plaque-analysis / README.md
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---
license: mit
language:
- en
library_name: pytorch
tags:
- medical-imaging
- coronary-artery-segmentation
- cardiac-ct
- nnunet
- imagecas
---
# Coronary Artery Segmentation (nnU-Net)
nnU-Net trained on ImageCAS dataset for coronary artery tree segmentation in cardiac CT angiography (CCTA).
## Model Details
- **Architecture**: nnU-Net v2 (3D Residual-Encoder, full resolution)
- **Input**: 3D CCTA volumes (NIfTI format)
- **Output**: Coronary artery voxel-wise segmentation
## Training
- **Dataset**: ImageCAS (~1,000 CCTA scans)
- **Split**: Official ImageCAS split (train/val/test)
- **Fold**: fold_0 (best validation performance)
## Downstream Pipeline
Part of multi-stage clinical analysis system:
1. **Stage 1** (this model): Coronary segmentation
2. **Stage 2**: Plaque classification (HU-threshold: calcified/non-calcified/LRNC)
3. **Stage 3**: 3D plaque map reconstruction
4. **Stage 4**: FFR estimation (research prototype, CFD-capable)
5. **Stage 5**: Clinical review app with 3D visualization & curved MPR
## Real Case Examples
Outputs included demonstrate:
- Coronary mesh with plaque composition color-coding (phase4_job_case1_v2)
- Curved MPR for interventionalist visualization
- Diameter profiling, QC gates, comprehensive reports
## Citation
ImageCAS: Huo et al., "Towards Robust Coronary Artery Segmentation in CCTA" (2021)
nnU-Net: Isensee et al., "nnU-Net: Self-configuring method for deep learning-based biomedical image segmentation" (2021)
## License
MIT - See repository for details
## Disclaimer
Research model. Not for clinical use without independent validation.