| library_name: pyaging | |
| tags: | |
| - pyaging | |
| - aging-clock | |
| - biology | |
| - dna-methylation | |
| # dnamstress | |
| Whole-blood methylation score (MS stress) derived as a 211-CpG proxy for a composite of 13 stress-related measures. | |
| Model weights retain the original authors' terms; the pyaging software license does not relicense them. | |
| | | | | |
| |---|---| | |
| | **Predicts** | stress exposure | | |
| | **Species** | Homo sapiens | | |
| | **Tissue** | whole blood | | |
| | **Data type** | DNA methylation | | |
| | **Model type** | bootstrap-stabilized elastic net regression | | |
| | **Year** | 2023 | | |
| ## Use with pyaging | |
| ```python | |
| import pyaging as pya | |
| pya.pred.predict_age(adata, ["dnamstress"]) | |
| ``` | |
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). | |
| ## Citation | |
| Jung, J., et al. “Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use Disorder.” Biological Psychiatry 93(4): 331–341 (2023). | |
| https://doi.org/10.1016/j.biopsych.2022.06.036 | |