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Back up measured InterPro API coverage, sampled inputs and cached responses
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{
"checked_utc": "2026-10-01T18:17:21.393082+00:00",
"endpoint": "https://www.ebi.ac.uk/interpro/matches/api/matches",
"seed": 20261001,
"unique_queries": 6688,
"cohorts": {
"frozen_training_endpoint_pool": {
"population": 899427,
"source": "/mnt/disk3/zn10/gpbridge_enzyme_dataset/motif_scratch_20260926/training_index/union_cluster_input.fasta",
"queried": 3000,
"successful": 3000,
"technical_errors": 0,
"counts": {
"found": 3000,
"any_match": 3000,
"traditional_match": 3000,
"pfam_match": 2981,
"selected_traditional_match": 2993,
"selected_site_annotation": 2486,
"selected_binding_site_annotation": 1848,
"neural_only": 0
},
"fractions": {
"found": 1.0,
"any_match": 1.0,
"traditional_match": 1.0,
"pfam_match": 0.9936666666666667,
"selected_traditional_match": 0.9976666666666667,
"selected_site_annotation": 0.8286666666666667,
"selected_binding_site_annotation": 0.616,
"neural_only": 0.0
},
"api_found_wilson95": [
0.9987211512746742,
1.0000000000000002
]
},
"accepted_filter_study_panel": {
"population": 22791,
"queried": 3000,
"successful": 3000,
"technical_errors": 0,
"counts": {
"found": 3000,
"any_match": 2999,
"traditional_match": 2997,
"pfam_match": 2928,
"selected_traditional_match": 2968,
"selected_site_annotation": 2309,
"selected_binding_site_annotation": 1604,
"neural_only": 2
},
"fractions": {
"found": 1.0,
"any_match": 0.9996666666666667,
"traditional_match": 0.999,
"pfam_match": 0.976,
"selected_traditional_match": 0.9893333333333333,
"selected_site_annotation": 0.7696666666666667,
"selected_binding_site_annotation": 0.5346666666666666,
"neural_only": 0.0006666666666666666
},
"api_found_wilson95": [
0.9987211512746742,
1.0000000000000002
]
},
"study_references": {
"population": 692,
"queried": 692,
"successful": 692,
"technical_errors": 0,
"counts": {
"found": 692,
"any_match": 692,
"traditional_match": 692,
"pfam_match": 685,
"selected_traditional_match": 691,
"selected_site_annotation": 590,
"selected_binding_site_annotation": 422,
"neural_only": 0
},
"fractions": {
"found": 1.0,
"any_match": 1.0,
"traditional_match": 1.0,
"pfam_match": 0.9898843930635838,
"selected_traditional_match": 0.9985549132947977,
"selected_site_annotation": 0.8526011560693642,
"selected_binding_site_annotation": 0.6098265895953757,
"neural_only": 0.0
},
"api_found_wilson95": [
0.9944794050828696,
1.0
]
}
},
"limitations": [
"Random-sequence samples are estimates, not a census of the full 483-shard dataset.",
"API presence does not imply a named ligand label or complete ligand-set coverage.",
"InterPro-N, SignalP, DeepTMHMM and TMbed are excluded from traditional signature counts."
],
"library_versions": {
"CATH-FunFam:4.3.0": 5136,
"CATH-Gene3D:4.3.0": 12067,
"CDD:3.21": 4958,
"COILS:2.2.1": 431,
"HAMAP:2026_01": 1347,
"MobiDB-lite:4.0": 1126,
"NCBIFAM:20.0": 4476,
"PANTHER:19.0": 6444,
"PIRSF:3.10": 1460,
"PIRSR:2025_05": 30601,
"PRINTS:42.0": 2412,
"PROSITE patterns:2026_01": 4040,
"PROSITE profiles:2026_01": 2759,
"Pfam:38.2": 10290,
"Phobius:1.01": 7914,
"SFLD:4": 919,
"SMART:9.0": 2314,
"SUPERFAMILY:1.75": 9833
}
}