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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

mammalian2

Universal pan-mammalian clock 2 fits relative age (age divided by species maximum lifespan) and the author inverse transformation returns species-adjusted chronological age in years.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts chronological age
Species multiple species
Tissue multi-tissue
Data type DNA methylation
Model type elastic net regression
Year 2023

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["mammalian2"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Lu, A. T., et al. "Universal DNA methylation age across mammalian tissues." Nature Aging 3.9 (2023): 1144-1166.

https://doi.org/10.1038/s43587-023-00462-6