metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
dnamfili
Epigenetic frailty risk score (eFRS), a weighted 20-CpG whole-blood DNA-methylation score selected by LASSO from replicated frailty-associated loci.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | frailty risk |
| Species | Homo sapiens |
| Tissue | whole blood |
| Data type | DNA methylation |
| Model type | LASSO regression |
| Year | 2022 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["dnamfili"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Li, X. et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nature Communications 13, 5269 (2022).