epitoc1 / README.md
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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

epitoc1

Relative mitotic-age score equal to the mean beta value across 385 polycomb-target promoter CpGs; it is not an absolute division count.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts mitotic age
Species Homo sapiens
Tissue multi-tissue, whole blood
Data type DNA methylation
Model type mean methylation aggregation
Year 2016

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["epitoc1"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Yang, Zhen, et al. "Correlation of an epigenetic mitotic clock with cancer risk." Genome Biology 17 (2016): 205.

https://doi.org/10.1186/s13059-016-1064-3