hepatoxu / README.md
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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

hepatoxu

Ten-marker plasma cfDNA methylation logistic model producing the combined HCC diagnosis score (cd-score); this packaged model does not implement the separate eight-marker prognosis score.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts hepatocellular carcinoma
Species Homo sapiens
Tissue plasma cell-free DNA
Data type DNA methylation
Model type feature-selected logistic regression
Year 2017

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["hepatoxu"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Xu, R.-H., et al. “Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma.” Nature Materials 16: 1155–1161 (2017).

https://doi.org/10.1038/nmat4997