petkovich / README.md
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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

petkovich

Mouse blood DNA-methylation age clock built by regression on reduced-representation bisulfite-sequencing CpGs, estimating biological age and shown to be slowed by lifespan-extending interventions such as caloric restriction and dwarfism.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts chronological age
Species Mus musculus
Tissue whole blood
Data type DNA methylation
Model type elastic net regression
Year 2017

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["petkovich"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Petkovich, Daniel A., et al. "Using DNA methylation profiling to evaluate biological age and longevity interventions." Cell metabolism 25.4 (2017): 954-960.

https://doi.org/10.1016/j.cmet.2017.03.016