| --- |
| license: cc-by-4.0 |
| pretty_name: ichorbio Biosimilar Reference Database |
| tags: |
| - biology |
| - proteins |
| - antibodies |
| - biosimilars |
| - bioinformatics |
| - developability |
| size_categories: |
| - n<1K |
| --- |
| |
| # ichorbio Biosimilar Reference Database — v0.1.3 |
|
|
| [](https://doi.org/10.5281/zenodo.23350140) |
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|
| Open, citable developability & biophysical data for ichorbio's research-grade biosimilars. |
| Structured per the Developer Brief (Antibodies / Samples / Methods / Measurements; one row per value). |
|
|
| ## What is in v0.1.3 (seed release) |
| - **480 antibodies** — identity, target + UniProt, isotype/format, heavy + light chain |
| sequences (from IMGT/mAb-DB), ichorbio SKU, product URL and RRID where assigned. |
| - **960 theoretical measurements** — molecular weight and theoretical pI, computed from the |
| sequence (marked as theoretical, not laboratory values). |
| - **SEC-HPLC purity for 82 biosimilars** from supplier Certificates of Analysis — 68 as the |
| exact monomer % read from the CoA chromatogram peak table (280 nm main peak), the rest at a |
| >95% specification where no chromatogram is provided. |
|
|
| ## Added as the supplier's assays arrive (no rebuild needed) |
| Further developability data — Tm (DSF), HIC, AC-SINS, PSR, and more SEC-HPLC lots — plus |
| raw assay traces. Each new assay is added as rows in `measurements.csv`, never as new columns. |
|
|
| ## Files |
| `antibodies.csv` · `samples.csv` · `methods.csv` · `measurements.csv` · `summary_wide.csv` · |
| `data_dictionary.csv` · `sequences.fasta` · `ichorbio_bsr.json` · `dataset.jsonld` · |
| `CITATION.cff` · `LICENSE.txt` · `llms.txt` · `CHANGELOG.md` |
|
|
| ## Source & versions |
| - GitHub (source repository): https://github.com/ichorbio/biosimilar-reference-database |
| - Zenodo (archived, citable): https://doi.org/10.5281/zenodo.23350140 |
|
|
| ## How to cite |
| ichorbio (2026). ichorbio Biosimilar Reference Database (version 0.1.3) [Data set]. |
| Zenodo. https://doi.org/10.5281/zenodo.23350140 |
|
|
| ## Licence |
| CC BY 4.0. Data may be reused, including commercially, with attribution to ichorbio. |
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