: The effect of different types of insoles or shoe modifications on medial loading of the knee in persons with medial knee osteoarthritis: a randomised trial
ABSTRACT.ABSTRACT:
Many conservative treatments exist for medial knee osteoarthritis (OA) which aims to reduce the external knee adduction moment (EKAM... | Intervention: mobility shoe
Comparator: control shoe
Outcome: walking speed | 1 | {"evidence_spans": [{"end": 20520, "start": 20402, "text": "lexion moment were seen. Compared with the control shoe, walking speed increased by 0.03m/s with the mobility shoe (9"}, {"end": 20703, "start": 20402, "text": "lexion moment were seen. Compared with the control shoe, walking speed increased by 0.03m/s with ... |
TITLE: L-lysine as adjunctive treatment in patients with schizophrenia: a single-blinded, randomized, cross-over pilot study
ABSTRACT.BACKGROUND:
Accumulating evidence suggests that the brain's nitric oxide (NO) signalling system may be involved in the pathophysiology of schizophrenia and could thus constitute a ... | Intervention: L-lysine
Comparator: Placebo
Outcome: L-lysine blood concentration | 1 | {"evidence_spans": [{"end": 1027, "start": 920, "text": "ESULTS:\r\nL-lysine treatment caused a significant increase in blood concentration of L-lysine and was well t"}, {"end": 14279, "start": 14005, "text": "F L-LYSINE WITHOUT INDUCING ADVERSE SIDE EFFECTS:\r\nAnalysis of L-lysine concentration in blood showed a sign... |
TITLE: L-lysine as adjunctive treatment in patients with schizophrenia: a single-blinded, randomized, cross-over pilot study
ABSTRACT.BACKGROUND:
Accumulating evidence suggests that the brain's nitric oxide (NO) signalling system may be involved in the pathophysiology of schizophrenia and could thus constitute a ... | Intervention: L-lysine
Comparator: Placebo
Outcome: Capacity to solve problems | 1 | {"evidence_spans": [{"end": 19036, "start": 18912, "text": "G CAPACITY WAS SIGNIFICANTLY IMPROVED DURING TREATMENT:\r\nProblem solving capacity and cognitive flexibility, as assessed by "}, {"end": 19171, "start": 18912, "text": "G CAPACITY WAS SIGNIFICANTLY IMPROVED DURING TREATMENT:\r\nProblem solving capacity and co... |
TITLE: A randomized controlled trial of an ambulatory approach versus the hospital-based approach in managing suspected obstructive sleep apnea syndrome
ABSTRACT:
Comparisons of home-based versus hospital-based approach in managing patients with suspected obstructive sleep apnoea syndrome(OSAS). A prospective, co... | Intervention: Home-based approach
Comparator: Hospital-based approach
Outcome: Waiting time | -1 | {"evidence_spans": [{"end": 1605, "start": 1181, "text": "1. The waiting time of patients with AHI \u2265 15/hr who were started on CPAP treatment from the first clinic consultation to the diagnostic sleep test, autoCPAP titration, and CPAP treatment was 189.6, 148.8 and 145.0 days shorter in group A than group B respe... |
TITLE: Randomized controlled trial of oatmeal consumption versus noodle consumption on blood lipids of urban Chinese adults with hypercholesterolemia
ABSTRACT.BACKGROUND:
Cardiovascular disease (CVD) is the leading cause of death in China and worldwide. Whole grain oats can reduce risk of CVD by reducing total an... | Intervention: 100 grams of instant oat cereal
Comparator: 100 grams of wheat flour-based noodles
Outcome: dietary fiber | 1 | {"evidence_spans": [{"end": 1373, "start": 1243, "text": "ESULTS:\r\nDietary fiber intake increased significantly in the oat group compared to the control group at the end of the 6-week inte"}, {"end": 14287, "start": 14158, "text": "e oat group than the control group (p=0.004). After 6 weeks of intervention, dietary f... |
TITLE: Effect of Improving Dietary Quality on Arterial Stiffness in Subjects with Type 1 and Type 2 Diabetes: A 12 Months Randomised Controlled Trial
ABSTRACT:
People with diabetes have accelerated arterial stiffening. The aim of this study was to determine the effect of increasing fruit, vegetable and dairy inta... | Intervention: Increased intake of fruits, vegetables and dairy
Comparator: Usual diet
Outcome: Central blood pressure (cBP) | 0 | {"evidence_spans": [{"end": 1777, "start": 1534, "text": "s. In the cohort with type 1 and type 2 diabetes, improving dietary quality by increasing consumption of fruit, vegetables and dairy did not improve cBP, AIx or cfPWV, compared with a control group continuing on their usual diet, after 12 mont"}], "id": "1570", ... |
TITLE: Randomized controlled trial of oatmeal consumption versus noodle consumption on blood lipids of urban Chinese adults with hypercholesterolemia
ABSTRACT.BACKGROUND:
Cardiovascular disease (CVD) is the leading cause of death in China and worldwide. Whole grain oats can reduce risk of CVD by reducing total an... | Intervention: 100 grams of instant oat cereal
Comparator: 100 grams of wheat flour-based noodles
Outcome: plasma glucose levels | 0 | {"evidence_spans": [{"end": 1722, "start": 1571, "text": "t group. There were no significant changes in blood pressure, other anthropometric or laboratory measures between the two groups at the end of the inte"}, {"end": 18238, "start": 18152, "text": "ized as a percentage change from baseline (Figure\r\n1). There were... |
TITLE: The effect of school meals with fatty fish on adolescents’ self-reported symptoms for mental health: FINS-TEENS - a randomized controlled intervention trial
ABSTRACT.ABSTRACT:
There is a growing body of evidence linking fish consumption and n-3 LCPUFAs to mental health. Still, the results from randomized t... | Intervention: Lunch meals with fatty fish (fish group)
Comparator: Lunch meals with meat (meat group)
Outcome: Symptom scores for emotional problems in high SDQ scorers | -1 | {"evidence_spans": [{"end": 22275, "start": 22038, "text": "TERVENTION ON HIGH SDQ-SCORERS AT BASELINE:\r\nIn the high-scorer sample, the fish group improved less in the symptom scores for emotional problems (p = 0.04) and total difficulties (p = 0.02) than the meat group. The difference remained s"}, {"end": 22371, "s... |
TITLE: Essential Amino Acid Enriched High-Protein Enteral Nutrition Modulates Insulin-Like Growth Factor-1 System Function in a Rat Model of Trauma-Hemorrhagic Shock
ABSTRACT.BACKGROUND:
Nutrition support for critically ill patients supplemented with additional modular protein may promote skeletal muscle protein ... | Intervention: T-HS/EAA
Comparator: T-HS/SE
Outcome: Gastrocnemius masses on day 4 and 6 | 1 | {"evidence_spans": [{"end": 18061, "start": 17916, "text": "this trend continued throughout the remainder of the study. In addition, the T-HS/EAA group exhibited a significant increase in gastrocnemius mas"}, {"end": 18060, "start": 17920, "text": " trend continued throughout the remainder of the study. In addition, th... |
TITLE: Essential Amino Acid Enriched High-Protein Enteral Nutrition Modulates Insulin-Like Growth Factor-1 System Function in a Rat Model of Trauma-Hemorrhagic Shock
ABSTRACT.BACKGROUND:
Nutrition support for critically ill patients supplemented with additional modular protein may promote skeletal muscle protein ... | Intervention: T-HS/Ctr
Comparator: PF group
Outcome: Levels of insulin | -1 | {"evidence_spans": [{"end": 21587, "start": 21430, "text": "roup (p<0.01).\r\n\r\nBODY.RESULTS.3. SERUM HORMONES (INSULIN AND CORTICOSTERONE) CONCENTRATIONS:\r\nInsulin levels in the T-HS/Ctr group were significantly decrea"}, {"end": 21600, "start": 21430, "text": "roup (p<0.01).\r\n\r\nBODY.RESULTS.3. SERUM HORMONES ... |
TITLE: Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
ABSTRACT:
The performance of recently introduced Surgical Stress Index (SSI), based on heart rate and photoplethysmography, was estimated during sevoflurane-fentanyl and isoflurane-fentanyl anesthesia during... | Intervention: Sevoflurane-fentanyl anesthesia
Comparator: Isoflurane-fentanyl anesthesia
Outcome: Surgical Stress Index values during surgery | 1 | {"evidence_spans": [{"end": 7002, "start": 6932, "text": "SOF groups but SSI values in SEVO group were higher than in ISOF group"}], "id": "1594", "pmcid": "2911596", "prompt_id": "1594", "split_group_id": "2911596", "votes": {"1": 1}} |
TITLE: Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
ABSTRACT:
The performance of recently introduced Surgical Stress Index (SSI), based on heart rate and photoplethysmography, was estimated during sevoflurane-fentanyl and isoflurane-fentanyl anesthesia during... | Intervention: Sevoflurane-fentanyl anesthesia
Comparator: Isoflurane-fentanyl anesthesia
Outcome: MAC and SE values before fentanyl boluses | 0 | {"evidence_spans": [{"end": 7188, "start": 7015, "text": "ry (Figure 2). MAC and SE values were similar in SEVO and ISOF groups before fentanyl boluses [0.74 \u00b1 0.12 versus 0.77 \u00b1 0.17, (P = .32) and 43.5 \u00b1 8.1 versus 45.2 \u00b1 8.3, (P"}, {"end": 7189, "start": 7015, "text": "ry (Figure 2). MAC and SE v... |
TITLE: Text Message Feedback to Support Mindfulness Practice in People With Depressive Symptoms: A Pilot Randomized Controlled Trial
ABSTRACT.BACKGROUND:
It has been shown that mindfulness practice can be helpful in preventing relapse from depression. However, practicing mindfulness regularly at home is often a c... | Intervention: Patients receiving text message–based feedback
Comparator: Patients not receiving text message assistance during follow-up
Outcome: PHQ-9 (depressive symptoms) scores | 0 | {"evidence_spans": [{"end": 28476, "start": 28219, "text": ". \r\n\r\nBODY.RESULTS.FEASIBILITY OF THE OUTCOME MEASURES:\r\nThe effects of the post-hoc assessment of mindfulness home practice (number and duration of exercises practiced) and the four selected outcome questionnaires (PHQ-9, PTQ, FFA, and SCS-D) yielded ne... |
TITLE: Use of Remifentanil and Alfentanil in Endotracheal Intubation: A Comparative Study
ABSTRACT.BACKGROUND::
Opioids, such as alfentanil, are used to facilitate endotracheal intubation without the use of neuromuscular blocking agents in patients undergoing elective surgery.
ABSTRACT.OBJECTIVES::
The goal o... | Intervention: Alfentanil
Comparator: Remifentanil
Outcome: Baseline demographic characteristics | 0 | {"evidence_spans": [{"end": 1400, "start": 1343, "text": ".RESULTS::\r\nThere were no demographic data differences be"}, {"end": 7096, "start": 6652, "text": " weight variables was normal. Demographic data (age, weight, and sex) were not significantly different between the two groups (Table 2). As shown in Table 2, gro... |
TITLE: Use of Remifentanil and Alfentanil in Endotracheal Intubation: A Comparative Study
ABSTRACT.BACKGROUND::
Opioids, such as alfentanil, are used to facilitate endotracheal intubation without the use of neuromuscular blocking agents in patients undergoing elective surgery.
ABSTRACT.OBJECTIVES::
The goal o... | Intervention: Alfentanil
Comparator: Remifentanil
Outcome: Jaw relaxation scores | 0 | {"evidence_spans": [{"end": 1565, "start": 1425, "text": ", and sex). Further, laryngoscopy, jaw relaxation, and limb movement scores were similar in the R and A groups and there were no significant"}, {"end": 1565, "start": 1434, "text": "). Further, laryngoscopy, jaw relaxation, and limb movement scores were similar ... |
TITLE: Critical reappraisal of embryo quality as a predictive parameter for pregnancy outcome: a pilot study
ABSTRACT:
Aim of the study: Pilot study to analyse the efficacy and embryo morphology using a new human embryo culture medium (GM501) versus the conventional used medium (ISM1). Methods: Over a four-month... | Intervention: New universal medium (GM501)
Comparator: Standard sequential culture medium ISM1
Outcome: Implantation rates | 0 | {"evidence_spans": [{"end": 904, "start": 756, "text": "s: We did not observe any differences between the ISM1 control group and GM501 study group with regard to fertilization, pregnancy, implantation rat"}, {"end": 940, "start": 756, "text": "s: We did not observe any differences between the ISM1 control group and GM5... |
TITLE: Critical reappraisal of embryo quality as a predictive parameter for pregnancy outcome: a pilot study
ABSTRACT:
Aim of the study: Pilot study to analyse the efficacy and embryo morphology using a new human embryo culture medium (GM501) versus the conventional used medium (ISM1). Methods: Over a four-month... | Intervention: New universal medium (GM501)
Comparator: Standard sequential culture medium ISM1
Outcome: Embryos with minimal fragmentation rate | 1 | {"evidence_spans": [{"end": 1063, "start": 941, "text": "n. The number of embryos with a minimal fragmentation rate (less than 30%) was significantly higher in the GM501 study gro"}, {"end": 15605, "start": 15444, "text": "etween the embryos transferred in the two groups. However, fewer nonfragmented embryos (25.4% vs.... |
TITLE: A comparison between subpleural patient-controlled analgesia by bupivacaine and intermittent analgesia in post-operative thoracotomy: A double-blind randomized clinical trial
ABSTRACT.BACKGROUND::
The efficacy of subpleural analgesia to reduce postoperative pain intensity in patients after lateral thoracot... | Intervention: subpleural patient-controlled analgesia (SPCA) (0.02 cc/kg/h of 0.5% bupivacaine)
Comparator: subpleural intermittent analgesia (SIA) (0.1cc/kg/6h of 0.5% bupivacaine)
Outcome: the incidence of adverse effects, such as pneumonia, atelectasis, bronchoscopic interventions, reintubations, hypersensitivity an... | 0 | {"evidence_spans": [{"end": 9292, "start": 9044, "text": "to the outcome data, there were no significant differences between the SP-treatment groups comparing the incidence of adverse effects, such as pneumonia, atelectasis, bronchoscopic interventions, reintubations, hypersensitivity and postoperative IC"}, {"end": 93... |
TITLE: A comparison between subpleural patient-controlled analgesia by bupivacaine and intermittent analgesia in post-operative thoracotomy: A double-blind randomized clinical trial
ABSTRACT.BACKGROUND::
The efficacy of subpleural analgesia to reduce postoperative pain intensity in patients after lateral thoracot... | Intervention: subpleural patient-controlled analgesia (SPCA) (0.02 cc/kg/h of 0.5% bupivacaine)
Comparator: subpleural intermittent analgesia (SIA) (0.1cc/kg/6h of 0.5% bupivacaine)
Outcome: VAS scores for 24 hr | 0 | {"evidence_spans": [{"end": 2013, "start": 1923, "text": "ddition, no significant difference was found in VAS scores at the three evaluated times (p"}, {"end": 10005, "start": 9829, "text": "ine 0.5% (Figure 1). When VAS scores were analyzed duration 24h, there were also no differences between the groups. There weren't... |
TITLE: A comparison between subpleural patient-controlled analgesia by bupivacaine and intermittent analgesia in post-operative thoracotomy: A double-blind randomized clinical trial
ABSTRACT.BACKGROUND::
The efficacy of subpleural analgesia to reduce postoperative pain intensity in patients after lateral thoracot... | Intervention: subpleural patient-controlled analgesia (SPCA) (0.02 cc/kg/h of 0.5% bupivacaine)
Comparator: subpleural intermittent analgesia (SIA) (0.1cc/kg/6h of 0.5% bupivacaine)
Outcome: VAS mean score at 16 h | -1 | {"evidence_spans": [{"end": 10509, "start": 10381, "text": "nd SIA duration 24h. VAS mean score at 16 h after the first SP instillation of bupivacaine 0.5% in SPCA group was significantly "}], "id": "1619", "pmcid": "3430047", "prompt_id": "1619", "split_group_id": "3430047", "votes": {"-1": 1}} |
TITLE: Promoting sexual abstinence intention among female university students: A quasi-experimental study
ABSTRACT.BACKGROUND::
The effectiveness of a theory-based educational intervention on intension for sexual abstinence among female university students was evaluated.
ABSTRACT.MATERIALS AND METHODS::
Femal... | Intervention: received educational intervention plus routine education
Comparator: received just routine education
Outcome: perceived susceptibility | 1 | {"evidence_spans": [{"end": 920, "start": 864, "text": "\u00b1 1.61), perceived susceptibility (14.05 \u00b1 1.51 vs. 12.3"}], "id": "1624", "pmcid": "3719224", "prompt_id": "1624", "split_group_id": "3719224", "votes": {"1": 1}} |
TITLE: Promoting sexual abstinence intention among female university students: A quasi-experimental study
ABSTRACT.BACKGROUND::
The effectiveness of a theory-based educational intervention on intension for sexual abstinence among female university students was evaluated.
ABSTRACT.MATERIALS AND METHODS::
Femal... | Intervention: received educational intervention plus routine education
Comparator: received just routine education
Outcome: perceived benefits | 1 | {"evidence_spans": [{"end": 1024, "start": 730, "text": " baseline, there were significant differences between the two groups in mean scores of the variables, knowledge (4.62 \u00b1 1.38 vs. 3.53 \u00b1 1.61), perceived susceptibility (14.05 \u00b1 1.51 vs. 12.37 \u00b1 2.11), and perceived benefits (28.41 \u00b1 2.14 ... |
TITLE: Popliteal sciatic nerve block versus spinal anesthesia in hallux valgus surgery
ABSTRACT.BACKGROUND:
We compared clinical properties and patient satisfaction between spinal anesthesia and popliteal sciatic nerve block (PSNB) for hallux valgus surgery.
ABSTRACT.METHODS:
Forty patients undergoing hallux ... | Intervention: popliteal sciatic nerve block (PSNB) with 30 ml of 0.75% ropivacaine mixed with 10 ml of normal saline solution using a nerve stimulator
Comparator: spinal anesthesia with 2.5 ml of 0.5% bupivacaine
Outcome: Incisional pain | 0 | {"evidence_spans": [{"end": 11258, "start": 11061, "text": "s in the PSNB group. Incisional pain was not reported in the spinal anesthesia group but was reported by 15% (3 cases) of patients in the PSNB group; however, these figures were not statistically s"}], "id": "1628", "pmcid": "3640164", "prompt_id": "1628", "sp... |
TITLE: Alterations of consciousness and mystical-type experiences after acute LSD in humans
ABSTRACT.RATIONALE:
Lysergic acid diethylamide (LSD) is used recreationally and in clinical research. Acute mystical-type experiences that are acutely induced by hallucinogens are thought to contribute to their potential t... | Intervention: oral administration of 100 and 200 Î1⁄4g LSD
Comparator: placebo
Outcome: overall ASC scale | 1 | {"evidence_spans": [], "id": "1635", "pmcid": "5420386", "prompt_id": "1635", "split_group_id": "5420386", "votes": {"1": 1}} |
TITLE: Magnetic Resonance Findings of Acute Severe Lower Back Pain
ABSTRACT.OBJECTIVE:
To determine abnormal MRI findings in adults hospitalized with acute severe axial LBP.
ABSTRACT.METHOD:
Sixty patients with back pain were divided into 3 groups consisting of 1) 23 adults with acute axial severe LBP who cou... | Intervention: adults with acute axial severe LBP who could not sit up or stand up for several days, but had not experienced previous back-related diseases or trauma (group A)
Comparator: adults who had been involved in a minor traffic accident, and had mild symptoms but not limited mobility (group B)
Outcome: differenc... | 1 | {"evidence_spans": [{"end": 1193, "start": 996, "text": " (4.4%). The findings of disc herniation, annular tear, HIZ, and LDD were more prevalent in A group than in B group (p<0.01). HIZ findings were more prevalent in A group than in group B or group C "}, {"end": 9261, "start": 9067, "text": "-5 and L5-S1 (Table 2). ... |
TITLE: Magnetic Resonance Findings of Acute Severe Lower Back Pain
ABSTRACT.OBJECTIVE:
To determine abnormal MRI findings in adults hospitalized with acute severe axial LBP.
ABSTRACT.METHOD:
Sixty patients with back pain were divided into 3 groups consisting of 1) 23 adults with acute axial severe LBP who cou... | Intervention: adults with acute axial severe LBP who could not sit up or stand up for several days, but had not experienced previous back-related diseases or trauma (group A)
Comparator: adults with LBP with radicular pain (group C)
Outcome: The proportion of HIZ incidence | 1 | {"evidence_spans": [{"end": 1193, "start": 1113, "text": "p<0.01). HIZ findings were more prevalent in A group than in group B or group C "}, {"end": 9439, "start": 9262, "text": "p B (p<0.05) (Table 3). The proportion of HIZ incidence was significantly higher in group A than in control group B, and in the patients wit... |
TITLE: Comparative effectiveness of two stabilization exercise positions on pain and functional disability of patients with low back pain
ABSTRACT:
The study investigated the effects of two stabilization exercise positions (prone and supine) on pain intensity (PI) and functional disability (FD) of patients with n... | Intervention: stabilization exercise in prone position group (SIP)
Comparator: baseline
Outcome: pain intensity and disability index | -1 | {"evidence_spans": [{"end": 15392, "start": 15235, "text": " outcome measures of stabilization exercise in prone position group. The result revealed that there was a significant reduction between pretreatment, 4th wee"}], "id": "1645", "pmcid": "5498096", "prompt_id": "1645", "split_group_id": "5498096", "votes": {"-1"... |
TITLE: Role of noninvasive ventilation in weaning from mechanical ventilation in patients of chronic obstructive pulmonary disease: An Indian experience
ABSTRACT.BACKGROUND::
Endotracheal intubation and mechanical ventilation (MV) are often needed in patients of chronic obstructive pulmonary disease (COPD) with a... | Intervention: Noninvasive ventilation (NIV)
Comparator: Pressure support ventilation (PSV)
Outcome: days spend in the ICU | 0 | {"evidence_spans": [{"end": 1526, "start": 1269, "text": "oth groups. No significant difference between the two groups in duration of MV (6.20 \u00b1 5.20 days vs. 7.47 \u00b1 6.38 days, P > 0.05), duration of weaning (35.17 \u00b1 16.98 and 47.05 \u00b1 20.98 hours, P > 0.05) or duration of ICU stay (8.47 \u00b1 4.79 ... |
TITLE: Role of noninvasive ventilation in weaning from mechanical ventilation in patients of chronic obstructive pulmonary disease: An Indian experience
ABSTRACT.BACKGROUND::
Endotracheal intubation and mechanical ventilation (MV) are often needed in patients of chronic obstructive pulmonary disease (COPD) with a... | Intervention: Noninvasive ventilation (NIV)
Comparator: Pressure support ventilation (PSV)
Outcome: Mortality at discharge from ICU | 0 | {"evidence_spans": [{"end": 1864, "start": 1664, "text": " NIV group. Lesser number of deaths in the NIV group at discharge from ICU (3 vs. 5 patients, respectively) and at 30 days (5 vs. 9 patients, respectively), it did not achieve statistical significance"}, {"end": 14280, "start": 13866, "text": "nt (P > 0.05, Tabl... |
TITLE: Role of noninvasive ventilation in weaning from mechanical ventilation in patients of chronic obstructive pulmonary disease: An Indian experience
ABSTRACT.BACKGROUND::
Endotracheal intubation and mechanical ventilation (MV) are often needed in patients of chronic obstructive pulmonary disease (COPD) with a... | Intervention: Noninvasive ventilation (NIV)
Comparator: Pressure support ventilation (PSV)
Outcome: duration of weaning | 0 | {"evidence_spans": [{"end": 1456, "start": 1269, "text": "oth groups. No significant difference between the two groups in duration of MV (6.20 \u00b1 5.20 days vs. 7.47 \u00b1 6.38 days, P > 0.05), duration of weaning (35.17 \u00b1 16.98 and 47.05 \u00b1 20.98 hour"}, {"end": 13666, "start": 13519, "text": "ly (P > 0.0... |
TITLE: Bisoprolol in the treatment of chronic heart failure
ABSTRACT:
Bisoprolol fumarate is a highly selective beta-1 receptor blocker. Bisoprolol has been extensively studied in three large mortality trials in stable chronic heart failure (CHF) patients. The CIBIS trial enrolled 641 patients and demonstrated th... | Intervention: bisoprolol
Comparator: placebo
Outcome: mortality in CIBIS trial | 0 | {"evidence_spans": [{"end": 7693, "start": 7439, "text": "rized in Table 1. During a mean duration of follow-up of 1.9 \u00b1 0.1 years, there were 120 deaths, 67 (20.9%) in the placebo group and 53 (16.6%) in the bisoprolol group (Figure 1). This difference was not statistically significant with a risk reduction of"},... |
TITLE: Bisoprolol in the treatment of chronic heart failure
ABSTRACT:
Bisoprolol fumarate is a highly selective beta-1 receptor blocker. Bisoprolol has been extensively studied in three large mortality trials in stable chronic heart failure (CHF) patients. The CIBIS trial enrolled 641 patients and demonstrated th... | Intervention: 10 mg/day for bisoprolol
Comparator: 20 mg/day for enalapril
Outcome: mortality in CIBIS-III | 0 | {"evidence_spans": [{"end": 15010, "start": 14825, "text": "alapril-first patients. There were fewer deaths in the bisoprolol-first group than in the enalapril-first group, but the difference was not statistically significant (65 vs 73, HR: 0.88"}], "id": "1657", "pmcid": "2291328", "prompt_id": "1657", "split_group_id... |
TITLE: Volumetric analysis of bone substitute material performance within the human sinus cavity of former head and neck cancer patients: A prospective, randomized clinical trial
ABSTRACT.BACKGROUND::
In numerous animal and human studies, it could be detected that in bone augmentation procedures, material's physi... | Intervention: Xenogeneic bone substitute material (Bio-Oss®, BO)
Comparator: Synthetic bone substitute material (NanoBone®, NB)
Outcome: Density changes | 0 | {"evidence_spans": [{"end": 23426, "start": 23270, "text": "s, the formation of new bone did not differ significantly.[1] Accordingly, the radiologically investigated volumetric and bone density changes in the prese"}, {"end": 25023, "start": 24937, "text": "assumption is in accordance with the results presented, as t... |
TITLE: Randomized controlled trial of oatmeal consumption versus noodle consumption on blood lipids of urban Chinese adults with hypercholesterolemia
ABSTRACT.BACKGROUND:
Cardiovascular disease (CVD) is the leading cause of death in China and worldwide. Whole grain oats can reduce risk of CVD by reducing total an... | Intervention: 100 grams of instant oat cereal
Comparator: 100 grams of wheat flour-based noodles
Outcome: Waist circumference | -1 | {"evidence_spans": [{"end": 1487, "start": 1402, "text": "erol and waist circumference decreased significantly in the oat group compared to the"}, {"end": 16570, "start": 16456, "text": "s change from baseline are presented in Table\r\n3. Waist circumference significantly decreased after 6weeks in the "}], "id": "1661"... |
TITLE: A Double-Blind Study on Acupuncture Sensations with Japanese Style of Acupuncture: Comparison between Penetrating and Placebo Needles
ABSTRACT:
To investigate the acupuncture sensations elicited by the Japanese style of acupuncture, penetrating acupuncture and skin-touch placebo needles were randomly admin... | Intervention: Acupuncture
Comparator: Placebo
Outcome: MASS index | 0 | {"evidence_spans": [{"end": 921, "start": 699, "text": "s. There were no significant differences in number of sensations elicited, MASS index, range of spreading, and intensity of needle pain for 5 mm penetration versus 1 mm skin press and 10 mm penetration versus 2 mm skin pre"}], "id": "1534", "pmcid": "5941723", "pr... |
TITLE: Cardiovascular outcomes during treatment with dabigatran: comprehensive analysis of individual subject data by treatment
ABSTRACT.BACKGROUND:
Dabigatran 150 mg twice daily was shown to be superior to warfarin in preventing stroke in subjects with nonvalvular atrial fibrillation (SPAF) in the RE-LY (Randomi... | Intervention: Dabigatran
Comparator: Warfarin
Outcome: Rates of myocardial infarction | 0 | {"evidence_spans": [{"end": 16193, "start": 15956, "text": "tran-treated subjects (Table 4). The rates of MI in RE-LY measured 0.82%, 0.81%, and 0.64% per year for the dabigatran 110 mg twice daily, dabigatran 150 mg twice daily, and warfarin treatment groups, respectively; the differences did no"}], "id": "1792", "pmc... |
TITLE: The analgesic efficacy of continuous presternal bupivacaine infusion through a single catheter after cardiac surgery
ABSTRACT.BACKGROUND::
Median sternotomy, sternal spreading, and sternal wiring are the main causes of pain during the early recovery phase following cardiac surgery.
ABSTRACT.AIM::
This ... | Intervention: Presternal catheter with continuous infusion of 5 mL/h bupivacaine 0.25% (Group B)
Comparator: Presternal catheter with continuous saline infusion (Group C)
Outcome: Wound infection incidence | 0 | {"evidence_spans": [{"end": 1754, "start": 1324, "text": "ACT.RESULTS::\r\nDuring the postoperative 48 h, there was marked reduction in morphine requirements in Group B compared to Group C, (8.6 \u00b1 0.94 mg vs. 18.83 \u00b1 3.4 mg respectively, P = 0.2), lower postoperative pain scores, shorter extubation time (117 ... |
TITLE: Preoperative Acute Normovolaemic Hemodilution (ANH) in combination with Hypotensive Epidural Anaesthesia (HEA) during knee arthroplasty surgery. No effect on transfusion rate. A randomized controlled trial [ISRCTN87597684]
ABSTRACT.BACKGROUND:
Hypotensive epidural anaesthesia (HEA) combines a high epidural... | Intervention: Preoperative acute normovolaemic hemodilution (ANH)
Comparator: No preoperative hemodilution (non-ANH)
Outcome: Surgery duration | 0 | {"evidence_spans": [{"end": 11702, "start": 11549, "text": "\u00b1 77 (non-ANH) (p = 0.56). Time used for anaesthesia (from patient enters the operating theatre to entering the recovery room) and duration of surgery wa"}], "id": "1805", "pmcid": "111193", "prompt_id": "1805", "split_group_id": "111193", "votes": {"0": ... |
TITLE: Preoperative Acute Normovolaemic Hemodilution (ANH) in combination with Hypotensive Epidural Anaesthesia (HEA) during knee arthroplasty surgery. No effect on transfusion rate. A randomized controlled trial [ISRCTN87597684]
ABSTRACT.BACKGROUND:
Hypotensive epidural anaesthesia (HEA) combines a high epidural... | Intervention: Preoperative acute normovolaemic hemodilution (ANH)
Comparator: No preoperative hemodilution (non-ANH)
Outcome: Hospital stay | 0 | {"evidence_spans": [{"end": 14770, "start": 14701, "text": "an (SD) * significance There was no difference in time spent in h"}], "id": "1808", "pmcid": "111193", "prompt_id": "1808", "split_group_id": "111193", "votes": {"0": 1}} |
TITLE: Vitamin A Supplementation at Birth Might Prime the Response to Subsequent Vitamin A Supplements in Girls. Three Year Follow-Up of a Randomized Trial
ABSTRACT.OBJECTIVES:
Within a randomised trial of neonatal vitamin A supplementation (VAS) in Guinea-Bissau, neonatal VAS did not affect overall infant mortal... | Intervention: Vitamin A supplementation (VAS)
Comparator: Placebo
Outcome: Baseline characteristics | 0 | {"evidence_spans": [{"end": 14978, "start": 14808, "text": "e.\r\n\r\nBODY.RESULTS.BASELINE CHARACTERISTICS:\r\nThere were no baseline differences between the children who had received neonatal VAS or placebo, continued to live in the s"}, {"end": 15178, "start": 14808, "text": "e.\r\n\r\nBODY.RESULTS.BASELINE CHARACTE... |
TITLE: Early biomarkers of brain injury and cerebral hypo- and hyperoxia in the SafeBoosC II trial
ABSTRACT.BACKGROUND:
The randomized clinical trial, SafeBoosC II, examined the effect of monitoring of cerebral oxygenation by near-infrared spectroscopy combined with a guideline on treatment when cerebral oxygenat... | Intervention: Cerebral NIRS monitoring in combination with an evidence based intervention guideline
Comparator: Blinded collection of NIRS values combined with treatment as usual
Outcome: Risk of severe brain injury or death | -1 | {"evidence_spans": [{"end": 22731, "start": 22356, "text": "correction for multiple comparisons. Correlation analyses of the following variables showed a significant correlation (p<0.05) between gestational age, birth weight, clinical chorioamnionitis, surfactant, mechanical ventilation, use of vasopressors, blood tr... |
TITLE: Automatic Tube Compensation versus Pressure Support Ventilation and Extubation Outcome in Children: A Randomized Controlled Study
ABSTRACT:
Background. Automatic tube compensation (ATC) has been developed to overcome the imposed work of breathing due to artificial airways during spontaneous breathing tri... | Intervention: Automatic tube compensation
Comparator: Pressure support ventilation
Outcome: Causes of reintubation | 0 | {"evidence_spans": [{"end": 12141, "start": 12040, "text": "psis and pneumonia (n = 4). There were no significant difference in the causes of reintubation betwee"}], "id": "1694", "pmcid": "3600348", "prompt_id": "1694", "split_group_id": "3600348", "votes": {"0": 1}} |
TITLE: Comparison of Functional Outcomes of Tibial Plateau Fractures Treated with Nonlocking and Locking Plate Fixations: A Nonrandomized Clinical Trial
ABSTRACT:
Fixation of tibial plateau fractures with plate has been widely used. This prospective study was planned to compare locking plate fixation of tibial pl... | Intervention: Locking plate fixation
Comparator: Nonlocking plate fixation
Outcome: Follow-up duration | 0 | {"evidence_spans": [{"end": 7763, "start": 7593, "text": "17 months). No difference was observed in the duration of follow-up between the locking plate and nonlocking plate groups (10.61 \u00b1 3.05 months versus 12.95 \u00b1 2.63 months,"}], "id": "1696", "pmcid": "4045368", "prompt_id": "1696", "split_group_id": "404... |
TITLE: Comparison of Functional Outcomes of Tibial Plateau Fractures Treated with Nonlocking and Locking Plate Fixations: A Nonrandomized Clinical Trial
ABSTRACT:
Fixation of tibial plateau fractures with plate has been widely used. This prospective study was planned to compare locking plate fixation of tibial pl... | Intervention: Locking plate fixation
Comparator: Nonlocking plate fixation
Outcome: Severity of the tibial plateau fractures | 0 | {"evidence_spans": [{"end": 9350, "start": 9142, "text": "r nonunion. No significant differences were found between the two groups in the severity of the tibial plateau fractures according to the Schatzker (P = 0.556) or AO (P = 0.257) classifications systems (Figur"}], "id": "1697", "pmcid": "4045368", "prompt_id": "1... |
TITLE: Randomized Controlled Study on Safety and Feasibility of Transfusion Trigger Score of Emergency Operations
ABSTRACT.BACKGROUND::
Due to the floating of the guideline, there is no evidence-based evaluation index on when to start the blood transfusion for patients with hemoglobin (Hb) level between 7 and 10 ... | Intervention: Peri-operative Transfusion Trigger Score of Emergency [POTTS-E] group
Comparator: Control group
Outcome: Hemoglobin at day 1 after surgery | -1 | {"evidence_spans": [{"end": 2167, "start": 2073, "text": "rtality. Only the POTTS-E group on the 1st postoperative day Hb was lower than group control, "}], "id": "1826", "pmcid": "4733710", "prompt_id": "1826", "split_group_id": "4733710", "votes": {"-1": 1}} |
TITLE: TREATMENT OF ACUTE AND TRANSIENT PSYCHOTIC DISORDERS WITH LOW AND HIGH DOSES OF ORAL HALOPERIDOL
ABSTRACT:
The apparent rationale for the popular use of high doses of neuroleptics in psychotic patients is to increase the degree and speed of therapeutic response .However, several recent reports have questio... | Intervention: High dose (20 mg/day) haloperidol
Comparator: Low dose (5 mg/day) haloperidol
Outcome: Improvement rate | 0 | {"evidence_spans": [{"end": 1076, "start": 985, "text": "s. Comparison of the improvement rate in both study groups revealed no significant differen"}], "id": "1831", "pmcid": "2967098", "prompt_id": "1831", "split_group_id": "2967098", "votes": {"0": 2}} |
TITLE: Three -Agent Preemptive Analgesia, Pregabalin-Acetaminophen-Naproxen, in Laparotomy for Cancer: A Randomized Clinical Trial
ABSTRACT.BACKGROUND:
Pain management after abdominal surgery is a critical issue in cancer patients undergoing laparotomy. Opioid analgesics commonly used postoperatively have signifi... | Intervention: Combination of pregabalin, acetaminophen, and naproxen (PAN) before the surgery
Comparator: No PAN administered before the surgery
Outcome: UPAT scores | -1 | {"evidence_spans": [{"end": 1580, "start": 1375, "text": "T.RESULTS:\r\nPatients in the PAN group had significantly lower UPAT scores at 0, 2, 4, 6, 12, 24 and 48 hours after the surgery than those in the control group (P = 0.008, 0.021, 0.008, 0.047, 0.004, 0.001,"}], "id": "1704", "pmcid": "5556332", "prompt_id": "17... |
TITLE: Three -Agent Preemptive Analgesia, Pregabalin-Acetaminophen-Naproxen, in Laparotomy for Cancer: A Randomized Clinical Trial
ABSTRACT.BACKGROUND:
Pain management after abdominal surgery is a critical issue in cancer patients undergoing laparotomy. Opioid analgesics commonly used postoperatively have signifi... | Intervention: Combination of pregabalin, acetaminophen, and naproxen (PAN) before the surgery
Comparator: No PAN administered before the surgery
Outcome: Consumption of morphine after the surgery | -1 | {"evidence_spans": [{"end": 1698, "start": 1581, "text": "and 0.001). The mean dose of postoperative morphine consumption in the PAN group was 37% less than the control group "}], "id": "1705", "pmcid": "5556332", "prompt_id": "1705", "split_group_id": "5556332", "votes": {"-1": 2}} |
TITLE: Effects of dexmedetomidine in combination with fentanyl-based intravenous patient-controlled analgesia on pain attenuation after open gastrectomy in comparison with conventional thoracic epidural and fentanyl-based intravenous patient-controlled analgesia
ABSTRACT:
Background: This study was investigated t... | Intervention: Dexmedetomidine plus fentanyl-based IV-PCA (dIV-PCA group) and Conventional thoracic epidural patient-controlled analgesia (E-PCA group)
Comparator: Fentanyl-based IV-PCA only (IV-PCA group)
Outcome: Need for additional analgesic rescues, number of bolus attempts, and bolus deliveries | -1 | {"evidence_spans": [{"end": 1777, "start": 1495, "text": "p. Patients in the dIV-PCA and E-PCA groups needed significantly fewer additional analgesic rescues between 6 and 24 hours after surgery, and had a significantly lower number of bolus attempts and bolus deliveries during the first 24 hours after surgery than tho... |
TITLE: Three -Agent Preemptive Analgesia, Pregabalin-Acetaminophen-Naproxen, in Laparotomy for Cancer: A Randomized Clinical Trial
ABSTRACT.BACKGROUND:
Pain management after abdominal surgery is a critical issue in cancer patients undergoing laparotomy. Opioid analgesics commonly used postoperatively have signifi... | Intervention: Combination of pregabalin, acetaminophen, and naproxen (PAN) before the surgery
Comparator: No PAN administered before the surgery
Outcome: Satisfaction with pain control as reported by surgeons | 1 | {"evidence_spans": [{"end": 11540, "start": 11418, "text": "g in the PAN and control groups, respectively). Surgeons reported more satisfaction with pain control in the medication gr"}, {"end": 11551, "start": 11418, "text": "g in the PAN and control groups, respectively). Surgeons reported more satisfaction with pain ... |
TITLE: Effects of dexmedetomidine in combination with fentanyl-based intravenous patient-controlled analgesia on pain attenuation after open gastrectomy in comparison with conventional thoracic epidural and fentanyl-based intravenous patient-controlled analgesia
ABSTRACT:
Background: This study was investigated t... | Intervention: Fentanyl-based IV-PCA only (IV-PCA group)
Comparator: Conventional thoracic epidural patient-controlled analgesia (E-PCA group)
Outcome: Total dose of ephedrine | -1 | {"evidence_spans": [{"end": 15307, "start": 15146, "text": "< 0.001, respectively). In addition, the patients in the E-PCA group required more ephedrine than those in the IV-PCA group (8.4 \u00b1 9.1 vs. 4.0 \u00b1 4.8 \u03bcg; Bonferro"}, {"end": 15307, "start": 15159, "text": "ectively). In addition, the patients in ... |
TITLE: Neural Habituation to Painful Stimuli Is Modulated by Dopamine: Evidence from a Pharmacological fMRI Study
ABSTRACT:
In constantly changing environments, it is crucial to adaptively respond to threatening events. In particular, painful stimuli are not only processed in terms of their absolute intensity, bu... | Intervention: Haloperidol
Comparator: Placebo
Outcome: Stimulation outcomes | 0 | {"evidence_spans": [{"end": 28344, "start": 27958, "text": " is summarized in Table 5. A 2 \u00d7 3 \u00d7 2 ANOVA revealed a significant main effect of context (F(1.79,34.07) = 75.65; p < 0.0001) and a significant interaction between context and stimulation outcome (F(1.34 25.54) = 4.09; p = 0.043), but no interaction... |
TITLE: Neural Habituation to Painful Stimuli Is Modulated by Dopamine: Evidence from a Pharmacological fMRI Study
ABSTRACT:
In constantly changing environments, it is crucial to adaptively respond to threatening events. In particular, painful stimuli are not only processed in terms of their absolute intensity, bu... | Intervention: Haloperidol
Comparator: Placebo
Outcome: Brain regions with adaptive coding | 0 | {"evidence_spans": [{"end": 1334, "start": 1266, "text": "t. Finally, there were no adaptive coding effects in any brain regio"}, {"end": 33395, "start": 32907, "text": "ion\" section). In the next step, we identified brain regions with adaptively coded responses to stimulation outcome irrespective of drug treatment (... |
TITLE: Pentoxifylline Plus Prednisolone versus Pentoxifylline Only for Severe Alcoholic Hepatitis: A Randomized Controlled Clinical Trial
ABSTRACT.BACKGROUND::
Prednisolone and pentoxifylline (PTX) have been shown to be individually useful in severe alcoholic hepatitis with Maddrey discriminant function (MDF) sco... | Intervention: Pentoxifylline plus prednisolone (Group 2)
Comparator: Pentoxifylline alone (Group 1)
Outcome: Rate of morbidity and complications | 0 | {"evidence_spans": [{"end": 15252, "start": 15180, "text": "succumbed to the disease. The morbidity/complication profiles among the"}, {"end": 15263, "start": 15180, "text": "succumbed to the disease. The morbidity/complication profiles among the two groups"}], "id": "1759", "pmcid": "4199180", "prompt_id": "1759", "... |
TITLE: Vitamin A status and body pool size of infants before and after consuming fortified home-based complementary foods
ABSTRACT.BACKGROUND:
Home fortification using sachets of micronutrient powder (e.g. "Sprinkles") is a food-based approach offering an alternative to high dose vitamin A (VA) supplements for in... | Intervention: Sachets of "Sprinkles� with vitamin A
Comparator: Sachets of "Sprinkles� without vitamin A
Outcome: Total body stores of vitamin A | 0 | {"evidence_spans": [{"end": 1400, "start": 1269, "text": "tively. After intervention, total body stores (TBS) and liver retinol concentrations did not differ between intervention and contro"}], "id": "1767", "pmcid": "4780150", "prompt_id": "1767", "split_group_id": "4780150", "votes": {"0": 2}} |
TITLE: Vitamin A status and body pool size of infants before and after consuming fortified home-based complementary foods
ABSTRACT.BACKGROUND:
Home fortification using sachets of micronutrient powder (e.g. "Sprinkles") is a food-based approach offering an alternative to high dose vitamin A (VA) supplements for in... | Intervention: Sachets of "Sprinkles� with vitamin A
Comparator: Sachets of "Sprinkles� without vitamin A
Outcome: Vitamin A concentrations in the liver | 0 | {"evidence_spans": [{"end": 1400, "start": 1268, "text": "ctively. After intervention, total body stores (TBS) and liver retinol concentrations did not differ between intervention and contro"}, {"end": 1546, "start": 1268, "text": "ctively. After intervention, total body stores (TBS) and liver retinol concentrations di... |
TITLE: Dexmedetomidine versus esmolol to attenuate the hemodynamic response to laryngoscopy and tracheal intubation: A randomized double-blind clinical study
ABSTRACT.CONTEXT::
Sympathoadrenal response to laryngoscopy and tracheal intubation manifests as transient, but distinct tachycardia and hypertension.
AB... | Intervention: Placebo (Group C) and esmolol (Group E)
Comparator: Dexmedetomidine (Group D)
Outcome: Mean systolic arterial pressure after intubation | 1 | {"evidence_spans": [{"end": 1655, "start": 1442, "text": "STRACT.RESULTS::\r\nThe mean arterial pressure was significantly increased in patients receiving placebo (P < 0.0001) and esmolol (P < 0.0001) after laryngoscopy and intubation compared with baseline value and Group"}, {"end": 10362, "start": 10192, "text": " ra... |
TITLE: Dexmedetomidine versus esmolol to attenuate the hemodynamic response to laryngoscopy and tracheal intubation: A randomized double-blind clinical study
ABSTRACT.CONTEXT::
Sympathoadrenal response to laryngoscopy and tracheal intubation manifests as transient, but distinct tachycardia and hypertension.
AB... | Intervention: Placebo (Group C) and esmolol (Group E)
Comparator: Dexmedetomidine (Group D)
Outcome: Mean diastolic arterial pressure after intubation | 1 | {"evidence_spans": [{"end": 10714, "start": 10613, "text": "(mm of Hg) in the three groups The DAP levels in Group D were significantly lower than Groups C and"}], "id": "1779", "pmcid": "4137650", "prompt_id": "1779", "split_group_id": "4137650", "votes": {"1": 2}} |
TITLE: Dexmedetomidine versus esmolol to attenuate the hemodynamic response to laryngoscopy and tracheal intubation: A randomized double-blind clinical study
ABSTRACT.CONTEXT::
Sympathoadrenal response to laryngoscopy and tracheal intubation manifests as transient, but distinct tachycardia and hypertension.
AB... | Intervention: Placebo (Group C) and esmolol (Group E)
Comparator: Dexmedetomidine (Group D)
Outcome: Mean rate pressure product up to 15 min after intubation | 1 | {"evidence_spans": [{"end": 12161, "start": 11659, "text": " of HR and SAP (RPP = HR \u00d7 SAP). In our study the RPP during intubation revealed a highly significant increase in Group C (76.5%, P < 0.0001) and significant increase in Group E (49%, P < 0.001), whereas the increase was insignificant in Group D (16%, P >... |
TITLE: Effects of Substituting Soybean Meal for Sunflower Cake in the Diet on the Growth and Carcass Traits of Crossbred Boer Goat Kids
ABSTRACT:
The present study was conducted to determine the best level of substitution of soybean meal by sunflower cake in diets for kids through the evaluation of quantitative c... | Intervention: sunflower cake
Comparator: soybean meal
Outcome: The commercial cuts and yields and goats | 0 | {"evidence_spans": [{"end": 9102, "start": 8969, "text": "DISCUSSION:\r\nThe substitution of soybean meal by sunflower cake in the diet of goats did not affect (p>0.05) body weight at slaughter"}, {"end": 12212, "start": 12088, "text": "me pattern. The commercial cuts and yields were not influenced (p>0.05) by the sub... |
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