| library_name: pyaging | |
| tags: | |
| - pyaging | |
| - aging-clock | |
| - biology | |
| - dna-methylation | |
| # mammalian2 | |
| Universal pan-mammalian clock 2 fits relative age (age divided by species maximum lifespan) and the author inverse transformation returns species-adjusted chronological age in years. | |
| Model weights retain the original authors' terms; the pyaging software license does not relicense them. | |
| | | | | |
| |---|---| | |
| | **Predicts** | chronological age | | |
| | **Species** | multiple species | | |
| | **Tissue** | multi-tissue | | |
| | **Data type** | DNA methylation | | |
| | **Model type** | elastic net regression | | |
| | **Year** | 2023 | | |
| ## Use with pyaging | |
| ```python | |
| import pyaging as pya | |
| pya.pred.predict_age(adata, ["mammalian2"]) | |
| ``` | |
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). | |
| ## Citation | |
| Lu, A. T., et al. "Universal DNA methylation age across mammalian tissues." Nature Aging 3.9 (2023): 1144-1166. | |
| https://doi.org/10.1038/s43587-023-00462-6 | |