metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
retroelementagev2
Composite Retroelement-Age V2 extends the retroelement annotation to CpGs compatible across EPIC v1.0 and v2.0 and was trained by 10-fold-cross-validated elastic net.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | chronological age |
| Species | Homo sapiens |
| Tissue | whole blood |
| Data type | DNA methylation |
| Model type | elastic net regression |
| Year | 2024 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["retroelementagev2"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Ndhlovu, Lishomwa C., et al. "Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements." Aging Cell 23 (2024): e14288.