Datasets:

ichorbio
/

biosimilar-reference-database

license: cc-by-4.0
pretty_name: ichorbio Biosimilar Reference Database
tags:
  - biology
  - proteins
  - antibodies
  - biosimilars
  - bioinformatics
  - developability
size_categories:
  - n<1K

ichorbio Biosimilar Reference Database — v0.1.3

Open, citable developability & biophysical data for ichorbio's research-grade biosimilars. Structured per the Developer Brief (Antibodies / Samples / Methods / Measurements; one row per value).

What is in v0.1.3 (seed release)

480 antibodies — identity, target + UniProt, isotype/format, heavy + light chain sequences (from IMGT/mAb-DB), ichorbio SKU, product URL and RRID where assigned.
960 theoretical measurements — molecular weight and theoretical pI, computed from the sequence (marked as theoretical, not laboratory values).
SEC-HPLC purity for 82 biosimilars from supplier Certificates of Analysis — 68 as the exact monomer % read from the CoA chromatogram peak table (280 nm main peak), the rest at a

95% specification where no chromatogram is provided.

Added as the supplier's assays arrive (no rebuild needed)

Further developability data — Tm (DSF), HIC, AC-SINS, PSR, and more SEC-HPLC lots — plus raw assay traces. Each new assay is added as rows in measurements.csv, never as new columns.

Files

antibodies.csv · samples.csv · methods.csv · measurements.csv · summary_wide.csv · data_dictionary.csv · sequences.fasta · ichorbio_bsr.json · dataset.jsonld · CITATION.cff · LICENSE.txt · llms.txt · CHANGELOG.md

Source & versions

GitHub (source repository): https://github.com/ichorbio/biosimilar-reference-database
Zenodo (archived, citable): https://doi.org/10.5281/zenodo.23350140

How to cite

ichorbio (2026). ichorbio Biosimilar Reference Database (version 0.1.3) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.23350140

Licence

CC BY 4.0. Data may be reused, including commercially, with attribution to ichorbio.