metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
cellpopage
CellPopAge is an elastic-net DNA-methylation clock using 42 selected CpGs to predict passage-based age of serially cultured adult primary human fibroblast populations and screen compounds that decelerate this measure.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | cell-population passage age |
| Species | Homo sapiens |
| Tissue | cultured fibroblasts |
| Data type | DNA methylation |
| Model type | elastic net regression |
| Year | 2024 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["cellpopage"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Lujan, Celia, et al. "An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo." Genome Medicine 16 (2024): 85.