| library_name: pyaging | |
| tags: | |
| - pyaging | |
| - aging-clock | |
| - biology | |
| - dna-methylation | |
| # stubbs | |
| Mouse multi-tissue RRBS age predictor: 17,992 common input loci are normalized and reduced to 329 nonzero clock sites, then quadratically calibrated. | |
| Model weights retain the original authors' terms; the pyaging software license does not relicense them. | |
| | | | | |
| |---|---| | |
| | **Predicts** | chronological age | | |
| | **Species** | Mus musculus | | |
| | **Tissue** | multi-tissue, liver, lung, heart, brain cortex, skeletal muscle, cerebellum, spleen | | |
| | **Data type** | DNA methylation | | |
| | **Model type** | quadratically calibrated elastic net regression | | |
| | **Year** | 2017 | | |
| ## Use with pyaging | |
| ```python | |
| import pyaging as pya | |
| pya.pred.predict_age(adata, ["stubbs"]) | |
| ``` | |
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). | |
| ## Citation | |
| Stubbs, T. M., et al. “Multi-tissue DNA methylation age predictor in mouse.” Genome Biology 18: 68 (2017). | |
| https://doi.org/10.1186/s13059-017-1203-5 | |