| library_name: pyaging | |
| tags: | |
| - pyaging | |
| - aging-clock | |
| - biology | |
| - dna-methylation | |
| # petkovich | |
| Mouse blood DNA-methylation age clock built by regression on reduced-representation bisulfite-sequencing CpGs, estimating biological age and shown to be slowed by lifespan-extending interventions such as caloric restriction and dwarfism. | |
| Model weights retain the original authors' terms; the pyaging software license does not relicense them. | |
| | | | | |
| |---|---| | |
| | **Predicts** | chronological age | | |
| | **Species** | Mus musculus | | |
| | **Tissue** | whole blood | | |
| | **Data type** | DNA methylation | | |
| | **Model type** | elastic net regression | | |
| | **Year** | 2017 | | |
| ## Use with pyaging | |
| ```python | |
| import pyaging as pya | |
| pya.pred.predict_age(adata, ["petkovich"]) | |
| ``` | |
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). | |
| ## Citation | |
| Petkovich, Daniel A., et al. "Using DNA methylation profiling to evaluate biological age and longevity interventions." Cell metabolism 25.4 (2017): 954-960. | |
| https://doi.org/10.1016/j.cmet.2017.03.016 | |